Orthodontic procedures can be inconvenient in nature.To overcome this problem,accelerated orthodontics play a very important role to reduce existing trouble and discomfort.The most common inconvenience caused during o...Orthodontic procedures can be inconvenient in nature.To overcome this problem,accelerated orthodontics play a very important role to reduce existing trouble and discomfort.The most common inconvenience caused during orthodontic treatment procedures is that they are very time consuming which can result in several drawbacks,including an increased risk of tooth decay,gingival recession,and root resorption.Various methods can be employed to expedite orthodontic treatment by accelerating tooth movement,including surgical-assisted procedures,biological interventions,and the utilization of devices.These approaches effectively reduce the overall period of treatment.The purpose of this review is to study the effective techniques for orthodontic tooth movement as well as highlight various orthodontic accelerating methods in the respective approaches.Some nonsurgical studies indicated that drug-induced methods can have a therapeutic effect on tooth movement.One of the approaches involves the local administration of Vitamin 1.25D,which has been found to expedite tooth movement.Vibrational orthodontic devices are a painless and cost-effective option that is considered the least invasive approach for accelerating tooth movement.Meanwhile,surgical approach is also a successful method,wherein great results and strong PDL tissue response were observed,but they cause a lot of pain and discomfort to the patient.Therefore,due to the strengths and limitations of each procedure covered in the study,more research should be done to identify the fastest way to speed up tooth mobility。展开更多
Modified constraint-induced movement therapy(mCIMT)has shown beneficial effects on motor function improvement after brain injury,but the exact mechanism remains unclear.In this study,amplitude of low frequency fluctua...Modified constraint-induced movement therapy(mCIMT)has shown beneficial effects on motor function improvement after brain injury,but the exact mechanism remains unclear.In this study,amplitude of low frequency fluctuation(ALFF)metrics measured by resting-state functional magnetic resonance imaging was obtained to investigate the efficacy and mechanism of mCIMT in a control co rtical impact(CCI)rat model simulating traumatic brain injury.At 3 days after control co rtical impact model establishment,we found that the mean ALFF(mALFF)signals were decreased in the left motor cortex,somatosensory co rtex,insula cortex and the right motor co rtex,and were increased in the right corpus callosum.After 3 weeks of an 8-hour daily mClMT treatment,the mALFF values were significantly increased in the bilateral hemispheres compared with those at 3 days postoperatively.The mALFF signal valu es of left corpus callosum,left somatosensory cortex,right medial prefro ntal cortex,right motor co rtex,left postero dorsal hippocampus,left motor cortex,right corpus callosum,and right somatosensory cortex were increased in the mCIMT group compared with the control cortical impact group.Finally,we identified brain regions with significantly decreased mALFF valu es at 3 days postoperatively.Pearson correlation coefficients with the right forelimb sliding score indicated that the improvement in motor function of the affected upper limb was associated with an increase in mALFF values in these brain regions.Our findings suggest that functional co rtical plasticity changes after brain injury,and that mCIMT is an effective method to improve affected upper limb motor function by promoting bilateral hemispheric co rtical remodeling.mALFF values correlate with behavio ral changes and can potentially be used as biomarkers to assess dynamic cortical plasticity after traumatic brain injury.展开更多
目的观察头电针结合强制性运动对缺血性脑卒中患者上肢功能的影响。方法采用随机数字表法将80例脑卒中患者分为常规康复组、头电针组、强制运动组(constraint-induced movement therapy,CIMT)及综合干预组(头电针+CIMT),常规康复组采用...目的观察头电针结合强制性运动对缺血性脑卒中患者上肢功能的影响。方法采用随机数字表法将80例脑卒中患者分为常规康复组、头电针组、强制运动组(constraint-induced movement therapy,CIMT)及综合干预组(头电针+CIMT),常规康复组采用神经发育疗法(Bobath技术为主,Brunnstrom技术为辅)强化患侧上肢训练;头电针组采用焦氏头针结合电刺激疗法;强制运动组限制健侧上肢,强化患肢训练;综合干预组采用头电针联合强制运动法进行治疗。分别在治疗前及治疗4、12周观察患者偏瘫上肢FuglMeyer运动功能评分(Fugl-Meyer assessment scale,FMA)、腕关节活动度及手功能分级。结果与本组治疗前比较,治疗4周后,各组患者偏瘫上肢FMA评分明显升高,腕关节活动度及手功能分级均明显改善(P<0.05,P<0.01);但除综合干预组偏瘫腕关节活动度在腕关节背伸及桡偏两个活动方向上较常规康复组明显改善(P<0.05)外,其他各组间FMA评分及手功能分级比较,差异均无统计学意义(P>0.05)。治疗12周后,与常规康复组比较,综合干预组FMA评分升高,偏瘫腕关节活动度及手功能分级均明显改善(P<0.05)。结论常规康复、头电针及强制性运动训练对缺血性脑卒中患者偏瘫上肢功能均有较好的康复效果,但头电针联合CIMT训练作用最为明显,且显效最早。展开更多
基金Dr.Vishwanath Karad MIT-World Peace University,Pune,411038 India and Dr.D.Y.Patil Dental College,and Hospital,Pimpri,Pune-411018 India.
