Urotensin-Ⅱ is the most potent vasoconstrictor peptide ever identified.A great number of studies about hemodynamics of urotensin-Ⅱ were reported.Recently,many researches have demonstrated that urotensin-Ⅱ also has ...Urotensin-Ⅱ is the most potent vasoconstrictor peptide ever identified.A great number of studies about hemodynamics of urotensin-Ⅱ were reported.Recently,many researches have demonstrated that urotensin-Ⅱ also has nonhemodynamic effects,such as mitogenic action,stimulating cell proliferation,promoting extracellular matrix production and so on.Nonhemodynamic effects of urotensin-Ⅱ may play a role in the pathogenesis of some diseases.展开更多
基金This work was supported by the Major State Basic Research Development Program of People's Republic of China ( No. G2000056905) and the National Natural Science Fundation of China (No. 30070306).
文摘Urotensin-Ⅱ is the most potent vasoconstrictor peptide ever identified.A great number of studies about hemodynamics of urotensin-Ⅱ were reported.Recently,many researches have demonstrated that urotensin-Ⅱ also has nonhemodynamic effects,such as mitogenic action,stimulating cell proliferation,promoting extracellular matrix production and so on.Nonhemodynamic effects of urotensin-Ⅱ may play a role in the pathogenesis of some diseases.
