摘要
目的探讨飞秒制瓣LASIK(FS-LASIK)及前弹力层下激光角膜磨镶术(SBK)对角膜后表面高度的影响。方法回顾性系列病例研究。选择同期行近视及近视散光矫正患者85例(170只眼),其中飞秒制瓣LASIK组46例(92只眼),SBK组39例(78只眼),再按等效球镜分为中低度近视组和高度近视组。分别于术前、术后1周、1个月和3个月对患者行Oculyzer眼前节分析系统检查,测量角膜顶点、角膜最薄点和以顶点为圆心2 mm(中央区)、4 mm(近周边区)及6 mm(远周边区)直径上总共26个点的角膜后表面高度。分析比较两种手术方式下中低度及高度近视患者术后各个时间点角膜后表面高度的变化。数据采用重复测量方差分析。结果术后1周、1个月、3个月时四组角膜后表面高度变化趋势基本一致,角膜顶点、最薄点及中央区轻度后移,近周边区及远周边区轻度前凸。术后各时间点及各观察部位四组的角膜后表面高度差值比较均无统计学意义(P>0.05)。结论飞秒制瓣LASIK和SBK术对中低度及高度近视角膜后表面高度的影响均较小,其总体趋势为中央区轻微后移,周边区轻度前凸。
Objective To investigate the changes in posterior corneal surface elevation after femtosecond laser-assisted in situ keratomileusis（ FS-LASIK） versus sub-Bowmans keratomileusis（ SBK）. Methods Retrospective case series study. One hundred and seventy eyes of 85 patients who underwent LASIK for correction of myopia or myopic astigmatism were divided into FS-LASIK group（46 cases of 92 eyes） and SBK group（39 cases of 78 eyes）. Based on preoperative spherical equivalent,patients were further divided into moderate or low myopia group and high myopia group. All patients were examined by Oculyzer before surgery and at 1 week,1 month and 3 months after surgery. Posterior corneal elevation was measured at totally 26 corneal points,including corneal apex,corneal thinnest point,and points on concentric circles of 2 mm,4 mm,and 6 mm for central,near peripheral and far peripheral zones,respectively. We analyzed and compared the changes in posterior corneal elevation at different time points in patients with moderate or low myopia and high myopia after two surgical procedures. The results were analyzed with repeated measures ANOVA analysis using SPSS 16. 0 software. Results At postoperative 1 week,1 month and 3 months,the four groups showed generally consistent changing trends in posterior corneal elevation; corneal vertex,thinnest corneal point and central area slightly moved backwards,while the near and far peripheral areas slightly protruded forwards. At different postoperative time points and different corneal zones,there was no statistically significant difference in posterior corneal elevation among the four groups（ P 0. 05）. Conclusions After FS-LASIK and SBK,the changes in posterior corneal elevation in moderate or low myopia groups and high myopia groups were small. The changing trends were slightly backwards displacement of the central zone and forwards protrusion of peripheral zones.
作者
王亚茹
周艳峰
Wang Yaru;Zhou Yanfeng(Department of Ophtalmology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, Chin)
出处
《临床眼科杂志》
2018年第2期116-120,共5页
Journal of Clinical Ophthalmology
