目的:探讨妇科日间手术病房腹腔镜全子宫切除术后超早期拔除导尿管的安全性及可行性。方法:选择妇科日间手术病房拟行腹腔镜全子宫切除患者,按简单随机分组原则分为超早期组和常规组,两组患者均采用妇科日间手术加速康复围手术期照护方...目的:探讨妇科日间手术病房腹腔镜全子宫切除术后超早期拔除导尿管的安全性及可行性。方法:选择妇科日间手术病房拟行腹腔镜全子宫切除患者,按简单随机分组原则分为超早期组和常规组,两组患者均采用妇科日间手术加速康复围手术期照护方案,由妇科日间手术专科护士完成病情评估(意识状态、生命体征、肌力情况、疼痛评分、腹胀程度、恶心呕吐情况),汇报主管医生后超早期组术后2h内拔除导尿管,常规组术后6 h拔除导尿管,收集并比较两组患者的尿潴留、尿管重置、导尿管相关膀胱刺激征、首次下床活动时间、活动不良事件等指标。结果:共纳入156例患者,其中CINⅢ29例,子宫肌瘤97例,子宫腺肌症17例,其他病种13例。超早期组72例,常规组84例。超早期组与常规组患者拔管后首次残余尿量[(11.24±33.12)mL vs (13.37±61.78)m L]、尿潴留发生率[5.56%(4/72)vs 5.95%(5/84)]及尿管重置率[1.39%(1/72) vs 5.96%(5/84)]比较差异无统计学意义(P>0.05);超早期组导尿管相关膀胱刺激征及活动不良事件发生率均低于常规组(P<0.05);超早期组患者首次肛门排气时间和下床活动时间明显早于常规组(P<0.01)。结论:妇科日间病房行腹腔镜全子宫切除患者在充分病情评估后超早期(0~2 h)拔除导尿管是安全可行的,不会增加患者的残余尿量、尿潴留发生风险及尿管重置风险,可降低患者导尿管相关膀胱刺激征及活动不良事件发生率,同时缩短肛门排气和下床活动时间。展开更多
Background and aims:Drug-induced liver injury(DILI)is one of the most serious adverse drug reactions and its incidence has been increasing rapidly.Accumulating evidence suggests that immune activation and systemic inf...Background and aims:Drug-induced liver injury(DILI)is one of the most serious adverse drug reactions and its incidence has been increasing rapidly.Accumulating evidence suggests that immune activation and systemic inflammatory responses are very important in the progression of DILI.Corticosteroids are often used in DILI,but their clinical usefulness remains controversial.We therefore conducted a prospective,randomized controlled study to investigate whether corticosteroid therapy can accelerate recovery and reduce mortality in severe DILI(SDILI).Methods:SDILI patients with total bilirubin?171μmol/L who presented to the Fifth Medical Center of Chinese PLA General Hospital,Beijing from 2016 to 2019 were randomly allocated to prednisolone and control groups.The endpoints were resolution of SDILI,defined as a decrease in total bilirubin of at least 35μmol/L to<171μmol/L,and overall survival at 6 months.Patients in the prednisolone group received prednisolone 60 mg/day therapy for the first 7 days.Patients with a decrease in total bilirubin of more than 35μmol/L on day 8 continued on tapering doses of prednisolone;otherwise,prednisolone was discontinued.Results:On day 8,50.75%(34/67)and 26.47%(18/68)of the participants in the prednisolone and control groups,respectively,achieved the primary endpoint(p¼0.002).However,there was no significant difference in overall survival at 6 months:95.52%(64/67)vs.91.18%(62/68)in the prednisolone and control groups,respectively(p¼0.3).All deaths in both groups occurred in patients who failed to achieve SDILI resolution on day 8.Conclusion:Prednisolone therapy may accelerate the recovery of SDILI.展开更多
The accelerated life test was carded out to investigate the change of spectral transmittance of di-methyl silicon oil and the effects on the electrical performance of silicon solar cell. The di-methyl silicon oil samp...The accelerated life test was carded out to investigate the change of spectral transmittance of di-methyl silicon oil and the effects on the electrical performance of silicon solar cell. The di-methyl silicon oil samples be- fore and after accelerated life test were analyzed by FT-IR, GC-MS and LC-MS. The ring compounds and linear compounds with larger molecular weight were detected. The spectral transmittance of di-methyl silicon oil de- creased because the chromophore and auxochrome of the products made a sunlight receive decrease on the surface of the solar celt, and resulted in the reduction of cell performance. According to the decrease of spectral transmit- tance of di-methyl silicon oil, two recovery methods were proposed. The results showed that extraction was supe- rior to vacuum distillation in recovering the aged di-methyl silicon oil.展开更多
[Objectives]To observe the application effect of the concept of accelerated recovery after surgery(ERAS)on patients undergoing trans-urethral holmium laser enucleation of prostate(HoLEP)during perioperative period.[Me...[Objectives]To observe the application effect of the concept of accelerated recovery after surgery(ERAS)on patients undergoing trans-urethral holmium laser enucleation of prostate(HoLEP)during perioperative period.[Methods]HoLEP patients with benign prostatic hyperplasia admitted to the Department of Urology,Affiliated Hospital of Jinggangshan University from June to December in 2022 were divided into the observation and control group.40 patients in the control group were given perioperative routine nursing,while 40 patients in the observation group were given perioperative systematic nursing under the concept of ERAS.The nursing effect of different measures were evaluated.[Results]The perioperative related indexes of patients in the observation group were lower than those in the control group(P<0.05).The postoperative feeding,exhaust,spontaneous urination,getting out of bed and hematuria stop time of patients in the observation group were all shorter than those in the control group(P<0.05).The IPSS score and RUV of patients in the observation group were significantly lower than those in the control group,while their Qmax was higher than that in the control group(P<0.05).The incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).[Conclusions]The application of perioperative systematic nursing under ERAS concept in HoLEP patients can promote patients rapid recovery and reduce their complications.展开更多
