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“一带一路”背景下制度距离对我国向中东和北非出口贸易影响研究 被引量:9
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作者 王晓宇 《国际商务研究》 北大核心 2020年第1期17-28,共12页
中东和北非国家是我国"一带一路"倡议的重要合作伙伴,该地区各国经济发展水平和制度环境迥异,在经济制度和政治制度方面与我国存在较大差异。基于全球治理指数和经济自由度指数相关数据,分别计算出我国与中东和北非地区24国... 中东和北非国家是我国"一带一路"倡议的重要合作伙伴,该地区各国经济发展水平和制度环境迥异,在经济制度和政治制度方面与我国存在较大差异。基于全球治理指数和经济自由度指数相关数据,分别计算出我国与中东和北非地区24国的政治制度距离和经济制度距离,并采用2007~2016年我国对该地区的出口贸易数据,借助引力模型实证分析双边制度距离对我国出口贸易的影响及出口潜力情况。结果发现,我国与中东和北非国家政治制度距离和经济制度距离均存在临界值;只有当制度距离超过临界值时才会对我国的出口贸易产生负向影响。通过贸易潜力测算发现,我国对中东和北非部分国家出口贸易潜力巨大。最后,就如何减少双边制度差异提出建议。 展开更多
关键词 制度距离 中东和北非 引力模型 货物贸易 出口潜力
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七烯甲萘醌合成过程中关键蛋白的定位分析
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作者 陈奇 张智航 +5 位作者 夏洪志 孙怡 金柯 吕雪芹 崔世修 刘龙 《食品与发酵工业》 CAS CSCD 北大核心 2023年第2期8-12,共5页
七烯甲萘醌作为维生素K 2的重要亚型,在细胞中主要存在于细胞膜上,在氧化磷酸化的过程中起到电子载体的作用。作为七烯甲萘醌合成过程中的关键酶,1,4-二羟基-2-萘甲酸异戊二烯基转移酶(1,4-dihydroxy-2-naphthoic acid prenyltransferas... 七烯甲萘醌作为维生素K 2的重要亚型,在细胞中主要存在于细胞膜上,在氧化磷酸化的过程中起到电子载体的作用。作为七烯甲萘醌合成过程中的关键酶,1,4-二羟基-2-萘甲酸异戊二烯基转移酶(1,4-dihydroxy-2-naphthoic acid prenyltransferase,MenA)和甲基转移酶(methyltransferase,MenH)目前研究较少,其在细胞中的分布还未被研究,这也限制了七烯甲萘醌产量的进一步提高。该研究重点关注MenA和MenH在细胞内的分布问题,首先构建MenA、MenH和eGFP的融合蛋白,利用荧光定位的方法确定MenA和MenH在细胞中的定位。然后,使用表面活性剂Triton-100破坏细胞膜的结构,发现随着表面活性剂浓度的增加,七烯甲萘醌的合成受到明显抑制。该研究表明细胞膜结构的完整性是七烯甲萘醌合成的前提条件,并且揭示了七烯甲萘醌是在细胞膜上直接被合成,不是被转运到细胞膜中。研究结果为深入探索七烯甲萘醌合成机制提供了方向。 展开更多
关键词 七烯甲萘醌 枯草芽孢杆菌 mena MenH 细胞膜 定位
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Comparison of WRF Model Physics Parameterizations over the MENA-CORDEX Domain 被引量:3
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作者 George Zittis Panos Hadjinicolaou Jos Lelieveld 《American Journal of Climate Change》 2014年第5期490-511,共22页
We investigated the performance of 12 different physics configurations of the climate version of the Weather, Research and Forecasting (WRF) Model over the Middle East and North Africa (MENA) domain. Possible combinat... We investigated the performance of 12 different physics configurations of the climate version of the Weather, Research and Forecasting (WRF) Model over the Middle East and North Africa (MENA) domain. Possible combinations among two Planetary Boundary Layer (PBL), three Cumulus (CUM) and two Microphysics (MIC) schemes were tested. The 2-year simulations (December 1988-November 1990) have been compared with gridded observational data and station measurements for several variables, including total precipitation and maximum and minimum 2-meter air temperature. An objective ranking method of the 12 different simulations and the selection procedure of the best performing configuration for the MENA domain are based on several statistical metrics and carried out for relevant sub-domains and individual stations. The setup for cloud microphysics is found to have the strongest impact on temperature biases while precipitation is most sensitive to the cumulus parameterization scheme and mainly in the tropics. 展开更多
关键词 WRF Physics PARAMETERIZATIONS Regional Climate Modeling Sensitivity mena CORDEX
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沙特能源转型及氢能发展展望 被引量:4
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作者 胡旭 江涵 张锐 《储能科学与技术》 CAS CSCD 北大核心 2022年第7期2354-2365,共12页
在当前世界能源结构清洁化的情况下,长期依赖石油经济的沙特阿拉伯提出能源转型和经济多元化发展目标。基于此,文章对沙特能源转型动因及发展方向进行剖析,提出氢能发展构想,并对其氢能中长期开发与国际贸易的经济性进行量化分析。调研... 在当前世界能源结构清洁化的情况下,长期依赖石油经济的沙特阿拉伯提出能源转型和经济多元化发展目标。基于此,文章对沙特能源转型动因及发展方向进行剖析,提出氢能发展构想,并对其氢能中长期开发与国际贸易的经济性进行量化分析。调研显示,在中短期内借助丰富的天然气资源优先发展蓝氢,构建产业链,后期利用丰富的清洁能源资源开发绿氢将成为沙特能源转型重要机遇。而相似国家可借鉴沙特能源结构化调整措施,实现本国的能源转型和氢能发展。 展开更多
