Phospholipids, including phosphatidic acid （PA）, phosphatidylcholine （PC）, phosphatidylethanolamine （PE）, phosphatidylglycerol （PC）, phosphatidylserine （PS） and phosphoinositides, have emerged as an importan...Phospholipids, including phosphatidic acid （PA）, phosphatidylcholine （PC）, phosphatidylethanolamine （PE）, phosphatidylglycerol （PC）, phosphatidylserine （PS） and phosphoinositides, have emerged as an important class of cellular messenger molecules in various cellular and physiological processes, of which PA attracts much attention of researchers. In addition to its effect on stimulating vesicle trafficking, many studies have demonstrated that PA plays a crucial role in various signaling pathways by binding target proteins and regulating their activity and subcellular localization. Here, we summarize the functional mechanisms and target proteins underlying PA-mediated regulation of cellular signaling, development, hormonal responses, and stress responses in plants.展开更多
The Sichuan–Tibet railway construction has received significant attention from both China and abroad.The new section from Ya’an to Nyingchi is about 1018.6 km long,including 69 tunnels with a total length of 841.7 k...The Sichuan–Tibet railway construction has received significant attention from both China and abroad.The new section from Ya’an to Nyingchi is about 1018.6 km long,including 69 tunnels with a total length of 841.7 km.The longest tunnel(Yigong tunnel)is 42.4 km long.The successful construction of the Sichuan–Tibet railway depends largely on tunnel construction.Due to the complex conditions,tunnel construction for the Sichuan–Tibet railway poses great challenges to the research community.This paper aims to illustrate the necessity of interdisciplinary and joint research to solve problems associated with tunnel construction that will be encountered in the immediate future and facilitate the communication and exchange of ideas between disciplines.To this end,based on a systematic analysis of the available data related to Sichuan–Tibet railway tunnels,six major aspects of the geology,environment,and engineering conditions are identified.Next,based on the engineering responses from the Sichuan–Tibet railway tunnels,potential technical problems and risk characteristics are predicted and evaluated.Further,six key scientific issues are identified and discussed based on a coupled multi-layer analysis of essential tunnel engineering issues.Finally,research directions,technical ideas,and research methods that should be carried out for this project are proposed.展开更多
基金supported by the National Natural Science Foundation of China(31721001 and 31400261)the“Ten Thousand Talent Program”Collaborative Innovation Center of Crop Stress Biology,Henan Province
文摘Phospholipids, including phosphatidic acid （PA）, phosphatidylcholine （PC）, phosphatidylethanolamine （PE）, phosphatidylglycerol （PC）, phosphatidylserine （PS） and phosphoinositides, have emerged as an important class of cellular messenger molecules in various cellular and physiological processes, of which PA attracts much attention of researchers. In addition to its effect on stimulating vesicle trafficking, many studies have demonstrated that PA plays a crucial role in various signaling pathways by binding target proteins and regulating their activity and subcellular localization. Here, we summarize the functional mechanisms and target proteins underlying PA-mediated regulation of cellular signaling, development, hormonal responses, and stress responses in plants.
基金the financial support by the National Natural Science of China(Grant No.51738002)the National Key R&D Program of China(Grant No.2017YFC0805401).
文摘The Sichuan–Tibet railway construction has received significant attention from both China and abroad.The new section from Ya’an to Nyingchi is about 1018.6 km long,including 69 tunnels with a total length of 841.7 km.The longest tunnel(Yigong tunnel)is 42.4 km long.The successful construction of the Sichuan–Tibet railway depends largely on tunnel construction.Due to the complex conditions,tunnel construction for the Sichuan–Tibet railway poses great challenges to the research community.This paper aims to illustrate the necessity of interdisciplinary and joint research to solve problems associated with tunnel construction that will be encountered in the immediate future and facilitate the communication and exchange of ideas between disciplines.To this end,based on a systematic analysis of the available data related to Sichuan–Tibet railway tunnels,six major aspects of the geology,environment,and engineering conditions are identified.Next,based on the engineering responses from the Sichuan–Tibet railway tunnels,potential technical problems and risk characteristics are predicted and evaluated.Further,six key scientific issues are identified and discussed based on a coupled multi-layer analysis of essential tunnel engineering issues.Finally,research directions,technical ideas,and research methods that should be carried out for this project are proposed.
