目的:探讨抗阻运动联合经颅直流电刺激(transcranial direct current stimulation,tDCS)对脑卒中偏瘫患者肢体运动功能的影响。方法:将2016年1月至2017年4月粤北人民医院康复科收治的98例脑卒中稳定期患者随机分为3组,其中常规组33例采...目的:探讨抗阻运动联合经颅直流电刺激(transcranial direct current stimulation,tDCS)对脑卒中偏瘫患者肢体运动功能的影响。方法:将2016年1月至2017年4月粤北人民医院康复科收治的98例脑卒中稳定期患者随机分为3组,其中常规组33例采用常规康复管理方案,电刺激组32例采用"常规康复+tDCS"方案,联合组33例采用"常规康复+tDCS+抗阻运动"方案。比较3组患者肢体运动功能、日常生活能力、神经功能缺损及血清神经肽Y(neuropeptide Y,NPY)和IL-10水平的变化情况。结果:干预后,联合组患者上、下肢Fugl-Meyer运动量表(Fugl-Meyer Motor Scale,FMMS)评分和日常生活能力(activity of daily living,ADL)评分均明显高于对照组与电刺激组,联合组患者神经缺损程度评分量表(Chinese Stroke Scale,CSS)评分明显低于另外2组,联合组NPY和IL-10水平均明显低于另外2组。结论:抗阻运动联合tDCS可有效改善脑卒中偏瘫患者的肢体运动功能,改善其神经缺损症状,且均为无创性操作,值得进一步在临床推广。展开更多
目的运用经颅直流电刺激(transcranial direct current stimulation,tDCS)后效应配合眼针带针运动疗法对中风后肢体运动功能障碍恢复的疗效。方法将120例中风后肢体运动功能障碍患者按随机数字表法分为对照组、治疗1组(眼针带针运动组)...目的运用经颅直流电刺激(transcranial direct current stimulation,tDCS)后效应配合眼针带针运动疗法对中风后肢体运动功能障碍恢复的疗效。方法将120例中风后肢体运动功能障碍患者按随机数字表法分为对照组、治疗1组(眼针带针运动组)、治疗2组(TDCS配合眼针带针运动),各40例。对照组给予单纯运动疗法治疗,治疗1组给予眼针带针运动疗法治疗,治疗2组在给予经颅直流电刺激后立即应用眼针带针运动疗法进行治疗。对比3组患者治疗前后的神经功能缺损评分、简化Fugl-meyer评分量表评分、日常生活能力评定Barthel量表评分及Berg平衡量表评分。结果治疗后3组患者神经功能缺损评分明显下降,且治疗2组下降幅度高于治疗1组高于对照组(P<0.05);治疗后3组患者简化Fugl-meyer肢体运动功能量表评分升高,且治疗2组上升幅度高于治疗1组高于对照组(P<0.05);治疗后3组患者日常生活能力评定Barthel量表分数升高,且治疗2组上升幅度高于治疗1组高于对照组(P<0.05);Berg平衡量表评分升高,且治疗2组上升幅度高于治疗1组高于对照组(P<0.05)。结论运用经颅直流电刺激后效应配合眼针带针康复疗法治疗中风后肢体运动功能障碍,能够进一步增强眼针带针康复疗法的疗效,使患者的运动能力能够明显的增强,显著的改善患者生存质量。展开更多
Introduction: In the last thirty years, brain neuromodulation techniques have been used as an alternative to pharmacological treatment of neurological disorders. Parkinson’s disease (PD) is a neurodegenerative disord...Introduction: In the last thirty years, brain neuromodulation techniques have been used as an alternative to pharmacological treatment of neurological disorders. Parkinson’s disease (PD) is a neurodegenerative disorder leading to bradykinesia, rest tremor, postural changes, and non-motor symptoms such as depression, anxiety, sleep disorders, pain, and cognitive decline that compromises executive functions (EFs), responsible for the orderly execution of behaviors and tasks of daily life and intentional and directed actions. To this date, a few studies with transcranial direct current stimulation (tDCS) have shown beneficial effects in PD patients concerning specific motor and non-motor symptoms, targeting the motor cortex and/or prefrontal regions. Objective: