Introduction: Squamous cell carcinomas of the lip essentially pose a therapeutic management problem. In the West, their treatment is done under general anesthesia and follows the classic rules of oncology. In our cont...Introduction: Squamous cell carcinomas of the lip essentially pose a therapeutic management problem. In the West, their treatment is done under general anesthesia and follows the classic rules of oncology. In our context of exercise, we sometimes have a different attitude dictated by various constraints. Observation: 55-year-old patient with no notable history, seen in consultation for a very large ulcerative-budding lesion on the right 2/3 of the lower lip with mucocutaneous involvement without lymph node findings found on examination. Faced with this suspicious lesion and the patient’s financial difficulties, we decided to operate under local anesthesia to remove this tumor. The oncological excision was followed by immediate plasty using a Camille-Bernard flap with a good immediate aesthetic and functional result and postoperative day 7. The patient was unable to take his surgical specimen to anatomy-pathology and was lost to follow-up due to lack of financial resources. On anatomo-pathological analysis of the surgical specimen, the margins were healthy with confirmation of squamous cell carcinoma (anapathological reading made for scientific interest). Discussion: The particular mentality of certain patients and their difficult financial conditions push us to have an unconventional therapeutic attitude in oncology, but which nevertheless makes it possible to resolve certain problems that we often face. Local anesthesia is possible and realistic in cases like ours and the results can be acceptable and life-saving.展开更多
We herein report a glycogen-rich adenocarcinoma occurring in the lower lip of a 44-year-old female. The lesion appeared as painless slowly growing mass in the right side of the lower lip. Histologically, infil-trative...We herein report a glycogen-rich adenocarcinoma occurring in the lower lip of a 44-year-old female. The lesion appeared as painless slowly growing mass in the right side of the lower lip. Histologically, infil-trative tumor nests with duct-like or pseudocyst structure into the mucosa and/or dermis were ob-served. The basaloid neoplastic cells had granular but occasionally vacuolated cytoplasm with salient reaction of diastase-digestible periodic acid-Schiff, thus indicating that they were glycogen-rich in nature. The tumor cells were positive for CEA, cytokeratin, and S-100 protein, and negative for SMA, alpha-1 antitrypsin, and amylase by immunohistochemistry. The origin of the tumor with infiltrative nests was indistinguishable from salivary gland and skin ap-pendage malignancy. A differential diagnosis of this peculiar neoplasm was discussed.展开更多
文摘Introduction: Squamous cell carcinomas of the lip essentially pose a therapeutic management problem. In the West, their treatment is done under general anesthesia and follows the classic rules of oncology. In our context of exercise, we sometimes have a different attitude dictated by various constraints. Observation: 55-year-old patient with no notable history, seen in consultation for a very large ulcerative-budding lesion on the right 2/3 of the lower lip with mucocutaneous involvement without lymph node findings found on examination. Faced with this suspicious lesion and the patient’s financial difficulties, we decided to operate under local anesthesia to remove this tumor. The oncological excision was followed by immediate plasty using a Camille-Bernard flap with a good immediate aesthetic and functional result and postoperative day 7. The patient was unable to take his surgical specimen to anatomy-pathology and was lost to follow-up due to lack of financial resources. On anatomo-pathological analysis of the surgical specimen, the margins were healthy with confirmation of squamous cell carcinoma (anapathological reading made for scientific interest). Discussion: The particular mentality of certain patients and their difficult financial conditions push us to have an unconventional therapeutic attitude in oncology, but which nevertheless makes it possible to resolve certain problems that we often face. Local anesthesia is possible and realistic in cases like ours and the results can be acceptable and life-saving.
文摘We herein report a glycogen-rich adenocarcinoma occurring in the lower lip of a 44-year-old female. The lesion appeared as painless slowly growing mass in the right side of the lower lip. Histologically, infil-trative tumor nests with duct-like or pseudocyst structure into the mucosa and/or dermis were ob-served. The basaloid neoplastic cells had granular but occasionally vacuolated cytoplasm with salient reaction of diastase-digestible periodic acid-Schiff, thus indicating that they were glycogen-rich in nature. The tumor cells were positive for CEA, cytokeratin, and S-100 protein, and negative for SMA, alpha-1 antitrypsin, and amylase by immunohistochemistry. The origin of the tumor with infiltrative nests was indistinguishable from salivary gland and skin ap-pendage malignancy. A differential diagnosis of this peculiar neoplasm was discussed.
