The wide occurrence of estrogenic compounds 4-tert-octylphenol, 4-nonylphenol, bisphenol A in surface water of Guanting Reservoir was successfully determined. The target compounds in water samples were preconcentrated...The wide occurrence of estrogenic compounds 4-tert-octylphenol, 4-nonylphenol, bisphenol A in surface water of Guanting Reservoir was successfully determined. The target compounds in water samples were preconcentrated by liquid-liquid extraction with dichloromethane, derivatized by trifluoroacetic anhydride, and quantified by gas chromatography-mass spectrometry(GC-MS) with selected ion monitoring(SIM). In the selected seven sampling sites(S1\_S7), the concentration of NP in sample S7 was significantly higher than the other in reservoir. The status of pollution in S3 and S7 were much more serious. The concentrations of OP, NP and BPA were in the range of 44.5—48.8, 221.6—349.6 and 30.2—82.7 ng/L, respectively. The pollutants were mainly inputted from the upper river and released from sediments in Guanting Reservoir.展开更多
4-tert-octylphenol (OP) is environmental pollutants that have been shown widespread impact estrogenic and toxic to the cells of mammals in culture. The effects of OP on the reproductive system of adult male vertebrate...4-tert-octylphenol (OP) is environmental pollutants that have been shown widespread impact estrogenic and toxic to the cells of mammals in culture. The effects of OP on the reproductive system of adult male vertebrates especially humans are virtually unknown. Thus, in the present investigation, pregnant females of albino rats were orally treated during pregnancy and until 21 days after birth (the period of lactation) with octylphenol (OP) at doses 0 (vehicle: corn oil), 40 mg/kg and 120 mg/kg on the epididymis of male rats at puberty (12 weeks of age). The present result showed that there is non-significant in the number;the size of newborn rats and there increased in mortality rate of newborn rats of the pregnant female treatment with dose low-and high-octylphenol compared to the control group. there is increased in the average body weight and percentage of gain in body weight of male rats from mothers of small treatment (G2, G3) and the control group (G1) for 12 weeks of age. Also, histological results showed that the adrenal gland in the group which was given high dose of octylphenol (G3) show that Severe histological changes in the cortex. When examining medulla and found large areas of necrosis and cell degradation, necrosis and cell death sharply.展开更多
为探讨辛基酚对鳞翅目模式昆虫家蚕生长发育的影响,使用添加0.01~0.08 g·kg-1辛基酚(4-tert-octylphenol,4-t-OP)的人工饲料饲养家蚕(Bombyx mori L.),研究了4-t-OP对家蚕幼虫和蛹的生长发育速度、生长量、发育整齐度和生命力等影...为探讨辛基酚对鳞翅目模式昆虫家蚕生长发育的影响,使用添加0.01~0.08 g·kg-1辛基酚(4-tert-octylphenol,4-t-OP)的人工饲料饲养家蚕(Bombyx mori L.),研究了4-t-OP对家蚕幼虫和蛹的生长发育速度、生长量、发育整齐度和生命力等影响。结果表明:连续取食0.01 g·kg-1以上浓度4-t-OP的饲料,家蚕幼虫和蛹的生长发育速度(幼虫期和蛹期发育经过时间)、生长量(幼虫期体质量和蛹期茧层量)、生命力(3龄起蚕绝食生命时数、4龄起蚕结茧率、蚕茧的死笼率和羽化率)等都明显下降,抑制眠蚕体质量。4-t-OP对家蚕幼虫生长发育后期、化蛹及羽化等发育变态期的影响更加明显,其在家蚕体内可能有累积效应。添食0.08 g·kg-14-t-OP的家蚕不能完成生活史。研究表明,4-t-OP对家蚕生长发育毒性影响有显著的浓度效应和时间效应。展开更多
In this study, we have investigated the degradation and primary radiolytic degradation mechanism of 4-tert-octylphenol (4-t-OP) by using of electron beam (EB) -irradiation. The results show that at an absorbed dose of...In this study, we have investigated the degradation and primary radiolytic degradation mechanism of 4-tert-octylphenol (4-t-OP) by using of electron beam (EB) -irradiation. The results show that at an absorbed dose of 10 kGy and an initial concentration of 25 mg·L -1 , the degradation of 4-t-OP in a methanol/water reduction system is higher than in a acetonitrile/water oxidation system by 19.4% and higher than in an acetone/water system by 26.8%, which is due to both of ·OH and e aq - playing an important role in the decomposition of 4-t-OP, although the latter is more effective. The degradation rate of 4-t-OP will decrease with increment of absorbed dose in a methanol/water solution, and increase with decrement of initial concentration at a constant absorbed dose. The degradation efficiency will also decrease with the addition of anions and H 2 O 2 into the solution. A system saturated with N 2 will make an increment in the degradation of 4-t-OP. The pH value of solution has been also found to affect the degradation efficiency, while the degradation is more efficient in alkaline conditions. Finally, the initial products involved in degradation reaction have been determined to be ethylbenzene, styrene, bicyclo[4.2.0]octa-1,3,5-triene, 2,2,4-trimethylpentane and p-tert-butyl-phenol, which may arise from e aq - attack at the position of the alkyl side chain of 4-t-OP molecule. The results have been revealed that EB irradiation is a promising method for degradation of 4-t-OP, and e aq - may be main reactive species to attack at the position of the alkyl side chain of 4-t-OP.展开更多
