Objective:To compare the therapeutic effect difference among dog-day moxibustion on herbs,ordinary moxibution and routine western medication in treating knee-joint osteoarthritis of yang deficiency and congealing cold...Objective:To compare the therapeutic effect difference among dog-day moxibustion on herbs,ordinary moxibution and routine western medication in treating knee-joint osteoarthritis of yang deficiency and congealing cold type.Methods:A total of 90 patients with knee-joint osteoarthritis of yang deficiency and congealing cold type were divided into dog-day moxibustion group,ordinary moxibution group and western medication group according to the registration order,and there were 30 patients in each group.Among them,the patients in the dog-day moxibustion were given dog-day moxibustion on herbs method during the dog days of 2018(July 17 to August 25).Continuous treatment was applied on the first,second and third dog-day with 5 days for each dog-day,and once for a day,and there were totally 15 times of treatment.In the same period,the patients in the ordinary moxibustion group was treated with the pure moxa stick moxibustion,and the point selection and treatment course were the same as the dog-day moxibustion group.And in the same period,the patients in the western medication group were treated with routine western medication,and the patient took orally diclofenac sodium sustained-release capsules,with 100 mg each time,once a day.The Visual Analog Scale(VAS),Western Ontario and McMaster University Arthritis Index(WOMAC),life quality score and clinical efficacy for the knee joint of the three groups before and after treatment were observed.Results:After treatment,the effective rate of the dog-day moxibustion was 93.33%,the effective rate of the ordinary moxibustion group was 83.33%,and the effective rate of the western medication group was 53.33%.Compared with pre-treatment,the VAS scores and WOMAC scores of the patients with KOA in the three groups after treatment decreased,and the differences were statistically significant(all P<0.05).There were also statistically significant differences between the VAS score,total WOMAC score,pain score,joint stiffness score and joint function score of the three groups after treatment展开更多
文摘目的:观察三伏灸配合肠内营养治疗儿童咳嗽变异性哮喘(cough variant asthma,CVA)临床疗效,并探讨其作用机制。方法:120例咳嗽变异性哮喘患者采用随机对照的原则分为观察组、三伏灸组和肠内营养组,每组各40例。三伏灸组给予三伏灸治疗,肠内营养组给予肠内营养治疗,观察组给予肠内营养配合三伏灸治疗。治疗1个疗程后,比较两组患者临床疗效、症状积分、肺功能[第1秒用力呼气量(forced expiratory volume in first second,FEV1)、呼气峰流速值(peak expiratory flow,PEF)]。结果:观察组有效率为95.0%,三伏灸组有效率为85.0%,肠内营养组有效率为77.5%,观察组明显优于三伏灸组和肠内营养组,差异均有统计学意义(P<0.05)。观察组症状总积分、PEF、FEV1、CD3^+、CD4^+、CD4^+/CD8^+、CD8^+、血红蛋白、血清总蛋白、血清蛋白、体质量、肱三头肌皮皱厚度和上臂肌围,优于三伏灸组和肠内营养组,差异有统计学意义(P<0.05)。结论:三伏灸配合肠内营养能明显改善小儿CVA患者的肺功能和临床症状,可能通过调节细胞免疫,提高患者的血红蛋白、血清总蛋白、血清蛋白、体质量、肱三头肌皮皱厚度和上臂肌围等营养状况等机制作用,从而提高临床疗效。
基金Supported by Research Projects of Traditional Chinese Medicine of Hubei Health and Family Planning Commission: ZY2019M035Wuhan Clinical Medical Research Project: WZ14A01
文摘Objective:To compare the therapeutic effect difference among dog-day moxibustion on herbs,ordinary moxibution and routine western medication in treating knee-joint osteoarthritis of yang deficiency and congealing cold type.Methods:A total of 90 patients with knee-joint osteoarthritis of yang deficiency and congealing cold type were divided into dog-day moxibustion group,ordinary moxibution group and western medication group according to the registration order,and there were 30 patients in each group.Among them,the patients in the dog-day moxibustion were given dog-day moxibustion on herbs method during the dog days of 2018(July 17 to August 25).Continuous treatment was applied on the first,second and third dog-day with 5 days for each dog-day,and once for a day,and there were totally 15 times of treatment.In the same period,the patients in the ordinary moxibustion group was treated with the pure moxa stick moxibustion,and the point selection and treatment course were the same as the dog-day moxibustion group.And in the same period,the patients in the western medication group were treated with routine western medication,and the patient took orally diclofenac sodium sustained-release capsules,with 100 mg each time,once a day.The Visual Analog Scale(VAS),Western Ontario and McMaster University Arthritis Index(WOMAC),life quality score and clinical efficacy for the knee joint of the three groups before and after treatment were observed.Results:After treatment,the effective rate of the dog-day moxibustion was 93.33%,the effective rate of the ordinary moxibustion group was 83.33%,and the effective rate of the western medication group was 53.33%.Compared with pre-treatment,the VAS scores and WOMAC scores of the patients with KOA in the three groups after treatment decreased,and the differences were statistically significant(all P<0.05).There were also statistically significant differences between the VAS score,total WOMAC score,pain score,joint stiffness score and joint function score of the three groups after treatment