Purpose: Mild traumatic brain injury (TBI) is common but accurate diagnosis and its clinical consequences have been a problem. Maxillofacial trauma does have an association with TBI. Neuron-specific enolase (NSE) has ...Purpose: Mild traumatic brain injury (TBI) is common but accurate diagnosis and its clinical consequences have been a problem. Maxillofacial trauma does have an association with TBI. Neuron-specific enolase (NSE) has been developed to evaluate neuronl damage. The objective of this study was to investigate the accuracy of NSE serum levels to detect mild brain injury of patients with sustained maxillofacial fractures during motor vehicle accidents. Methods: Blood samples were drawn from 40 healthy people (control group) and 48 trauma patients who has sustained isolated maxillofacial fractures and mild brain injury in motor vehicle accidents. Brain injuries were graded by Glasgow Coma Scale. In the trauma group, correlations between the NSE serum value and different facial fracture sites were also assessed. Results: The NSE serum level (mean ± SD, ng/ml) in the 48 patients with maxillofacial fractures and mild TBI was 13.12 ± 9.68, significantly higher than that measured in the healthy control group (7.72 ± 1.82, p < 0.001). The mean NSE serum level (ng/ml) in the lower part of the facial skeleton (15.44 with SD 15.34) was higher than that in the upper facial part (12.42 with SD 7.68);and the mean NSE level (ng/ml) in the middle-and lower part (11.97 with SD 5.63) was higher than in the middle part (7.88 with SD 2.64). Conclusion: An increase in NSE serum levels can be observed in patients sustained maxillofacial fractures and mild brain injury.展开更多
目的:探讨个体化心理护理干预对口腔颌面部骨折患者负性情绪及生活质量的影响,并分析其相关因素。方法:纳入2017年3月-2020年1月池州市人民医院口腔科收治的口腔颌面部骨折患者106例,按照随机数字表法分为心理护理组和常规护理组,各53...目的:探讨个体化心理护理干预对口腔颌面部骨折患者负性情绪及生活质量的影响,并分析其相关因素。方法:纳入2017年3月-2020年1月池州市人民医院口腔科收治的口腔颌面部骨折患者106例,按照随机数字表法分为心理护理组和常规护理组,各53例。心理护理组术后在常规护理基础上给予个体化心理护理方式,常规护理组术后采用常规护理方式。分别于出院时、出院3个月采用抑郁自评量表(Self-rating depression scale,SDS)和焦虑自评量表(Self-rating anxiety scale,SAS)评估患者负性情绪状况;采用健康状况调查简表(the MOS item short from health survey,SF-36)评估患者生活质量情况;以SF-36总分中位数为界值,比较两组患者临床资料,采用多因素Logistics回归方程分析影响患者生活质量的相关因素。结果:出院3个月后,心理护理组SF-36总分、情感职能、社会功能、精神健康评分高于常规护理组,SAS、SDS评分低于常规护理组,差异具有统计学意义(P<0.05)。以SF-36总分中位数为界值,对比两组患者临床资料显示,低生活质量组患者在性别、骨折严重程度、出院3个月后SAS、SDS评分、是否给予心理护理干预、面部美观度与高生活质量组比较差异具有统计学意义(P<0.05)。多因素Logistic回归分析显示,颌面部粉碎性骨折(OR=4.815)、女性(OR=4.660)、面部美观度评分越低(OR=0.866)是影响患者生活质量的独立危险因素(P<0.05);心理护理(OR=0.829)是改善患者生活质量的独立保护因素(P<0.05)。结论:个体化心理护理能够改善口腔颌面部骨折患者的负性情绪,改善生活质量;对于女性、粉碎性骨折以及对面部美观度影响较大的骨折患者的生活质量情况需要临床医生多加关注。展开更多
文摘Purpose: Mild traumatic brain injury (TBI) is common but accurate diagnosis and its clinical consequences have been a problem. Maxillofacial trauma does have an association with TBI. Neuron-specific enolase (NSE) has been developed to evaluate neuronl damage. The objective of this study was to investigate the accuracy of NSE serum levels to detect mild brain injury of patients with sustained maxillofacial fractures during motor vehicle accidents. Methods: Blood samples were drawn from 40 healthy people (control group) and 48 trauma patients who has sustained isolated maxillofacial fractures and mild brain injury in motor vehicle accidents. Brain injuries were graded by Glasgow Coma Scale. In the trauma group, correlations between the NSE serum value and different facial fracture sites were also assessed. Results: The NSE serum level (mean ± SD, ng/ml) in the 48 patients with maxillofacial fractures and mild TBI was 13.12 ± 9.68, significantly higher than that measured in the healthy control group (7.72 ± 1.82, p < 0.001). The mean NSE serum level (ng/ml) in the lower part of the facial skeleton (15.44 with SD 15.34) was higher than that in the upper facial part (12.42 with SD 7.68);and the mean NSE level (ng/ml) in the middle-and lower part (11.97 with SD 5.63) was higher than in the middle part (7.88 with SD 2.64). Conclusion: An increase in NSE serum levels can be observed in patients sustained maxillofacial fractures and mild brain injury.
文摘目的:探讨个体化心理护理干预对口腔颌面部骨折患者负性情绪及生活质量的影响,并分析其相关因素。方法:纳入2017年3月-2020年1月池州市人民医院口腔科收治的口腔颌面部骨折患者106例,按照随机数字表法分为心理护理组和常规护理组,各53例。心理护理组术后在常规护理基础上给予个体化心理护理方式,常规护理组术后采用常规护理方式。分别于出院时、出院3个月采用抑郁自评量表(Self-rating depression scale,SDS)和焦虑自评量表(Self-rating anxiety scale,SAS)评估患者负性情绪状况;采用健康状况调查简表(the MOS item short from health survey,SF-36)评估患者生活质量情况;以SF-36总分中位数为界值,比较两组患者临床资料,采用多因素Logistics回归方程分析影响患者生活质量的相关因素。结果:出院3个月后,心理护理组SF-36总分、情感职能、社会功能、精神健康评分高于常规护理组,SAS、SDS评分低于常规护理组,差异具有统计学意义(P<0.05)。以SF-36总分中位数为界值,对比两组患者临床资料显示,低生活质量组患者在性别、骨折严重程度、出院3个月后SAS、SDS评分、是否给予心理护理干预、面部美观度与高生活质量组比较差异具有统计学意义(P<0.05)。多因素Logistic回归分析显示,颌面部粉碎性骨折(OR=4.815)、女性(OR=4.660)、面部美观度评分越低(OR=0.866)是影响患者生活质量的独立危险因素(P<0.05);心理护理(OR=0.829)是改善患者生活质量的独立保护因素(P<0.05)。结论:个体化心理护理能够改善口腔颌面部骨折患者的负性情绪,改善生活质量;对于女性、粉碎性骨折以及对面部美观度影响较大的骨折患者的生活质量情况需要临床医生多加关注。
