Background:The aim of the study was to explore the regularity of acupoints combination in the treatment of functional dyspepsia(FD)by means of data mining technology.Methods:We conducted a systematic search of nine da...Background:The aim of the study was to explore the regularity of acupoints combination in the treatment of functional dyspepsia(FD)by means of data mining technology.Methods:We conducted a systematic search of nine databases from their inception to December 2022 to identify eligible randomized controlled trials(RCTs).The acupoints prescriptions in the treatment of FD were extracted and analyzed based on association rule mining and network analysis.Furthermore,the acupoints prescribed for irritability symptom of FD were quantified by forward inference,reverse inference and Bayes factor(BF)correction.Results:A total of 45 RCTs on 30 acupoints were included,involving 172 times the total application frequency.Analysis of acupoints prescriptions covered 29 meridian acupoints and one extra-ordinary point,disturbing in 10 meridians.The top three acupoints in application frequency were Zusanli(ST36,19.77%),Neiguan(PC6,16.86%),Zhongwan(CV12,12.21%).The most involved meridian was the foot yangming stomach meridian(34 times).The most frequently used acupoints combinations were PC6 and ST36.The core prescriptions were ST36,PC6,Tianshu(ST25),CV12.The specificities of acupoints selection for FD with dysphoria as follows:using the forward inference,PC6,Taichong(LR3),Qimen(LR14),CV12,Danzhong(CV17),ST25,ST36 were selected.Using the reverse inference and BF correction,PC6,CV12,CV17,Sanyinjiao(SP6),ST25,ST36 were selected.展开更多
The present investigation deals with the isolation of endophytic fungi from leaf,stem,root and pitcher cup tissue segments of the endemic carnivorous plant Nepenthes khaisana collected from its natural habitat for a p...The present investigation deals with the isolation of endophytic fungi from leaf,stem,root and pitcher cup tissue segments of the endemic carnivorous plant Nepenthes khaisana collected from its natural habitat for a period of one year at monthly intervals.Out of 576 tissue segments inoculated,a total of 39 fungal endophytes along with mycelia sterilia were isolated from the host plant.To assess the diversity of fungal endophytes,the colonization frequency(%CF)was first recorded using past software and MS excel.The fungal isolates were mainly composed of the phylum Ascomycota,followed by Zygomycota and Oomycota.The highest percentage colonization frequency on an average of three replicates were recorded in pitcher cup tissues followed by root,stem and least was recorded in leaf of the host plant.Among the isolates,Globisporangium irregulare(83.33%)showed high%CF in leaf,Juxtiphoma eupyrena(83.33%)reported to have maximum%CF in the stem,Talaromyces ruber(66.66%)was recorded high%CF in root and mycelia sterilia(white)were showed the highest%CF in the segments of leaf.The diversity index analyses of Shannon-Weiner,Simpson’s index,species richness and species evenness of diversity showed that leaf of N.Khasiana has the highest diversity than the other parts of the plant.So,with the help of the present finding,we conclude that the distribution of fungal endophytes and their%colonization frequencies vary within different tissues of the host plant and thus,this confirms tissue specificity nature of endophytic fungi.展开更多
Objective To screen the high specific and sensitivemonitoring indications in the diagnosis of intestinal barrier dysfunction.Methods A total of 70 critical patients with intestinal barrier dysfunction and acute
基金Supported by Zhejiang Provincial Natural Science Fund of China:LY20H270006,LY19H270003Zhejiang Medical and Health Science and Technology Program:2021RC098National Natural Science Fund of China:81873360。
文摘Background:The aim of the study was to explore the regularity of acupoints combination in the treatment of functional dyspepsia(FD)by means of data mining technology.Methods:We conducted a systematic search of nine databases from their inception to December 2022 to identify eligible randomized controlled trials(RCTs).The acupoints prescriptions in the treatment of FD were extracted and analyzed based on association rule mining and network analysis.Furthermore,the acupoints prescribed for irritability symptom of FD were quantified by forward inference,reverse inference and Bayes factor(BF)correction.Results:A total of 45 RCTs on 30 acupoints were included,involving 172 times the total application frequency.Analysis of acupoints prescriptions covered 29 meridian acupoints and one extra-ordinary point,disturbing in 10 meridians.The top three acupoints in application frequency were Zusanli(ST36,19.77%),Neiguan(PC6,16.86%),Zhongwan(CV12,12.21%).The most involved meridian was the foot yangming stomach meridian(34 times).The most frequently used acupoints combinations were PC6 and ST36.The core prescriptions were ST36,PC6,Tianshu(ST25),CV12.The specificities of acupoints selection for FD with dysphoria as follows:using the forward inference,PC6,Taichong(LR3),Qimen(LR14),CV12,Danzhong(CV17),ST25,ST36 were selected.Using the reverse inference and BF correction,PC6,CV12,CV17,Sanyinjiao(SP6),ST25,ST36 were selected.
文摘The present investigation deals with the isolation of endophytic fungi from leaf,stem,root and pitcher cup tissue segments of the endemic carnivorous plant Nepenthes khaisana collected from its natural habitat for a period of one year at monthly intervals.Out of 576 tissue segments inoculated,a total of 39 fungal endophytes along with mycelia sterilia were isolated from the host plant.To assess the diversity of fungal endophytes,the colonization frequency(%CF)was first recorded using past software and MS excel.The fungal isolates were mainly composed of the phylum Ascomycota,followed by Zygomycota and Oomycota.The highest percentage colonization frequency on an average of three replicates were recorded in pitcher cup tissues followed by root,stem and least was recorded in leaf of the host plant.Among the isolates,Globisporangium irregulare(83.33%)showed high%CF in leaf,Juxtiphoma eupyrena(83.33%)reported to have maximum%CF in the stem,Talaromyces ruber(66.66%)was recorded high%CF in root and mycelia sterilia(white)were showed the highest%CF in the segments of leaf.The diversity index analyses of Shannon-Weiner,Simpson’s index,species richness and species evenness of diversity showed that leaf of N.Khasiana has the highest diversity than the other parts of the plant.So,with the help of the present finding,we conclude that the distribution of fungal endophytes and their%colonization frequencies vary within different tissues of the host plant and thus,this confirms tissue specificity nature of endophytic fungi.
文摘Objective To screen the high specific and sensitivemonitoring indications in the diagnosis of intestinal barrier dysfunction.Methods A total of 70 critical patients with intestinal barrier dysfunction and acute
