目的探索极低出生体质量儿不同用氧方式对早产儿视网膜病变(retinopathy of prematurity,ROP)发生的影响,以便更安全地选择用氧方式,减少ROP的发生。方法回顾分析极低出生体质量儿用氧护理信息,收集2005年1月—2008年7月全部极低出生体...目的探索极低出生体质量儿不同用氧方式对早产儿视网膜病变(retinopathy of prematurity,ROP)发生的影响,以便更安全地选择用氧方式,减少ROP的发生。方法回顾分析极低出生体质量儿用氧护理信息,收集2005年1月—2008年7月全部极低出生体质量儿的病历资料,重点记录用氧方式包括给氧途径、时间、浓度,比较不同用氧方式患儿ROP的发生率,以发现可能存在的高危因素。应用SPSS13.0统计软件进行数据处理,运用统计学描述和确切概率检验。结果应用头罩吸氧方式者与未应用者相比,ROP发生率更高(P=0.012);应用机械通气者较未应用者ROP发生率更高(P=0.011)。结论头罩吸氧较其他吸氧方式ROP发生可能性更高,建议在早产儿特别是极低出生体质量儿不选用头罩吸氧方式;机械通气是发生ROP的高危因素,选择应用时应慎重;极低出生体质量儿的用氧安全浓度是否应该低于一般早产儿,是一个值得关注的问题。展开更多
美国儿科学会、妇产科学院及 WHO 认为早产儿是指自末次月经第1日计算，胎龄＜37周（胎龄＜259 d）的新生儿。早产儿根据胎龄划分，将胎龄＜28周的早产儿称为超早产儿（extremely preterm）。近年来，一些欧美发达国家由于其医疗技术先...美国儿科学会、妇产科学院及 WHO 认为早产儿是指自末次月经第1日计算，胎龄＜37周（胎龄＜259 d）的新生儿。早产儿根据胎龄划分，将胎龄＜28周的早产儿称为超早产儿（extremely preterm）。近年来，一些欧美发达国家由于其医疗技术先进等原因，使得更小孕周、更低体质量的超早产儿在宫外存活，存活率可高达71％～87．3％，胎龄之小可达24周甚至20周；国内超早产儿的病死率可达20％～100％，且胎龄＜25周的超早产儿的存活鲜有报道。北京军区总医院附属八一儿童医院极早产 NICU 成功护理1例胎龄24＋6周、体质量750 g 的超早产儿，现将护理干预及效果体会总结如下。展开更多
Low birth weight（LBW） and preterm birth（PB） are associated with newborn mortality and diseases in adulthood.We explored factors related to LBW and PB by conducting a population-based case-control study from Januar...Low birth weight（LBW） and preterm birth（PB） are associated with newborn mortality and diseases in adulthood.We explored factors related to LBW and PB by conducting a population-based case-control study from January 2011 to December 2013 in Wuhan,China.A total of 337 LBW newborn babies,472 PB babies,and 708 babies with normal birth weights and born from term pregnancies were included in this study.Information of newborns and their parents was collected by trained investigators using questionnaires and referring to medical records.Univariate and logistic regression analyses with the stepwise selection method were used to determine the associations of related factors with LBW and PB.Results showed that maternal hypertension（OR=6.78,95% CI：2.27–20.29,P=0.001）,maternal high-risk pregnancy（OR=1.53,95% CI：1.06–2.21,P=0.022）,and maternal fruit intake ≥300 g per day during the first trimester（OR=1.70,95% CI：1.17–2.45,P=0.005） were associated with LBW.BMI ≥24 kg/m^2 of mother prior to delivery（OR=0.48,95% CI：0.32–0.74,P=0.001） and gestation ≥37 weeks（OR=0.01,95% CI：0.00–0.02,P〈0.034） were protective factors for LBW.Maternal hypertension（OR=3.36,95% CI：1.26–8.98,P=0.016）,maternal high-risk pregnancy（OR=4.38,95% CI：3.26–5.88,P〈0.001）,maternal meal intake of only twice per day（OR=1.88,95% CI：1.10–3.20,P=0.021）,and mother liking food with lots of aginomoto and salt（OR=1.60,95% CI：1.02–2.51,P=0.040） were risk factors for PB.BMI ≥24 kg/m^2 of mother prior to delivery（OR=0.66,95% CI：0.47–0.93,P=0.018）,distance of house from road ≥36 meters（OR=0.72,95% CI：0.53– 0.97,P=0.028）,and living in rural area（OR= 0.60,95% CI：0.37–0.99,P=0.047） were protective factors for PB.Our study demonstrated some risk factors and protective factors for LBW and PB,and provided valuable information for the prevention of the conditions among newborns.展开更多