文摘Orthodontic procedures can be inconvenient in nature.To overcome this problem,accelerated orthodontics play a very important role to reduce existing trouble and discomfort.The most common inconvenience caused during orthodontic treatment procedures is that they are very time consuming which can result in several drawbacks,including an increased risk of tooth decay,gingival recession,and root resorption.Various methods can be employed to expedite orthodontic treatment by accelerating tooth movement,including surgical-assisted procedures,biological interventions,and the utilization of devices.These approaches effectively reduce the overall period of treatment.The purpose of this review is to study the effective techniques for orthodontic tooth movement as well as highlight various orthodontic accelerating methods in the respective approaches.Some nonsurgical studies indicated that drug-induced methods can have a therapeutic effect on tooth movement.One of the approaches involves the local administration of Vitamin 1.25D,which has been found to expedite tooth movement.Vibrational orthodontic devices are a painless and cost-effective option that is considered the least invasive approach for accelerating tooth movement.Meanwhile,surgical approach is also a successful method,wherein great results and strong PDL tissue response were observed,but they cause a lot of pain and discomfort to the patient.Therefore,due to the strengths and limitations of each procedure covered in the study,more research should be done to identify the fastest way to speed up tooth mobility。
基金supported by the National Key R&D Program of China,Nos.2020YFC2004202(to DSX),2018 YFC2001600(to XYH)the National Natural Science Foundation of China,Nos.81974358(to DSX),81802249(to XYH)and 82172554(to XYH)。
文摘Modified constraint-induced movement therapy(mCIMT)has shown beneficial effects on motor function improvement after brain injury,but the exact mechanism remains unclear.In this study,amplitude of low frequency fluctuation(ALFF)metrics measured by resting-state functional magnetic resonance imaging was obtained to investigate the efficacy and mechanism of mCIMT in a control co rtical impact(CCI)rat model simulating traumatic brain injury.At 3 days after control co rtical impact model establishment,we found that the mean ALFF(mALFF)signals were decreased in the left motor cortex,somatosensory co rtex,insula cortex and the right motor co rtex,and were increased in the right corpus callosum.After 3 weeks of an 8-hour daily mClMT treatment,the mALFF values were significantly increased in the bilateral hemispheres compared with those at 3 days postoperatively.The mALFF signal valu es of left corpus callosum,left somatosensory cortex,right medial prefro ntal cortex,right motor co rtex,left postero dorsal hippocampus,left motor cortex,right corpus callosum,and right somatosensory cortex were increased in the mCIMT group compared with the control cortical impact group.Finally,we identified brain regions with significantly decreased mALFF valu es at 3 days postoperatively.Pearson correlation coefficients with the right forelimb sliding score indicated that the improvement in motor function of the affected upper limb was associated with an increase in mALFF values in these brain regions.Our findings suggest that functional co rtical plasticity changes after brain injury,and that mCIMT is an effective method to improve affected upper limb motor function by promoting bilateral hemispheric co rtical remodeling.mALFF values correlate with behavio ral changes and can potentially be used as biomarkers to assess dynamic cortical plasticity after traumatic brain injury.
文摘目的观察头电针结合强制性运动对缺血性脑卒中患者上肢功能的影响。方法采用随机数字表法将80例脑卒中患者分为常规康复组、头电针组、强制运动组(constraint-induced movement therapy,CIMT)及综合干预组(头电针+CIMT),常规康复组采用神经发育疗法(Bobath技术为主,Brunnstrom技术为辅)强化患侧上肢训练;头电针组采用焦氏头针结合电刺激疗法;强制运动组限制健侧上肢,强化患肢训练;综合干预组采用头电针联合强制运动法进行治疗。分别在治疗前及治疗4、12周观察患者偏瘫上肢FuglMeyer运动功能评分(Fugl-Meyer assessment scale,FMA)、腕关节活动度及手功能分级。结果与本组治疗前比较,治疗4周后,各组患者偏瘫上肢FMA评分明显升高,腕关节活动度及手功能分级均明显改善(P<0.05,P<0.01);但除综合干预组偏瘫腕关节活动度在腕关节背伸及桡偏两个活动方向上较常规康复组明显改善(P<0.05)外,其他各组间FMA评分及手功能分级比较,差异均无统计学意义(P>0.05)。治疗12周后,与常规康复组比较,综合干预组FMA评分升高,偏瘫腕关节活动度及手功能分级均明显改善(P<0.05)。结论常规康复、头电针及强制性运动训练对缺血性脑卒中患者偏瘫上肢功能均有较好的康复效果,但头电针联合CIMT训练作用最为明显,且显效最早。
