The “New Unemployed” consists of young people with low education in the Chinese cities. They differ from the cohorts of their parents because they have no work experiences in any state- or collective-owned enterpris...The “New Unemployed” consists of young people with low education in the Chinese cities. They differ from the cohorts of their parents because they have no work experiences in any state- or collective-owned enterprise, and are subject to completely different policies designated by the government. Investigations of their daily living lead to the conclusion that the “New Unemployed” has gone through a “system withdrawal” process. They are now facing an environment of “system vacuum” that none of other unemployed groups has ever encountered before. The author emphasizes in the paper a strategic employment principle of “For Future Generations” so that focused attention and care can be provided and this toughest challenge in China can be dealt with.展开更多
Objectives: To investigate the mechanism of Liuwei Dihuang Pill (六味地黄丸, LDP) in treating postmenopausal osteoporosis (PMOP) with Shen (Kidney) yin deficiency. Methods: In this study, 205 cases of PMOP wer...Objectives: To investigate the mechanism of Liuwei Dihuang Pill (六味地黄丸, LDP) in treating postmenopausal osteoporosis (PMOP) with Shen (Kidney) yin deficiency. Methods: In this study, 205 cases of PMOP were divided into the PMOP Shen-yin deficiency group (Group A), PMOP Shen-yang deficiency group (Group B), PMOP without Shen deficiency group (Group C), and control group (Group N). Real-time polymerase chain reaction (RT-PCR) and Western blot techniques were used to observe the effects of LDP treatment on the cardiotrophin-like cytokine factor 1 (CLCF1), ankyrin repeat and SOCS box containing 1 (ASB1), and proldneticin 2 (PROK2) genes and the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway. Results: The mRNA (P〈0.05) and protein (P〈0.01) expression levels of the CLCF1 gone in Group A were significantly lower than the corresponding levels in Group N. After LDP treatment for 3 months, the mRNA expression levels of the CLCF1 gone were obviously up-regulated (P〈0.01). After 6-month treatment, the expression levels of CLCF1 mRNA and protein were significantly up-regulated (both P〈0.01), and the average bone density of the top femur had significantly increased (P〈0.05). In vitro, CLCF1 overexpression resulted in a significant increase in the total protein and phosphorylated protein levels of JAK2 and STAT3. Conclusions: The CLCF1 gone is an important gone associated with PMOP Shen-yin deficiency and the therapeutic effects of LDP may be mediated by up-regulation of CLCF1 gone expression and activation of the JAK/STAT signaling pathway.展开更多
One-cell mouse embryos from KM strain and B6C3F1 strain were cultured in M16 medium, in which 2-cell block generally occurs. Embryos of KM strain exhibited 2-cell block, whereas B6C3F1 embryos, which are regarded as a...One-cell mouse embryos from KM strain and B6C3F1 strain were cultured in M16 medium, in which 2-cell block generally occurs. Embryos of KM strain exhibited 2-cell block, whereas B6C3F1 embryos, which are regarded as a nonblocking strain, proceeded to the 4-cell stage in our culture condition. It is often assumed that the block of early development is due to the failure of/ygotic gene activation (ZGA) in cultured embryos. In this study we examined protein synthesis patterns by two-dimensional gel eleetrophoresis of [35 S] methionine radiolabeled 2-cell embryos. Embryos from the blocking strain and the nonblocking strain were compared in their development both in vitro and in vivo. The detection of TRC expression, a marker of ZGA. at 42 h post hCG in KM embryos developed in vitro suggested that ZGA was also initiated even in the 2-cell arrested embryos. Nevertheless, a significant delay of ZGA was observed in KM strain as compared with normally developed B6C3F1 embryos. At the very beginning of major ZGA as early as 36 h post hCG, TRC has already been expressed in B6C3F1 embryos developed in vitro and KM embryos developed in vivo. But for 2-cell blocked KM embryos, TRC was still not detectable even at 38 h post hCG. These evidences suggest that 2-cell-blocked embryos do initiate ZGA, and that 2-cell block phenomenon is due not to the disability in initiating ZGA. but to a delay of ZGA.展开更多
一、现在完成时态句式二、havebeento,havebeen in和havegoneto用法辨析1."havebeento"表示曾经去过某个地方,强调的是去过的经历或旅行的目的地通常与表示地点的名词连用。例如:一I have been to Paris.(我去过巴黎。)一Have...一、现在完成时态句式二、havebeento,havebeen in和havegoneto用法辨析1."havebeento"表示曾经去过某个地方,强调的是去过的经历或旅行的目的地通常与表示地点的名词连用。例如:一I have been to Paris.(我去过巴黎。)一Have you ever been to China?(你曾经去过中国吗?)2."have been in"表示曾经在某个地方待过一段时间,强调的是在某个地方的居住或停留经历。同样也是与表示地点的名词连用。展开更多