Purpose: Research on clinical application effect of combining very low birth weight newborn (VLBWN) umbilical vein catheterization (UVC) with peripherally inserted central catheter (PICC). Method: 60 cases of VLBWN ch...Purpose: Research on clinical application effect of combining very low birth weight newborn (VLBWN) umbilical vein catheterization (UVC) with peripherally inserted central catheter (PICC). Method: 60 cases of VLBWN checked in our hospital’s ICU are selected and divided into combination group (n = 30) and PICC group (n = 30) according to the random number table. Combination of UVC and PICC is applied on newborn of combination group while only PICC is applied on newborn of PICC group. These two groups’ newborn’s PICC catheterization operation time, PICC indwelling time, weight gain, hospital stays, hospital infection, planned extubation, successful single puncture, adverse events and other indexes are observed. Result: Newborns in combination group have less PICC catheterization operation time and less hospital stays than newborns in PICC group while newborns in combination group have longer PICC indwelling time and greater weight gain than newborns in PICC group. The difference here has statistical significance (p < 0.05). Combination group’s hospital infection ratio (3.33%) is lower than that of PICC group (23.33%). The difference here has statistical significance (p < 0.05). Newborns in combination group have a planned extubation rate of 93.33% and a successful single puncture rate of 93.33%, which are greater than those of newborn in PICC group (respectively 73.33% and 70.00%). The difference here has statistical significance (p < 0.05). Newborns in combination group have an adverse event occurrence rate of 43.33%, lower than that of PICC group (70.00%). The difference here has statistical significance (p < 0.05). Conclusion: Application of combination of UVC and PICC on VLBWN can greatly improve PICC catheterization efficiency and newborn patients’ nutriture and reduce rate of complications, thus, it is worthy of clinical application.展开更多
文摘目的探索极低出生体质量儿不同用氧方式对早产儿视网膜病变(retinopathy of prematurity,ROP)发生的影响,以便更安全地选择用氧方式,减少ROP的发生。方法回顾分析极低出生体质量儿用氧护理信息,收集2005年1月—2008年7月全部极低出生体质量儿的病历资料,重点记录用氧方式包括给氧途径、时间、浓度,比较不同用氧方式患儿ROP的发生率,以发现可能存在的高危因素。应用SPSS13.0统计软件进行数据处理,运用统计学描述和确切概率检验。结果应用头罩吸氧方式者与未应用者相比,ROP发生率更高(P=0.012);应用机械通气者较未应用者ROP发生率更高(P=0.011)。结论头罩吸氧较其他吸氧方式ROP发生可能性更高,建议在早产儿特别是极低出生体质量儿不选用头罩吸氧方式;机械通气是发生ROP的高危因素,选择应用时应慎重;极低出生体质量儿的用氧安全浓度是否应该低于一般早产儿,是一个值得关注的问题。
文摘美国儿科学会、妇产科学院及 WHO 认为早产儿是指自末次月经第1日计算，胎龄＜37周（胎龄＜259 d）的新生儿。早产儿根据胎龄划分，将胎龄＜28周的早产儿称为超早产儿（extremely preterm）。近年来，一些欧美发达国家由于其医疗技术先进等原因，使得更小孕周、更低体质量的超早产儿在宫外存活，存活率可高达71％～87．3％，胎龄之小可达24周甚至20周；国内超早产儿的病死率可达20％～100％，且胎龄＜25周的超早产儿的存活鲜有报道。北京军区总医院附属八一儿童医院极早产 NICU 成功护理1例胎龄24＋6周、体质量750 g 的超早产儿，现将护理干预及效果体会总结如下。
基金supported by the National Natural Science Foundation of China(No.81573235)Health and Family Commission of Wuhan Municipality(No.WG15D20)Science and Technology Bureau of Wuhan Jiang-an District(No.2014111904)
