Objectives of this study were to investigate the effects of milk replacer (MR) acidification for free- access feeding on pre- and post-weaning performance, morbidity and mortality of calves. Calves were randomly assig...Objectives of this study were to investigate the effects of milk replacer (MR) acidification for free- access feeding on pre- and post-weaning performance, morbidity and mortality of calves. Calves were randomly assigned to free-access feeding of acidified (ACID, n = 31) or non-acidified (NON, n = 31) MR, and weaned at 42 days. ACIDMR was prepared to pH 4.0 - 4.5 using formic acid. Intakes were measured daily and weights weekly. Samples of ACID and NON MR were analyzed for coliform and aerobic bacterial growth. After weaning, calves transitioned to a grain-fed veal diet, weighed every 2 weeks. At slaughter (approximately 6 months of age), lungs were evaluated for gross pathological changes and dressed carcass weights were obtained. Generalized linear mixed models were constructed to examine the effects of MR acidification. Differences by treatment group for pre- and post-weaning morbidity and mortality were tested using Pearson’s χ2 and Fisher’s exact tests. ACID calves consumed less MR than NON (10.6 vs. 11.7 L/d, P = 0.02). Acidification tended to promote earlier onset of starter ration consumption (32.0 vs. 39.5 d, hazard ratio = 1.5, P = 0.07), but did not affect average daily starter ration or water intakes across the pre-weaning period. ACID and NON calves did not differ for BW at weaning, pre- or post-weaning ADG or dressed carcass weight. ACID MR had less coliform (P < 0.001) and aerobic bacterial growth (P < 0.001) than NON MR, but odds of disease treatment and mortality did not differ. ACID calves tended to have lower odds of pulmonary lesions during post-mortem inspection than NON calves (OR = 0.3, P = 0.07). These results indicate that under free-access feeding conditions, acidification limited bacterial growth and MR intake, but there were no long-term impacts of acidification on calf performance or health. In conclusion, acidification to pH 4.0 - 4.5 will significantly reduce bacterial growth in milk fed to calves.展开更多
In order to support massive Machine Type Communication(mMTC) applications in future Fifth Generation(5G) systems,a key technical challenge is to design a highly effective multiple access protocol for massive connectio...In order to support massive Machine Type Communication(mMTC) applications in future Fifth Generation(5G) systems,a key technical challenge is to design a highly effective multiple access protocol for massive connection requests and huge traffic load from all kinds of smart devices,e.g.bike,watch,phone,ring,glasses,shoes,etc..To solve this hard problem in distributed scenarios with massive competing devices,this paper proposes and evaluates a Neighbor-Aware Multiple Access(NAMA) protocol,which is scalable and adaptive to different connectivity size and traffic load.By exploiting acknowledgement signals broadcasted from the neighboring devices with successful packet transmissions,NAMA is able to turn itself from a contention-based random access protocol to become a contention-free deterministic access protocol with particular transmission schedules for all neighboring devices after a short transition period.The performance of NAMA is fully evaluated from random state to deterministic state through extensive computer simulations under different network sizes and Contention Window(CW)settings.Compared with traditional IEEE802.11 Distributed Coordination Function(DCF),for a crowded network with 50 devices,NAMA can greatly improve system throughput and energy efficiency by more than 110%and210%,respectively,while reducing average access delay by 53%in the deterministic state.展开更多
文摘Objectives of this study were to investigate the effects of milk replacer (MR) acidification for free- access feeding on pre- and post-weaning performance, morbidity and mortality of calves. Calves were randomly assigned to free-access feeding of acidified (ACID, n = 31) or non-acidified (NON, n = 31) MR, and weaned at 42 days. ACIDMR was prepared to pH 4.0 - 4.5 using formic acid. Intakes were measured daily and weights weekly. Samples of ACID and NON MR were analyzed for coliform and aerobic bacterial growth. After weaning, calves transitioned to a grain-fed veal diet, weighed every 2 weeks. At slaughter (approximately 6 months of age), lungs were evaluated for gross pathological changes and dressed carcass weights were obtained. Generalized linear mixed models were constructed to examine the effects of MR acidification. Differences by treatment group for pre- and post-weaning morbidity and mortality were tested using Pearson’s χ2 and Fisher’s exact tests. ACID calves consumed less MR than NON (10.6 vs. 11.7 L/d, P = 0.02). Acidification tended to promote earlier onset of starter ration consumption (32.0 vs. 39.5 d, hazard ratio = 1.5, P = 0.07), but did not affect average daily starter ration or water intakes across the pre-weaning period. ACID and NON calves did not differ for BW at weaning, pre- or post-weaning ADG or dressed carcass weight. ACID MR had less coliform (P < 0.001) and aerobic bacterial growth (P < 0.001) than NON MR, but odds of disease treatment and mortality did not differ. ACID calves tended to have lower odds of pulmonary lesions during post-mortem inspection than NON calves (OR = 0.3, P = 0.07). These results indicate that under free-access feeding conditions, acidification limited bacterial growth and MR intake, but there were no long-term impacts of acidification on calf performance or health. In conclusion, acidification to pH 4.0 - 4.5 will significantly reduce bacterial growth in milk fed to calves.
基金funded by the National Natural Science Foundation of China (Grant No.61231009)the National HighTech R&D Program of China(863)(Grant No.2014AA01A701)+5 种基金the National Science and Technology Major Project(Grant No. 2015ZX03001033-003)Ministry of Science and Technology International Cooperation Project(Grant No.2014DFE10160)the Science and Technology Commission of Shanghai Municipality(Grant No.14ZR1439600)the EU H2020 5G Wireless project(Grant No.641985)the EU FP7 QUICK project(Grant No. PIRSES-GA-2013-612652)the EPSRC TOUCAN project(Grant No.EP/L020009/1)
文摘In order to support massive Machine Type Communication(mMTC) applications in future Fifth Generation(5G) systems,a key technical challenge is to design a highly effective multiple access protocol for massive connection requests and huge traffic load from all kinds of smart devices,e.g.bike,watch,phone,ring,glasses,shoes,etc..To solve this hard problem in distributed scenarios with massive competing devices,this paper proposes and evaluates a Neighbor-Aware Multiple Access(NAMA) protocol,which is scalable and adaptive to different connectivity size and traffic load.By exploiting acknowledgement signals broadcasted from the neighboring devices with successful packet transmissions,NAMA is able to turn itself from a contention-based random access protocol to become a contention-free deterministic access protocol with particular transmission schedules for all neighboring devices after a short transition period.The performance of NAMA is fully evaluated from random state to deterministic state through extensive computer simulations under different network sizes and Contention Window(CW)settings.Compared with traditional IEEE802.11 Distributed Coordination Function(DCF),for a crowded network with 50 devices,NAMA can greatly improve system throughput and energy efficiency by more than 110%and210%,respectively,while reducing average access delay by 53%in the deterministic state.