Purpose:To investigate the distribution and changes in corneal four-order spherical aberration Z40 in patients with age-related cataract before and after phacoemulsification,and to direct the application of aspherical...Purpose:To investigate the distribution and changes in corneal four-order spherical aberration Z40 in patients with age-related cataract before and after phacoemulsification,and to direct the application of aspherical intraocular lens (IOL)in PHACO combined with IOL implantation.Methods:A total of 155 eyes in 93 patients with age-related cataract were included.All patients received a comprehensive ophthalmologic examination.Corneal Z40 at a pupil diameter of 6 mm was measured by using a Scheimpflug photography system (Pentacam) preoperatively and 3 months postoperatively.Results:The mean corneal Z40 before and after the PHACO at a diameter of 6 mm was(0.294 ±0.138)μm and(0.271 ± 0.130)μm,respectively,with statistical significance(P<0.05, t =4.384).There was no significant difference between male (n=45, 76 eyes) and female patients (n=48,79 eyes) regard- ing corneal Z40 (t=-0.418,P=0.676).The corneal Z40 for patients (35 eyes) aged from 50 to 59 years was (0.238±0.104) μm preoperatively;(0.308 ±0.104)μm for 60 to 69 years; (0.332±0.151)μm for 70 to 79 years; and (0.307±0.164) μm for 80 to 89 years.A significant difference in Z40 was observed among different age groups.A linear positive correlation was noted between corneal Z40 and ages (r=0.203,P<0.003). Conclusion:The corneal Z40 varied significantly among cataract patients. Patients' corneal Z40 , which should be considered when choosing aspherical IOL, increases slightly with age.Thus,customized aspheric IOLs are needed.展开更多
目的比较个性化选择0、-0.20μm、-0.27μm三种不同球差非球面人工晶状体(intraocular lens,IOL)及其随机植入术后的视觉质量,探讨最佳矫正球差值。方法前瞻性病例对照研究。选取就诊于我科的白内障患者125例(145眼),术前使用i Trace全...目的比较个性化选择0、-0.20μm、-0.27μm三种不同球差非球面人工晶状体(intraocular lens,IOL)及其随机植入术后的视觉质量,探讨最佳矫正球差值。方法前瞻性病例对照研究。选取就诊于我科的白内障患者125例(145眼),术前使用i Trace全视觉功能分析仪测量角膜高阶像差,根据角膜球差(spherical aberation,SA)值的不同分为A、B、C三组,分别植入三种不同SA非球面IOL,对照组(D组)随机植入非球面IOL。术后3个月分析全眼及角膜的高阶像差、调制传递函数(modulation transfer function,MTF)、斯泰尔比值(Strehl ratio,SR)、最佳矫正视力(best corrected visual acuity,BCVA)。结果 (1)手术前后角膜SA差异无统计学意义(P>0.05),全眼慧差(Coma)、三叶草差(Trefoil)及总高阶像差(total high order aherration,t HOA)手术前后的变化与角膜SA的变化相似。(2)三组患者BCVA差异无统计学意义(P>0.05)。(3)3 mm瞳孔直径下,四组IOL眼的角膜SA、全眼MTF t HOA及SR差异均无统计学意义(均为P>0.05);全眼SA差异有统计学意义(P=0.019),A组、B组、C组间差异无统计学意义(P>0.05),但均<D组(P=0.000)。(4)5 mm瞳孔直径下,四组IOL眼角膜SA差异无统计学意义(P>0.05);全眼SA、t HOA差异均有统计学意义(均为P=0.000),A、B、C三组间差异无统计学意义(P>0.05),但均<D组(P=0.000);全眼MTF t HOA及SR差异均有统计学意义(均为P<0.05),A、B、C三组间差异无统计学意义(P>0.05),但均>D组(P=0.000)。结论超声乳化白内障吸出术前后角膜高阶像差无差异。小瞳孔直径下,不同SA设计非球面IOL眼术后视觉质量比较无差异。大瞳孔直径下,根据术前SA个性化选择较随机植入非球面IOL眼可获得较好的视觉质量。展开更多
目的利用OPD-SCAN波前像差分析仪检查和分析近视眼患者准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后全眼和角膜前表面球面像差的改变。方法连续选取患者40例73眼进行手术前后波前像差检查,分低、中、高3个屈光度...目的利用OPD-SCAN波前像差分析仪检查和分析近视眼患者准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后全眼和角膜前表面球面像差的改变。方法连续选取患者40例73眼进行手术前后波前像差检查,分低、中、高3个屈光度组,计算出6mm瞳孔直径全眼和角膜前表面的球面像差值:(1)各组内术前、术后1周、术后3个月的球面像差比较采用单向方差分析,并用Post Hoc Tests进行两两比较;(2)术前屈光度和术后球面像差采用直线相关分析;(3)全眼和角膜前表面术后3个月球面像差较术前的变化采用t检验分析。结果低、中、高度各组术前、术后1周和术后3个月全眼和角膜前表面球面像差均方根值经比较差异有统计学意义(P<0.01)。术后1周和术后3个月的全眼和角膜前表面的球面像差均方根值均与术前屈光度(绝对值)呈正相关(P<0.01)。低、中、高度组全眼和角膜前表面术后3个月球面像差与术前球面像差的差值经比较差异有统计学意义(P<0.05)。结论LASIK术后全眼和角膜前表面的球面像差显著增加,并与术前屈光度(绝对值)呈正相关。LASIK术后全眼和角膜前表面的球面像差的增加是不同步的,以角膜前表面的球面像差增加更为显著。展开更多
