目的分析北京、重庆、广州三城市儿童哮喘患病情况,为今后儿童哮喘防治工作提供科学依据。方法采用多阶抽样方法分别从北京、重庆、广州抽取0～14岁儿童10372、9846及4072名,采用国际通用的儿童哮喘及变态反应性疾病国际研究(Internatio...目的分析北京、重庆、广州三城市儿童哮喘患病情况,为今后儿童哮喘防治工作提供科学依据。方法采用多阶抽样方法分别从北京、重庆、广州抽取0～14岁儿童10372、9846及4072名,采用国际通用的儿童哮喘及变态反应性疾病国际研究(International Study of Asthma and Allergies in Childhood,ISAAC)调查问卷进行调查,了解三城市儿童哮喘患病情况。结果北京、重庆、广州儿童哮喘患病率分别为3.15%、7.45%及2.09%,3岁以前首次发作的患儿比例分别为57.21%、69.91%及60.00%;北京、重庆、广州哮喘儿童中半数以上近12个月仍有喘息、夜间干咳、运动后干咳等哮喘症状。结论我国儿童哮喘患病仍呈明显上升趋势,大部分哮喘患儿3岁前发病。展开更多
目的系统评价中国大陆成人(≥14岁)哮喘的患病率。方法计算机检索PubMed、Web of Science、CENTRAL、CINAHL、WanFang Data、CBM、CNKI和VIP数据库,搜集有关中国成人哮喘患病率的横断面研究,检索时限均为2000年1月至2019年12月。由2名...目的系统评价中国大陆成人(≥14岁)哮喘的患病率。方法计算机检索PubMed、Web of Science、CENTRAL、CINAHL、WanFang Data、CBM、CNKI和VIP数据库,搜集有关中国成人哮喘患病率的横断面研究,检索时限均为2000年1月至2019年12月。由2名研究者独立筛选文献、提取数据并评价纳入研究的偏倚风险后,采用Stata 15.0软件进行Meta分析。结果共纳入67个横断面研究,包括1381673例研究对象,19871例成年哮喘患者。Meta分析结果显示,中国成人哮喘患病率为1.81%[95%CI(1.59%,2.01%)]。亚组分析结果显示,中国男、女性哮喘患病率分别为1.87%和1.76%;东北、中部、东部、西部地区哮喘患病率分别为2.16%、1.34%、1.63%、2.23%;15~40岁、41~60岁、>60岁的哮喘患病率分别为0.73%、1.53%、2.81%;文盲、小学、初中、高中、大专及以上哮喘患病率分别为3.07%、1.69%、1.46%、1.01%、0.98%;农林牧业人员、工人、公职人员、商业与服务业人员、军人和其他职业哮喘患病率分别为2.23%、2.10%、1.17%、1.45%、1.09%、1.41%;汉族和其他民族哮喘患病率分别为1.41%、1.59%;城市、农村哮喘患病率分别为2.03%、1.99%;2000~2005年、2006~2010年、2011~2015年、2016~2019年哮喘患病率分别为1.22%、2.07%、2.25%、2.62%。结论中国大陆成人哮喘患病率较高,且研究报道的哮喘患病率有逐年升高的趋势。受年龄、性别、地区、学历和职业的影响,哮喘患病率存在差异。展开更多
Objective To analyze the prevalence of asthma and asthma related symptoms among children aged 0-14 years in three Chinese cities and to obtain a crude estimation of the trend of childhood asthma prevalence in China. M...Objective To analyze the prevalence of asthma and asthma related symptoms among children aged 0-14 years in three Chinese cities and to obtain a crude estimation of the trend of childhood asthma prevalence in China. Methods A cross-sectional, population-based survey of prevalence of asthrna was conducted in children aged from 0 to 14 years in 3 major cities of China （Beijing, Chongqing, and Guangzhou） with different geographic locations. All the subjects were randomly selected by a multi-stage sampling method. Three to five schools and kindergartens in 2 urban districts in each city were randomly selected for the survey, and a validated questionnaire that included the core questions of the International Study of Asthma and Allergies in Childhood, Phase III questionnaire and several additional questions were used. All questionnaires were completed by parents or guardians of the selected children. Children whose parents responded affirmatively to the question＂ Has your child ever been diagnosed as asthma by a doctor＂ were recognized as victims of asthma. Results The prevalence of asthma in Beijing, Chongqing, and Guangzhou was 3.15%, 7.45%, and 2.09%, respectively. These values were significantly higher than those obtained 10 years ago in the national epidemiological survey in 2000 which used the same method of investigation and the same diagnotic criteria （x^2=3.938, P=-0.047; 22=73.506, P≤0.001; x^2=11.956, P=0.001, in each city）. Of the asthmatic children 57.21%, 69.91%, and 60.00% had their first attack before the age of 3 in Beijing, Chongqing, and Guangzhou, respectively. Wheezing was the primary clinical manifestation for all asthmatic children, followed by persistent cough and repeated respiratory infections. Both the prevalence of asthma and asthma-related symptoms were statistically higher in males than in females. Conclusion The prevalence of childhood asthma is statistically higher than that 10 years ago in the three Chinese cities.展开更多