文摘目的:探讨妇科日间手术病房腹腔镜全子宫切除术后超早期拔除导尿管的安全性及可行性。方法:选择妇科日间手术病房拟行腹腔镜全子宫切除患者,按简单随机分组原则分为超早期组和常规组,两组患者均采用妇科日间手术加速康复围手术期照护方案,由妇科日间手术专科护士完成病情评估(意识状态、生命体征、肌力情况、疼痛评分、腹胀程度、恶心呕吐情况),汇报主管医生后超早期组术后2h内拔除导尿管,常规组术后6 h拔除导尿管,收集并比较两组患者的尿潴留、尿管重置、导尿管相关膀胱刺激征、首次下床活动时间、活动不良事件等指标。结果:共纳入156例患者,其中CINⅢ29例,子宫肌瘤97例,子宫腺肌症17例,其他病种13例。超早期组72例,常规组84例。超早期组与常规组患者拔管后首次残余尿量[(11.24±33.12)mL vs (13.37±61.78)m L]、尿潴留发生率[5.56%(4/72)vs 5.95%(5/84)]及尿管重置率[1.39%(1/72) vs 5.96%(5/84)]比较差异无统计学意义(P>0.05);超早期组导尿管相关膀胱刺激征及活动不良事件发生率均低于常规组(P<0.05);超早期组患者首次肛门排气时间和下床活动时间明显早于常规组(P<0.01)。结论:妇科日间病房行腹腔镜全子宫切除患者在充分病情评估后超早期(0~2 h)拔除导尿管是安全可行的,不会增加患者的残余尿量、尿潴留发生风险及尿管重置风险,可降低患者导尿管相关膀胱刺激征及活动不良事件发生率,同时缩短肛门排气和下床活动时间。
基金This work was supported by the Capital Clinical Characteristic Application Research on Funded Projects(No:Z161100000516172)the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(No:ZYYCXTD-C-202005).
文摘Background and aims:Drug-induced liver injury(DILI)is one of the most serious adverse drug reactions and its incidence has been increasing rapidly.Accumulating evidence suggests that immune activation and systemic inflammatory responses are very important in the progression of DILI.Corticosteroids are often used in DILI,but their clinical usefulness remains controversial.We therefore conducted a prospective,randomized controlled study to investigate whether corticosteroid therapy can accelerate recovery and reduce mortality in severe DILI(SDILI).Methods:SDILI patients with total bilirubin?171μmol/L who presented to the Fifth Medical Center of Chinese PLA General Hospital,Beijing from 2016 to 2019 were randomly allocated to prednisolone and control groups.The endpoints were resolution of SDILI,defined as a decrease in total bilirubin of at least 35μmol/L to<171μmol/L,and overall survival at 6 months.Patients in the prednisolone group received prednisolone 60 mg/day therapy for the first 7 days.Patients with a decrease in total bilirubin of more than 35μmol/L on day 8 continued on tapering doses of prednisolone;otherwise,prednisolone was discontinued.Results:On day 8,50.75%(34/67)and 26.47%(18/68)of the participants in the prednisolone and control groups,respectively,achieved the primary endpoint(p¼0.002).However,there was no significant difference in overall survival at 6 months:95.52%(64/67)vs.91.18%(62/68)in the prednisolone and control groups,respectively(p¼0.3).All deaths in both groups occurred in patients who failed to achieve SDILI resolution on day 8.Conclusion:Prednisolone therapy may accelerate the recovery of SDILI.
基金Supported by the National Natural Science Foundation of China(No.51478297)Program of Introducing Talents of Discipline(No.B13011)
文摘The accelerated life test was carded out to investigate the change of spectral transmittance of di-methyl silicon oil and the effects on the electrical performance of silicon solar cell. The di-methyl silicon oil samples be- fore and after accelerated life test were analyzed by FT-IR, GC-MS and LC-MS. The ring compounds and linear compounds with larger molecular weight were detected. The spectral transmittance of di-methyl silicon oil de- creased because the chromophore and auxochrome of the products made a sunlight receive decrease on the surface of the solar celt, and resulted in the reduction of cell performance. According to the decrease of spectral transmit- tance of di-methyl silicon oil, two recovery methods were proposed. The results showed that extraction was supe- rior to vacuum distillation in recovering the aged di-methyl silicon oil.
基金Supported by the Guiding Science and Technology Planning Project of Ji an City.
文摘[Objectives]To observe the application effect of the concept of accelerated recovery after surgery(ERAS)on patients undergoing trans-urethral holmium laser enucleation of prostate(HoLEP)during perioperative period.[Methods]HoLEP patients with benign prostatic hyperplasia admitted to the Department of Urology,Affiliated Hospital of Jinggangshan University from June to December in 2022 were divided into the observation and control group.40 patients in the control group were given perioperative routine nursing,while 40 patients in the observation group were given perioperative systematic nursing under the concept of ERAS.The nursing effect of different measures were evaluated.[Results]The perioperative related indexes of patients in the observation group were lower than those in the control group(P<0.05).The postoperative feeding,exhaust,spontaneous urination,getting out of bed and hematuria stop time of patients in the observation group were all shorter than those in the control group(P<0.05).The IPSS score and RUV of patients in the observation group were significantly lower than those in the control group,while their Qmax was higher than that in the control group(P<0.05).The incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).[Conclusions]The application of perioperative systematic nursing under ERAS concept in HoLEP patients can promote patients rapid recovery and reduce their complications.
