Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic inf...Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.展开更多
目的:观察布地奈德(Budeson ide)雾化吸入治疗急性喉炎的效果。方法:将101例急性喉炎患者随机分为两组,分别使用布地奈德雾化吸入、常规(4万单位庆大霉素∶12.5mg泼尼松龙∶20m l 0.9%NaC l溶液)超声雾化吸入,治疗后第7天进行动态喉镜...目的:观察布地奈德(Budeson ide)雾化吸入治疗急性喉炎的效果。方法:将101例急性喉炎患者随机分为两组,分别使用布地奈德雾化吸入、常规(4万单位庆大霉素∶12.5mg泼尼松龙∶20m l 0.9%NaC l溶液)超声雾化吸入,治疗后第7天进行动态喉镜复查及嗓音分析,了解声带恢复情况,比较两种治疗方法的效果。结果:布地奈德和常规超声雾化吸入的两组患者有效率分别为93.9%和78.8%。两组间疗效比较差异有显著性意义(P<0.05)。结论:布地奈德雾化吸入治疗急性喉炎的疗效优于常规超声雾化吸入。展开更多
文摘Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.
文摘目的:观察布地奈德(Budeson ide)雾化吸入治疗急性喉炎的效果。方法:将101例急性喉炎患者随机分为两组,分别使用布地奈德雾化吸入、常规(4万单位庆大霉素∶12.5mg泼尼松龙∶20m l 0.9%NaC l溶液)超声雾化吸入,治疗后第7天进行动态喉镜复查及嗓音分析,了解声带恢复情况,比较两种治疗方法的效果。结果:布地奈德和常规超声雾化吸入的两组患者有效率分别为93.9%和78.8%。两组间疗效比较差异有显著性意义(P<0.05)。结论:布地奈德雾化吸入治疗急性喉炎的疗效优于常规超声雾化吸入。
