The study on wetland ecosystem health(WEH) belongs to a new field.At present,there is not an operational definition into practice yet,and the information from national and international studies on WEH is not enough to...The study on wetland ecosystem health(WEH) belongs to a new field.At present,there is not an operational definition into practice yet,and the information from national and international studies on WEH is not enough to form a system.Especially in China the studies just begin and need to investigate and get more information and knowledge.Based on the present situations of wetland ecosystem,the paper gives the concept of wetland ecosystem health and its related history.The research status on WEH is also presented,including health diagnostic indicators,wetland restoration and research scale.Finally,the paper analyzes the developing trends in WEH research.展开更多
目的:探讨诊断骨科患者围术期并发静脉血栓栓塞症(VTE)相关指标变化及其准确性。方法:采用回顾性病例对照研究分析2015年1月至2019年9月重庆市合川区人民医院收治的109例初次行人工全髋关节置换术(THA)、人工全膝关节置换术(TKA)或股骨...目的:探讨诊断骨科患者围术期并发静脉血栓栓塞症(VTE)相关指标变化及其准确性。方法:采用回顾性病例对照研究分析2015年1月至2019年9月重庆市合川区人民医院收治的109例初次行人工全髋关节置换术(THA)、人工全膝关节置换术(TKA)或股骨近端防旋髓内钉(PFNA)内固定围术期患者临床资料,其中男55例,女54例;年龄18~76岁[(46.3 ± 11.2)岁]。股骨头坏死和股骨颈骨折行单侧THA治疗54例,骨性关节炎行单侧TKA治疗36例,股骨近端骨折行PFNA治疗19例。47例确诊VTE(VTE组),62例未发生VTE(非VTE组)。所有患者入院时、术后1,3,5,7 d采集静脉血,比较两组血浆D-二聚体、血清白细胞介素(IL)-18和血管内皮生长因子(VEGF)水平。绘制受试者工作特征(ROC)曲线,分析上述指标对VTE诊断的准确性。结果:两组入院时各项指标均低于术后各时相点,术后各项指标差异均有统计学意义( P < 0.05或0.01)。与非VTE组比较,VTE组术后各时相点D-二聚体、IL-18和VEGF水平均明显升高( P < 0.05或0.01)。D-二聚体的ROC曲线下面积(AUC)为0.839,95% CI 0.729~0.887,此时最佳截断值为5.5 μg/ml,灵敏度、特异度分别为87.0%、79.0%,约登指数为0.670;IL-18的AUC为0.817,95% CI 0.719~0.857,此时最佳截断值为293.5 pg/ml,灵敏度、特异度分别为67.0%、87.1%,约登指数为0.457;VEGF的AUC为0.837,95% CI 0.784~0.918,此时最佳截断值为510.8 pg/ml,灵敏度、特异度分别为81.0%、79.0%,约登指数为0.583。联合D-二聚体、IL-18和VEGF的AUC为0.870,95% CI 0.747~0.992,灵敏度、特异度分别为87.2%、83.4%,约登指数为0.606。 结论:对于骨科围术期患者VTE的诊断,血清VEGF有一定的准确性,血清IL-18则准确性不高,但可通过联合检测血浆D-二聚体、IL-18和VEGF,提高对VTE诊断的准确性。展开更多
文摘The study on wetland ecosystem health(WEH) belongs to a new field.At present,there is not an operational definition into practice yet,and the information from national and international studies on WEH is not enough to form a system.Especially in China the studies just begin and need to investigate and get more information and knowledge.Based on the present situations of wetland ecosystem,the paper gives the concept of wetland ecosystem health and its related history.The research status on WEH is also presented,including health diagnostic indicators,wetland restoration and research scale.Finally,the paper analyzes the developing trends in WEH research.
文摘目的:探讨诊断骨科患者围术期并发静脉血栓栓塞症(VTE)相关指标变化及其准确性。方法:采用回顾性病例对照研究分析2015年1月至2019年9月重庆市合川区人民医院收治的109例初次行人工全髋关节置换术(THA)、人工全膝关节置换术(TKA)或股骨近端防旋髓内钉(PFNA)内固定围术期患者临床资料,其中男55例,女54例;年龄18~76岁[(46.3 ± 11.2)岁]。股骨头坏死和股骨颈骨折行单侧THA治疗54例,骨性关节炎行单侧TKA治疗36例,股骨近端骨折行PFNA治疗19例。47例确诊VTE(VTE组),62例未发生VTE(非VTE组)。所有患者入院时、术后1,3,5,7 d采集静脉血,比较两组血浆D-二聚体、血清白细胞介素(IL)-18和血管内皮生长因子(VEGF)水平。绘制受试者工作特征(ROC)曲线,分析上述指标对VTE诊断的准确性。结果:两组入院时各项指标均低于术后各时相点,术后各项指标差异均有统计学意义( P < 0.05或0.01)。与非VTE组比较,VTE组术后各时相点D-二聚体、IL-18和VEGF水平均明显升高( P < 0.05或0.01)。D-二聚体的ROC曲线下面积(AUC)为0.839,95% CI 0.729~0.887,此时最佳截断值为5.5 μg/ml,灵敏度、特异度分别为87.0%、79.0%,约登指数为0.670;IL-18的AUC为0.817,95% CI 0.719~0.857,此时最佳截断值为293.5 pg/ml,灵敏度、特异度分别为67.0%、87.1%,约登指数为0.457;VEGF的AUC为0.837,95% CI 0.784~0.918,此时最佳截断值为510.8 pg/ml,灵敏度、特异度分别为81.0%、79.0%,约登指数为0.583。联合D-二聚体、IL-18和VEGF的AUC为0.870,95% CI 0.747~0.992,灵敏度、特异度分别为87.2%、83.4%,约登指数为0.606。 结论:对于骨科围术期患者VTE的诊断,血清VEGF有一定的准确性,血清IL-18则准确性不高,但可通过联合检测血浆D-二聚体、IL-18和VEGF,提高对VTE诊断的准确性。
