Background:To compare the safety and efficacy of LVIS stent-assisted coiling with those of laser-cut stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms.Methods:Patients wit...Background:To compare the safety and efficacy of LVIS stent-assisted coiling with those of laser-cut stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms.Methods:Patients with acutely ruptured wide-necked intracranial aneurysms treated with LVIS stent-assisted coiling(LVIS stent group)and laser-cut stent-assisted coiling(laser-cut stent group)were retrospectively reviewed from January 2014 to December 2017.Propensity score matching was used to adjust for potential differences in age,sex,aneurysm location,aneurysm size,neck width,Hunt-Hess grade,and modified Fisher grade.Perioperative procedure-related complications and clinical and angiographic follow-up outcomes were compared.Univariate and multivariate analyses were performed to determine the associations between procedure-related complications and potential risk factors.Results:A total of 142 patients who underwent LVIS stent-assisted coiling and 93 patients who underwent laser-cut stent-assisted coiling were enrolled after 1:2 propensity score matching.The angiographic follow-up outcomes showed that the LVIS stent group had a slightly higher complete occlusion rate and lower recurrence rate than the laser-cut stent group(92.7%vs 80.6%;3.7%vs 9.7%,P=0.078).The clinical outcomes at discharge and follow-up between the two groups demonstrated no significant differences(P=0.495 and P=0.875,respectively).The rates of intraprocedural thrombosis,postprocedural thrombosis,postoperative early rebleeding,and procedure-related death were 0.7%(1/142),1.4%(2/142),2.8%(4/142),and 2.1%(3/142)in the LVIS stent group,respectively,and 4.3%(4/93),2.2%(2/93),1.1%(1/93),and 3.2%(3/93)in the laser-cut stent group,respectively(P=0.082,0.649,0.651,and 0.683).Nevertheless,the rates of overall procedure-related complications and intraprocedural rupture in the LVIS stent group were significantly lower than those in the laser-cut stent group(5.6%vs 14.0%,P=0.028;0.7%vs 6.5%,P=0.016).Multivariate analysis showed that laser-cut stent-assisted coil展开更多
This study deals with Nd：YAG laser cutting nonmetallic materials, which is one of the most important and popular industrial applications of laser. The main theme is to evaluate the effects of Nd：YAG laser beam power...This study deals with Nd：YAG laser cutting nonmetallic materials, which is one of the most important and popular industrial applications of laser. The main theme is to evaluate the effects of Nd：YAG laser beam power besides work piece scanning speed. For approximate cutting depth, a theoretical study is conducted in terms of material property and cutting speed. Results show a nonlinear relation between the cutting depth and input energy. There is no significant effect of speed on cutting depth with the speed being larger than 30 mm/s. An extra energy is utilized in the deep cutting. It is inferred that as the laser power increases, cutting depth increases. The experimental outcomes are in good agreement with theoretical results. This analysis will provide a guideline for laser-based industry to select a suitable laser for cutting, scribing, trimming, engraving, and marking nonmetallic materials.展开更多
基金This work was supported by the National Key Research and Development Program of China(grant no.: 2016YFC1300703)National Natural Science Foundation of China(grant no.: 81701136, 81571126).
文摘Background:To compare the safety and efficacy of LVIS stent-assisted coiling with those of laser-cut stent-assisted coiling for the treatment of acutely ruptured wide-necked intracranial aneurysms.Methods:Patients with acutely ruptured wide-necked intracranial aneurysms treated with LVIS stent-assisted coiling(LVIS stent group)and laser-cut stent-assisted coiling(laser-cut stent group)were retrospectively reviewed from January 2014 to December 2017.Propensity score matching was used to adjust for potential differences in age,sex,aneurysm location,aneurysm size,neck width,Hunt-Hess grade,and modified Fisher grade.Perioperative procedure-related complications and clinical and angiographic follow-up outcomes were compared.Univariate and multivariate analyses were performed to determine the associations between procedure-related complications and potential risk factors.Results:A total of 142 patients who underwent LVIS stent-assisted coiling and 93 patients who underwent laser-cut stent-assisted coiling were enrolled after 1:2 propensity score matching.The angiographic follow-up outcomes showed that the LVIS stent group had a slightly higher complete occlusion rate and lower recurrence rate than the laser-cut stent group(92.7%vs 80.6%;3.7%vs 9.7%,P=0.078).The clinical outcomes at discharge and follow-up between the two groups demonstrated no significant differences(P=0.495 and P=0.875,respectively).The rates of intraprocedural thrombosis,postprocedural thrombosis,postoperative early rebleeding,and procedure-related death were 0.7%(1/142),1.4%(2/142),2.8%(4/142),and 2.1%(3/142)in the LVIS stent group,respectively,and 4.3%(4/93),2.2%(2/93),1.1%(1/93),and 3.2%(3/93)in the laser-cut stent group,respectively(P=0.082,0.649,0.651,and 0.683).Nevertheless,the rates of overall procedure-related complications and intraprocedural rupture in the LVIS stent group were significantly lower than those in the laser-cut stent group(5.6%vs 14.0%,P=0.028;0.7%vs 6.5%,P=0.016).Multivariate analysis showed that laser-cut stent-assisted coil
基金supported by the Science Foundation of the Ministry of Science and Technology Malaysiathe Islamic Development Bank Jeddahsupport of the Universiti Teknologi Malaysia for this research work
文摘This study deals with Nd：YAG laser cutting nonmetallic materials, which is one of the most important and popular industrial applications of laser. The main theme is to evaluate the effects of Nd：YAG laser beam power besides work piece scanning speed. For approximate cutting depth, a theoretical study is conducted in terms of material property and cutting speed. Results show a nonlinear relation between the cutting depth and input energy. There is no significant effect of speed on cutting depth with the speed being larger than 30 mm/s. An extra energy is utilized in the deep cutting. It is inferred that as the laser power increases, cutting depth increases. The experimental outcomes are in good agreement with theoretical results. This analysis will provide a guideline for laser-based industry to select a suitable laser for cutting, scribing, trimming, engraving, and marking nonmetallic materials.