关键词 氢能 中东北非 能源转型 可再生能源 “一带一路”
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α-萘乙酸甲酯对马铃薯贮藏期营养品质的影响及残留动态研究 被引量:5
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作者 汪河伟 贺永健 +5 位作者 刘焕 黄清怡 周雄 黄经纬 孙远明 柳春红 《食品工业科技》 CAS CSCD 北大核心 2018年第9期272-277,共6页
为研究贮藏期间α-萘乙酸甲酯(MENA)对马铃薯品质营养功能的影响及其残留动态变化,以"山东潍坊菜用马铃薯"为试材,分别用质量浓度40、80 mg/kg的MENA溶液进行喷洒处理,以清水处理作为对照,置于4℃条件下贮藏,定期(30 d)检测... 为研究贮藏期间α-萘乙酸甲酯(MENA)对马铃薯品质营养功能的影响及其残留动态变化,以"山东潍坊菜用马铃薯"为试材,分别用质量浓度40、80 mg/kg的MENA溶液进行喷洒处理,以清水处理作为对照,置于4℃条件下贮藏,定期(30 d)检测马铃薯的腐烂率、发芽率、干物质、淀粉、VC、还原糖、蛋白质、绿原酸含量及MENA残留量等品质指标。结果表明,与对照相比MENA能减低贮藏期马铃薯的腐烂率和发芽率,有利于马铃薯外观形态的保持;MENA能延缓马铃薯贮藏期间VC含量的降低(p<0.05)且使蛋白质含量升高(p<0.05),能使还原糖含量显著升高(p<0.05)并提升绿原酸水平(p<0.05);贮藏期间MENA残留未检出,提示MENA作为抑芽剂使用其残留风险较低。 展开更多
关键词 马铃薯 贮藏 Α-萘乙酸甲酯 营养品质 残留
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Extreme dependencies and spillovers between gold and stock markets:evidence from MENA countries
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作者 Walid Mensi Debasish Maitra +1 位作者 Refk Selmi Xuan Vinh Vo 《Financial Innovation》 2023年第1期1449-1475,共27页
This study addresses whether gold exhibits the function of a hedge or safe haven as often referred to in academia.It contributes to the existing literature by(i)revisiting this question for the principal stock markets... This study addresses whether gold exhibits the function of a hedge or safe haven as often referred to in academia.It contributes to the existing literature by(i)revisiting this question for the principal stock markets in the Middle East and North Africa(MENA)region and(ii)using the copula-quantile-on-quantile and conditional value at risk methods to detail the risks facing market participants provided with accurate information about various gold and stock market scenarios(i.e.,bear,normal,bull).The results provide strong evidence of quantile dependence between gold and stock returns.Positive correlations are found between MENA gold and stock markets when both are bullish.Conversely,when stock returns are bearish,gold markets show negative correlations with MENA stock markets.The risk spillover from gold to stock markets intensified during the global financial and European crises.Given the risk spillover between gold and stock markets,investors in MENA markets should be careful when considering gold as a safe haven because its effectiveness as a hedge is not the same in all MENA stock markets.Investors and portfolio managers should rebalance their portfolio compositions under various gold and stock market conditions.Overall,such precise insights about the heterogeneous linkages and spillovers between gold and MENA stock returns provide potential input for developing effective hedging strategies and optimal portfolio allocations. 展开更多
关键词 Copula CoVaR Extreme dependence GOLD mena markets Risk spillovers
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Soil organic matter amendments in date palm groves of the Middle Eastern and North African region:a mini-review 被引量:1
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作者 Rawan MLIH Roland BOL +1 位作者 Wulf AMELUNG Nadhem BRAHIM 《Journal of Arid Land》 SCIE CSCD 2016年第1期77-92,共16页