Acinetobacter baumannii is an important opportunistic pathogeq in hospital, and tile multidrug-resistant isolates of A. haumannii have been increasingly reported i,a recent years. A num- ber of different mechanisms of...Acinetobacter baumannii is an important opportunistic pathogeq in hospital, and tile multidrug-resistant isolates of A. haumannii have been increasingly reported i,a recent years. A num- ber of different mechanisms of resistance have been reported, some of which are associated with plasmid-mediated acquisition of genes. Therefore, studies on plasmids in A. haumannii have been a hot issue lately. We have performed complete genome sequencing of A. haumannii MDR-TJ, which is a multidrug-resistant isolate. Finalizing the remaining large scaffold of the previous assem- bly, we found a new plasmid pABTJ2, which carries many phage-like elements. The plasmid pAB- TJ2 is a circular double-stranded DNA molecule, which is 110,967 bp in length. We annotated 125 CDSs from pABTJ2 using IMG ER and ZCURVE_V, accounting lbr 88.28% of the whole plasmid sequence. Many phage-like elements and a tRNA-coding gene were detected in pABTJ2, which is rarely reported among A. haumannii. The tRNA gene is specific for asparagine codon GTT, which may be a small chromosomal sequence picked up through incorrect excision during plasmid forma- tion. The phage-like elements may have been acquired during the integration process, as the GC content of the region carrying phage-like elements was higher than that of the adjacent regions. The finding of phage-like elements and tRNA-coding gene in pABTJ2 may provide a novel insight into the study of A. haumannii pan-plasmidome.展开更多
为全面认识和准确汉译英语非限制性定语从句这一语法结构,借助Gone with the Wind(《飘》)源语及其11个汉译本平行语料,在构式语法理论框架下,分析非限制性定语从句中“被说明的对象”和起链接作用的引导词的特点,结合源语和译语库,考...为全面认识和准确汉译英语非限制性定语从句这一语法结构,借助Gone with the Wind(《飘》)源语及其11个汉译本平行语料,在构式语法理论框架下,分析非限制性定语从句中“被说明的对象”和起链接作用的引导词的特点,结合源语和译语库,考察非限制性定语从句的使用及译法规律性。从语篇视角看,非限制性定语从句极大地充实了先行项信息,一方面使语义内容丰满,另一方面便利读者阅读,保证主从句间的黏着性、连贯性,是表现英语层叠嵌套结构的主要方式之一,既满足形合语言的需要,又是形合语言特征的体现;汉语中没有与之相当的语法结构,译语形义共现手段有限。展开更多
The correlation between -94 G/A polymorphism in the dopamine D1 receptor gone and schizophrenia remains poorly understood despite extensive research. This study sought to evaluate the genotypes and allele frequencies ...The correlation between -94 G/A polymorphism in the dopamine D1 receptor gone and schizophrenia remains poorly understood despite extensive research. This study sought to evaluate the genotypes and allele frequencies of the -94 G/A polymorphism in the dopamine D1 receptor gone by real-time PCR using TaqMan fluorescent probes. One hundred and sixty-two patients with schizophrenia and 101 healthy controls living in Shandong province of China were evaluated. Experimental results showed that the G/A genotype distribution was significantly higher in the schizophrenia patients than in healthy controls. The frequencies of G allele and A allele were not significantly different between the schizophrenia patients and the controls. Thus, the -94 G/A polymorphism in the dopamine D1 receptor gone was found to be associated with schizophrenia in a Chinese Han population from Shandong province.展开更多
Most feminist analyses of Scarlett in Gone with the Wind are concerned with how feminism is reflected in Scarlett's personality,while this research pays attention to how her feminist consciousness grow through thr...Most feminist analyses of Scarlett in Gone with the Wind are concerned with how feminism is reflected in Scarlett's personality,while this research pays attention to how her feminist consciousness grow through three stages.展开更多
Gone With the Wind is a historical fiction novel with vivid descriptions of the Old South,the Civil War and the Recon struction.This is an incredibly well written book about the death of old civilization and the strug...Gone With the Wind is a historical fiction novel with vivid descriptions of the Old South,the Civil War and the Recon struction.This is an incredibly well written book about the death of old civilization and the struggles to survive in the new era.It is ultimately the story of one person,Scarlet O'Hara.Scarlet is keeping on changing during the three periods of the novel—her girlhood,the period of the Civil War and the Reconstruction.Through the analysis of the formation and changing of Scarlet’s characters,this paper will make a further elaboration on the Darwinian concept of"survival of the fittest"and feminism.展开更多