文摘目的分析北京、重庆、广州三城市儿童哮喘患病情况,为今后儿童哮喘防治工作提供科学依据。方法采用多阶抽样方法分别从北京、重庆、广州抽取0～14岁儿童10372、9846及4072名,采用国际通用的儿童哮喘及变态反应性疾病国际研究(International Study of Asthma and Allergies in Childhood,ISAAC)调查问卷进行调查,了解三城市儿童哮喘患病情况。结果北京、重庆、广州儿童哮喘患病率分别为3.15%、7.45%及2.09%,3岁以前首次发作的患儿比例分别为57.21%、69.91%及60.00%;北京、重庆、广州哮喘儿童中半数以上近12个月仍有喘息、夜间干咳、运动后干咳等哮喘症状。结论我国儿童哮喘患病仍呈明显上升趋势,大部分哮喘患儿3岁前发病。
文摘目的系统评价中国大陆成人(≥14岁)哮喘的患病率。方法计算机检索PubMed、Web of Science、CENTRAL、CINAHL、WanFang Data、CBM、CNKI和VIP数据库,搜集有关中国成人哮喘患病率的横断面研究,检索时限均为2000年1月至2019年12月。由2名研究者独立筛选文献、提取数据并评价纳入研究的偏倚风险后,采用Stata 15.0软件进行Meta分析。结果共纳入67个横断面研究,包括1381673例研究对象,19871例成年哮喘患者。Meta分析结果显示,中国成人哮喘患病率为1.81%[95%CI(1.59%,2.01%)]。亚组分析结果显示,中国男、女性哮喘患病率分别为1.87%和1.76%;东北、中部、东部、西部地区哮喘患病率分别为2.16%、1.34%、1.63%、2.23%;15~40岁、41~60岁、>60岁的哮喘患病率分别为0.73%、1.53%、2.81%;文盲、小学、初中、高中、大专及以上哮喘患病率分别为3.07%、1.69%、1.46%、1.01%、0.98%;农林牧业人员、工人、公职人员、商业与服务业人员、军人和其他职业哮喘患病率分别为2.23%、2.10%、1.17%、1.45%、1.09%、1.41%;汉族和其他民族哮喘患病率分别为1.41%、1.59%;城市、农村哮喘患病率分别为2.03%、1.99%;2000~2005年、2006~2010年、2011~2015年、2016~2019年哮喘患病率分别为1.22%、2.07%、2.25%、2.62%。结论中国大陆成人哮喘患病率较高,且研究报道的哮喘患病率有逐年升高的趋势。受年龄、性别、地区、学历和职业的影响,哮喘患病率存在差异。
基金supported by the National Science & Technology Pillar Program under the Eleventh Five-Year Plan of China(No.2007BAI24B05)
文摘Objective To analyze the prevalence of asthma and asthma related symptoms among children aged 0-14 years in three Chinese cities and to obtain a crude estimation of the trend of childhood asthma prevalence in China. Methods A cross-sectional, population-based survey of prevalence of asthrna was conducted in children aged from 0 to 14 years in 3 major cities of China （Beijing, Chongqing, and Guangzhou） with different geographic locations. All the subjects were randomly selected by a multi-stage sampling method. Three to five schools and kindergartens in 2 urban districts in each city were randomly selected for the survey, and a validated questionnaire that included the core questions of the International Study of Asthma and Allergies in Childhood, Phase III questionnaire and several additional questions were used. All questionnaires were completed by parents or guardians of the selected children. Children whose parents responded affirmatively to the question＂ Has your child ever been diagnosed as asthma by a doctor＂ were recognized as victims of asthma. Results The prevalence of asthma in Beijing, Chongqing, and Guangzhou was 3.15%, 7.45%, and 2.09%, respectively. These values were significantly higher than those obtained 10 years ago in the national epidemiological survey in 2000 which used the same method of investigation and the same diagnotic criteria （x^2=3.938, P=-0.047; 22=73.506, P≤0.001; x^2=11.956, P=0.001, in each city）. Of the asthmatic children 57.21%, 69.91%, and 60.00% had their first attack before the age of 3 in Beijing, Chongqing, and Guangzhou, respectively. Wheezing was the primary clinical manifestation for all asthmatic children, followed by persistent cough and repeated respiratory infections. Both the prevalence of asthma and asthma-related symptoms were statistically higher in males than in females. Conclusion The prevalence of childhood asthma is statistically higher than that 10 years ago in the three Chinese cities.
