目的:构建应急标本信息采集系统,评价其在无网络条件下实现重大传染病疫情防控中的标本采集工作的规范性和准确性。方法:采用Sybase Power Builder开发工具,将Microsoft Access作为后台数据库,选取客户端与服务器(C/S)架构模式,以医院...目的:构建应急标本信息采集系统,评价其在无网络条件下实现重大传染病疫情防控中的标本采集工作的规范性和准确性。方法:采用Sybase Power Builder开发工具,将Microsoft Access作为后台数据库,选取客户端与服务器(C/S)架构模式,以医院实验室信息系统(LIS)或第三方系统为基础,构建能够应对重大传染病大规模标本采样工作的应急标本信息采集系统,对比不同标本信息采样方式的应用效果。结果:应急标本采集系统采集信息的信息录入完整率、正确率及时效性均优于手工方式,差异有统计学意义(x^(2)=89.97、109.83,P<0.05)、(t=146.74,P<0.05),提高了标本采集的效率,减少信息差错率,还可降低交叉感染风险,使重大传染病疫情防控中的标本采集工作更加规范和便捷。结论:应急标本信息采集系统在应对重大传染病大规模采样工作中起到重要作用,能够提升工作效率,保障信息的安全性和准确性。展开更多
Background Painful physical symptoms （PPS） may present as a component of major depressive disorder （MDD）.Their effect in Chinese patients has not been investigated.This analysis reports the changes in disease seve...Background Painful physical symptoms （PPS） may present as a component of major depressive disorder （MDD）.Their effect in Chinese patients has not been investigated.This analysis reports the changes in disease severity,treatment patterns, quality of life and outcomes in a Chinese cohort according to the presence （PPS＋） or absence （PPS-）of painful physical symptoms.Methods A subgroup of Chinese patients from a large observational 3-month study of patients from Asian countries and regions of China were classified using the modified Somatic Symptom Inventory （SSI） as PPS＋（mean score≥2） or PPS（mean score 〈2）.Depression severity was assessed with the Clinical Global Impression of Severity （CGI-S） scale and 17-item Hamilton depression rating scale （HAMD17）.Pain severity was measured using a visual analogue scale （VAS）,while the EuroQoL （EQ-5D） assessed patient well-being.Antidepressants were compared with regard to their efficacy.Results Of the 299 Chinese patients enrolled in the study, 105 were classified as PPS＋ （73/105, 70% women）.At baseline, PPS＋ patients reported greater pain severity （VAS, mean （SD）： 49.56 （26.49） vs.16.60 （20.99） for PPS-, P 〈0.01）, were more depressed （HAMD17, mean （SD）： 25.32 （5.47） vs.23.33 （5.24） for PPS-, P=0.002） and had poorer quality of life （EQ-5D Health State, mean （SD）： 38.48 （22.38） vs.49.57 （18.54） for PPS-, P 〈0.001）.PPS＋ patients showed less overall improvement in depressive symptom severity （HAMD17, change from baseline （95% CI）：-17.38（-18.65, -16.12） vs.-19.20 （-20.05,-18.35） for PPS-,P=-0.032; CGI-S, change from baseline （95% CI）： -2.85（-3.11, -2.58） vs.-3.20 （-3.38, -3.02） for PPS-, P=0.044）.Conclusions PPS were less frequent than expected compared with previous studies of Asian populations.PPS＋were associated with greater MDD severity and less improvement than PPS- when antidepressants were given.展开更多
文摘目的:构建应急标本信息采集系统,评价其在无网络条件下实现重大传染病疫情防控中的标本采集工作的规范性和准确性。方法:采用Sybase Power Builder开发工具,将Microsoft Access作为后台数据库,选取客户端与服务器(C/S)架构模式,以医院实验室信息系统(LIS)或第三方系统为基础,构建能够应对重大传染病大规模标本采样工作的应急标本信息采集系统,对比不同标本信息采样方式的应用效果。结果:应急标本采集系统采集信息的信息录入完整率、正确率及时效性均优于手工方式,差异有统计学意义(x^(2)=89.97、109.83,P<0.05)、(t=146.74,P<0.05),提高了标本采集的效率,减少信息差错率,还可降低交叉感染风险,使重大传染病疫情防控中的标本采集工作更加规范和便捷。结论:应急标本信息采集系统在应对重大传染病大规模采样工作中起到重要作用,能够提升工作效率,保障信息的安全性和准确性。
文摘Background Painful physical symptoms （PPS） may present as a component of major depressive disorder （MDD）.Their effect in Chinese patients has not been investigated.This analysis reports the changes in disease severity,treatment patterns, quality of life and outcomes in a Chinese cohort according to the presence （PPS＋） or absence （PPS-）of painful physical symptoms.Methods A subgroup of Chinese patients from a large observational 3-month study of patients from Asian countries and regions of China were classified using the modified Somatic Symptom Inventory （SSI） as PPS＋（mean score≥2） or PPS（mean score 〈2）.Depression severity was assessed with the Clinical Global Impression of Severity （CGI-S） scale and 17-item Hamilton depression rating scale （HAMD17）.Pain severity was measured using a visual analogue scale （VAS）,while the EuroQoL （EQ-5D） assessed patient well-being.Antidepressants were compared with regard to their efficacy.Results Of the 299 Chinese patients enrolled in the study, 105 were classified as PPS＋ （73/105, 70% women）.At baseline, PPS＋ patients reported greater pain severity （VAS, mean （SD）： 49.56 （26.49） vs.16.60 （20.99） for PPS-, P 〈0.01）, were more depressed （HAMD17, mean （SD）： 25.32 （5.47） vs.23.33 （5.24） for PPS-, P=0.002） and had poorer quality of life （EQ-5D Health State, mean （SD）： 38.48 （22.38） vs.49.57 （18.54） for PPS-, P 〈0.001）.PPS＋ patients showed less overall improvement in depressive symptom severity （HAMD17, change from baseline （95% CI）：-17.38（-18.65, -16.12） vs.-19.20 （-20.05,-18.35） for PPS-,P=-0.032; CGI-S, change from baseline （95% CI）： -2.85（-3.11, -2.58） vs.-3.20 （-3.38, -3.02） for PPS-, P=0.044）.Conclusions PPS were less frequent than expected compared with previous studies of Asian populations.PPS＋were associated with greater MDD severity and less improvement than PPS- when antidepressants were given.