文摘Low birth weight（LBW） and preterm birth（PB） are associated with newborn mortality and diseases in adulthood.We explored factors related to LBW and PB by conducting a population-based case-control study from January 2011 to December 2013 in Wuhan,China.A total of 337 LBW newborn babies,472 PB babies,and 708 babies with normal birth weights and born from term pregnancies were included in this study.Information of newborns and their parents was collected by trained investigators using questionnaires and referring to medical records.Univariate and logistic regression analyses with the stepwise selection method were used to determine the associations of related factors with LBW and PB.Results showed that maternal hypertension（OR=6.78,95% CI：2.27–20.29,P=0.001）,maternal high-risk pregnancy（OR=1.53,95% CI：1.06–2.21,P=0.022）,and maternal fruit intake ≥300 g per day during the first trimester（OR=1.70,95% CI：1.17–2.45,P=0.005） were associated with LBW.BMI ≥24 kg/m^2 of mother prior to delivery（OR=0.48,95% CI：0.32–0.74,P=0.001） and gestation ≥37 weeks（OR=0.01,95% CI：0.00–0.02,P〈0.034） were protective factors for LBW.Maternal hypertension（OR=3.36,95% CI：1.26–8.98,P=0.016）,maternal high-risk pregnancy（OR=4.38,95% CI：3.26–5.88,P〈0.001）,maternal meal intake of only twice per day（OR=1.88,95% CI：1.10–3.20,P=0.021）,and mother liking food with lots of aginomoto and salt（OR=1.60,95% CI：1.02–2.51,P=0.040） were risk factors for PB.BMI ≥24 kg/m^2 of mother prior to delivery（OR=0.66,95% CI：0.47–0.93,P=0.018）,distance of house from road ≥36 meters（OR=0.72,95% CI：0.53– 0.97,P=0.028）,and living in rural area（OR= 0.60,95% CI：0.37–0.99,P=0.047） were protective factors for PB.Our study demonstrated some risk factors and protective factors for LBW and PB,and provided valuable information for the prevention of the conditions among newborns.
文摘Purpose: Research on clinical application effect of combining very low birth weight newborn (VLBWN) umbilical vein catheterization (UVC) with peripherally inserted central catheter (PICC). Method: 60 cases of VLBWN checked in our hospital’s ICU are selected and divided into combination group (n = 30) and PICC group (n = 30) according to the random number table. Combination of UVC and PICC is applied on newborn of combination group while only PICC is applied on newborn of PICC group. These two groups’ newborn’s PICC catheterization operation time, PICC indwelling time, weight gain, hospital stays, hospital infection, planned extubation, successful single puncture, adverse events and other indexes are observed. Result: Newborns in combination group have less PICC catheterization operation time and less hospital stays than newborns in PICC group while newborns in combination group have longer PICC indwelling time and greater weight gain than newborns in PICC group. The difference here has statistical significance (p < 0.05). Combination group’s hospital infection ratio (3.33%) is lower than that of PICC group (23.33%). The difference here has statistical significance (p < 0.05). Newborns in combination group have a planned extubation rate of 93.33% and a successful single puncture rate of 93.33%, which are greater than those of newborn in PICC group (respectively 73.33% and 70.00%). The difference here has statistical significance (p < 0.05). Newborns in combination group have an adverse event occurrence rate of 43.33%, lower than that of PICC group (70.00%). The difference here has statistical significance (p < 0.05). Conclusion: Application of combination of UVC and PICC on VLBWN can greatly improve PICC catheterization efficiency and newborn patients’ nutriture and reduce rate of complications, thus, it is worthy of clinical application.