Countries in the Middle Eastern and North African (MENA) region are among the most water-scarce regions in the world, and their dryland soils are usually poor in organic carbon content (<0.5%). In this study, we su... Countries in the Middle Eastern and North African (MENA) region are among the most water-scarce regions in the world, and their dryland soils are usually poor in organic carbon content (<0.5%). In this study, we summarize examples of how people in the few oases of the MENA region overcome environmental challenges by sustainably managing economically important date production. On the basis of the limited studies found in the existing literature, this mini-review focuses on the role of traditional soil organic matter amendments beneath the soil surface as a key tool in land restoration. We conclude that soil organic matter amendments can be very successful in restoring soil water and preventing the soil from salinization. 展开更多
关键词 review Middle Eastern and North African (mena) DRYLANDS organic matter amendments oasis agrosystem date palm production
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A grey model with periodic term for sea-level analysis and its application to the Guangxi coast 被引量:1
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作者 夏华永 李树华 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1999年第3期325-335,共11页
A grey model with periodic term for sea-level analysis is presented.The present model keeps some advantages of tea GM (1, 1 )model, which well reflects the trend of sea-level changes and gives out the change rate as ... A grey model with periodic term for sea-level analysis is presented.The present model keeps some advantages of tea GM (1, 1 )model, which well reflects the trend of sea-level changes and gives out the change rate as well as the acceleration of sea level conveniently.level conveniently.In addition, the present model can reproduce the periodic phenomena of sealevel, hence, it overcomes the shortcomings of the GM(1,1) model that is unsuitable for forecasting monthly mean sealevel with apparent periodicity, and its prediction accuracy is improved.The present model is used to analyse Guangxi coast sea level,the results show that the rise rates of relative sea level at Beihai, Weizhou and Bailongwei are 1 .67,2 .51 and 0.89 mm/a respectively, the relative sea level at Shitoubu has a falling trend with a rate of 0. 5- 1 .0 mm/a, the rise rate of eustatic sea level along the Guangxi coast is 2 .0 mm/a. In comparison with the model with a lineartrend term plus a periodic term, the simulation accuracies of both models are about the same. 展开更多
关键词 Grey model periodic term monthly mena sea level maximum entropy spectral analysis
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TES通过Mena依赖的方式抑制胃癌生长和转移 被引量:3
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作者 王丹丹 陈义兵 +9 位作者 赵靖靖 张晓菲 朱广超 翁德胜 潘科 吕琳 潘求忠 江珊珊 王磊磊 夏建川 《癌症》 SCIE CAS CSCD 2020年第7期321-334,共14页
背景与目的在前期研究中,我们在原发性胃癌(gastric cancer,GC)中发现了一个候选抑癌基因——TES(testin LIM domain protein)。TES包括3个LIM结构域,后者是与细胞黏附和细胞骨架调节蛋白发生特异性相互作用的区域。Mena是一种已知的细... 背景与目的在前期研究中,我们在原发性胃癌(gastric cancer,GC)中发现了一个候选抑癌基因——TES(testin LIM domain protein)。TES包括3个LIM结构域,后者是与细胞黏附和细胞骨架调节蛋白发生特异性相互作用的区域。Mena是一种已知的细胞骨架调节因子,可通过与片状伪足(lamellipodin,Lpd)相互作用调节肌动蛋白丝的组装并调节细胞黏附与运动。因此,我们假设TES在胃癌中通过与Mena相互作用发挥抑癌因子功能。本研究旨在探索TES在胃癌中的肿瘤抑制功能。方法我们通过体外细胞增殖实验、克隆形成实验、细胞周期分析、转移实验和体内肿瘤形成与转移试验来研究TES在胃癌中的抑癌作用。采用免疫沉淀–质谱法研究TES和Mena的相互作用。我们采用免疫组化分析了172例胃癌样本中TES和Mena的表达情况,并研究了胃癌中TES和Mena的临床病理特征及预后意义。结果TES抑制胃癌细胞的增殖和克隆形成,导致细胞周期阻滞,并在裸鼠内抑制胃癌细胞的成瘤性。此外,TES还可以抑制胃癌细胞在体外的迁移和侵袭,同时抑制体内肿瘤转移。TES与Mena相互作用,抑制了Mena与Lpd之间的相互作用。Transewll实验表明,TES通过Mena依赖方式抑制胃癌细胞的迁移和侵袭。在Mena高表达的胃癌患者中,TES的表达与肿瘤浸润(P=0.005)、淋巴结转移(P=0.003)、TNM分期(P=0.003)及预后(P=0.010)相关。但在Mena低表达的胃癌患者中无以上相关性。结论我们认为TES通过Mena依赖的方式发挥抑癌作用。TES可作为一种有价值的胃癌预后标志物及潜在的治疗靶标。 展开更多
关键词 胃癌 TES 抑癌因子 mena 片状伪足
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哺乳动物肌动蛋白调节蛋白在肿瘤进展和转移中的作用
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作者 王密 《中国现代医生》 2011年第23期32-33,共2页