Themes are the essence of literary works.Characters are the carriers of the themes.Thus,theme and character are closely connected.This paper mainly concentrates on the explorations of one common theme revealed in the ...Themes are the essence of literary works.Characters are the carriers of the themes.Thus,theme and character are closely connected.This paper mainly concentrates on the explorations of one common theme revealed in the novel-love,delineates the esthetics of life that expectation and pursuit are the persistence of human essence in consciousness,the approval of human desires and the sublimation of human nature.展开更多
The metaphorical meaning of color terms can make language more vivid.The use of metaphorical meaning of color terms in the works by many authors can make it more attractive.The paper discusses the metaphorical meaning...The metaphorical meaning of color terms can make language more vivid.The use of metaphorical meaning of color terms in the works by many authors can make it more attractive.The paper discusses the metaphorical meaning of color terms through data collection and analyzes how the author use the metaphorical meaning of color terms to express cruel war and bright future.展开更多
Abstract:The paper takes the novel"Gone with the Wind"and Fu’s version as an example to analyze and elaborate the phenomenon of information"loss"in the literary translation from different levels a...Abstract:The paper takes the novel"Gone with the Wind"and Fu’s version as an example to analyze and elaborate the phenomenon of information"loss"in the literary translation from different levels and aspects on the basis of Peter Newmark’s theory.展开更多
Hyalomma anatolicum, Hyalomma asiaticum and Hyalomma detritum are wide-spread tick vectors in China. They could transmit a great variety of serious animal and human pathogens, which are great threats to the health of ...Hyalomma anatolicum, Hyalomma asiaticum and Hyalomma detritum are wide-spread tick vectors in China. They could transmit a great variety of serious animal and human pathogens, which are great threats to the health of human beings and the safety of stockbreeding. Most of them are distributed in Xinjiang and Inner Mongolia, and they share similar morphologies. This study is to establish a method for identifying H. anatolicum, H. asiaticum and H. detritum with molecular markers and to revealing the phylogenetic relationship of these ticks. Ticks were collected from domestic animals in Xinjiang and Inner Mongolia autonomous regions and classified by morphological characters. 16S rRNA and mitachondrial cytochrome oxidase subunit I gone (CO1) of ticks were amplified by PCR and subsequently sequenced. Phylogenetic trees were constructed by MEGA 5.0 and Mrbayes 3.2. On the 16S rRNA-based phylogenetic tree, H. anatolicum and H. aisaticum were clustered together with their respective classes. H. detritum was clustered with their respective class and the H. anatolicum, H. asiaticum formed distinct branches on the phylogenetic trees based on the COL The method based on morphology that combined with molecular 16S rRNA and COl seemed a simple and accurate method for species identification of H. anatolicum, H. asiaticum and H. detritum. n展开更多
This experiment sought to observe the migration and distribution of bone mesenchymal stem cells transfected with the cytosine deaminase gone (BMSCs-CD/eGFP) after transplantation in vivo through three pathways. In a...This experiment sought to observe the migration and distribution of bone mesenchymal stem cells transfected with the cytosine deaminase gone (BMSCs-CD/eGFP) after transplantation in vivo through three pathways. In addition, we examined the tropism of these cells to glioma. Intracranial C6 glioma models were established in Sprague-Dawley rats using an intracranial stereotactic inoculation method. When tumors were 7 days old, rats were inoculated with lx106 BMSCs-CD/eGFP cells via the tumor-bearing internal carotid artery, the contralateral hemisphere and the tumor-bearing glioma. Fluorescence microscopy revealed that BMSCs-CD/eGFP exhibited a strong capacity for migration to tumors. BMSCs-CD/eGFP transplanted via the tumor-bearing intemal carotid artery were observed to distribute in glioma tissues. BMSCs-CD/eGFP inoculated via the ipsilateral glioma mainly located within and at the edge of glioma tissues. BMSCs-CD/eGFP inoculated via the contralateral hemisphere mainly distributed at the proximal end of the tumor at the incubation site.展开更多
