A preliminary experiment for triggering a plasma current quench by high Z impurities has been performed on the HL1M tokamak.Using injection of impurity with the higher charge of the nuclei allows us to increase ...A preliminary experiment for triggering a plasma current quench by high Z impurities has been performed on the HL1M tokamak.Using injection of impurity with the higher charge of the nuclei allows us to increase the radiation cooling.It can be a simple and potential approach for decreasing significantly the plasma thermal energy before a disruption and for safe termination of the plasma.展开更多
An improved and practical synthesis of enzalutamide was accomplished in five steps.Starting from 4-bromo-2-fluoro-benzonic acid,a methyl esterification,Ullmann ligation,methyl esterification,ring closing reaction and ...An improved and practical synthesis of enzalutamide was accomplished in five steps.Starting from 4-bromo-2-fluoro-benzonic acid,a methyl esterification,Ullmann ligation,methyl esterification,ring closing reaction and final methyl amidation provided the target in 35% total yield with 99.8% purity.Five identified impurities were also synthesized.This efficient and economical procedure avoids the use of highly toxic reagents and multiple recrystallization operations,which is suitable for further industrialization.展开更多
文摘A preliminary experiment for triggering a plasma current quench by high Z impurities has been performed on the HL1M tokamak.Using injection of impurity with the higher charge of the nuclei allows us to increase the radiation cooling.It can be a simple and potential approach for decreasing significantly the plasma thermal energy before a disruption and for safe termination of the plasma.
基金the 2016 Shanghai Pujiang Talent program (No. 16PJ1432800)China State Institute of Pharmaceutical Institute Industry for financially supporting this program
文摘An improved and practical synthesis of enzalutamide was accomplished in five steps.Starting from 4-bromo-2-fluoro-benzonic acid,a methyl esterification,Ullmann ligation,methyl esterification,ring closing reaction and final methyl amidation provided the target in 35% total yield with 99.8% purity.Five identified impurities were also synthesized.This efficient and economical procedure avoids the use of highly toxic reagents and multiple recrystallization operations,which is suitable for further industrialization.