哺乳动物肌动蛋白调节蛋白enabled(Mena)是近年来发现的新基因,在多种肿瘤中过表达。Mena与细胞运动性和黏附性的调节相关。Mena的过表达诱导细胞膜突起和增加肿瘤细胞对基质的降解活性,增加体内癌细胞的细胞能动性,促进癌细胞的侵袭和... 哺乳动物肌动蛋白调节蛋白enabled(Mena)是近年来发现的新基因,在多种肿瘤中过表达。Mena与细胞运动性和黏附性的调节相关。Mena的过表达诱导细胞膜突起和增加肿瘤细胞对基质的降解活性,增加体内癌细胞的细胞能动性,促进癌细胞的侵袭和转移。本文对其生化结构、在正常和肿瘤组织中的表达定位以其在肿瘤发生发展中的作用研进行综述。 展开更多
关键词 mena 肿瘤 侵袭 转移
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Water Shortage in MENA Region: An Interdisciplinary Overview and a Suite of Practical Solutions
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作者 Anas Zyadin 《Journal of Water Resource and Protection》 2013年第4期49-58,共10页
The chronic water shortage in the Middle East North Africa (MENA) region is a perplexing issue, undoubtedly because various operational sectors, multi-institutions and stakeholders are inextricably interconnected. In ... The chronic water shortage in the Middle East North Africa (MENA) region is a perplexing issue, undoubtedly because various operational sectors, multi-institutions and stakeholders are inextricably interconnected. In the light of climate variability and the unprecedented population growth rate, the per capita water resources and biocapacity will continue plummeting, and the demand-gap will seriously expand. Existing water quantification agreements have been deemed inefficient to solve the problem of naturally diminishing water resources and thus require immediate re-assembling. Most scholarly endeavors, including key international organizations, NGOs, and “Think Tank” policy briefs have limitedly addressed water shortage in contexts of regional politics, mass media, and, importantly, from social psychology perspectives. Therefore, a thorough analysis and interdisciplinary approach is required to find a feasible and suitable framework of solutions and from a multi-perspective podium. A synthesis of cross-sectorial bottlenecks that are crucial to water management is presented, and a suite of practical recommendations are introduced to water authorities and governments. This study argues that in the shadow of the region’s political instability, the clash of ideologies and its repercussions, and issues of national security and sovereignty, regional cooperation on water issues remain prognostications. In this essence, governments of MENA countries are urged to develop measures to substantially increase the water supply through innovative approaches. Such measures include enhancing the capacities of water harvesting, maximizing the storage capacities of the built dams, and deploying groundwater recharge techniques. Furthermore, seawater and brackish water desalination through clean energy technologies is a contemporary solution with socio-economic and multiple benefits. Multi-billion water projects might not be suitable approach in the absence of external funding and the aforementioned hurdles. Further research i 展开更多
关键词 Water Conflicts RENEWABLE Energy mena REGION INTERDISCIPLINARY Approach
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Mena、Her-2蛋白在乳腺癌组织中的表达和意义
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作者 张青山 徐正顺 郑海燕 《陕西医学杂志》 CAS 2011年第5期613-615,633,共4页
目的:探讨乳腺癌组织中Mena和人表皮生长因子受体2(Her-2)蛋白的表达和意义。方法:采用免疫组化方法检测60例乳腺癌组织和15例正常乳腺组织中Mena和Her-2蛋白的表达,同时分析其与临床病理资料的关系。结果:Mena蛋白在乳腺癌组织中的阳... 目的:探讨乳腺癌组织中Mena和人表皮生长因子受体2(Her-2)蛋白的表达和意义。方法:采用免疫组化方法检测60例乳腺癌组织和15例正常乳腺组织中Mena和Her-2蛋白的表达,同时分析其与临床病理资料的关系。结果:Mena蛋白在乳腺癌组织中的阳性表达率为73.3%(44/60),Her-2蛋白的阳性表达率为38.3%(23/60),均明显高于在正常乳腺组织中(0.0%)的表达(P<0.05),且均与临床分期及腋淋巴结转移密切相关(P<0.05),与患者年龄、肿瘤大小、雌激素受体(ER)、孕激素受体(PR)无关(P>0.05);Mena与Her-2蛋白的表达有相关性(r=0.398,P<0.01)。结论:Mena和Her-2可能在乳腺癌细胞的浸润和转移中起重要作用;检测Mena和Her-2蛋白的表达可能对判断乳腺癌的恶性程度、浸润转移潜能及预后判断有重要参考价值。 展开更多
