The SAGA(Spt-Ada-Gcn5 acetyltransferase)complex is an evolutionarily conserved histone acetyltransferase complex that has a critical role in histone acetylation,gene expression,and various developmental processes in e...The SAGA(Spt-Ada-Gcn5 acetyltransferase)complex is an evolutionarily conserved histone acetyltransferase complex that has a critical role in histone acetylation,gene expression,and various developmental processes in eukaryotes.However,little is known about the composition and function of the SAGA complex in plants.In this study,we found that the SAGA complex in Arabidopsis thaliana contains not only conserved subunits but also four plant-specific subunits:three functionally redundant paralogs,SCSI,SCS2A,and SCS2B(SCS1/2A/2B),and a TAF-like subunit,TAFL.Mutations in SCS1/2A/2B lead to defective phenotypes similar to those caused by mutations in the genes encoding conserved SAGA subunits HAG1 and ADA2B,including delayed juvenile-to-adult phase transition,late flowering,and increased trichome density.Furthermore,we demonstrated that SCS1/2A/2B are required for the function of the SAGA complex in histone acetylation,thereby promoting the transcription of development-related genes.These results together suggest that SCS1/2A/2B are core subunits of the SAGA complex in Arabidopsis.Compared with SAGA complexes in other eukaryotes,the SAGA complexes in plants have evolved unique features that are necessary for normal growth and development.展开更多
Post-collisional potassic and ultrapotassic volcanic rocks are widely distributed across the Tibetan Plateau, and they are considered to be indicators of evolving mantle dynamics. A suite of potassic basalts younger t...Post-collisional potassic and ultrapotassic volcanic rocks are widely distributed across the Tibetan Plateau, and they are considered to be indicators of evolving mantle dynamics. A suite of potassic basalts younger than 55 Ma from the Saga area of western Tibet has been reported. The geochemical characteristics of these rocks distinguish themselves from other potassicltrapotassic volcanic rocks in Tibet, such as positive Nb, Ta, and Ti anomalies and strong enrichment in large ion lithophile elements (LILE), suggesting that phlogopite, rutile and/or sphene might have originated from the mantle source. These basalts are also characterized by a very wide range of 87Sr/86Sr ratios (0.709 043-0.711 915) and relatively high 143Nd/,44Nd ratios (0.512 426-0.512 470,εNd=-4.60 to -3.87). We propose a petrogenetic model for the Saga potassic rocks in which the lithospheric mantle source was infiltrated by a volatilerich (H2O, CO2) and low-degree silicate melt derived from the asthenosphere in the Middle to Late Proterozoic. After the initial Indo-Asian collision, Neo-Tethyan slab breakoff resulted in the partial melting of the previously metasomatized lithospheric mantle and the formation of the Saga potassic rocks. It is likely that the eruption of these volcanic rocks lasted at least 10 Ma.展开更多
Stream networks are considered important units in many environmental decision making processes. The extraction of streams using digital elevation models (DEMs) presents many advantages. However it is very sensitive to...Stream networks are considered important units in many environmental decision making processes. The extraction of streams using digital elevation models (DEMs) presents many advantages. However it is very sensitive to the uncertainty of the elevation datasets used. The main aim of this paper is to implement geostatistical simulations and assess the propagated uncertainty and map the error of location streams. First, point sampled elevations are used to fit a variogram model. Next two hundred DEM realizations are generated using conditional sequential Gaussian simulation;the stream network map is extracted for each of these realizations, and the collection of stream networks is analyzed to quantify the error propagation. At each grid cell, the probability of the occurrence of a stream and the propagated error are estimated. The more probable stream network are delineated and compared with the digital stream network derived from topographic map. The method is illustrated using a small dataset (8742 sampled elevations) for Anaguid Saharan platform. All computations are run in two free softwares: R and SAGA. R is used to fit variogram and to run sequential Gaussian simulation. SAGA is used to extract streams via RSAGA library.展开更多
This paper applies genetic simulated annealing algorithm (SAGA) to solving geometric constraint problems. This method makes full use of the advantages of SAGA and can handle under-/over- constraint problems naturally....This paper applies genetic simulated annealing algorithm (SAGA) to solving geometric constraint problems. This method makes full use of the advantages of SAGA and can handle under-/over- constraint problems naturally. It has advantages (due to its not being sensitive to the initial values) over the Newton-Raphson method, and its yielding of multiple solutions, is an advantage over other optimal methods for multi-solution constraint system. Our experiments have proved the robustness and efficiency of this method.展开更多
"Miranda Saga" is targeted as an intiation stroy. The typical general plot mode distinguishes this genre from other literary forms.Predicted on the archetypal theories, Rui Yuping summarizes the plot mode of..."Miranda Saga" is targeted as an intiation stroy. The typical general plot mode distinguishes this genre from other literary forms.Predicted on the archetypal theories, Rui Yuping summarizes the plot mode of initiation stories as follows: innocence -disillusionment -epiphany, which has been successfully applied to some classic novels, such as Mark Twain's Adventures of Huckleberry Finn and J.D.Salinger's The Catcher in the Rye, etc. Porter's "Miranda Saga" follows this general mode thus demonstrating it as a good illustration ofinitiation stories. In the first place, it extends the application and content of initiation stories. In the second place, it provides a new point of view for the study of Porter.展开更多
After the title was "Harry Potter era" magical masterpiece,"Lord of the Rings","Harry Potter" and;"he Chronicles of Narnia" " Twilight of the City" Series on behalf of...After the title was "Harry Potter era" magical masterpiece,"Lord of the Rings","Harry Potter" and;"he Chronicles of Narnia" " Twilight of the City" Series on behalf of the international magic series.The "Twilight of the City" series are sold in the United States had more than 50 million.And the movie is also popular in the world.The hero,Edward Cullen,is popular in the world,many comments come to this character,to understand the movie more clearly,this paper will analysis the hero,Edward Cullen,from the application of cooperative principle,finding out the conflict in his heart.展开更多
基金the National Natural Science Foundation of China(32025003)the National Key Research and Development Program of China(2016YFA0500801)from the Chinese Ministry of Science and Technology.