文摘The wide occurrence of estrogenic compounds 4-tert-octylphenol, 4-nonylphenol, bisphenol A in surface water of Guanting Reservoir was successfully determined. The target compounds in water samples were preconcentrated by liquid-liquid extraction with dichloromethane, derivatized by trifluoroacetic anhydride, and quantified by gas chromatography-mass spectrometry(GC-MS) with selected ion monitoring(SIM). In the selected seven sampling sites(S1\_S7), the concentration of NP in sample S7 was significantly higher than the other in reservoir. The status of pollution in S3 and S7 were much more serious. The concentrations of OP, NP and BPA were in the range of 44.5—48.8, 221.6—349.6 and 30.2—82.7 ng/L, respectively. The pollutants were mainly inputted from the upper river and released from sediments in Guanting Reservoir.
文摘4-tert-octylphenol (OP) is environmental pollutants that have been shown widespread impact estrogenic and toxic to the cells of mammals in culture. The effects of OP on the reproductive system of adult male vertebrates especially humans are virtually unknown. Thus, in the present investigation, pregnant females of albino rats were orally treated during pregnancy and until 21 days after birth (the period of lactation) with octylphenol (OP) at doses 0 (vehicle: corn oil), 40 mg/kg and 120 mg/kg on the epididymis of male rats at puberty (12 weeks of age). The present result showed that there is non-significant in the number;the size of newborn rats and there increased in mortality rate of newborn rats of the pregnant female treatment with dose low-and high-octylphenol compared to the control group. there is increased in the average body weight and percentage of gain in body weight of male rats from mothers of small treatment (G2, G3) and the control group (G1) for 12 weeks of age. Also, histological results showed that the adrenal gland in the group which was given high dose of octylphenol (G3) show that Severe histological changes in the cortex. When examining medulla and found large areas of necrosis and cell degradation, necrosis and cell death sharply.
基金Supported by National Natural Science Foundation of China(no.11025526,11175112 and 41073073)
文摘In this study, we have investigated the degradation and primary radiolytic degradation mechanism of 4-tert-octylphenol (4-t-OP) by using of electron beam (EB) -irradiation. The results show that at an absorbed dose of 10 kGy and an initial concentration of 25 mg·L -1 , the degradation of 4-t-OP in a methanol/water reduction system is higher than in a acetonitrile/water oxidation system by 19.4% and higher than in an acetone/water system by 26.8%, which is due to both of ·OH and e aq - playing an important role in the decomposition of 4-t-OP, although the latter is more effective. The degradation rate of 4-t-OP will decrease with increment of absorbed dose in a methanol/water solution, and increase with decrement of initial concentration at a constant absorbed dose. The degradation efficiency will also decrease with the addition of anions and H 2 O 2 into the solution. A system saturated with N 2 will make an increment in the degradation of 4-t-OP. The pH value of solution has been also found to affect the degradation efficiency, while the degradation is more efficient in alkaline conditions. Finally, the initial products involved in degradation reaction have been determined to be ethylbenzene, styrene, bicyclo[4.2.0]octa-1,3,5-triene, 2,2,4-trimethylpentane and p-tert-butyl-phenol, which may arise from e aq - attack at the position of the alkyl side chain of 4-t-OP molecule. The results have been revealed that EB irradiation is a promising method for degradation of 4-t-OP, and e aq - may be main reactive species to attack at the position of the alkyl side chain of 4-t-OP.
