In this paper, using the stochastic decomposition and renewal theory we provide the direct method for analysis the departure process of single sever M/G/1 queueing system, and further discuss the departure process of ...In this paper, using the stochastic decomposition and renewal theory we provide the direct method for analysis the departure process of single sever M/G/1 queueing system, and further discuss the departure process of GI/G/1 queueing system. The method provided in this paper is new and concise, which make us see dearly the structure of the departure process of a single server queueing system.展开更多
Based on the number of customers and the server’s workload,this paper proposes a modified Min(N,D)-policy and discusses an M/G/1 queueing model with delayed randomized multiple vacations under such a policy.Applying ...Based on the number of customers and the server’s workload,this paper proposes a modified Min(N,D)-policy and discusses an M/G/1 queueing model with delayed randomized multiple vacations under such a policy.Applying the well-known stochastic decomposition property of the steady-state queue size,the probability generating function of the steady-state queue length distribution is obtained.Moreover,the explicit expressions of the expected queue length and the additional queue length distribution are derived by some algebraic manipulations.Finally,employing the renewal reward theorem,the explicit expression of the long-run expected cost per unit time is given.Furthermore,we analyze the optimal policy for economizing the expected cost and compare the optimal Min(N,D)-policy with the optimal N-policy and the optimal D-policy by using numerical examples.展开更多
By studying the spectrum of the underlying operator corresponding to the exhaustive-service M/G/1 queueing model with single vacations we prove that the time-dependent solution of the model strongly converges to its s...By studying the spectrum of the underlying operator corresponding to the exhaustive-service M/G/1 queueing model with single vacations we prove that the time-dependent solution of the model strongly converges to its steady-state solution.展开更多
Coronary heart disease(CHD) continues to be the greatest mortality risk factor in the developed world. Estrogens are recognized to have great therapeutic potential to treat CHD and other cardiovascular diseases; howev...Coronary heart disease(CHD) continues to be the greatest mortality risk factor in the developed world. Estrogens are recognized to have great therapeutic potential to treat CHD and other cardiovascular diseases; however,a significant array of potentially debilitating side effects continues to limit their use. Moreover,recent clinical trials have indicated that long-term postmenopausal estrogen therapy may actually be detrimental to cardiovascular health. An exciting new development is the finding that the more recently discovered G-protein-coupled estrogen receptor(GPER) is expressed in coronary arteries-both in coronary endothelium and in smooth muscle within the vascular wall. Accumulating evidence indicates that GPER activation dilates coronary arteries and can also inhibit the prolif-eration and migration of coronary smooth muscle cells. Thus,selective GPER activation has the potential to increase coronary blood flow and possibly limit the debilitating consequences of coronary atherosclerotic disease. This review will highlight what is currently known regarding the impact of GPER activation on coronary arteries and the potential signaling mechanisms stimulated by GPER agonists in these vessels. A thorough understanding of GPER function in coronary arteries may promote the development of new therapies that would help alleviate CHD,while limiting the potentially dangerous side effects of estrogen therapy.展开更多
The M/G/1 queueing system with multiclass customer arrivals, fixed feedback, and first come first served policy is considered, where different classes of customers have different arrival rates, service-time distributi...The M/G/1 queueing system with multiclass customer arrivals, fixed feedback, and first come first served policy is considered, where different classes of customers have different arrival rates, service-time distributions, and feedback numbers. The joint probabifity generation function of queue size of each class and the Laplace-Stieltjes transform of the total sojourn time of a customer in each class are presented, which extended the results obtained by Choi B D. The mean queue size of each class and mean total sojourn time of a customer in each class are obtained with this result. The results can be used in computer and communication networks for their performance analysis.展开更多
文摘In this paper, using the stochastic decomposition and renewal theory we provide the direct method for analysis the departure process of single sever M/G/1 queueing system, and further discuss the departure process of GI/G/1 queueing system. The method provided in this paper is new and concise, which make us see dearly the structure of the departure process of a single server queueing system.
基金supported by the National Natural Science Foundation of China(No.71571127)the National Natural Science Youth Foundation of China(No.72001181).
文摘Based on the number of customers and the server’s workload,this paper proposes a modified Min(N,D)-policy and discusses an M/G/1 queueing model with delayed randomized multiple vacations under such a policy.Applying the well-known stochastic decomposition property of the steady-state queue size,the probability generating function of the steady-state queue length distribution is obtained.Moreover,the explicit expressions of the expected queue length and the additional queue length distribution are derived by some algebraic manipulations.Finally,employing the renewal reward theorem,the explicit expression of the long-run expected cost per unit time is given.Furthermore,we analyze the optimal policy for economizing the expected cost and compare the optimal Min(N,D)-policy with the optimal N-policy and the optimal D-policy by using numerical examples.
基金supported by National Natural Science Foundation of China (GrantNo. 10861011)
文摘By studying the spectrum of the underlying operator corresponding to the exhaustive-service M/G/1 queueing model with single vacations we prove that the time-dependent solution of the model strongly converges to its steady-state solution.
基金Supported by The American Heart Association,Texas Affiliate,No.7370061the Center for Chronic Disorders of Aging,PCOM
文摘Coronary heart disease(CHD) continues to be the greatest mortality risk factor in the developed world. Estrogens are recognized to have great therapeutic potential to treat CHD and other cardiovascular diseases; however,a significant array of potentially debilitating side effects continues to limit their use. Moreover,recent clinical trials have indicated that long-term postmenopausal estrogen therapy may actually be detrimental to cardiovascular health. An exciting new development is the finding that the more recently discovered G-protein-coupled estrogen receptor(GPER) is expressed in coronary arteries-both in coronary endothelium and in smooth muscle within the vascular wall. Accumulating evidence indicates that GPER activation dilates coronary arteries and can also inhibit the prolif-eration and migration of coronary smooth muscle cells. Thus,selective GPER activation has the potential to increase coronary blood flow and possibly limit the debilitating consequences of coronary atherosclerotic disease. This review will highlight what is currently known regarding the impact of GPER activation on coronary arteries and the potential signaling mechanisms stimulated by GPER agonists in these vessels. A thorough understanding of GPER function in coronary arteries may promote the development of new therapies that would help alleviate CHD,while limiting the potentially dangerous side effects of estrogen therapy.
基金the National Natural Science Foundation of China (60703094)Mathematical Tianyuan Foundation of China (10626021)
文摘The M/G/1 queueing system with multiclass customer arrivals, fixed feedback, and first come first served policy is considered, where different classes of customers have different arrival rates, service-time distributions, and feedback numbers. The joint probabifity generation function of queue size of each class and the Laplace-Stieltjes transform of the total sojourn time of a customer in each class are presented, which extended the results obtained by Choi B D. The mean queue size of each class and mean total sojourn time of a customer in each class are obtained with this result. The results can be used in computer and communication networks for their performance analysis.