Zhao Mingye and her colleagues had to labor through the weekend on December 9,2017.The website Guokr.com,where they work,held a unique fair at a shopping mall in downtown Beijing,which attracted tens of thousands of c...Zhao Mingye and her colleagues had to labor through the weekend on December 9,2017.The website Guokr.com,where they work,held a unique fair at a shopping mall in downtown Beijing,which attracted tens of thousands of cultural creation lovers trying to find something they might be interested in.The number of customers far exceeded their expectations.展开更多
文摘The “New Unemployed” consists of young people with low education in the Chinese cities. They differ from the cohorts of their parents because they have no work experiences in any state- or collective-owned enterprise, and are subject to completely different policies designated by the government. Investigations of their daily living lead to the conclusion that the “New Unemployed” has gone through a “system withdrawal” process. They are now facing an environment of “system vacuum” that none of other unemployed groups has ever encountered before. The author emphasizes in the paper a strategic employment principle of “For Future Generations” so that focused attention and care can be provided and this toughest challenge in China can be dealt with.
基金Supported by National Natural Science Foundation of China(Nos.81173280,81302995,81403420)Fujian Medical Innovation project(No.2011-CX-30)+1 种基金Science and Technology Department of Fujian Province autonomous non-profit research institutes topics project(No.2011R1038-5)Fujian Academy of Traditional Chinese autonomous topics Project(No.2012fjzyyk-5)
文摘Objectives: To investigate the mechanism of Liuwei Dihuang Pill (六味地黄丸, LDP) in treating postmenopausal osteoporosis (PMOP) with Shen (Kidney) yin deficiency. Methods: In this study, 205 cases of PMOP were divided into the PMOP Shen-yin deficiency group (Group A), PMOP Shen-yang deficiency group (Group B), PMOP without Shen deficiency group (Group C), and control group (Group N). Real-time polymerase chain reaction (RT-PCR) and Western blot techniques were used to observe the effects of LDP treatment on the cardiotrophin-like cytokine factor 1 (CLCF1), ankyrin repeat and SOCS box containing 1 (ASB1), and proldneticin 2 (PROK2) genes and the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway. Results: The mRNA (P〈0.05) and protein (P〈0.01) expression levels of the CLCF1 gone in Group A were significantly lower than the corresponding levels in Group N. After LDP treatment for 3 months, the mRNA expression levels of the CLCF1 gone were obviously up-regulated (P〈0.01). After 6-month treatment, the expression levels of CLCF1 mRNA and protein were significantly up-regulated (both P〈0.01), and the average bone density of the top femur had significantly increased (P〈0.05). In vitro, CLCF1 overexpression resulted in a significant increase in the total protein and phosphorylated protein levels of JAK2 and STAT3. Conclusions: The CLCF1 gone is an important gone associated with PMOP Shen-yin deficiency and the therapeutic effects of LDP may be mediated by up-regulation of CLCF1 gone expression and activation of the JAK/STAT signaling pathway.
基金supported by grants from Shanghai Scientific Development Foundation(No.01JC14047)National Key Basic Research Project“973”(No.G199905592).
文摘One-cell mouse embryos from KM strain and B6C3F1 strain were cultured in M16 medium, in which 2-cell block generally occurs. Embryos of KM strain exhibited 2-cell block, whereas B6C3F1 embryos, which are regarded as a nonblocking strain, proceeded to the 4-cell stage in our culture condition. It is often assumed that the block of early development is due to the failure of/ygotic gene activation (ZGA) in cultured embryos. In this study we examined protein synthesis patterns by two-dimensional gel eleetrophoresis of [35 S] methionine radiolabeled 2-cell embryos. Embryos from the blocking strain and the nonblocking strain were compared in their development both in vitro and in vivo. The detection of TRC expression, a marker of ZGA. at 42 h post hCG in KM embryos developed in vitro suggested that ZGA was also initiated even in the 2-cell arrested embryos. Nevertheless, a significant delay of ZGA was observed in KM strain as compared with normally developed B6C3F1 embryos. At the very beginning of major ZGA as early as 36 h post hCG, TRC has already been expressed in B6C3F1 embryos developed in vitro and KM embryos developed in vivo. But for 2-cell blocked KM embryos, TRC was still not detectable even at 38 h post hCG. These evidences suggest that 2-cell-blocked embryos do initiate ZGA, and that 2-cell block phenomenon is due not to the disability in initiating ZGA. but to a delay of ZGA.
