The terminal alkyne was constructed in chlorin chromophore by Grignard reaction and oxidation to give chlorin 2 and 3, respectively. After deprotection the diketo chlorin 4 was obtained which was readily converted to ...The terminal alkyne was constructed in chlorin chromophore by Grignard reaction and oxidation to give chlorin 2 and 3, respectively. After deprotection the diketo chlorin 4 was obtained which was readily converted to the Zn-complex 5. Chlorin-enediyne dyads 6 fused with heterocyclic ring was synthesized by a palladium-catalyzed coupling reaction with 2-(1-hexynyl)-3-chlorothiophene.展开更多
文摘The terminal alkyne was constructed in chlorin chromophore by Grignard reaction and oxidation to give chlorin 2 and 3, respectively. After deprotection the diketo chlorin 4 was obtained which was readily converted to the Zn-complex 5. Chlorin-enediyne dyads 6 fused with heterocyclic ring was synthesized by a palladium-catalyzed coupling reaction with 2-(1-hexynyl)-3-chlorothiophene.
