目的观察角膜胶原交联加固联合准分子激光原位角膜磨镶术(laser-assisted in situ keratomileusis,LASIK)矫正屈光不正的疗效。方法选取在我院行LASIK的患者为研究对象,其中行角膜胶原交联加固术联合LASIK治疗(治疗组)50例(100眼),行单...目的观察角膜胶原交联加固联合准分子激光原位角膜磨镶术(laser-assisted in situ keratomileusis,LASIK)矫正屈光不正的疗效。方法选取在我院行LASIK的患者为研究对象,其中行角膜胶原交联加固术联合LASIK治疗(治疗组)50例(100眼),行单纯LASIK治疗(对照组)50例(100眼),术后1周、1个月、3个月、6个月、12个月随访,对手术前后视力、屈光度、角膜内皮细胞计数、角膜透明度及术后角膜胶原交联线等进行研究。结果两组裸眼视力均≥术前最佳矫正视力。术后各时间点屈光度治疗组与对照组比较差异均有统计学意义(均为P<0.05);治疗组术后12个月与术后1个月屈光度比较差异无统计学意义(t=0.021,P=0.070),对照组术后12个月与术后1个月比较差异有统计学意义(t=4.857,P=0.010)。治疗组术后各时间点角膜内皮细胞计数与术前比较差异无统计学意义(F=1.163,P=0.327)。治疗组术后早期均发生了角膜前基质轻度混浊。术后1个月治疗组角膜胶原交联线厚度为210.00~340.00(270.48±37.80)μm,约占角膜中央厚度的63%。治疗组均未发生与角膜瓣相关的并发症,对照组出现角膜瓣皱褶者3眼,角膜瓣移位者1眼。结论角膜胶原交联加固术联合LASIK矫正屈光不正可以获得良好的术后裸眼视力,屈光度稳定,无角膜内皮细胞的丢失,术后早期出现角膜前基质轻度混浊均不响患者视力,术后效果好。展开更多
AIM：To assess the safety,efficacy,predictability and stability of implantable collamer lens（ICL） for residual refractive error after corneal refractive surgery.METHODS： This study evaluated 19 eyes of 12 patients ...AIM：To assess the safety,efficacy,predictability and stability of implantable collamer lens（ICL） for residual refractive error after corneal refractive surgery.METHODS： This study evaluated 19 eyes of 12 patients who underwent ICL implantation after corneal refractive surgeries.They were followed up for 1y to 5y of uncorrected distance visual acuity（UDVA）,corrected distance visual acuity（CDVA）,manifest refractive error,flat and steep K value,axial length,intraocular pressure,corneal endothelial cell density,adverse events after ICL surgery.RESULTS： The mean follow-up period was 39.05 ±19.22 mo（range,1-5y）.Spherical equivalent refractive error changed from-7.45±3.02 D preoperatively to-0.85±1.10 D 1wk to 1mo after ICL implantation,with the safety and efficacy indices being 1.12 and 1.15,respectively.A total of 52.63% of eyes were within ±0.5 D of the predicted spherical equivalents,73.68% were within ±1.0 D.A trend of mild regression towards myopia with axial elongation after 5y was observed.One eye with mild anterior capsule opacity and retinal detachment 1y after surgery were observed.CONCLUSION： ICL implantation is safe and effective for the correction of residual refractive error after corneal refractive surgeries,especially in moderate to high residual myopia.展开更多
目的研究分析高度近视患者准分子激光原位角膜磨镶术(laser-assisted in situ keratomileusis,LASIK)后屈光回退的危险因素,为临床预防高度近视患者LASIK术后屈光回退提供指导意见。方法选择2017年7月至2019年1月于我院眼科接受LASIK手...目的研究分析高度近视患者准分子激光原位角膜磨镶术(laser-assisted in situ keratomileusis,LASIK)后屈光回退的危险因素,为临床预防高度近视患者LASIK术后屈光回退提供指导意见。方法选择2017年7月至2019年1月于我院眼科接受LASIK手术治疗的200例高度近视患者的临床资料进行回顾性研究,根据患者LASIK术后随访1年是否发生屈光回退,将患者分为屈光回退组与对照组。分析比较两组患者的临床资料,对导致高度近视患者LASIK术后屈光回退的危险因素进行单因素分析、多因素Logistics回归分析。结果在单因素分析中,屈光回退组与对照组在年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化方面比较,差异具有统计学意义(P<0.05),而屈光回退组与对照组在性别、病程、术后瞳孔变化、术后眼压变化方面比较,差异无统计学意义(P>0.05)。经多因素Logistics回归分析,年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化为高度近视患者LASIK术后屈光回退的危险因素(P<0.05)。结论年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化是导致高度近视患者LASIK术后发生屈光回退的危险因素,临床应根据LASIK术后屈光回退危险因素采取针对性预防干预。展开更多
We report on the impact of direct ultraviolet germicidal irradiation（UVGI）on reflective optics,used in the excimer laser system Allegretto Eye-Q.The aim of our work was to confirm our hypothesis based on long-rate o...We report on the impact of direct ultraviolet germicidal irradiation（UVGI）on reflective optics,used in the excimer laser system Allegretto Eye-Q.The aim of our work was to confirm our hypothesis based on long-rate observations of obtained anomalies in post-operative results that are attributed to degradation of reflective optics upon ultraviolet radiation.The presence of direct UVGI coupled with humidity in the operating environment caused merging anomalies and unwanted post-operative correction values.Ultraviolet-A radiation caused a similar effect on the reflective cover of the mirrors.展开更多
