以木质素磺酸钠(LS)、丙烯酰胺(AM)、马来酸酐(MAH)为原料,膨润土(Ben)为无机添加剂,过硫酸钾(KPS)为引发剂,N,N′-亚甲基双丙烯酰胺(NMBA)为交联剂,通过溶液自由基接枝共聚法制备了膨润土/木质素磺酸钠接枝丙烯酰胺-马来酸酐(Ben/LS-g-...以木质素磺酸钠(LS)、丙烯酰胺(AM)、马来酸酐(MAH)为原料,膨润土(Ben)为无机添加剂,过硫酸钾(KPS)为引发剂,N,N′-亚甲基双丙烯酰胺(NMBA)为交联剂,通过溶液自由基接枝共聚法制备了膨润土/木质素磺酸钠接枝丙烯酰胺-马来酸酐(Ben/LS-g-AM-co-MAH)选择性吸附树脂。采用元素分析(EA)、比表面积和孔径分析(BET)、FTIR、核磁共振碳谱(13 C NMR)、XRD、SEM-EDS及XPS对所得吸附树脂的组成与结构进行了表征。结果表明:Ben/LS-g-AM-co-MAH的结构中含有大量的酰胺基和羧基基团,其在二元Pb2+/Cu2+溶液中对Pb2+具有较高的吸附量以及良好的吸附选择性。展开更多
This article deals with the exploration of the design of network crosslinked structure by covalent bonding for use as wound dressing materials keeping in view inherent therapeutic role of neem gum in wound healing.The...This article deals with the exploration of the design of network crosslinked structure by covalent bonding for use as wound dressing materials keeping in view inherent therapeutic role of neem gum in wound healing.These copolymeric hydrogels were prepared by graft-copolymerization reaction of carbopol and poly(N-vinylpyrrolidone)(poly(NVP).Antibiotic drug levofloxacin was encapsulated in dressings for better wound healing.The scanning electron microscopy(SEM),atomic force microscopy(AFM),Fourier transform infrared(FTIR)spectroscopy,^(13)C nuclear magnetic resonance(NMR)spectroscopy,X-ray diffraction(XRD),thermogravimetric analysis(TGA),differential thermal gravimetry(DTG),and differential scanning calorimetry(DSC)techniques were applied for characterization.NMR and FTIR demonstrated incorporation of carbapol and poly(NVP)in dressings.XRD indicated amorphous state in copolymeric dressings.Interactions of copolymers with drug,blood and bio membrane were studied to evaluate biomedical properties which revealed controlled release of drug from hydrogel dressings which were possessing blood-compatible(haemolytic value=2.4±0.82)and mucoadhesive(detachment force=124±41 mN)properties.Dressings were permeable to O2 and H2O vapour and absorbed 6.68±±0.62 g/g wound fluid which is ideal dressing characteristic.Diffusion mechanism type of drug levofloxacin was Fickian with kinetic model First order.These properties suggested use of hydrogel material for wound dressing and drug delivery applications for better wound care management.This article deals with the exploration of the design of network crosslinked structure by covalent bonding for use as wound dressing materials keeping in view inherent therapeutic role of neem gum in wound healing.These copolymeric hydrogels were prepared by graft-copolymerization reaction of carbopol and poly(N-vinylpyrrolidone)(poly(NVP).Antibiotic drug levofloxacin was encapsulated in dressings for better wound healing.The scanning electron microscopy(SEM),atomic force microscopy(AFM),Fourier 展开更多
文摘以木质素磺酸钠(LS)、丙烯酰胺(AM)、马来酸酐(MAH)为原料,膨润土(Ben)为无机添加剂,过硫酸钾(KPS)为引发剂,N,N′-亚甲基双丙烯酰胺(NMBA)为交联剂,通过溶液自由基接枝共聚法制备了膨润土/木质素磺酸钠接枝丙烯酰胺-马来酸酐(Ben/LS-g-AM-co-MAH)选择性吸附树脂。采用元素分析(EA)、比表面积和孔径分析(BET)、FTIR、核磁共振碳谱(13 C NMR)、XRD、SEM-EDS及XPS对所得吸附树脂的组成与结构进行了表征。结果表明:Ben/LS-g-AM-co-MAH的结构中含有大量的酰胺基和羧基基团,其在二元Pb2+/Cu2+溶液中对Pb2+具有较高的吸附量以及良好的吸附选择性。
文摘This article deals with the exploration of the design of network crosslinked structure by covalent bonding for use as wound dressing materials keeping in view inherent therapeutic role of neem gum in wound healing.These copolymeric hydrogels were prepared by graft-copolymerization reaction of carbopol and poly(N-vinylpyrrolidone)(poly(NVP).Antibiotic drug levofloxacin was encapsulated in dressings for better wound healing.The scanning electron microscopy(SEM),atomic force microscopy(AFM),Fourier transform infrared(FTIR)spectroscopy,^(13)C nuclear magnetic resonance(NMR)spectroscopy,X-ray diffraction(XRD),thermogravimetric analysis(TGA),differential thermal gravimetry(DTG),and differential scanning calorimetry(DSC)techniques were applied for characterization.NMR and FTIR demonstrated incorporation of carbapol and poly(NVP)in dressings.XRD indicated amorphous state in copolymeric dressings.Interactions of copolymers with drug,blood and bio membrane were studied to evaluate biomedical properties which revealed controlled release of drug from hydrogel dressings which were possessing blood-compatible(haemolytic value=2.4±0.82)and mucoadhesive(detachment force=124±41 mN)properties.Dressings were permeable to O2 and H2O vapour and absorbed 6.68±±0.62 g/g wound fluid which is ideal dressing characteristic.Diffusion mechanism type of drug levofloxacin was Fickian with kinetic model First order.These properties suggested use of hydrogel material for wound dressing and drug delivery applications for better wound care management.This article deals with the exploration of the design of network crosslinked structure by covalent bonding for use as wound dressing materials keeping in view inherent therapeutic role of neem gum in wound healing.These copolymeric hydrogels were prepared by graft-copolymerization reaction of carbopol and poly(N-vinylpyrrolidone)(poly(NVP).Antibiotic drug levofloxacin was encapsulated in dressings for better wound healing.The scanning electron microscopy(SEM),atomic force microscopy(AFM),Fourier
