BACKGROUND：Gallbladder adenoma is a pre-cancerous neoplasm and needs surgical resection.It is difficult to differentiate adenoma from other gallbladder polyps using imaging examinations.The study aimed to illustrate ...BACKGROUND：Gallbladder adenoma is a pre-cancerous neoplasm and needs surgical resection.It is difficult to differentiate adenoma from other gallbladder polyps using imaging examinations.The study aimed to illustrate characteristics of contrast-enhanced ultrasound（CEUS）and its diagnostic value in gallbladder adenoma.METHODS： Thirty-seven patients with 39 gallbladder adenoma- toid lesions （maximal diameter _〉10 mm and without metastasis） were enrolled in this study. Lesion appearances in conventional ultrasound and CEUS were documented. The imaging features were compared individuaUy among gallbladder cholesterol polyp, gallbladder adenoma and malignant lesion. RESULTS： Adenoma lesions showed iso-echogenicity in ul- trasound, and an eccentric enhancement pattern, ＂fast-in and synchronous-out＂ contrast enhancement pattern and homo- geneous at peak-time enhancement in CEUS. The homogenic- ity at peak-time enhancement showed the highest diagnostic ability in differentiating gallbladder adenoma from cholesterol polyps. The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and Youden index were 100%, 90.9%, 92.9%, 100%, 95.8% and 0.91, respectively. The characteristic of continuous gallbladder wall shown by CEUS had the highest diagnostic ability in differentiating adenoma from malignant lesion （100%, 86.7%, 86.7%, 100%, 92.9% and 0.87, respectively）. The characteristic of the eccentric enhance- ment pattern had the highest diagnostic ability in differenti- ating adenoma from cholesterol polyp and malignant lesion, with corresponding indices of 69.2%, 88.5%, 75.0%, 85.2%, 82.1% and 0.58, respectively.CONCLUSIONS： CEUS is valuable in differentiating gallbladder adenoma from other gallbladder polyps （〉_10 mm in diameter）. Homogeneous echogenicity on peak-time enhancement, a continuous gallbladder wall, and the eccentric enhancement pattern are important indicators of gallbladder adenoma on CEUS.展开更多
The present study evaluated fetal thalamic echogenicity by ultrasound as a possible marker of fetal lung maturity in comparison with other ultrasound makers. A prospective longitudinal study performed in Al-Elwiya Mat...The present study evaluated fetal thalamic echogenicity by ultrasound as a possible marker of fetal lung maturity in comparison with other ultrasound makers. A prospective longitudinal study performed in Al-Elwiya Maternity Teaching Hospital in Baghdad, Iraq during the period from April 2010 to March 2011. One hundred and forty two pregnant women (36 to 42 weeks of gestation) who were admitted for elective cesarean section and referred for an obstetric ultrasound scan at the same day of their elective cesarean section were included. Scanning with linear ultrasound with convex transducer frequency of 3.5 MHz was utilized to measure the biparietal diameter and the state of echogenicity was recorded as echogenic or echolucent, in addition to amniotic fluid vernix and the placental changes. The presence of echogenic thalamus as a sign of fetal lung maturity had a specificity of 86.53% which is higher than the three other signs of lung maturity;the positive predictive value was (89.6%) which is also higher than the three other signs, but the sensitivity was 63.33% and negative predictive value was 57.69% which is lower than the presence of vernix in the amniotic fluid, 86.66 and 67.56 respectively. In conclusion, evaluation of echogenic thalamus is beneficial, and can be considered as a new marker of fetal lung maturity;however, further studies are required to strengthen such idea.展开更多
