This paper proposes an optimized and coordinated model predictive control(MPC) scheme for doublyfed induction generators(DFIGs) with DC-based converter system to improve the efficiency and dynamic performance in DC gr...This paper proposes an optimized and coordinated model predictive control(MPC) scheme for doublyfed induction generators(DFIGs) with DC-based converter system to improve the efficiency and dynamic performance in DC grids. In this configuration, the stator and rotor of the DFIG are connected to the DC bus via voltage source converters, namely, a rotor side converter(RSC) and a stator side converter(SSC). Optimized trajectories for rotorflux and stator current are proposed to minimize Joule losses of the DFIG, which is particularly advantageous at low and moderate torque. The coordinated MPC scheme is applied to overcome the weaknesses of the field-oriented control technique in the rotor flux-oriented frame, which makes the rotor flux stable and the stator current track its reference closely and quickly. Lastly, simulations and experiments are carried out to validate the feasibility of the control scheme and to analyze the steady-state and dynamic performance of the DFIG.展开更多
Dendritic cells (DCs), the most prevalent antigen-presenting cell in vivo, had been widely characterized in the last three decades. DCs are present in almost all tissues of the body and play cardinal roles in recognit...Dendritic cells (DCs), the most prevalent antigen-presenting cell in vivo, had been widely characterized in the last three decades. DCs are present in almost all tissues of the body and play cardinal roles in recognition of microbial agents,autoantigens, allergens and alloantigen. DCs process the microbial agents or their antigens and migrate to lymphoid tissues to present the antigenic peptide to lymphocytes. This leads to activation of antigen-specific lymphocytes. Initially, it was assumed that DCs are principally involved in the induction and maintenance of adaptive immune responses, but now it is evident that DCs also have important roles in innate immunity. These features make DCs very good candidates for therapy against various pathological conditions including malignancies. Initially, DC-based therapy was used in animal models of cancers. Data from these studies inspired considerable optimism and DC-based therapies was started in human cancers 8 years ago. In general,DC-based therapy has been found to be safe in patients with cancers, although few controlled trials have been conducted in this regard. Because the fundamentals principles of human cancers and animal models of cancers are different, the therapeutic efficacy of the ongoing regime of DC-based therapy in cancer patients is not satisfactory. In this review, we covered the various aspects that should be considered for developing better regime of DC-based therapy for human cancers.展开更多
In this research paper, our main objective is to find out the meticulous role of activated dendritic cells （DCs） during the human immunodeficiency virus （HIV） infection process. DCs play a dual role by enhancing b...In this research paper, our main objective is to find out the meticulous role of activated dendritic cells （DCs） during the human immunodeficiency virus （HIV） infection process. DCs play a dual role by enhancing both HIV infection progression, as well as antiviral immune response. To explore the implications of these dual roles, we have formulated our mathematical model and analyzed the model by both analytical and numerical approaches. By using an impulsive differential equation, we have studied the effect of DC-based vaccination. Analytically we have determined the threshold value of drug dosage and dosing interval for optimum levels of injection. We have also investigated the effect of perfect adherence of drug dose on the immune cell count in extreme cases and observed that, systematic drug dose of the immune cells leads to its maximum level.展开更多
甘肃陇南地区直流融冰装置的建成投运,极大地增强了该地区线路抗覆冰能力。应用Matlab软件对330 k V晒都线路搭建仿真模型进行仿真分析和现场电能质量测试结果验证;同时在现场启动过程中,对整流变空载投切,线路重合闸后加速保护误动原...甘肃陇南地区直流融冰装置的建成投运,极大地增强了该地区线路抗覆冰能力。应用Matlab软件对330 k V晒都线路搭建仿真模型进行仿真分析和现场电能质量测试结果验证;同时在现场启动过程中,对整流变空载投切,线路重合闸后加速保护误动原因分析,并给出了解决涌流跳闸措施,有效减少了变电站整流变装置开关跳闸次数,缩短了停电时间,提高了晒都线供电可靠性。展开更多
基金supported by National Natural Science Foundation of China(No.61473170)Key R&D Plan Project of Shandong Province,PRC(No.2016GSF115018)
文摘This paper proposes an optimized and coordinated model predictive control(MPC) scheme for doublyfed induction generators(DFIGs) with DC-based converter system to improve the efficiency and dynamic performance in DC grids. In this configuration, the stator and rotor of the DFIG are connected to the DC bus via voltage source converters, namely, a rotor side converter(RSC) and a stator side converter(SSC). Optimized trajectories for rotorflux and stator current are proposed to minimize Joule losses of the DFIG, which is particularly advantageous at low and moderate torque. The coordinated MPC scheme is applied to overcome the weaknesses of the field-oriented control technique in the rotor flux-oriented frame, which makes the rotor flux stable and the stator current track its reference closely and quickly. Lastly, simulations and experiments are carried out to validate the feasibility of the control scheme and to analyze the steady-state and dynamic performance of the DFIG.
文摘Dendritic cells (DCs), the most prevalent antigen-presenting cell in vivo, had been widely characterized in the last three decades. DCs are present in almost all tissues of the body and play cardinal roles in recognition of microbial agents,autoantigens, allergens and alloantigen. DCs process the microbial agents or their antigens and migrate to lymphoid tissues to present the antigenic peptide to lymphocytes. This leads to activation of antigen-specific lymphocytes. Initially, it was assumed that DCs are principally involved in the induction and maintenance of adaptive immune responses, but now it is evident that DCs also have important roles in innate immunity. These features make DCs very good candidates for therapy against various pathological conditions including malignancies. Initially, DC-based therapy was used in animal models of cancers. Data from these studies inspired considerable optimism and DC-based therapies was started in human cancers 8 years ago. In general,DC-based therapy has been found to be safe in patients with cancers, although few controlled trials have been conducted in this regard. Because the fundamentals principles of human cancers and animal models of cancers are different, the therapeutic efficacy of the ongoing regime of DC-based therapy in cancer patients is not satisfactory. In this review, we covered the various aspects that should be considered for developing better regime of DC-based therapy for human cancers.
基金This research is supported by the Government of India, Ministry of Science and Technology, Mathematical Science Office, No. SR/S4/MS： 558/08 and supported partially by the National Natural Science Foundation of China （No. 11271314） and Plan for Scientific Innovation Talent of Henan Province （No. 144200510021）.
文摘In this research paper, our main objective is to find out the meticulous role of activated dendritic cells （DCs） during the human immunodeficiency virus （HIV） infection process. DCs play a dual role by enhancing both HIV infection progression, as well as antiviral immune response. To explore the implications of these dual roles, we have formulated our mathematical model and analyzed the model by both analytical and numerical approaches. By using an impulsive differential equation, we have studied the effect of DC-based vaccination. Analytically we have determined the threshold value of drug dosage and dosing interval for optimum levels of injection. We have also investigated the effect of perfect adherence of drug dose on the immune cell count in extreme cases and observed that, systematic drug dose of the immune cells leads to its maximum level.
文摘甘肃陇南地区直流融冰装置的建成投运,极大地增强了该地区线路抗覆冰能力。应用Matlab软件对330 k V晒都线路搭建仿真模型进行仿真分析和现场电能质量测试结果验证;同时在现场启动过程中,对整流变空载投切,线路重合闸后加速保护误动原因分析,并给出了解决涌流跳闸措施,有效减少了变电站整流变装置开关跳闸次数,缩短了停电时间,提高了晒都线供电可靠性。