文摘Purpose:To investigate the distribution and changes in corneal four-order spherical aberration Z40 in patients with age-related cataract before and after phacoemulsification,and to direct the application of aspherical intraocular lens (IOL)in PHACO combined with IOL implantation.Methods:A total of 155 eyes in 93 patients with age-related cataract were included.All patients received a comprehensive ophthalmologic examination.Corneal Z40 at a pupil diameter of 6 mm was measured by using a Scheimpflug photography system (Pentacam) preoperatively and 3 months postoperatively.Results:The mean corneal Z40 before and after the PHACO at a diameter of 6 mm was(0.294 ±0.138)μm and(0.271 ± 0.130)μm,respectively,with statistical significance(P<0.05, t =4.384).There was no significant difference between male (n=45, 76 eyes) and female patients (n=48,79 eyes) regard- ing corneal Z40 (t=-0.418,P=0.676).The corneal Z40 for patients (35 eyes) aged from 50 to 59 years was (0.238±0.104) μm preoperatively;(0.308 ±0.104)μm for 60 to 69 years; (0.332±0.151)μm for 70 to 79 years; and (0.307±0.164) μm for 80 to 89 years.A significant difference in Z40 was observed among different age groups.A linear positive correlation was noted between corneal Z40 and ages (r=0.203,P<0.003). Conclusion:The corneal Z40 varied significantly among cataract patients. Patients' corneal Z40 , which should be considered when choosing aspherical IOL, increases slightly with age.Thus,customized aspheric IOLs are needed.
文摘目的比较个性化选择0、-0.20μm、-0.27μm三种不同球差非球面人工晶状体(intraocular lens,IOL)及其随机植入术后的视觉质量,探讨最佳矫正球差值。方法前瞻性病例对照研究。选取就诊于我科的白内障患者125例(145眼),术前使用i Trace全视觉功能分析仪测量角膜高阶像差,根据角膜球差(spherical aberation,SA)值的不同分为A、B、C三组,分别植入三种不同SA非球面IOL,对照组(D组)随机植入非球面IOL。术后3个月分析全眼及角膜的高阶像差、调制传递函数(modulation transfer function,MTF)、斯泰尔比值(Strehl ratio,SR)、最佳矫正视力(best corrected visual acuity,BCVA)。结果 (1)手术前后角膜SA差异无统计学意义(P>0.05),全眼慧差(Coma)、三叶草差(Trefoil)及总高阶像差(total high order aherration,t HOA)手术前后的变化与角膜SA的变化相似。(2)三组患者BCVA差异无统计学意义(P>0.05)。(3)3 mm瞳孔直径下,四组IOL眼的角膜SA、全眼MTF t HOA及SR差异均无统计学意义(均为P>0.05);全眼SA差异有统计学意义(P=0.019),A组、B组、C组间差异无统计学意义(P>0.05),但均<D组(P=0.000)。(4)5 mm瞳孔直径下,四组IOL眼角膜SA差异无统计学意义(P>0.05);全眼SA、t HOA差异均有统计学意义(均为P=0.000),A、B、C三组间差异无统计学意义(P>0.05),但均<D组(P=0.000);全眼MTF t HOA及SR差异均有统计学意义(均为P<0.05),A、B、C三组间差异无统计学意义(P>0.05),但均>D组(P=0.000)。结论超声乳化白内障吸出术前后角膜高阶像差无差异。小瞳孔直径下,不同SA设计非球面IOL眼术后视觉质量比较无差异。大瞳孔直径下,根据术前SA个性化选择较随机植入非球面IOL眼可获得较好的视觉质量。
文摘目的利用OPD-SCAN波前像差分析仪检查和分析近视眼患者准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后全眼和角膜前表面球面像差的改变。方法连续选取患者40例73眼进行手术前后波前像差检查,分低、中、高3个屈光度组,计算出6mm瞳孔直径全眼和角膜前表面的球面像差值:(1)各组内术前、术后1周、术后3个月的球面像差比较采用单向方差分析,并用Post Hoc Tests进行两两比较;(2)术前屈光度和术后球面像差采用直线相关分析;(3)全眼和角膜前表面术后3个月球面像差较术前的变化采用t检验分析。结果低、中、高度各组术前、术后1周和术后3个月全眼和角膜前表面球面像差均方根值经比较差异有统计学意义(P<0.01)。术后1周和术后3个月的全眼和角膜前表面的球面像差均方根值均与术前屈光度(绝对值)呈正相关(P<0.01)。低、中、高度组全眼和角膜前表面术后3个月球面像差与术前球面像差的差值经比较差异有统计学意义(P<0.05)。结论LASIK术后全眼和角膜前表面的球面像差显著增加,并与术前屈光度(绝对值)呈正相关。LASIK术后全眼和角膜前表面的球面像差的增加是不同步的,以角膜前表面的球面像差增加更为显著。