Tear film,the outermost layer of the eye,is a complex and dynamic structure responsible for tear production.The tear film lipid layer is a vital component of the tear film that provides a smooth optical surface for th...Tear film,the outermost layer of the eye,is a complex and dynamic structure responsible for tear production.The tear film lipid layer is a vital component of the tear film that provides a smooth optical surface for the cornea and wetting the ocular surface.Dry eye syndrome(DES)is a symptomatic disease caused by reduced tear production,poor tear quality,or excessive evaporation.Its diagnosis is a difficult task due to its multifactorial etiology.Out of several clinical tests available,the evaluation of the interference patterns of the tear film lipid layer forms a potential tool for DES diagnosis.An instrument known as Tearscope Plus allows the rapid assessment of the lipid layer.A grading scale composed of five categories is used to classify lipid layer patterns.The reported work proposes the design of an automatic system employing light weight convolutional neural networks(CNN)and nature inspired optimization techniques to assess the tear film lipid layer patterns by interpreting the images acquired with the Tearscope Plus.The designed framework achieves promising results compared with the existing state-of-the-art techniques.展开更多
目的研究中药明目五子汤联合针刺治疗肝肾阴虚型水样液缺乏性干眼症的临床效果。方法选取2017年1月—2020年7月浙江中医药大学附属宁波市中医院接收的60例肝肾阴虚型干眼症患者,随机分为A组和B组,每组30例。A组采用中药明目五子汤治疗,...目的研究中药明目五子汤联合针刺治疗肝肾阴虚型水样液缺乏性干眼症的临床效果。方法选取2017年1月—2020年7月浙江中医药大学附属宁波市中医院接收的60例肝肾阴虚型干眼症患者,随机分为A组和B组,每组30例。A组采用中药明目五子汤治疗,B组在A组的基础上给予针刺疗法。比较2组患者的泪液分泌测试(Schirmer I test,SIT)、泪膜破裂时间(Tear film break up time,BUT)、白细胞介素-6(Interleukin-6,IL-6)、干眼症积分及角膜染色评分。结果B组治疗后的SIT、BUT优于A组,IL-6水平和干眼症积分低于A组,差异均有统计学意义(P<0.05)。结论中药明目五子汤联合针刺治疗肝肾阴虚型干眼症,能改善患者的内膜稳定性和干眼症症状,值得临床推广。展开更多
文摘Tear film,the outermost layer of the eye,is a complex and dynamic structure responsible for tear production.The tear film lipid layer is a vital component of the tear film that provides a smooth optical surface for the cornea and wetting the ocular surface.Dry eye syndrome(DES)is a symptomatic disease caused by reduced tear production,poor tear quality,or excessive evaporation.Its diagnosis is a difficult task due to its multifactorial etiology.Out of several clinical tests available,the evaluation of the interference patterns of the tear film lipid layer forms a potential tool for DES diagnosis.An instrument known as Tearscope Plus allows the rapid assessment of the lipid layer.A grading scale composed of five categories is used to classify lipid layer patterns.The reported work proposes the design of an automatic system employing light weight convolutional neural networks(CNN)and nature inspired optimization techniques to assess the tear film lipid layer patterns by interpreting the images acquired with the Tearscope Plus.The designed framework achieves promising results compared with the existing state-of-the-art techniques.
文摘目的研究中药明目五子汤联合针刺治疗肝肾阴虚型水样液缺乏性干眼症的临床效果。方法选取2017年1月—2020年7月浙江中医药大学附属宁波市中医院接收的60例肝肾阴虚型干眼症患者,随机分为A组和B组,每组30例。A组采用中药明目五子汤治疗,B组在A组的基础上给予针刺疗法。比较2组患者的泪液分泌测试(Schirmer I test,SIT)、泪膜破裂时间(Tear film break up time,BUT)、白细胞介素-6(Interleukin-6,IL-6)、干眼症积分及角膜染色评分。结果B组治疗后的SIT、BUT优于A组,IL-6水平和干眼症积分低于A组,差异均有统计学意义(P<0.05)。结论中药明目五子汤联合针刺治疗肝肾阴虚型干眼症,能改善患者的内膜稳定性和干眼症症状,值得临床推广。