文摘一、现在完成时态句式二、havebeento,havebeen in和havegoneto用法辨析1."havebeento"表示曾经去过某个地方,强调的是去过的经历或旅行的目的地通常与表示地点的名词连用。例如:一I have been to Paris.(我去过巴黎。)一Have you ever been to China?(你曾经去过中国吗?)2."have been in"表示曾经在某个地方待过一段时间,强调的是在某个地方的居住或停留经历。同样也是与表示地点的名词连用。
基金partially supported by the National Natural Science Foundation of China (Grant Nos. 90408028, 31171238, 30800642 and 10747150)the Program for New Century Excellent Talents in University of China (Grant No. NCET-120396) Tianjin Municipal Natural Science Foundation of China (Grant No. 09JCZDJC17100)
文摘Acinetobacter baumannii is an important opportunistic pathogeq in hospital, and tile multidrug-resistant isolates of A. haumannii have been increasingly reported i,a recent years. A num- ber of different mechanisms of resistance have been reported, some of which are associated with plasmid-mediated acquisition of genes. Therefore, studies on plasmids in A. haumannii have been a hot issue lately. We have performed complete genome sequencing of A. haumannii MDR-TJ, which is a multidrug-resistant isolate. Finalizing the remaining large scaffold of the previous assem- bly, we found a new plasmid pABTJ2, which carries many phage-like elements. The plasmid pAB- TJ2 is a circular double-stranded DNA molecule, which is 110,967 bp in length. We annotated 125 CDSs from pABTJ2 using IMG ER and ZCURVE_V, accounting lbr 88.28% of the whole plasmid sequence. Many phage-like elements and a tRNA-coding gene were detected in pABTJ2, which is rarely reported among A. haumannii. The tRNA gene is specific for asparagine codon GTT, which may be a small chromosomal sequence picked up through incorrect excision during plasmid forma- tion. The phage-like elements may have been acquired during the integration process, as the GC content of the region carrying phage-like elements was higher than that of the adjacent regions. The finding of phage-like elements and tRNA-coding gene in pABTJ2 may provide a novel insight into the study of A. haumannii pan-plasmidome.
文摘为全面认识和准确汉译英语非限制性定语从句这一语法结构,借助Gone with the Wind(《飘》)源语及其11个汉译本平行语料,在构式语法理论框架下,分析非限制性定语从句中“被说明的对象”和起链接作用的引导词的特点,结合源语和译语库,考察非限制性定语从句的使用及译法规律性。从语篇视角看,非限制性定语从句极大地充实了先行项信息,一方面使语义内容丰满,另一方面便利读者阅读,保证主从句间的黏着性、连贯性,是表现英语层叠嵌套结构的主要方式之一,既满足形合语言的需要,又是形合语言特征的体现;汉语中没有与之相当的语法结构,译语形义共现手段有限。
基金the Scientific Foundation of Shandong Population and Family Planning, No. 2006-7
文摘The correlation between -94 G/A polymorphism in the dopamine D1 receptor gone and schizophrenia remains poorly understood despite extensive research. This study sought to evaluate the genotypes and allele frequencies of the -94 G/A polymorphism in the dopamine D1 receptor gone by real-time PCR using TaqMan fluorescent probes. One hundred and sixty-two patients with schizophrenia and 101 healthy controls living in Shandong province of China were evaluated. Experimental results showed that the G/A genotype distribution was significantly higher in the schizophrenia patients than in healthy controls. The frequencies of G allele and A allele were not significantly different between the schizophrenia patients and the controls. Thus, the -94 G/A polymorphism in the dopamine D1 receptor gone was found to be associated with schizophrenia in a Chinese Han population from Shandong province.