The main objective of this study was to evaluate the effects of left prefrontal tDCS across a broad spectrum of motor and non-motor symptoms of PD using established validated scales. Method: Single-blind randomized clinical trial with 18 volunteers with PD, aged between 45 and 80 years (66.1 ± 9.65), who met inclusion and exclusion criteria. Participants were submitted to assessments of motor and non-motor functions employing psychometric scales and tests to evaluate EFs and were randomly divided into two groups: control (sham stimulation) and experimental (active stimulation). All participants were involved in three separate tDCS sessions. The anode was positioned over the left dorsolateral prefrontal cortex and the cathode over the right supraorbital region, with a direct current intensity of 2 mA, lasting 20 minutes. At the end of the three sessions, all participants were reassessed. Results: Significant effects of tDCS on non-motor functions were observed for cognition (verbal fluency of actions, clock copy test, appointment by visual confrontation, and verbal memory with immediate free recall) and subjective assessment of sleep quality (overall restlessness and discomfort in the arms and legs at night, leg and arm cramps at night and distressing dream展开更多
目的分析经颅直流电刺激联合步态平衡仪治疗老年脑卒中患者的疗效。方法选择2017年6月~2019年6月我院收治的老年首次发病的脑卒中患者70例,按照随机数字法平均分为2组,对照组35例予以经颅直流电刺激治疗,试验组35例予以经颅直流电刺激...目的分析经颅直流电刺激联合步态平衡仪治疗老年脑卒中患者的疗效。方法选择2017年6月~2019年6月我院收治的老年首次发病的脑卒中患者70例,按照随机数字法平均分为2组,对照组35例予以经颅直流电刺激治疗,试验组35例予以经颅直流电刺激联合步态平衡仪治疗,比较2组血液流变学、步行功能、脑卒中患者姿势评定量表(PASS)、Berg平衡量表(BBS)、10 m步行速度测试(10 m WST)、国际合作共济失调评定量表(ICARS)、上肢运动功能评定量表(FMA-UE)及改良Barthel指数(MBI)等指标的差异。结果治疗后,与对照组治疗后比较,试验组红细胞聚集指数、全血高切黏度、血浆黏度及全血低切黏度等血液流变学指标显著降低(P<0.05),步行功能、PASS和BBS评分改善更显著(P<0.05);且试验组较对照组10 m WST显著缩短[(18.86±10.11)s vs(32.26±16.62)s,P<0.05],ICARS评分显著降低[(33.62±8.11)分vs(42.11±9.16)分,P<0.05],FMA-UE和MBI显著升高[(31.20±5.95)分vs(25.55±5.81)分、(68.20±18.18)分vs(50.85±17.62)分,P<0.05]。结论经颅直流电刺激联合步态平衡仪能改善脑卒中患者上肢运动功能,促进日常生活能力提升。展开更多
目的 探讨经颅直流电刺激(transcranial direct current stimulation, t DCS)对纵跳(counter movement jump, CMJ)能力的影响。方法 21名普通大学生(普通大学生组)和17名大学生运动员(运动员组)随机接受脑前额叶区2 m A、20 min的真刺激...目的 探讨经颅直流电刺激(transcranial direct current stimulation, t DCS)对纵跳(counter movement jump, CMJ)能力的影响。方法 21名普通大学生(普通大学生组)和17名大学生运动员(运动员组)随机接受脑前额叶区2 m A、20 min的真刺激(anodic t DCS,a-t DCS)或假刺激(sham t DCS,s-t DCS),采集刺激后即刻及10、20、30、40 min时间点的CMJ运动表现数据。