The functional genes underlying phenotypic variation and their interactions represent“genetic mysteries”.Understanding and utilizing these genetic mysteries are key solutions for mitigating the current threats to ag...The functional genes underlying phenotypic variation and their interactions represent“genetic mysteries”.Understanding and utilizing these genetic mysteries are key solutions for mitigating the current threats to agriculture posed by population growth and individual food preferences.Due to advances in highthroughput multi-omics technologies,we are stepping into an Interactome Big Data era that is certain to revolutionize genetic research.In this article,we provide a brief overview of current strategies to explore genetic mysteries.We then introduce the methods for constructing and analyzing the Interactome Big Data and summarize currently available interactome resources.Next,we discuss how Interactome Big Data can be used as a versatile tool to dissect genetic mysteries.We propose an integrated strategy that could revolutionize genetic research by combining Interactome Big Data with machine learning,which involves mining information hidden in Big Data to identify the genetic models or networks that control various traits,and also provide a detailed procedure for systematic dissection of genetic mysteries,Finally,we discuss three promising future breeding strategies utilizing the Interactome Big Data to improve crop yields and quality.展开更多
The ratio of metal：P stoichiometry was used to identify the accumulation pathways of heavy metals （V, Cr, Co, Ni, Cu, Cd, and Pb） from periphyton to snails Cipangopaludina chinensis Gray （C. chinensis） in the Bai...The ratio of metal：P stoichiometry was used to identify the accumulation pathways of heavy metals （V, Cr, Co, Ni, Cu, Cd, and Pb） from periphyton to snails Cipangopaludina chinensis Gray （C. chinensis） in the Bai River watershed. The results showed that periphyton communities were mainly composed of two types of algae, filamentous green algae and unicellular diatoms. The proportion of unicellular diatoms in the periphyton community is a key factor that influences metal accumulation in C. chinensis. The V, Cr, Co, Ni, and Cd content of C. chinensis increased steadily as the corresponding metal content of periphyton increased, but Cu and Pb in the snail did not increase in the periphyton. Mechanisms of V, Cr, and Ni accumulation were found to be related to the proportion of diatoms, while Cd and Pb accumulation were dependent on the physiological characteristics of C. chinensis. The accumulation of Cu in C. chinensis was closely related to their grazing behavior. The metal：P stoichiometry revealed that Cr, Ni, and Cd can reduce the potential ecological risks associated with increased P inputs to the ecosystem. V and Co were considered to be relatively safe, regardless of the periphyton P content. Finally, Pb may not be prone to transfer to higher trophic levels, and may pose the lowest ecological risks of the studied heavy metals, but Cu can cause potential ecological risks when eutrophication has occurred.展开更多
Within the span of five months during the Great Jubilee of the Year 2000,the Catholic Church published two documents focused on Jesus Christ:Dominus Iesus and Novo Millennio Ineunte(with emphasis in this article on it...Within the span of five months during the Great Jubilee of the Year 2000,the Catholic Church published two documents focused on Jesus Christ:Dominus Iesus and Novo Millennio Ineunte(with emphasis in this article on its second chapter).Although in various instances,both documents converge and deal with the same subject,one can observe how the perspectives and attitudes expressed in both differ in various ways.Their aim is different because Dominus Iesus was issued to oppose certain erroneous positions in the context of theories of religious pluralism,while Novo Millennio Ineunte is a pastoral reflection on the fruits of the Jubilee and the state of the community of Christ’s faithful at the turn of the last century.This article seeks to address the content of the two documents,while highlighting the differences in their style and approach.展开更多
基金This research was supported by the National Natural Science Foundation of China(92035302,31922068)the Fundamental Research Funds for the Central Universities(ZK201908)+2 种基金the Fundamental Research Funds for the Central Universities(2662020ZKPY017)the Huazhong Agricultural University Scientific&Technological Self-innovation Foundation(2015R016)the China Postdoctoral Science Foundation(2019M662666).
文摘The functional genes underlying phenotypic variation and their interactions represent“genetic mysteries”.Understanding and utilizing these genetic mysteries are key solutions for mitigating the current threats to agriculture posed by population growth and individual food preferences.Due to advances in highthroughput multi-omics technologies,we are stepping into an Interactome Big Data era that is certain to revolutionize genetic research.In this article,we provide a brief overview of current strategies to explore genetic mysteries.We then introduce the methods for constructing and analyzing the Interactome Big Data and summarize currently available interactome resources.Next,we discuss how Interactome Big Data can be used as a versatile tool to dissect genetic mysteries.We propose an integrated strategy that could revolutionize genetic research by combining Interactome Big Data with machine learning,which involves mining information hidden in Big Data to identify the genetic models or networks that control various traits,and also provide a detailed procedure for systematic dissection of genetic mysteries,Finally,we discuss three promising future breeding strategies utilizing the Interactome Big Data to improve crop yields and quality.
基金supported by the National Natural Science Foundation of China (No. 21107126)the Ministry ofWater Resources’ Special Funds for Scientific Research on Public Causes (No. 200901008)the National Water Pollution Control Program (Special Water Project) (No.2008ZX07209-010)
文摘The ratio of metal：P stoichiometry was used to identify the accumulation pathways of heavy metals （V, Cr, Co, Ni, Cu, Cd, and Pb） from periphyton to snails Cipangopaludina chinensis Gray （C. chinensis） in the Bai River watershed. The results showed that periphyton communities were mainly composed of two types of algae, filamentous green algae and unicellular diatoms. The proportion of unicellular diatoms in the periphyton community is a key factor that influences metal accumulation in C. chinensis. The V, Cr, Co, Ni, and Cd content of C. chinensis increased steadily as the corresponding metal content of periphyton increased, but Cu and Pb in the snail did not increase in the periphyton. Mechanisms of V, Cr, and Ni accumulation were found to be related to the proportion of diatoms, while Cd and Pb accumulation were dependent on the physiological characteristics of C. chinensis. The accumulation of Cu in C. chinensis was closely related to their grazing behavior. The metal：P stoichiometry revealed that Cr, Ni, and Cd can reduce the potential ecological risks associated with increased P inputs to the ecosystem. V and Co were considered to be relatively safe, regardless of the periphyton P content. Finally, Pb may not be prone to transfer to higher trophic levels, and may pose the lowest ecological risks of the studied heavy metals, but Cu can cause potential ecological risks when eutrophication has occurred.
文摘Within the span of five months during the Great Jubilee of the Year 2000,the Catholic Church published two documents focused on Jesus Christ:Dominus Iesus and Novo Millennio Ineunte(with emphasis in this article on its second chapter).Although in various instances,both documents converge and deal with the same subject,one can observe how the perspectives and attitudes expressed in both differ in various ways.Their aim is different because Dominus Iesus was issued to oppose certain erroneous positions in the context of theories of religious pluralism,while Novo Millennio Ineunte is a pastoral reflection on the fruits of the Jubilee and the state of the community of Christ’s faithful at the turn of the last century.This article seeks to address the content of the two documents,while highlighting the differences in their style and approach.