文摘The SAGA(Spt-Ada-Gcn5 acetyltransferase)complex is an evolutionarily conserved histone acetyltransferase complex that has a critical role in histone acetylation,gene expression,and various developmental processes in eukaryotes.However,little is known about the composition and function of the SAGA complex in plants.In this study,we found that the SAGA complex in Arabidopsis thaliana contains not only conserved subunits but also four plant-specific subunits:three functionally redundant paralogs,SCSI,SCS2A,and SCS2B(SCS1/2A/2B),and a TAF-like subunit,TAFL.Mutations in SCS1/2A/2B lead to defective phenotypes similar to those caused by mutations in the genes encoding conserved SAGA subunits HAG1 and ADA2B,including delayed juvenile-to-adult phase transition,late flowering,and increased trichome density.Furthermore,we demonstrated that SCS1/2A/2B are required for the function of the SAGA complex in histone acetylation,thereby promoting the transcription of development-related genes.These results together suggest that SCS1/2A/2B are core subunits of the SAGA complex in Arabidopsis.Compared with SAGA complexes in other eukaryotes,the SAGA complexes in plants have evolved unique features that are necessary for normal growth and development.
基金supported by the Ministry of Science and Technology of China (No 2014DFR21270)China Geological Survey (Nos. DD20160023-01, DD20160022-01)the National Natural Science Foundation of China (Nos. 41720104009, 41672063, 41773029)
文摘Post-collisional potassic and ultrapotassic volcanic rocks are widely distributed across the Tibetan Plateau, and they are considered to be indicators of evolving mantle dynamics. A suite of potassic basalts younger than 55 Ma from the Saga area of western Tibet has been reported. The geochemical characteristics of these rocks distinguish themselves from other potassicltrapotassic volcanic rocks in Tibet, such as positive Nb, Ta, and Ti anomalies and strong enrichment in large ion lithophile elements (LILE), suggesting that phlogopite, rutile and/or sphene might have originated from the mantle source. These basalts are also characterized by a very wide range of 87Sr/86Sr ratios (0.709 043-0.711 915) and relatively high 143Nd/,44Nd ratios (0.512 426-0.512 470,εNd=-4.60 to -3.87). We propose a petrogenetic model for the Saga potassic rocks in which the lithospheric mantle source was infiltrated by a volatilerich (H2O, CO2) and low-degree silicate melt derived from the asthenosphere in the Middle to Late Proterozoic. After the initial Indo-Asian collision, Neo-Tethyan slab breakoff resulted in the partial melting of the previously metasomatized lithospheric mantle and the formation of the Saga potassic rocks. It is likely that the eruption of these volcanic rocks lasted at least 10 Ma.
文摘Stream networks are considered important units in many environmental decision making processes. The extraction of streams using digital elevation models (DEMs) presents many advantages. However it is very sensitive to the uncertainty of the elevation datasets used. The main aim of this paper is to implement geostatistical simulations and assess the propagated uncertainty and map the error of location streams. First, point sampled elevations are used to fit a variogram model. Next two hundred DEM realizations are generated using conditional sequential Gaussian simulation;the stream network map is extracted for each of these realizations, and the collection of stream networks is analyzed to quantify the error propagation. At each grid cell, the probability of the occurrence of a stream and the propagated error are estimated. The more probable stream network are delineated and compared with the digital stream network derived from topographic map. The method is illustrated using a small dataset (8742 sampled elevations) for Anaguid Saharan platform. All computations are run in two free softwares: R and SAGA. R is used to fit variogram and to run sequential Gaussian simulation. SAGA is used to extract streams via RSAGA library.
文摘This paper applies genetic simulated annealing algorithm (SAGA) to solving geometric constraint problems. This method makes full use of the advantages of SAGA and can handle under-/over- constraint problems naturally. It has advantages (due to its not being sensitive to the initial values) over the Newton-Raphson method, and its yielding of multiple solutions, is an advantage over other optimal methods for multi-solution constraint system. Our experiments have proved the robustness and efficiency of this method.
文摘"Miranda Saga" is targeted as an intiation stroy. The typical general plot mode distinguishes this genre from other literary forms.Predicted on the archetypal theories, Rui Yuping summarizes the plot mode of initiation stories as follows: innocence -disillusionment -epiphany, which has been successfully applied to some classic novels, such as Mark Twain's Adventures of Huckleberry Finn and J.D.Salinger's The Catcher in the Rye, etc. Porter's "Miranda Saga" follows this general mode thus demonstrating it as a good illustration ofinitiation stories. In the first place, it extends the application and content of initiation stories. In the second place, it provides a new point of view for the study of Porter.
文摘After the title was "Harry Potter era" magical masterpiece,"Lord of the Rings","Harry Potter" and;"he Chronicles of Narnia" " Twilight of the City" Series on behalf of the international magic series.The "Twilight of the City" series are sold in the United States had more than 50 million.And the movie is also popular in the world.The hero,Edward Cullen,is popular in the world,many comments come to this character,to understand the movie more clearly,this paper will analysis the hero,Edward Cullen,from the application of cooperative principle,finding out the conflict in his heart.
