目的:验证流调中心抑郁量表(The Center for Epidemiological Studies Depression Scale,CES-D)在我国青少年中的适用性。方法:收集10,210名13-18岁青少年被试做答的结果。结果:CES-D的Cronbach α系数为0.88;验证性因素分析支持原量表...目的:验证流调中心抑郁量表(The Center for Epidemiological Studies Depression Scale,CES-D)在我国青少年中的适用性。方法:收集10,210名13-18岁青少年被试做答的结果。结果:CES-D的Cronbach α系数为0.88;验证性因素分析支持原量表4因子的结构;性别差异显著,女生得分高于男生;年级差异显著,得分呈现随年级升高而升高的趋势;学业成绩、家庭状况等不同的被试在CES-D得分上也有显著差异。结论:CES-D在中学生群体中使用时显示出良好的信度和效度,基本适用于我国青少年。展开更多
Nonalcoholic fatty liver disease(NAFLD) has become the dominant form of chronic liver disease in children and adolescents with the increasing prevalence of obesity worldwide. NAFLD represents a wide spectrum of condit...Nonalcoholic fatty liver disease(NAFLD) has become the dominant form of chronic liver disease in children and adolescents with the increasing prevalence of obesity worldwide. NAFLD represents a wide spectrum of conditions, ranging from fatty liver-which generally follows a benign, non-progressive clinical course-to non-alcoholic steatohepatitis, a subset of NAFLD that may progress to cirrhosis and end-stage liver disease or liver carcinoma. The underlying pathophysiological mechanism of "pediatric" NAFLD remains unclear, although it is strongly associated with obesity and insulin resistance. In this review we provide a general overview on the current understanding of NAFLD in children and adolescents, which underpins practice, enabling early diagnosis and appropriate therapeutic intervention for this life-threatening liver disease.展开更多
文摘目的:验证流调中心抑郁量表(The Center for Epidemiological Studies Depression Scale,CES-D)在我国青少年中的适用性。方法:收集10,210名13-18岁青少年被试做答的结果。结果:CES-D的Cronbach α系数为0.88;验证性因素分析支持原量表4因子的结构;性别差异显著,女生得分高于男生;年级差异显著,得分呈现随年级升高而升高的趋势;学业成绩、家庭状况等不同的被试在CES-D得分上也有显著差异。结论:CES-D在中学生群体中使用时显示出良好的信度和效度,基本适用于我国青少年。
基金Supported by The National Key Research and Development Program of China,No.2016YFC1305301
文摘Nonalcoholic fatty liver disease(NAFLD) has become the dominant form of chronic liver disease in children and adolescents with the increasing prevalence of obesity worldwide. NAFLD represents a wide spectrum of conditions, ranging from fatty liver-which generally follows a benign, non-progressive clinical course-to non-alcoholic steatohepatitis, a subset of NAFLD that may progress to cirrhosis and end-stage liver disease or liver carcinoma. The underlying pathophysiological mechanism of "pediatric" NAFLD remains unclear, although it is strongly associated with obesity and insulin resistance. In this review we provide a general overview on the current understanding of NAFLD in children and adolescents, which underpins practice, enabling early diagnosis and appropriate therapeutic intervention for this life-threatening liver disease.