AIM: To evaluate the frequency of blue-on-yellow perimetry (B/YP) deficits in ocular hypertension (OHT) patients and to correlate these findings with central corneal thickness (CCT), and to investigate the influence o...AIM: To evaluate the frequency of blue-on-yellow perimetry (B/YP) deficits in ocular hypertension (OHT) patients and to correlate these findings with central corneal thickness (CCT), and to investigate the influence of age, refraction and gender on the B/YP results in OHT patients. METHODS: The B/YP and CCT were checked respectively in 72 OHT patients with normal white-on-white perimetry (W/WP) and normal optic nerve head. The B/YP was tested by Octopus 101 automated perimetry using G2 strategy, while the CCT was checked with DGH-550 ultrasound pachymeter. All patients were chosen randomly one eye for statistical analysis, a binary regression model was used to determine the independent contribution of variables included in the model, and the differences of the intraocular pressure (TOP), CCT, age, refraction and gender between the normal B/YP group and abnormal B/YP group were compared. RESULTS: Forty-nine out of 72 patients with OHT showed normal B/YP results, whereas 23 of 72 patients (31.9%) demonstrated abnormal B/YP results. CCT showed a correlation with the B/YP results (B=-0.038, SE=0.019, P=0.044), whereas none of the TOP, age, refraction and gender was found to be correlated with the B/YP results. The mean CCT in OHT patients with abnormal B/YP group was lower than that with normal B/YP group (t=2.066, P=0.043). There was a significant positive correlation between TOP and CCT (R(2)=0.513, P=0.000). CONCLUSION: The mean CCT in OHT patients with abnormal B/YP results was lower than that with normal B/YP results. There was a significant positive correlation between TOP and CCT in OHT patients. The age, refraction and gender didn't influence the B/YP results in OHT patients.展开更多
目的研究准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)对患者视野的影响。方法用Octo-pus101全自动视野计G2程序的TOP/BY分程序对LASIK手术的近视患者于术前、术后6个月行视野检查。结果术后视野的平均敏感度(mean se...目的研究准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)对患者视野的影响。方法用Octo-pus101全自动视野计G2程序的TOP/BY分程序对LASIK手术的近视患者于术前、术后6个月行视野检查。结果术后视野的平均敏感度(mean sensitivity,MS)与术前比较,差异无显著性(P>0.05)。术后视野的指数平均缺损(mean defect,MD)与术前比较,差异有显著性(P<0.01)。手术前、手术后视力与手术前后各自视野MS、MD均无显著相关性(P>0.05)。手术前后MS和MD平均差值与术前屈光度数、角膜切削百分比、激光切削时间、负压吸引时间、瞳孔直径、年龄、性别等行Spearman相关分析显示均无相关性(P>0.05)。结论手术对视网膜和视神经结构和功能影响还不足以导致临床上明显的功能损伤,没有表现出有临床意义的功能改变。LASIK手术前后视野无明显变化,蓝/黄视野计与标准白色视野计检测的视野结果一致,说明两者检测敏感性相当。展开更多
基金Supported by Shanghai Leading Academi Discipline Project, China (No.S30205)Shanghai Municipal Health Bureau Project, China(No.034075)
文摘AIM: To evaluate the frequency of blue-on-yellow perimetry (B/YP) deficits in ocular hypertension (OHT) patients and to correlate these findings with central corneal thickness (CCT), and to investigate the influence of age, refraction and gender on the B/YP results in OHT patients. METHODS: The B/YP and CCT were checked respectively in 72 OHT patients with normal white-on-white perimetry (W/WP) and normal optic nerve head. The B/YP was tested by Octopus 101 automated perimetry using G2 strategy, while the CCT was checked with DGH-550 ultrasound pachymeter. All patients were chosen randomly one eye for statistical analysis, a binary regression model was used to determine the independent contribution of variables included in the model, and the differences of the intraocular pressure (TOP), CCT, age, refraction and gender between the normal B/YP group and abnormal B/YP group were compared. RESULTS: Forty-nine out of 72 patients with OHT showed normal B/YP results, whereas 23 of 72 patients (31.9%) demonstrated abnormal B/YP results. CCT showed a correlation with the B/YP results (B=-0.038, SE=0.019, P=0.044), whereas none of the TOP, age, refraction and gender was found to be correlated with the B/YP results. The mean CCT in OHT patients with abnormal B/YP group was lower than that with normal B/YP group (t=2.066, P=0.043). There was a significant positive correlation between TOP and CCT (R(2)=0.513, P=0.000). CONCLUSION: The mean CCT in OHT patients with abnormal B/YP results was lower than that with normal B/YP results. There was a significant positive correlation between TOP and CCT in OHT patients. The age, refraction and gender didn't influence the B/YP results in OHT patients.
