目的运用定量CT研究老年女性腰椎间盘突出症患者和健康体检者腰椎骨密度(bone mineral density,BMD)的差异,探讨骨密度对腰椎间盘突出症的影响。方法选取腰椎间盘突出症患者64例,健康体检者60例作为对照,使用定量CT(quantitative CT,QCT...目的运用定量CT研究老年女性腰椎间盘突出症患者和健康体检者腰椎骨密度(bone mineral density,BMD)的差异,探讨骨密度对腰椎间盘突出症的影响。方法选取腰椎间盘突出症患者64例,健康体检者60例作为对照,使用定量CT(quantitative CT,QCT)测定两组人群腰椎相同部位骨密度,比较分析两组间、组内骨密度值。结果腰椎间盘突出症患者的骨密度值较对照组低,骨量减少及骨质疏松者在腰椎间盘突出症组所占比例较高,但差异无统计学意义(P>0.05)。腰椎间盘突出组中椎间盘邻近上下两椎体间骨密度有差异(P<0.05),而对照组则无明显差异。结论骨密度对腰椎间盘突出症有一定的影响,突出的椎间盘邻近两椎体骨密度存在某种特殊差异可能是造成椎间盘突出的一种原因。展开更多
Lumbar vertebral body(VB) fractures are increasingly common in an ageing population that is at greater risk of osteoporosis and metastasis. This review aims to identify different models, as alternatives to bone minera...Lumbar vertebral body(VB) fractures are increasingly common in an ageing population that is at greater risk of osteoporosis and metastasis. This review aims to identify different models, as alternatives to bone mineral density(BMD), which may be applied in order to predict VB failure load and fracture risk. The most representative models are those that take account of normal spinal kinetics and assess the contribution of the cortical shell to vertebral strength. Overall, predictive models for VB fracture risk should encompass a range of important parameters including BMD, geometric measures and patient-specific factors. As interventions like vertebroplasty increase in popularity for VB fracture treatment and prevention, such models are likely to play a significant role in the clinical decision-making process. More biomechanical research is required, however, to reduce the risks of post-operative adjacent VB fractures.展开更多
文摘目的运用定量CT研究老年女性腰椎间盘突出症患者和健康体检者腰椎骨密度(bone mineral density,BMD)的差异,探讨骨密度对腰椎间盘突出症的影响。方法选取腰椎间盘突出症患者64例,健康体检者60例作为对照,使用定量CT(quantitative CT,QCT)测定两组人群腰椎相同部位骨密度,比较分析两组间、组内骨密度值。结果腰椎间盘突出症患者的骨密度值较对照组低,骨量减少及骨质疏松者在腰椎间盘突出症组所占比例较高,但差异无统计学意义(P>0.05)。腰椎间盘突出组中椎间盘邻近上下两椎体间骨密度有差异(P<0.05),而对照组则无明显差异。结论骨密度对腰椎间盘突出症有一定的影响,突出的椎间盘邻近两椎体骨密度存在某种特殊差异可能是造成椎间盘突出的一种原因。
文摘Lumbar vertebral body(VB) fractures are increasingly common in an ageing population that is at greater risk of osteoporosis and metastasis. This review aims to identify different models, as alternatives to bone mineral density(BMD), which may be applied in order to predict VB failure load and fracture risk. The most representative models are those that take account of normal spinal kinetics and assess the contribution of the cortical shell to vertebral strength. Overall, predictive models for VB fracture risk should encompass a range of important parameters including BMD, geometric measures and patient-specific factors. As interventions like vertebroplasty increase in popularity for VB fracture treatment and prevention, such models are likely to play a significant role in the clinical decision-making process. More biomechanical research is required, however, to reduce the risks of post-operative adjacent VB fractures.
