背景:近些年,肝脏类器官的发展使其成为国际肝病研究领域的热点,但目前仍未有文献对其进行文献计量学分析。目的:基于文献计量学与可视化分析探索近20年肝脏类器官的热点趋势。方法:从Web of Science(科学网,WOS)核心合集中检索2002-01-...背景:近些年,肝脏类器官的发展使其成为国际肝病研究领域的热点,但目前仍未有文献对其进行文献计量学分析。目的:基于文献计量学与可视化分析探索近20年肝脏类器官的热点趋势。方法:从Web of Science(科学网,WOS)核心合集中检索2002-01-01/2022-11-12肝脏类器官的相关文献,运行Origin、Office和CiteSpace软件进行文献计量与可视化分析,通过生成图表的方式来统计分析文献的年发文量、国家、机构、作者、期刊和关键词等内容。结果与结论:肝脏类器官研究领域近20年的发文量、被引频次、加入研究的机构和人员总体呈现上升趋势,说明该领域发展迅速关注度也逐渐升高。在该领域中,美国的发文量最多、影响力最强,虽然投入大量的时间与精力,但是在众多研究机构中美国单个研究机构的发文量并非最高;中国发文量仅次于美国,中国科学院和复旦大学是国内发文量最多的机构。荷兰乌得勒支大学是发文量最多的机构,发文量最高的作者是Clevers H,共引频次最高的文章是“Long-term culture of genome-stable bipotent stem cells from adult human liver”,分子学、生物学、免疫学是肝脏类器官研究的主流学科,出现次数最高的关键词包括stem cell(干细胞)、in vitro(体外)和culture(培养),肝脏类器官领域的研究热点主要集中在体外干细胞三维培养、分化及基因表达。展开更多
干法后处理技术是国际上公认的可实现核燃料闭式循环的技术之一。在过去的十几年中,中国科学院上海应用物理研究所(Shanghai Institute of Applied Physics,Chinese Academy of Sciences,SINAP)一直专注于干法后处理技术的开发。热室及...干法后处理技术是国际上公认的可实现核燃料闭式循环的技术之一。在过去的十几年中,中国科学院上海应用物理研究所(Shanghai Institute of Applied Physics,Chinese Academy of Sciences,SINAP)一直专注于干法后处理技术的开发。热室及热室内的远程操作系统是实施乏燃料干法后处理工艺的重要技术保障,也是SINAP在乏燃料后处理领域内主要的研究方向之一。本研究以氟化挥发、减压蒸馏两项干法技术的工艺设备为研究对象,开展了热室内设备的远程操作评估和干法工艺验证实验。实验结果表明:在热室内工艺设备布置合理的基础上,工艺单元操作中,装料和出料的工作负荷较大,其负荷值在2.0以上;在两种工艺实验过程中,开/关操作的负荷值均较小,分别为0.07和0.14;螺栓旋紧/旋松、装料和出料等耗时较长,操作效率低;热室内干法工艺验证实验中,熔盐体系铀氟化分离工艺实现了铀转化率为99.8%,铀产物回收率大于99%;熔盐减压蒸馏工艺实现了较高熔盐蒸发量和100%熔盐蒸馏回收率。本研究工作将为实现热室内真实乏燃料的干法后处理提供重要参考依据。展开更多
BACKGROUND Pleomorphic leiomyosarcomas make up around 8.6%of all leiomyosarcomas.They behave aggressively and often have poor prognoses.They can affect the gastrointestinal tract and retroperitoneum.To date,pleomorphi...BACKGROUND Pleomorphic leiomyosarcomas make up around 8.6%of all leiomyosarcomas.They behave aggressively and often have poor prognoses.They can affect the gastrointestinal tract and retroperitoneum.To date,pleomorphic leiomyosarcoma involving the mesocolon have been reported in nine patients.CASE SUMMARY The patient was a 44-year-old man with a history of pleomorphic leiomyosarcoma of the left maxilla with metastasis to the lung and liver.His most recent positron emission tomography-computed tomography(PET-CT)scan showed uptake in the ascending and transverse colons.A colonoscopy revealed a 5.0 cm×3.5 cm×3.0 cm pedunculated polyp in the ascending colon.The polyp was removed using hot snare polypectomy technique and retrieved with Rothnet.Histopathologic examination of the polyp showed a metastatic pleomorphic leiomyosarcoma.CONCLUSION Uptake(s)on PET-CT in a patient with pleomorphic leiomyosarcoma should raise suspicion for metastasis.展开更多
How to effectively utilize the energy of the broad spectrum of sunlight is one of the basic problems in the research of tandem solar cells. Due to their size effect, quantum confinement effect and coupling effect, col...How to effectively utilize the energy of the broad spectrum of sunlight is one of the basic problems in the research of tandem solar cells. Due to their size effect, quantum confinement effect and coupling effect, colloidal quantum dots(QDs) exhibit new physical properties that bulk materials don’t possess.CdX(X = Se, S, etc.) and Pb X(X = Se, S, etc.) QDs prepared by hot-injection methods have been widely studied in the areas of photovolitaic devices. However, the surfactants surrounding QDs seriously hinder the charge transport of QDs based solar cells. Therefore, how to fabricate high-performance tandem solar cells via ligands engineering has become a major challenge. In this paper, the latest progress of colloidal QDs in the research of all-inorganic tandem solar cells was summarized. Firstly, the improvement of QDs surface ligands and the optimization of ligands engineering were discussed, and the control of the physical properties of QDs films were realized. From the aspects of colloidal QDs, ligand engineering, and solar cell preparation, the future development direction of colloidal QDs solar cells was proposed, providing technical guidances for the preparation of low-cost and high-efficiency nanocrystalline solar cells.展开更多