对受试者不同时间点的跳跃高度、加速度、峰值功率、峰值垂直地面反作用力(vertical ground reaction force, v GRF)进行双因素重复测量方差分析(刺激类型×测试时间点)。结果 运动员组,受试者跳跃高度和峰值v GRF的刺激类型×测试时间点交互作用显著,简单效应分析发现a-t DCS后5个时间点的测试数据均显著优于基准值及s-t DCS后(P<0.05);加速度和峰值功率的刺激类型主效应显著。普通大学生组,受试者加速度、峰值功率、峰值v GRF的刺激类型×测试时间点交互作用显著,简单效应分析发现a-t DCS后5个时间点的测试数据均显著优于基准值及s-t DCS后(P<0.05);跳跃高度的刺激类型主效应显著。结论 脑前额叶区a-t DCS能显著改善CMJ完成过程中的多项指标且具有一定的持续性,可以考虑将其作为增强纵跳能力的一种手段。展开更多
文摘目的:探讨抗阻运动联合经颅直流电刺激(transcranial direct current stimulation,tDCS)对脑卒中偏瘫患者肢体运动功能的影响。方法:将2016年1月至2017年4月粤北人民医院康复科收治的98例脑卒中稳定期患者随机分为3组,其中常规组33例采用常规康复管理方案,电刺激组32例采用"常规康复+tDCS"方案,联合组33例采用"常规康复+tDCS+抗阻运动"方案。比较3组患者肢体运动功能、日常生活能力、神经功能缺损及血清神经肽Y(neuropeptide Y,NPY)和IL-10水平的变化情况。结果:干预后,联合组患者上、下肢Fugl-Meyer运动量表(Fugl-Meyer Motor Scale,FMMS)评分和日常生活能力(activity of daily living,ADL)评分均明显高于对照组与电刺激组,联合组患者神经缺损程度评分量表(Chinese Stroke Scale,CSS)评分明显低于另外2组,联合组NPY和IL-10水平均明显低于另外2组。结论:抗阻运动联合tDCS可有效改善脑卒中偏瘫患者的肢体运动功能,改善其神经缺损症状,且均为无创性操作,值得进一步在临床推广。
文摘目的运用经颅直流电刺激(transcranial direct current stimulation,tDCS)后效应配合眼针带针运动疗法对中风后肢体运动功能障碍恢复的疗效。方法将120例中风后肢体运动功能障碍患者按随机数字表法分为对照组、治疗1组(眼针带针运动组)、治疗2组(TDCS配合眼针带针运动),各40例。对照组给予单纯运动疗法治疗,治疗1组给予眼针带针运动疗法治疗,治疗2组在给予经颅直流电刺激后立即应用眼针带针运动疗法进行治疗。对比3组患者治疗前后的神经功能缺损评分、简化Fugl-meyer评分量表评分、日常生活能力评定Barthel量表评分及Berg平衡量表评分。结果治疗后3组患者神经功能缺损评分明显下降,且治疗2组下降幅度高于治疗1组高于对照组(P<0.05);治疗后3组患者简化Fugl-meyer肢体运动功能量表评分升高,且治疗2组上升幅度高于治疗1组高于对照组(P<0.05);治疗后3组患者日常生活能力评定Barthel量表分数升高,且治疗2组上升幅度高于治疗1组高于对照组(P<0.05);Berg平衡量表评分升高,且治疗2组上升幅度高于治疗1组高于对照组(P<0.05)。结论运用经颅直流电刺激后效应配合眼针带针康复疗法治疗中风后肢体运动功能障碍,能够进一步增强眼针带针康复疗法的疗效,使患者的运动能力能够明显的增强,显著的改善患者生存质量。
文摘Introduction: In the last thirty years, brain neuromodulation techniques have been used as an alternative to pharmacological treatment of neurological disorders. Parkinson’s disease (PD) is a neurodegenerative disorder leading to bradykinesia, rest tremor, postural changes, and non-motor symptoms such as depression, anxiety, sleep disorders, pain, and cognitive decline that compromises executive functions (EFs), responsible for the orderly execution of behaviors and tasks of daily life and intentional and directed actions. To this date, a few studies with transcranial direct current stimulation (tDCS) have shown beneficial effects in PD patients concerning specific motor and non-motor symptoms, targeting the motor cortex and/or prefrontal regions. Objective: The main objective of this study was to evaluate the effects of left prefrontal tDCS across a broad spectrum