目的研究中枢神经系统(central nervous system,CNS)畸形合并羊水过多胎儿产尿率(urine production rate,UPR)的改变情况。方法选取58例正常单胎妊娠的胎儿作为正常对照组,选择同期连续性检测的20例CNS畸形合并羊水过多的胎儿作为病例组...目的研究中枢神经系统(central nervous system,CNS)畸形合并羊水过多胎儿产尿率(urine production rate,UPR)的改变情况。方法选取58例正常单胎妊娠的胎儿作为正常对照组,选择同期连续性检测的20例CNS畸形合并羊水过多的胎儿作为病例组,并将其中的5例无脑畸形列为CNS畸形亚组。应用三维超声虚拟器官计算机辅助分析(virtual organ computer-aided analysis,VO-CAL)技术分别测量各组胎儿的膀胱体积并计算胎儿UPR,经过Z-score转换消除孕周影响,测得的病例组Z值分别与对照组进行比较。结果 CNS畸形组和无脑畸形组胎儿UPR与对照组均无明显差异(均P>0.05)。结论无论是无脑畸形还是其他类型,CNS畸形胎儿UPR正常,即CNS畸形合并羊水过多并非由于胎尿生成增多所致。展开更多
AIM: To investigate the characteristics of postoperative central visual field defect(cVFD) in patients with macular hole(MH).METHODS: Eighteen eyes from 18 MH patients were involved in this retrospective study which r...AIM: To investigate the characteristics of postoperative central visual field defect(cVFD) in patients with macular hole(MH).METHODS: Eighteen eyes from 18 MH patients were involved in this retrospective study which reviewed square root of loss variance(sLV) and mean defect(MD) of the visual field test in all subjects. The relationship between cVFD and MH stage, as well as the postoperative ellipsoid zone disruption were evaluated using Spearman's correlation test. RESULTS: Our analysis determined Spearman coefficient is 0.705 for the correlation between sLV and MH stage(P<0.01), 0.877 for the correlation between sLV and postoperative ellipsoid zone disruption(P<0.01) and 0.721 for the correlation between MD and postoperative ellipsoid zone disruption(P<0.01). A significant relationship was also detected between postoperative ellipsoid zone disruption and MH stage(r=0.470, P<0.05). Univariate regression analysis indicated that sLV and MD were associated with postoperative ellipsoid zone disruption(P<0.01, P<0.01, respectively). CONCLUSION: Postoperative cVFD is highly correlated with MH stage and postoperative ellipsoid zone disruption in patients with MH.展开更多
<strong>Background:</strong><span "=""> Macular hole is a known cause of central visual defect with varying etiologies in different parts of the world. It was considered an untreatable...<strong>Background:</strong><span "=""> Macular hole is a known cause of central visual defect with varying etiologies in different parts of the world. It was considered an untreatable condition until 1991 when varying treatment techniques began to emerge with resultant restoration of central vision. This study was carried out to evaluate the prevalence and pattern of Macular hole in a tertiary eye centre in Nigeria. <b>Method:</b> This is a prospective hospital</span>-<span "="">based study over a 5 year period spanning from November 2013 to October 2018. All patients with macular hole seen within this period were included in the study. Relevant data were recorded with a structured questionnaire and analysed with SPSS version 20. <b>Results:</b> There were 46 eyes of 42 patients which constituted about 0.5% of all new patients seen over the study period. Male to female ratio was 1:1.3 with age ranged between 15 and 91years (mean</span><span "=""> </span>=<span "=""> </span>61.8<span "=""> </span>±<span "=""> </span>16.5<span "=""> </span>years). The majority of <span "="">the patients (95.7%) had Idiopathic macular hole. Half of the patients (54.8%) had visual acuity less than 3/60 in the affected eye at the time of presentation. The majority (95.7%) of the patients did not accept the recommended surgical treatment option because of financial incapacitation. <b>Conclusion:</b> Macular hole is a disease of marked visual consequence. Available treatment option is still not within the reach of the majority because of the high cost.展开更多
文摘目的研究中枢神经系统(central nervous system,CNS)畸形合并羊水过多胎儿产尿率(urine production rate,UPR)的改变情况。方法选取58例正常单胎妊娠的胎儿作为正常对照组,选择同期连续性检测的20例CNS畸形合并羊水过多的胎儿作为病例组,并将其中的5例无脑畸形列为CNS畸形亚组。应用三维超声虚拟器官计算机辅助分析(virtual organ computer-aided analysis,VO-CAL)技术分别测量各组胎儿的膀胱体积并计算胎儿UPR,经过Z-score转换消除孕周影响,测得的病例组Z值分别与对照组进行比较。结果 CNS畸形组和无脑畸形组胎儿UPR与对照组均无明显差异(均P>0.05)。结论无论是无脑畸形还是其他类型,CNS畸形胎儿UPR正常,即CNS畸形合并羊水过多并非由于胎尿生成增多所致。
基金Supported by National Natural Science Foundation of China(No.81670865 No.81500743)Natural Science Foundation of Tianjin(No.16JCQNJC13000)
文摘AIM: To investigate the characteristics of postoperative central visual field defect(cVFD) in patients with macular hole(MH).METHODS: Eighteen eyes from 18 MH patients were involved in this retrospective study which reviewed square root of loss variance(sLV) and mean defect(MD) of the visual field test in all subjects. The relationship between cVFD and MH stage, as well as the postoperative ellipsoid zone disruption were evaluated using Spearman's correlation test. RESULTS: Our analysis determined Spearman coefficient is 0.705 for the correlation between sLV and MH stage(P<0.01), 0.877 for the correlation between sLV and postoperative ellipsoid zone disruption(P<0.01) and 0.721 for the correlation between MD and postoperative ellipsoid zone disruption(P<0.01). A significant relationship was also detected between postoperative ellipsoid zone disruption and MH stage(r=0.470, P<0.05). Univariate regression analysis indicated that sLV and MD were associated with postoperative ellipsoid zone disruption(P<0.01, P<0.01, respectively). CONCLUSION: Postoperative cVFD is highly correlated with MH stage and postoperative ellipsoid zone disruption in patients with MH.
文摘<strong>Background:</strong><span "=""> Macular hole is a known cause of central visual defect with varying etiologies in different parts of the world. It was considered an untreatable condition until 1991 when varying treatment techniques began to emerge with resultant restoration of central vision. This study was carried out to evaluate the prevalence and pattern of Macular hole in a tertiary eye centre in Nigeria. <b>Method:</b> This is a prospective hospital</span>-<span "="">based study over a 5 year period spanning from November 2013 to October 2018. All patients with macular hole seen within this period were included in the study. Relevant data were recorded with a structured questionnaire and analysed with SPSS version 20. <b>Results:</b> There were 46 eyes of 42 patients which constituted about 0.5% of all new patients seen over the study period. Male to female ratio was 1:1.3 with age ranged between 15 and 91years (mean</span><span "=""> </span>=<span "=""> </span>61.8<span "=""> </span>±<span "=""> </span>16.5<span "=""> </span>years). The majority of <span "="">the patients (95.7%) had Idiopathic macular hole. Half of the patients (54.8%) had visual acuity less than 3/60 in the affected eye at the time of presentation. The majority (95.7%) of the patients did not accept the recommended surgical treatment option because of financial incapacitation. <b>Conclusion:</b> Macular hole is a disease of marked visual consequence. Available treatment option is still not within the reach of the majority because of the high cost.