It has been reported that overweight Japanese males have poorly organised dermis and their skin may be fragile to external forces because of decreased dermal echogenicity. However, it is unknown whether the changes in...It has been reported that overweight Japanese males have poorly organised dermis and their skin may be fragile to external forces because of decreased dermal echogenicity. However, it is unknown whether the changes in the dermal structure actually affect the dermal function. The objective of this study was to clarify the relationship between dermal structural parameters and dermal functional parameters in overweight and obese Japanese males. A cross-sectional, observational study was conducted on Japanese male volunteers. Two ultrasound scanners, a 20-MHz Dermascan C<sup>®</sup> and an 18-MHz Mylab<sup>TM</sup> five<sup>®</sup> were used to evaluate dermal structure. Echogenicity of the lower dermis and dermal thickness of the participants’ abdomens and thighs were measured. A Cutometer<sup>®</sup> MPA580 was used to evaluate skin viscoelasticity, skin deformation (R0) and elasticity (R2, R7). The correlation between dermal structural parameters and skin viscoelasticity were validated using Pearson’s correlation coefficient or Spearman’s correlation coefficient by rank test. A total of 79 male volunteers were recruited of which 43 were control subjects with BMI <25 (age, 22 - 63 years), 25 were overweight subjects with BMI ≥ 25 to <30 (age, 23 - 64 years) and the 11 obese subjects had a BMI ≥ 30 (age, 26 - 47 years). There was no correlation between dermal structural parameters and skin viscoelasticity in the abdomens or thighs of all 79 participants. On the other hand, in the 36 overweight and obese participants, thigh dermal echogenicity was significantly and negatively correlated with R0 (r = -0.456, p < 0.01) and dermal thickness in the abdomen was significantly and positively correlated with R0 (r = 0.464, p < 0.01). The dermal functional parameter was significantly correlated with dermal structural parameters in overweight and obese males;in other words, a decrease in dermal function may be caused by structural changes in the dermis during obesity.展开更多
目的:探讨超声诊断弥漫性胰腺回声增强的临床意义,分析胰腺回声与血脂、血糖等生化指标关系。方法:选取2019年1月—2021年12月在成武县人民医院进行健康体检的7292例受检者,超声诊断为弥漫性胰腺回声增强患者共256例为病例组,并随机选...目的:探讨超声诊断弥漫性胰腺回声增强的临床意义,分析胰腺回声与血脂、血糖等生化指标关系。方法:选取2019年1月—2021年12月在成武县人民医院进行健康体检的7292例受检者,超声诊断为弥漫性胰腺回声增强患者共256例为病例组,并随机选取同期胰腺回声正常者1020名作为对照组,整理受检者超声及实验室检查资料,分析两组患者间高血脂、高血糖发生率的差异;进一步探讨胰腺回声强度与血脂、血糖、体重指数等指标相关性。结果:病例组与对照组间性别及高密度脂蛋白(high density lipoprotein,HDL)水平差异均不显著(P>0.05)。病例组空腹高血糖、高胆固醇、高甘油三酯的发生率均高于对照组(22.5%vs7.9%、12.3%vs5.9%、55.2%vs17.3%),差异具有统计学意义(P<0.05);病例组TC、TG、LDL、BMI及空腹血糖水平均较对照组显著升高(P<0.05)。胰腺回声强度与TC、TG及LDL、BMI等呈正相关关系(P<0.05)。控制性别后,偏相关显示胰腺回声强度仍与TG、LDL、BMI及血糖水平呈显著正相关关系(P<0.05),回声强度与TG相关性最强(r=0.597,P<0.01)。结论:超声诊断弥漫性胰腺回声增强对于提示无症状性高血脂、高血糖有重要的临床价值,可为临床预防提供重要依据。展开更多
基金supported by a grant from the National Natural Science Foundation of China(81371577)
文摘BACKGROUND：Gallbladder adenoma is a pre-cancerous neoplasm and needs surgical resection.It is difficult to differentiate adenoma from other gallbladder polyps using imaging examinations.The study aimed to illustrate characteristics of contrast-enhanced ultrasound（CEUS）and its diagnostic value in gallbladder adenoma.METHODS： Thirty-seven patients with 39 gallbladder adenoma- toid lesions （maximal diameter _〉10 mm and without metastasis） were enrolled in this study. Lesion appearances in conventional ultrasound and CEUS were documented. The imaging features were compared individuaUy among gallbladder cholesterol polyp, gallbladder adenoma and malignant lesion. RESULTS： Adenoma lesions showed iso-echogenicity in ul- trasound, and an eccentric enhancement pattern, ＂fast-in and synchronous-out＂ contrast enhancement pattern and homo- geneous at peak-time enhancement in CEUS. The homogenic- ity at peak-time enhancement showed the highest diagnostic ability in differentiating gallbladder adenoma from cholesterol polyps. The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and Youden index were 100%, 90.9%, 92.9%, 100%, 95.8% and 0.91, respectively. The characteristic of continuous gallbladder wall shown by CEUS had the highest diagnostic ability in differentiating adenoma from malignant lesion （100%, 86.7%, 86.7%, 100%, 92.9% and 0.87, respectively）. The characteristic of the eccentric enhance- ment pattern had the highest diagnostic ability in differenti- ating adenoma from cholesterol polyp and malignant lesion, with corresponding indices of 69.2%, 88.5%, 75.0%, 85.2%, 82.1% and 0.58, respectively.CONCLUSIONS： CEUS is valuable in differentiating gallbladder adenoma from other gallbladder polyps （〉_10 mm in diameter）. Homogeneous echogenicity on peak-time enhancement, a continuous gallbladder wall, and the eccentric enhancement pattern are important indicators of gallbladder adenoma on CEUS.
