Objective The aim of our study was to assess the complications of hepatic fibrosis associated with bile duct ligation and the potential curative role of sepia ink extract in hepatic damage induced by bile duct ligatio...Objective The aim of our study was to assess the complications of hepatic fibrosis associated with bile duct ligation and the potential curative role of sepia ink extract in hepatic damage induced by bile duct ligation. Methods Rattus norvegicus rats were divided into 3 groups: Sham-operated group, model rats that underwent common bile duct ligation (BDL), and BDL rats treated orally with sepia ink extract (200 mg/kg body weight) for 7, 14, and 28 d after BDL. Results There was a significant reduction in hepatic enzymes, ALP, GGT, bilirubin levels, and oxidative stress in the BDL group after treatment with sepia ink extract. Collagen deposition reduced after sepia ink extract treatment as compared to BDL groups, suggesting that the liver was repaired. Histopathological examination of liver treated with sepia ink extract showed moderate degeneration in the hepatic architecture and mild degeneration in hepatocytes as compared to BDL groups. Conclusion Sepia ink extract provides a curative effect and an antioxidant capacity on BDL rats and could ameliorate the complications of liver cholestasis.展开更多
To investigate the correlation between anxiety and related factors among international students in Wenzhou during the COVID-19 epidemic,international students from Wenzhou were selected as subjects for our research.We...To investigate the correlation between anxiety and related factors among international students in Wenzhou during the COVID-19 epidemic,international students from Wenzhou were selected as subjects for our research.We administered a self-developed questionnaire on anxiety among our subjects in question during the specific time of the COVID-19 epidemic,in which a self-assessment scale was included.Overall,an anxiety questionnaire for international students studying in Wenzhou during the outbreak of COVID–19,a self-rating anxiety scale,and statistical methods were utilized to conduct our research.During the COVID-19 epidemic,international students in Wenzhou experienced varying degrees of anxiety,which were related to concerns about contracting the virus,exam-related stress,and differences in living standards.Therefore,intervention is crucial.展开更多
文摘Objective The aim of our study was to assess the complications of hepatic fibrosis associated with bile duct ligation and the potential curative role of sepia ink extract in hepatic damage induced by bile duct ligation. Methods Rattus norvegicus rats were divided into 3 groups: Sham-operated group, model rats that underwent common bile duct ligation (BDL), and BDL rats treated orally with sepia ink extract (200 mg/kg body weight) for 7, 14, and 28 d after BDL. Results There was a significant reduction in hepatic enzymes, ALP, GGT, bilirubin levels, and oxidative stress in the BDL group after treatment with sepia ink extract. Collagen deposition reduced after sepia ink extract treatment as compared to BDL groups, suggesting that the liver was repaired. Histopathological examination of liver treated with sepia ink extract showed moderate degeneration in the hepatic architecture and mild degeneration in hepatocytes as compared to BDL groups. Conclusion Sepia ink extract provides a curative effect and an antioxidant capacity on BDL rats and could ameliorate the complications of liver cholestasis.
基金2022 annual curriculum ideological and political teaching reform research project of Wenzhou Medical University and 2022“big ideological and political”teaching reform project of The First Affiliated Hospital of Wenzhou Medical University.(jglx202210)。
文摘To investigate the correlation between anxiety and related factors among international students in Wenzhou during the COVID-19 epidemic,international students from Wenzhou were selected as subjects for our research.We administered a self-developed questionnaire on anxiety among our subjects in question during the specific time of the COVID-19 epidemic,in which a self-assessment scale was included.Overall,an anxiety questionnaire for international students studying in Wenzhou during the outbreak of COVID–19,a self-rating anxiety scale,and statistical methods were utilized to conduct our research.During the COVID-19 epidemic,international students in Wenzhou experienced varying degrees of anxiety,which were related to concerns about contracting the virus,exam-related stress,and differences in living standards.Therefore,intervention is crucial.
