Multi-fountional hollow structures have emerged as promising platforms for intelligent drug delivery due to their unique properties,such as high loading capacities and programmed drug release.In particular,hollow mult...Multi-fountional hollow structures have emerged as promising platforms for intelligent drug delivery due to their unique properties,such as high loading capacities and programmed drug release.In particular,hollow multishell structures(HoMSs)with multilevel shell and space can regulate the molecular-level interaction between drugs and materials,so as to achieve the temporal-spatial order and sequential release of drugs.The anisotropic hollow structures can control the drug diffusion process by inducing the macroscopic interface flow through autonomous movement,realizing the targeted drug transport and release.In this paper,a key focus will be HoMSs with their temporal-ordered architectures and anisotropic hollow carriers with directional movement.Their synthesis mechanisms,structure-property relationships,smartly programmed drug delivery and biomedical applications will be discussed,providing insights into designing next-generation intelligent drug carriers.展开更多
针对综采工作面逐渐向智能化方向发展,以实验室综采工作面三机为研究对象,在unity3d平台下通过脚本组件再现三机运动情况。在unity3d平台下建立综采工作面虚拟场景;运用面向对象的编程思想,详细介绍脚本组件控制采煤机、液压支架、刮板...针对综采工作面逐渐向智能化方向发展,以实验室综采工作面三机为研究对象,在unity3d平台下通过脚本组件再现三机运动情况。在unity3d平台下建立综采工作面虚拟场景;运用面向对象的编程思想,详细介绍脚本组件控制采煤机、液压支架、刮板输送机各自的单机仿真以及综采工作面三机的智能协同运动;最后介绍了图形用户界面GUI(Graphical User Interface)的交互控制,通过监控面板实时显示了三机的运动情况及对部分动作的人工控制。本系统在测试过程中运行良好,达到了真实再现综采工作面三机实际工作情况,为以后实现智能生产提供数字化基础的目的。展开更多
基金This work was supported by the National Natural Science Foundation of China(Nos.92163209,21821005 and 51932001)the Beijing Natural Science Foundation,China(No.JQ22004).
文摘Multi-fountional hollow structures have emerged as promising platforms for intelligent drug delivery due to their unique properties,such as high loading capacities and programmed drug release.In particular,hollow multishell structures(HoMSs)with multilevel shell and space can regulate the molecular-level interaction between drugs and materials,so as to achieve the temporal-spatial order and sequential release of drugs.The anisotropic hollow structures can control the drug diffusion process by inducing the macroscopic interface flow through autonomous movement,realizing the targeted drug transport and release.In this paper,a key focus will be HoMSs with their temporal-ordered architectures and anisotropic hollow carriers with directional movement.Their synthesis mechanisms,structure-property relationships,smartly programmed drug delivery and biomedical applications will be discussed,providing insights into designing next-generation intelligent drug carriers.
文摘针对综采工作面逐渐向智能化方向发展,以实验室综采工作面三机为研究对象,在unity3d平台下通过脚本组件再现三机运动情况。在unity3d平台下建立综采工作面虚拟场景;运用面向对象的编程思想,详细介绍脚本组件控制采煤机、液压支架、刮板输送机各自的单机仿真以及综采工作面三机的智能协同运动;最后介绍了图形用户界面GUI(Graphical User Interface)的交互控制,通过监控面板实时显示了三机的运动情况及对部分动作的人工控制。本系统在测试过程中运行良好,达到了真实再现综采工作面三机实际工作情况,为以后实现智能生产提供数字化基础的目的。