关键词 乳腺肿瘤/病理学 蛋白质类/代谢 受体 表皮生长因子/代谢 免疫组织化学 @mena
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The Middle East and North Africa (MENA) Oil Exporters After the Global Crisis
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作者 Naci Yllmaz Bora Selcuk 《Chinese Business Review》 2012年第7期627-638,共12页
Our research topic is about the economic situation in the Middle East and North Africa (MENA) oil exporters after the global crisis in 2008. The authors tried to find the answers to the questions such as "How bad o... Our research topic is about the economic situation in the Middle East and North Africa (MENA) oil exporters after the global crisis in 2008. The authors tried to find the answers to the questions such as "How bad or good is the situation there?" and "what is the expectation about the future of the region?" Like other countries around the world, the MENA oil exporters, comprised of Algeria, Bahrain, Iran, Iraq, Kuwait, Libya, Oman, Qatar, Saudi Arabia, Sudan, United Arab Emirates, Yemen were adversely affected by the global crisis. The MENA oil exporters are recently recovering from their recession in 2009 when the global crisis was felt intensively there. GDP in the region has grown by 3.5 percent in 2010 after a low growth of 0.7 percent in 2009. The average real GDP growth excluding Libya is projected to reach 4.9 percent in 2011. Two developments mark the outlook: the unrest in the region and the surge in global fuel and food prices. For most oil exporters, the expected increase in oil prices and production volumes will lead to higher growth in 2011 and stronger fiscal and external balances, notwithstanding recent increases in government spending. The oil exporters' combined external current account surplus is estimated to increase. The effects of the political events in Tunisia and Egypt have spread in varying degrees to the MENA oil exporters in the region, and many of these countries are responding with public spending and job-creation measures to alleviate social tensions. The social unrest also highlights the need to pursue fundamental economic reforms--social policy, fiscal management, governance, business environment, labor markets, and financial sector access to facilitate more inclusive economic growth. While the MENA countries are generally divided into two sub-regions such as "oil exporters" and "oil importers" in the economic literature, the authors will deal with only the MENA oil exporters in this work. The negative effects of the global crisis in these countries on gr 展开更多
关键词 global crisis the Middle East and North Africa mena mena oil exporters
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Linking Environmental Water Scarcity and Options for Adaptation in the MENA Region
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作者 Bachar Ibrahim Henry Mensah 《Journal of Water Resource and Protection》 2017年第4期378-392,共15页
Contamination of surface and underground water by sea level rise, surface runoff, and land use activities such as industrial and agricultural activities can lead to water scarcity. Water could be available and accessi... Contamination of surface and underground water by sea level rise, surface runoff, and land use activities such as industrial and agricultural activities can lead to water scarcity. Water could be available and accessible but not suitable for human use. In the Middle East and North Africa (MENA) region countries, the agriculture sector depends massively on water for farming activities, which consumes about 80% of the available water resources. In