文摘背景:近些年,肝脏类器官的发展使其成为国际肝病研究领域的热点,但目前仍未有文献对其进行文献计量学分析。目的:基于文献计量学与可视化分析探索近20年肝脏类器官的热点趋势。方法:从Web of Science(科学网,WOS)核心合集中检索2002-01-01/2022-11-12肝脏类器官的相关文献,运行Origin、Office和CiteSpace软件进行文献计量与可视化分析,通过生成图表的方式来统计分析文献的年发文量、国家、机构、作者、期刊和关键词等内容。结果与结论:肝脏类器官研究领域近20年的发文量、被引频次、加入研究的机构和人员总体呈现上升趋势,说明该领域发展迅速关注度也逐渐升高。在该领域中,美国的发文量最多、影响力最强,虽然投入大量的时间与精力,但是在众多研究机构中美国单个研究机构的发文量并非最高;中国发文量仅次于美国,中国科学院和复旦大学是国内发文量最多的机构。荷兰乌得勒支大学是发文量最多的机构,发文量最高的作者是Clevers H,共引频次最高的文章是“Long-term culture of genome-stable bipotent stem cells from adult human liver”,分子学、生物学、免疫学是肝脏类器官研究的主流学科,出现次数最高的关键词包括stem cell(干细胞)、in vitro(体外)和culture(培养),肝脏类器官领域的研究热点主要集中在体外干细胞三维培养、分化及基因表达。
文摘干法后处理技术是国际上公认的可实现核燃料闭式循环的技术之一。在过去的十几年中,中国科学院上海应用物理研究所(Shanghai Institute of Applied Physics,Chinese Academy of Sciences,SINAP)一直专注于干法后处理技术的开发。热室及热室内的远程操作系统是实施乏燃料干法后处理工艺的重要技术保障,也是SINAP在乏燃料后处理领域内主要的研究方向之一。本研究以氟化挥发、减压蒸馏两项干法技术的工艺设备为研究对象,开展了热室内设备的远程操作评估和干法工艺验证实验。实验结果表明:在热室内工艺设备布置合理的基础上,工艺单元操作中,装料和出料的工作负荷较大,其负荷值在2.0以上;在两种工艺实验过程中,开/关操作的负荷值均较小,分别为0.07和0.14;螺栓旋紧/旋松、装料和出料等耗时较长,操作效率低;热室内干法工艺验证实验中,熔盐体系铀氟化分离工艺实现了铀转化率为99.8%,铀产物回收率大于99%;熔盐减压蒸馏工艺实现了较高熔盐蒸发量和100%熔盐蒸馏回收率。本研究工作将为实现热室内真实乏燃料的干法后处理提供重要参考依据。
文摘BACKGROUND Pleomorphic leiomyosarcomas make up around 8.6%of all leiomyosarcomas.They behave aggressively and often have poor prognoses.They can affect the gastrointestinal tract and retroperitoneum.To date,pleomorphic leiomyosarcoma involving the mesocolon have been reported in nine patients.CASE SUMMARY The patient was a 44-year-old man with a history of pleomorphic leiomyosarcoma of the left maxilla with metastasis to the lung and liver.His most recent positron emission tomography-computed tomography(PET-CT)scan showed uptake in the ascending and transverse colons.A colonoscopy revealed a 5.0 cm×3.5 cm×3.0 cm pedunculated polyp in the ascending colon.The polyp was removed using hot snare polypectomy technique and retrieved with Rothnet.Histopathologic examination of the polyp showed a metastatic pleomorphic leiomyosarcoma.CONCLUSION Uptake(s)on PET-CT in a patient with pleomorphic leiomyosarcoma should raise suspicion for metastasis.
基金the National Natural Science Foundation of China(No.51976081)。
文摘How to effectively utilize the energy of the broad spectrum of sunlight is one of the basic problems in the research of tandem solar cells. Due to their size effect, quantum confinement effect and coupling effect, colloidal quantum dots(QDs) exhibit new physical properties that bulk materials don’t possess.CdX(X = Se, S, etc.) and Pb X(X = Se, S, etc.) QDs prepared by hot-injection methods have been widely studied in the areas of photovolitaic devices. However, the surfactants surrounding QDs seriously hinder the charge transport of QDs based solar cells. Therefore, how to fabricate high-performance tandem solar cells via ligands engineering has become a major challenge. In this paper, the latest progress of colloidal QDs in the research of all-inorganic tandem solar cells was summarized. Firstly, the improvement of QDs surface ligands and the optimization of ligands engineering were discussed, and the control of the physical properties of QDs films were realized. From the aspects of colloidal QDs, ligand engineering, and solar cell preparation, the future development direction of colloidal QDs solar cells was proposed, providing technical guidances for the preparation of low-cost and high-efficiency nanocrystalline solar cells.