of motor and non-motor symptoms of PD using established validated scales. Method: Single-blind randomized clinical trial with 18 volunteers with PD, aged between 45 and 80 years (66.1 ± 9.65), who met inclusion and exclusion criteria. Participants were submitted to assessments of motor and non-motor functions employing psychometric scales and tests to evaluate EFs and were randomly divided into two groups: control (sham stimulation) and experimental (active stimulation). All participants were involved in three separate tDCS sessions. The anode was positioned over the left dorsolateral prefrontal cortex and the cathode over the right supraorbital region, with a direct current intensity of 2 mA, lasting 20 minutes. At the end of the three sessions, all participants were reassessed. Results: Significant effects of tDCS on non-motor functions were observed for cognition (verbal fluency of actions, clock copy test, appointment by visual confrontation, and verbal memory with immediate free recall) and subjective assessment of sleep quality (overall restlessness and discomfort in the arms and legs at night, leg and arm cramps at night and distressing dream
文摘目的分析经颅直流电刺激联合步态平衡仪治疗老年脑卒中患者的疗效。方法选择2017年6月~2019年6月我院收治的老年首次发病的脑卒中患者70例,按照随机数字法平均分为2组,对照组35例予以经颅直流电刺激治疗,试验组35例予以经颅直流电刺激联合步态平衡仪治疗,比较2组血液流变学、步行功能、脑卒中患者姿势评定量表(PASS)、Berg平衡量表(BBS)、10 m步行速度测试(10 m WST)、国际合作共济失调评定量表(ICARS)、上肢运动功能评定量表(FMA-UE)及改良Barthel指数(MBI)等指标的差异。结果治疗后,与对照组治疗后比较,试验组红细胞聚集指数、全血高切黏度、血浆黏度及全血低切黏度等血液流变学指标显著降低(P<0.05),步行功能、PASS和BBS评分改善更显著(P<0.05);且试验组较对照组10 m WST显著缩短[(18.86±10.11)s vs(32.26±16.62)s,P<0.05],ICARS评分显著降低[(33.62±8.11)分vs(42.11±9.16)分,P<0.05],FMA-UE和MBI显著升高[(31.20±5.95)分vs(25.55±5.81)分、(68.20±18.18)分vs(50.85±17.62)分,P<0.05]。结论经颅直流电刺激联合步态平衡仪能改善脑卒中患者上肢运动功能,促进日常生活能力提升。
文摘目的 探讨经颅直流电刺激(transcranial direct current stimulation, t DCS)对纵跳(counter movement jump, CMJ)能力的影响。方法 21名普通大学生(普通大学生组)和17名大学生运动员(运动员组)随机接受脑前额叶区2 m A、20 min的真刺激(anodic t DCS,a-t DCS)或假刺激(sham t DCS,s-t DCS),采集刺激后即刻及10、20、30、40 min时间点的CMJ运动表现数据。对受试者不同时间点的跳跃高度、加速度、峰值功率、峰值垂直地面反作用力(vertical ground reaction force, v GRF)进行双因素重复测量方差分析(刺激类型×测试时间点)。结果 运动员组,受试者跳跃高度和峰值v GRF的刺激类型×测试时间点交互作用显著,简单效应分析发现a-t DCS后5个时间点的测试数据均显著优于基准值及s-t DCS后(P<0.05);加速度和峰值功率的刺激类型主效应显著。普通大学生组,受试者加速度、峰值功率、峰值v GRF的刺激类型×测试时间点交互作用显著,简单效应分析发现a-t DCS后5个时间点的测试数据均显著优于基准值及s-t DCS后(P<0.05);跳跃高度的刺激类型主效应显著。结论 脑前额叶区a-t DCS能显著改善CMJ完成过程中的多项指标且具有一定的持续性,可以考虑将其作为增强纵跳能力的一种手段。