文摘The present study evaluated fetal thalamic echogenicity by ultrasound as a possible marker of fetal lung maturity in comparison with other ultrasound makers. A prospective longitudinal study performed in Al-Elwiya Maternity Teaching Hospital in Baghdad, Iraq during the period from April 2010 to March 2011. One hundred and forty two pregnant women (36 to 42 weeks of gestation) who were admitted for elective cesarean section and referred for an obstetric ultrasound scan at the same day of their elective cesarean section were included. Scanning with linear ultrasound with convex transducer frequency of 3.5 MHz was utilized to measure the biparietal diameter and the state of echogenicity was recorded as echogenic or echolucent, in addition to amniotic fluid vernix and the placental changes. The presence of echogenic thalamus as a sign of fetal lung maturity had a specificity of 86.53% which is higher than the three other signs of lung maturity;the positive predictive value was (89.6%) which is also higher than the three other signs, but the sensitivity was 63.33% and negative predictive value was 57.69% which is lower than the presence of vernix in the amniotic fluid, 86.66 and 67.56 respectively. In conclusion, evaluation of echogenic thalamus is beneficial, and can be considered as a new marker of fetal lung maturity;however, further studies are required to strengthen such idea.
文摘It has been reported that overweight Japanese males have poorly organised dermis and their skin may be fragile to external forces because of decreased dermal echogenicity. However, it is unknown whether the changes in the dermal structure actually affect the dermal function. The objective of this study was to clarify the relationship between dermal structural parameters and dermal functional parameters in overweight and obese Japanese males. A cross-sectional, observational study was conducted on Japanese male volunteers. Two ultrasound scanners, a 20-MHz Dermascan C<sup>®</sup> and an 18-MHz Mylab<sup>TM</sup> five<sup>®</sup> were used to evaluate dermal structure. Echogenicity of the lower dermis and dermal thickness of the participants’ abdomens and thighs were measured. A Cutometer<sup>®</sup> MPA580 was used to evaluate skin viscoelasticity, skin deformation (R0) and elasticity (R2, R7). The correlation between dermal structural parameters and skin viscoelasticity were validated using Pearson’s correlation coefficient or Spearman’s correlation coefficient by rank test. A total of 79 male volunteers were recruited of which 43 were control subjects with BMI <25 (age, 22 - 63 years), 25 were overweight subjects with BMI ≥ 25 to <30 (age, 23 - 64 years) and the 11 obese subjects had a BMI ≥ 30 (age, 26 - 47 years). There was no correlation between dermal structural parameters and skin viscoelasticity in the abdomens or thighs of all 79 participants. On the other hand, in the 36 overweight and obese participants, thigh dermal echogenicity was significantly and negatively correlated with R0 (r = -0.456, p < 0.01) and dermal thickness in the abdomen was significantly and positively correlated with R0 (r = 0.464, p < 0.01). The dermal functional parameter was significantly correlated with dermal structural parameters in overweight and obese males;in other words, a decrease in dermal function may be caused by structural changes in the dermis during obesity.
文摘目的:探讨超声诊断弥漫性胰腺回声增强的临床意义,分析胰腺回声与血脂、血糖等生化指标关系。方法:选取2019年1月—2021年12月在成武县人民医院进行健康体检的7292例受检者,超声诊断为弥漫性胰腺回声增强患者共256例为病例组,并随机选取同期胰腺回声正常者1020名作为对照组,整理受检者超声及实验室检查资料,分析两组患者间高血脂、高血糖发生率的差异;进一步探讨胰腺回声强度与血脂、血糖、体重指数等指标相关性。结果:病例组与对照组间性别及高密度脂蛋白(high density lipoprotein,HDL)水平差异均不显著(P>0.05)。病例组空腹高血糖、高胆固醇、高甘油三酯的发生率均高于对照组(22.5%vs7.9%、12.3%vs5.9%、55.2%vs17.3%),差异具有统计学意义(P<0.05);病例组TC、TG、LDL、BMI及空腹血糖水平均较对照组显著升高(P<0.05)。胰腺回声强度与TC、TG及LDL、BMI等呈正相关关系(P<0.05)。控制性别后,偏相关显示胰腺回声强度仍与TG、LDL、BMI及血糖水平呈显著正相关关系(P<0.05),回声强度与TG相关性最强(r=0.597,P<0.01)。结论:超声诊断弥漫性胰腺回声增强对于提示无症状性高血脂、高血糖有重要的临床价值,可为临床预防提供重要依据。