this context, the issue of environmental water scarcity is under highlighted, though the use of this term itself is still lacking in an international context (FAO). Meanwhile, the international goal of universal access to clean freshwater is included in global development targets (SDGs). This study provides some insights and deepens our understanding on environmental water scarcity, particularly MEN-A region countries. This review paper begins with an introduction to water scarcity and continues with a discussion of environmental issues associated with water scarcity in MENA region countries. Finally, we suggest some adaptive measures in two distinct areas such as agriculture sectors and policy makers and conclude that the lack of implementation of this particular term is hindering sustainable development in MENA region countries. 展开更多
关键词 ADAPTATION mena Climate Change WATER SCARCITY WATER Quality Environment
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中东北非电网互联与可持续发展研究 被引量:1
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作者 俞凯峰 黄磊 +3 位作者 闫涛 冯宗邦 刘武艺 Radia Sedaoui 《全球能源互联网》 CSCD 2022年第1期71-84,共14页
中东北非地区能源转型进展缓慢,加速部署太阳能、风能等可再生能源资源,推动电源、电网协同规划与项目开发融资模式创新是实现区域可持续发展的必经之路。区域电力市场缺乏顶层设计,电网消纳和调节能力不足,限制了中东北非可再生能源大... 中东北非地区能源转型进展缓慢,加速部署太阳能、风能等可再生能源资源,推动电源、电网协同规划与项目开发融资模式创新是实现区域可持续发展的必经之路。区域电力市场缺乏顶层设计,电网消纳和调节能力不足,限制了中东北非可再生能源大规模开发利用。为此,详细梳理了中东北非电源开发以及电网互联发展现状,分析总结了中东北非电源、电网规划目标,明确了区域当前电力背景下的可持续发展路径。基于当前中东北非能源现状,探讨提出“清洁开发-规模储能-海水淡化-绿色制氢-电力出口联动发展模式”,为中资电力环保企业深耕“一带一路”沿线阿拉伯国家市场,以及中国牵头建设东北亚电力市场提供借鉴和参考。 展开更多
关键词 一带一路 中东北非 电网互联 能源转型
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TES functions as a Mena-dependent tumor suppressor in gastric cancer carcinogenesis and metastasis 被引量:2
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作者 Dan-dan Wang Yi-bing Chen +9 位作者 Jing-jing Zhao Xiao-fei Zhang Guang-chao Zhu De-sheng Weng Ke Pan Lin Lv Qiu-zhong Pan Shan-shan Jiang Lei-lei Wang Jian-chuan Xia 《Cancer Communications》 SCIE 2019年第1期14-27,共14页
Background: In our previous study, we identified a candidate tumor suppressor gene, testin LIM domain protein (TES), in primary gastric cancer (GC). TES contains three LIM domains, which are specific interacting regio... Background: In our previous study, we identified a candidate tumor suppressor gene, testin LIM domain protein (TES), in primary gastric cancer (GC). TES contains three LIM domains, which are specific interacting regions for the cell adhesion and cytoskeleton regulatory proteins. Mena is a known cytoskeleton regulator that regulates the assembly of actin filaments and modulates cell adhesion and motility by interacting with Lamellipodin (Lpd). Therefore, we hypothesized that TES plays a role as tumor suppressor in GC through interacting with Mena. This study aimed to investigate the tumor suppressive functions of TES in GC. Methods: We explored the tumor suppressive effect of TES in GC by in vitro cell proliferation assay, colony formation assay, cell cycle analysis, Transwell assays, and in vivo tumorigenicity and metastasis assays. The interaction of TES and Mena was investigated through immunoprecipitation-based mass spectrometry. We also analyzed the expression of TES and Mena in 172 GC specimens using immunohistochemistry and investigated the clinicopathological and prog-nostic significance of TES and Mena in GC. Results: TES suppressed GC cell proliferation and colony formation, induced cell cycle arrest, and inhibited tumorigenicity in vitro. Additionally, it inhibited GC cell migration and invasion in vitro and suppressed metastasis in vivo. TES