文摘目的观察角膜胶原交联加固联合准分子激光原位角膜磨镶术(laser-assisted in situ keratomileusis,LASIK)矫正屈光不正的疗效。方法选取在我院行LASIK的患者为研究对象,其中行角膜胶原交联加固术联合LASIK治疗(治疗组)50例(100眼),行单纯LASIK治疗(对照组)50例(100眼),术后1周、1个月、3个月、6个月、12个月随访,对手术前后视力、屈光度、角膜内皮细胞计数、角膜透明度及术后角膜胶原交联线等进行研究。结果两组裸眼视力均≥术前最佳矫正视力。术后各时间点屈光度治疗组与对照组比较差异均有统计学意义(均为P<0.05);治疗组术后12个月与术后1个月屈光度比较差异无统计学意义(t=0.021,P=0.070),对照组术后12个月与术后1个月比较差异有统计学意义(t=4.857,P=0.010)。治疗组术后各时间点角膜内皮细胞计数与术前比较差异无统计学意义(F=1.163,P=0.327)。治疗组术后早期均发生了角膜前基质轻度混浊。术后1个月治疗组角膜胶原交联线厚度为210.00~340.00(270.48±37.80)μm,约占角膜中央厚度的63%。治疗组均未发生与角膜瓣相关的并发症,对照组出现角膜瓣皱褶者3眼,角膜瓣移位者1眼。结论角膜胶原交联加固术联合LASIK矫正屈光不正可以获得良好的术后裸眼视力,屈光度稳定,无角膜内皮细胞的丢失,术后早期出现角膜前基质轻度混浊均不响患者视力,术后效果好。
基金Supported by the Committee of Science and Technology of Shanghai,China(No.09411962100)the Health and Family Planning Committee of Pudong New District of Shanghai,China(No.PW2014D-1)
文摘AIM：To assess the safety,efficacy,predictability and stability of implantable collamer lens（ICL） for residual refractive error after corneal refractive surgery.METHODS： This study evaluated 19 eyes of 12 patients who underwent ICL implantation after corneal refractive surgeries.They were followed up for 1y to 5y of uncorrected distance visual acuity（UDVA）,corrected distance visual acuity（CDVA）,manifest refractive error,flat and steep K value,axial length,intraocular pressure,corneal endothelial cell density,adverse events after ICL surgery.RESULTS： The mean follow-up period was 39.05 ±19.22 mo（range,1-5y）.Spherical equivalent refractive error changed from-7.45±3.02 D preoperatively to-0.85±1.10 D 1wk to 1mo after ICL implantation,with the safety and efficacy indices being 1.12 and 1.15,respectively.A total of 52.63% of eyes were within ±0.5 D of the predicted spherical equivalents,73.68% were within ±1.0 D.A trend of mild regression towards myopia with axial elongation after 5y was observed.One eye with mild anterior capsule opacity and retinal detachment 1y after surgery were observed.CONCLUSION： ICL implantation is safe and effective for the correction of residual refractive error after corneal refractive surgeries,especially in moderate to high residual myopia.
文摘目的研究分析高度近视患者准分子激光原位角膜磨镶术(laser-assisted in situ keratomileusis,LASIK)后屈光回退的危险因素,为临床预防高度近视患者LASIK术后屈光回退提供指导意见。方法选择2017年7月至2019年1月于我院眼科接受LASIK手术治疗的200例高度近视患者的临床资料进行回顾性研究,根据患者LASIK术后随访1年是否发生屈光回退,将患者分为屈光回退组与对照组。分析比较两组患者的临床资料,对导致高度近视患者LASIK术后屈光回退的危险因素进行单因素分析、多因素Logistics回归分析。结果在单因素分析中,屈光回退组与对照组在年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化方面比较,差异具有统计学意义(P<0.05),而屈光回退组与对照组在性别、病程、术后瞳孔变化、术后眼压变化方面比较,差异无统计学意义(P>0.05)。经多因素Logistics回归分析,年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化为高度近视患者LASIK术后屈光回退的危险因素(P<0.05)。结论年龄、术前眼轴长度、术前屈光度数、术后角膜中央厚度变化是导致高度近视患者LASIK术后发生屈光回退的危险因素,临床应根据LASIK术后屈光回退危险因素采取针对性预防干预。
文摘We report on the impact of direct ultraviolet germicidal irradiation（UVGI）on reflective optics,used in the excimer laser system Allegretto Eye-Q.The aim of our work was to confirm our hypothesis based on long-rate observations of obtained anomalies in post-operative results that are attributed to degradation of reflective optics upon ultraviolet radiation.The presence of direct UVGI coupled with humidity in the operating environment caused merging anomalies and unwanted post-operative correction values.Ultraviolet-A radiation caused a similar effect on the reflective cover of the mirrors.
