Background Self-monitoring of blood glucose （SMBG） by individuals with type 2 diabetes （T2D） is crucial for long-term health,yet numerous cultural,economic and health factors can reduce SMBG.Most studies on SMBG a...Background Self-monitoring of blood glucose （SMBG） by individuals with type 2 diabetes （T2D） is crucial for long-term health,yet numerous cultural,economic and health factors can reduce SMBG.Most studies on SMBG adherence have come out of the US and Europe,and their relevance to Asia is unclear.The aims of the present study were to assess the current state of SMBG in China and analyze demographic and diabetes-related characteristics that may influence it.Methods In this multi-center,cross-sectional study,5 953 individuals with T2D from 50 medical centers in 29 provinces across China filled out a standardized questionnaire that requested information on demographic characteristics,education level,occupation,income,lifestyle risk factors,duration of diabetes,chronic complications,and frequency of SMBG.Respondents were also asked whether their glycosylated hemoglobin （HbA1c） had been checked in the past 6 months.The most recent values for fasting plasma glucose,2-hour postprandial blood glucose and HbA1c were recovered from medical records.Results Only 1 130 respondents （18.98％） performed SMBG with the recommended frequency,while 4 823 （81.02％） did not.In fact,nearly 2 105 （35.36％） reported never performing SMBG.In the subset of 3 661 individuals on insulin therapy,only 266 （7.27％） performed SMBG at least once a day,while 1 210 （33.05％） never performed it.In contrast,895 of 2 292 individuals （39.05％） on diet/exercise therapy or oral hypoglycemic therapy never performed it.Multivariate Logistic regression identified several factors associated with SMBG adherence：female gender,higher education level,higher income,longer T2D duration and education about SMBG.Conclusions SMBG adherence in our Chinese population with T2D was less frequent than that in developed countries.Several factors influence SMBG adherence：gender,education level,income,T2D duration,therapy regimen and exposure to education about SMBG.展开更多
目的总结应用艾塞那肽成功替代胰岛素治疗的2型糖尿病患者的临床特点,并比较胰岛素和艾塞那肽的降糖效果以及对血糖稳定性的影响。方法回顾分析了成功应用艾塞那肽替代胰岛素治疗的21例2型糖尿病患者的临床资料和自我血糖监测记录,应用...目的总结应用艾塞那肽成功替代胰岛素治疗的2型糖尿病患者的临床特点,并比较胰岛素和艾塞那肽的降糖效果以及对血糖稳定性的影响。方法回顾分析了成功应用艾塞那肽替代胰岛素治疗的21例2型糖尿病患者的临床资料和自我血糖监测记录,应用配对t检验对患者先后应用胰岛素和艾塞那肽治疗期间的血糖值进行比较分析。结果患者多为中青年,糖尿病病程短,体型肥胖,平均糖化血红蛋白为(9.9±3.0)%,空腹C肽为(0.43±0.13)pmol/ml,餐后2 h C肽为(1.08±0.66)pmol/ml。应用艾塞那肽期间,患者血糖水平和达标率明显优于胰岛素治疗期间的血糖(P<0.01),同时全天血糖标准差、最大血糖波动幅度、四分位血糖波动范围、餐后血糖波动幅度、空腹血糖变异系数和日间血糖平均绝对差均明显低于胰岛素治疗期间的血糖波动情况(P<0.05)。回归分析结果显示血糖波动性指标主要与餐后血糖呈正相关,与空腹血糖无关。结论胰岛功能轻度受损的肥胖2型糖尿病患者应用艾塞那肽不仅可以良好地控制血糖,而且能够减少血糖的波动性。展开更多
文摘Background Self-monitoring of blood glucose （SMBG） by individuals with type 2 diabetes （T2D） is crucial for long-term health,yet numerous cultural,economic and health factors can reduce SMBG.Most studies on SMBG adherence have come out of the US and Europe,and their relevance to Asia is unclear.The aims of the present study were to assess the current state of SMBG in China and analyze demographic and diabetes-related characteristics that may influence it.Methods In this multi-center,cross-sectional study,5 953 individuals with T2D from 50 medical centers in 29 provinces across China filled out a standardized questionnaire that requested information on demographic characteristics,education level,occupation,income,lifestyle risk factors,duration of diabetes,chronic complications,and frequency of SMBG.Respondents were also asked whether their glycosylated hemoglobin （HbA1c） had been checked in the past 6 months.The most recent values for fasting plasma glucose,2-hour postprandial blood glucose and HbA1c were recovered from medical records.Results Only 1 130 respondents （18.98％） performed SMBG with the recommended frequency,while 4 823 （81.02％） did not.In fact,nearly 2 105 （35.36％） reported never performing SMBG.In the subset of 3 661 individuals on insulin therapy,only 266 （7.27％） performed SMBG at least once a day,while 1 210 （33.05％） never performed it.In contrast,895 of 2 292 individuals （39.05％） on diet/exercise therapy or oral hypoglycemic therapy never performed it.Multivariate Logistic regression identified several factors associated with SMBG adherence：female gender,higher education level,higher income,longer T2D duration and education about SMBG.Conclusions SMBG adherence in our Chinese population with T2D was less frequent than that in developed countries.Several factors influence SMBG adherence：gender,education level,income,T2D duration,therapy regimen and exposure to education about SMBG.
文摘目的总结应用艾塞那肽成功替代胰岛素治疗的2型糖尿病患者的临床特点,并比较胰岛素和艾塞那肽的降糖效果以及对血糖稳定性的影响。方法回顾分析了成功应用艾塞那肽替代胰岛素治疗的21例2型糖尿病患者的临床资料和自我血糖监测记录,应用配对t检验对患者先后应用胰岛素和艾塞那肽治疗期间的血糖值进行比较分析。结果患者多为中青年,糖尿病病程短,体型肥胖,平均糖化血红蛋白为(9.9±3.0)%,空腹C肽为(0.43±0.13)pmol/ml,餐后2 h C肽为(1.08±0.66)pmol/ml。应用艾塞那肽期间,患者血糖水平和达标率明显优于胰岛素治疗期间的血糖(P<0.01),同时全天血糖标准差、最大血糖波动幅度、四分位血糖波动范围、餐后血糖波动幅度、空腹血糖变异系数和日间血糖平均绝对差均明显低于胰岛素治疗期间的血糖波动情况(P<0.05)。回归分析结果显示血糖波动性指标主要与餐后血糖呈正相关,与空腹血糖无关。结论胰岛功能轻度受损的肥胖2型糖尿病患者应用艾塞那肽不仅可以良好地控制血糖,而且能够减少血糖的波动性。