interacted with Mena, and inhibited the interaction of Mena with Lpd. Transwell assays suggested that TES suppressed migration and invasion of GC cells in a Mena-dependent fashion. In GC patients with high Mena expression, the expression of TES was associated with tumor infiltration (P = 0.005), lymph node metastasis (P = 0.003), TNM stage (P = 0.003), and prognosis (P = 0.010). However, no significant association was observed in GC patients with low Mena expression. Conclusions: We believe that TES functions as a Mena-dependent tumor suppressor. TES represents a valuable prog-nostic marker and potential target for GC treatment. 展开更多
关键词 Gastric cancer TES Tumor suppressor mena Lamellipodin
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Historical and Future Climatic Change Scenarios for Temperature and Rainfall for Iraq 被引量:2
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作者 Saleh Zakaria Nadhir Al-Ansari Seven Knutsson 《Journal of Civil Engineering and Architecture》 2013年第12期1574-1594,共21页
The world is facing a big challenge of climatic change, mainly due to increasing concentrations of GHGs (greenhouse gases) in the atmosphere. Many researches indicated that the climate change occurred disproportiona... The world is facing a big challenge of climatic change, mainly due to increasing concentrations of GHGs (greenhouse gases) in the atmosphere. Many researches indicated that the climate change occurred disproportionately on developing countries such as MENA (Middle East and North Africa) countries. The climatic model CGCM3.1 (T47) 2 is used in this research to explain the changes in average temperatures and the rainfall on the MENA region with special emphases on Iraq. Historical records (1900-2009) and future (2020-2099) were studied and compared; each period was divided to four sub-periods of thirty years. The results showed that the average monthly temperature for the four historical periods fluctuated between the lowest and highest value as follows: 9.2-32.9, 10.3-32.7, 9.3-32.8 and 8.6-33.9 (℃). The rainfall for historical periods kept on the same distribution during the past 109 years, and fluctuated between the lowest and highest value of 21.3 mm and 37.6 mm with an average that reached up to 26.51 mm. For the future period, the maximum average monthly temperature reached up to 37.41 (℃) during June and minimum average monthly temperature reached up to 4.24 (℃) during January. The average monthly temperature fluctuated giving a clear impression that the future portends a higher temperature. The average monthly rainfall, for the future period, fluctuated between the lowest and highest value of 12.91 mm and 20.63 mm with an average that reached 16.84 mm which represent a reduction percentage of about 36.47% relative to the historical record of rainfall for the sanae months. 展开更多
关键词 Climatic change mena climatic model CGCM3.1(T47) 2 Iraq
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欧盟对中东北非政策调整之我见
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作者 方晓 《阿拉伯世界研究》 CSSCI 2008年第1期18-24,共7页
法、德两国领导人更替后,欧洲同美国的关系恢复到伊拉克战争之前的状态,但是欧盟主要大国及欧盟本身对中东北非地区的政策仍不同于美国。2003年以来,该地区一系列事件发生后,欧盟及欧洲各大国决策者和学者对以往的政策做出评估或修改:... 法、德两国领导人更替后,欧洲同美国的关系恢复到伊拉克战争之前的状态,但是欧盟主要大国及欧盟本身对中东北非地区的政策仍不同于美国。2003年以来,该地区一系列事件发生后,欧盟及欧洲各大国决策者和学者对以往的政策做出评估或修改:比以往更强调坚持长期的经济发展政策;由下而上改变政权结构;推动中东北非国家进入国际体系;提高治理能力及保障人身安全等,从而达到"以发展促安全、以安全促发展"之目的。 展开更多
关键词 发展与安全 欧盟 中东北非
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Climate pledges versus commitment: Are policy actions of Middle-East and North African countries consistent with their emissions targets?