文摘Most feminist analyses of Scarlett in Gone with the Wind are concerned with how feminism is reflected in Scarlett's personality,while this research pays attention to how her feminist consciousness grow through three stages.
文摘Gone With the Wind is a historical fiction novel with vivid descriptions of the Old South,the Civil War and the Recon struction.This is an incredibly well written book about the death of old civilization and the struggles to survive in the new era.It is ultimately the story of one person,Scarlet O'Hara.Scarlet is keeping on changing during the three periods of the novel—her girlhood,the period of the Civil War and the Reconstruction.Through the analysis of the formation and changing of Scarlet’s characters,this paper will make a further elaboration on the Darwinian concept of"survival of the fittest"and feminism.
文摘Themes are the essence of literary works.Characters are the carriers of the themes.Thus,theme and character are closely connected.This paper mainly concentrates on the explorations of one common theme revealed in the novel-love,delineates the esthetics of life that expectation and pursuit are the persistence of human essence in consciousness,the approval of human desires and the sublimation of human nature.
文摘The metaphorical meaning of color terms can make language more vivid.The use of metaphorical meaning of color terms in the works by many authors can make it more attractive.The paper discusses the metaphorical meaning of color terms through data collection and analyzes how the author use the metaphorical meaning of color terms to express cruel war and bright future.
文摘Abstract:The paper takes the novel"Gone with the Wind"and Fu’s version as an example to analyze and elaborate the phenomenon of information"loss"in the literary translation from different levels and aspects on the basis of Peter Newmark’s theory.
基金Supported by National Key Technology Research and Development Program ofChina(2012BAK11B04)
文摘Hyalomma anatolicum, Hyalomma asiaticum and Hyalomma detritum are wide-spread tick vectors in China. They could transmit a great variety of serious animal and human pathogens, which are great threats to the health of human beings and the safety of stockbreeding. Most of them are distributed in Xinjiang and Inner Mongolia, and they share similar morphologies. This study is to establish a method for identifying H. anatolicum, H. asiaticum and H. detritum with molecular markers and to revealing the phylogenetic relationship of these ticks. Ticks were collected from domestic animals in Xinjiang and Inner Mongolia autonomous regions and classified by morphological characters. 16S rRNA and mitachondrial cytochrome oxidase subunit I gone (CO1) of ticks were amplified by PCR and subsequently sequenced. Phylogenetic trees were constructed by MEGA 5.0 and Mrbayes 3.2. On the 16S rRNA-based phylogenetic tree, H. anatolicum and H. aisaticum were clustered together with their respective classes. H. detritum was clustered with their respective class and the H. anatolicum, H. asiaticum formed distinct branches on the phylogenetic trees based on the COL The method based on morphology that combined with molecular 16S rRNA and COl seemed a simple and accurate method for species identification of H. anatolicum, H. asiaticum and H. detritum. n
基金the Natural Science Foundation of Liaoning Province, China, No. 20092165
文摘This experiment sought to observe the migration and distribution of bone mesenchymal stem cells transfected with the cytosine deaminase gone (BMSCs-CD/eGFP) after transplantation in vivo through three pathways. In addition, we examined the tropism of these cells to glioma. Intracranial C6 glioma models were established in Sprague-Dawley rats using an intracranial stereotactic inoculation method. When tumors were 7 days old, rats were inoculated with lx106 BMSCs-CD/eGFP cells via the tumor-bearing internal carotid artery, the contralateral hemisphere and the tumor-bearing glioma. Fluorescence microscopy revealed that BMSCs-CD/eGFP exhibited a strong capacity for migration to tumors. BMSCs-CD/eGFP transplanted via the tumor-bearing intemal carotid artery were observed to distribute in glioma tissues. BMSCs-CD/eGFP inoculated via the ipsilateral glioma mainly located within and at the edge of glioma tissues. BMSCs-CD/eGFP inoculated via the contralateral hemisphere mainly distributed at the proximal end of the tumor at the incubation site.
文摘Zhao Mingye and her colleagues had to labor through the weekend on December 9,2017.The website Guokr.com,where they work,held a unique fair at a shopping mall in downtown Beijing,which attracted tens of thousands of cultural creation lovers trying to find something they might be interested in.The number of customers far exceeded their expectations.