本研究通过改性红外染料和热引发剂的延迟自由基生成技术,旨在提高计算机直接制版(computer to plate,CTP)技术中免处理版的清晰度和反应性。研究提出了一种延迟自由基生成的策略,实现精确聚合,提升版材图像质量。结果表明,该技术通过...本研究通过改性红外染料和热引发剂的延迟自由基生成技术,旨在提高计算机直接制版(computer to plate,CTP)技术中免处理版的清晰度和反应性。研究提出了一种延迟自由基生成的策略,实现精确聚合,提升版材图像质量。结果表明,该技术通过自由基生成的双峰值曲线,显著提高了版材的清晰度和耐印性。此外,该技术降低了对传统化学品的依赖,减少了环境污染。总体而言,本研究为促进CTP技术的可持续发展提供了新的方法。展开更多
Photodynamic therapy(PDT) has shown promise as an effective treatment modality for cancer and other localized diseases due to its noninvasive properties and spatiotemporal selectivity. Near-infrared(NIR)fluorescent dy...Photodynamic therapy(PDT) has shown promise as an effective treatment modality for cancer and other localized diseases due to its noninvasive properties and spatiotemporal selectivity. Near-infrared(NIR)fluorescent dyes based on organic small molecules are characterized with low cytotoxicity, good biocompatibility and excellent phototoxicity, which are widely used in PDT. In this review, we attempt to summarize the development of imaging-induced PDT based on organic small molecules and classify it according to the structures of dyes including cyanines, 4,4-difluoro-4-bora-3 a,4 a-diaza-s-indacene(BODIPY) analogues, phthalocyanine and other agents such as rhodamine analogues.展开更多
Near-infrared(NIR)fluorescent dyes based on small organic molecules are characterized with low cytotoxicity,good biocompatibility and minimum interference from auto-fluorescence background,which are widely used in tum...Near-infrared(NIR)fluorescent dyes based on small organic molecules are characterized with low cytotoxicity,good biocompatibility and minimum interference from auto-fluorescence background,which are widely used in tumor diagnosis.Intensive research on molecular properties and photothermal properties of fluorescent dyes have been explored for non-invasive photothermal treatment of cancer.In this review,we focus on the development of imaging-induced photothermal therapy of small molecules and classification according to the structures of organic molecules including cyanines,phthalocyanines,rhodamine analogues and BODIPYs.展开更多
文摘本研究通过改性红外染料和热引发剂的延迟自由基生成技术,旨在提高计算机直接制版(computer to plate,CTP)技术中免处理版的清晰度和反应性。研究提出了一种延迟自由基生成的策略,实现精确聚合,提升版材图像质量。结果表明,该技术通过自由基生成的双峰值曲线,显著提高了版材的清晰度和耐印性。此外,该技术降低了对传统化学品的依赖,减少了环境污染。总体而言,本研究为促进CTP技术的可持续发展提供了新的方法。
基金the Natural Science Foundation Committee of China (NSFC,No.81671803)the National Key Research and Development Program (No.2017YFC0107700)+6 种基金the Outstanding Youth Foundation of Jiangsu Province (Nos.GX20171114003, BK20170030)Fok Ying Tung Education Foundation (No.161033)"Double First-Class" University Project (Nos.CPU2018GY06 and CPU2018GY24)the Priority Academic Program Development of Jiangsu Higher Education Institutions for their financial supportthe National Natural Science Foundation of China (Nos.21676113,21402057,21772054,21472059)Distinguished Young Scholar of Hubei Province (No.2018CFA079) for the financial supportsupported by the 111 Project (No.B17019)
文摘Photodynamic therapy(PDT) has shown promise as an effective treatment modality for cancer and other localized diseases due to its noninvasive properties and spatiotemporal selectivity. Near-infrared(NIR)fluorescent dyes based on organic small molecules are characterized with low cytotoxicity, good biocompatibility and excellent phototoxicity, which are widely used in PDT. In this review, we attempt to summarize the development of imaging-induced PDT based on organic small molecules and classify it according to the structures of dyes including cyanines, 4,4-difluoro-4-bora-3 a,4 a-diaza-s-indacene(BODIPY) analogues, phthalocyanine and other agents such as rhodamine analogues.
基金the Natural Science Foundation Committee of China(NSFC, No. 81671803)the National Key Research and Development Program(No. 2017YFC0107700)+6 种基金the Outstanding Youth Foundation of Jiangsu Province (Nos. GX20171114003, BK20170030)Fok Ying Tung Education Foundation(No. 161033)"Double First-Class" University project(Nos. CPU2018GY06 and CPU2018GY24)the Priority Academic Program Development of Jiangsu Higher Education Institutions, for their financial supportthe National Natural Science Foundation of China(Nos. 21676113,21402057, 21772054, 21472059)Distinguished Young Scholar of Hubei Province(No. 2018CFA079)for the financial supportsupported by the 111 Project (No. B17019)
文摘Near-infrared(NIR)fluorescent dyes based on small organic molecules are characterized with low cytotoxicity,good biocompatibility and minimum interference from auto-fluorescence background,which are widely used in tumor diagnosis.Intensive research on molecular properties and photothermal properties of fluorescent dyes have been explored for non-invasive photothermal treatment of cancer.In this review,we focus on the development of imaging-induced photothermal therapy of small molecules and classification according to the structures of organic molecules including cyanines,phthalocyanines,rhodamine analogues and BODIPYs.