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作者 Hermas ABUDU Presley K.WESSEH Jr Boqiang LIN 《Advances in Climate Change Research》 SCIE CSCD 2022年第4期612-621,共10页
Carbon emission is inevitable,and changes with energy consumption and economic development,presents policy options toward sustainable development path.Currently,there is little assurance from policymakers in committin... Carbon emission is inevitable,and changes with energy consumption and economic development,presents policy options toward sustainable development path.Currently,there is little assurance from policymakers in committing to climate change pledges:taking the Middle-East and North African(MENA)region as a specific case with using 2019 as a cut-off period.We conducted an interim assessment of the Paris Agreement to ascertain whether climate actions are in tandem with emissions reduction targets.Making use of difference-in-difference technique as a quasiexperiment supported by fixed-effects and placebo treatment models,the results point to evidence of less than 1%effective CO_(2) emissions reduction as of 2019 compared to the 2015 level.The current carbon emissions reduction commitment level is far-reaching contrary to the Nationally Determined Contributions(NDCs)pledged(16.43%on average by 2030 compared to the 2015 level).The analysis suggests that achieving NDCs commitments are currently major burden on policymakers since the economic development is highly linked with nonrenewable energy consumption.Furthermore,a more comprehensive framework when accounting for all available renewable and clean energy projects shows reduction levels in the range of 30%-40%from 2020 to 2030.These results suggest that the Paris Agreement in MENA countries may be more effective from 2020,thus underscore the importance of capturing ongoing projects(involving renewable and clean energy technologies)into interim policy assessment.The shared implication is that greater efforts are demanded from the region and at country levels to further decrease emissions through the use of negative emissions technologies particularly in the electricity generation sector. 展开更多
关键词 Paris Agreement Carbon emissions reduction potential Carbon effciency:Climate change policy quasi-experiment mena climate change performance
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The Relative Deprivation Theory and Yemen's Uprising
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作者 Anahita Motazed Rad Bahman Maleki 《Sociology Study》 2013年第9期678-683,共6页
The political upheavals in the Arab world during 2011 challenged the political status quo and have irrevocably paved the way toward transformation in the Middle East and North Africa (MENA), The longstanding structu... The political upheavals in the Arab world during 2011 challenged the political status quo and have irrevocably paved the way toward transformation in the Middle East and North Africa (MENA), The longstanding structural impediments to equitable growth and social justice afflicting the Arab world came to a head through a combination of persistently poverty, high unemployment, particularly among educated youth, rampant corruption, deficit of democratic governance, and essential freedoms. Yemen is the third country of the Middle Eastern countries which turmoil sparked in. All the uprisings connote of social, political and economic discontent and frustration. The main question and issue of this paper is to answer: What conditions breed change to Yemen? The paper spotlights "relative deprivation" of Ted Robert Gurr as the most relevant theory to illustrate roots of the Yemen uprising. Relative deprivation theory holds that instead of an absolute standard deprivation, a gap between expectations and reality leads men to political violence. Therefore, this study is to utilize relative deprivation theory to explain how socio-economic shortages (such as high unemployment and education, along with poverty) and political inefficiencies of the Yemen's authoritarian regime led to public and collective discontent and upheaval. The intervened variables such as "ethnicity, race, religion, and sexuality" and international parameters have not been considered, 展开更多
关键词 Middle East and North Africa mena Yemen's upheaval deprivation theory AUTHORITARIANISM socio-economic shortages FRUSTRATION
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