Background/Aim: Telogen effluvium (TE) is a scalp disorder characterized by the thinning or shedding of hair resulting from the early entry of hair in the telogen phase. Nigella sativa (NS) is a dicotyledonous belongi...Background/Aim: Telogen effluvium (TE) is a scalp disorder characterized by the thinning or shedding of hair resulting from the early entry of hair in the telogen phase. Nigella sativa (NS) is a dicotyledonous belonging to the Ranunculacae family. It has been shown that its major constituent, tymoquinon (TQ), exerts anti-oxidant and anti-inflammatory effects by inhibiting pro-inflammatory mediators, such as cyclooxygenase and prostaglandin D2. The aim of this study is to evaluate the efficacy of NS essential oil as a potential treatment for TE, a pathology characterized by a significant inflammatory component. Study Design/Methods: Twenty patients affected by TE for this double-blind, placebo controlled and randomized study were enrolled. Ten of these patients were treated with a scalp lotion containing 0.5% NS, daily for 3 months, while the other ten patients were treated with placebo daily for 3 months. Videodermatoscopic analysis (Trichoscan Dermoscope Fotofinder?) and evaluation of three independent dermatologists were performed before treatment (T0), after 3 months of treatment (T3) and at the 6 months follow-up (T6). Results: The results showed a significant improvement in 70% of patients treated with NS. Videodermatoscopic analysis showed a significant increment of hair density and hair thickness in patients treated with NS. NS was also able to reduce the inflammation observed in the majority of patients affected by TE. Conclusions: The results of this study suggest that NS can be considered potentially useful for the treatment of TE.展开更多
[Objective] The paper was to characterize hair density by changes in hair thickness under certain pressure.[Method] Tile effects of weight of thickness tester and wafer urea at the hottom of presser foot on measuremen...[Objective] The paper was to characterize hair density by changes in hair thickness under certain pressure.[Method] Tile effects of weight of thickness tester and wafer urea at the hottom of presser foot on measurement results were studied, and the optimal measuring weight and wafer diameter was determined. The measurement results of hair thickness under the ahove condition were compared with the results of manual counting. Meanwhile, the effects of hair length and hair fineness on hair density were analyzed.[Result] The hair density obtained by manual count- ing had consistent change trend with the hair thickness measured under certain conditions. If the length and fineness of hairs were introduced for modification, the correlation between hair thickness and hair density would be better. There were little changes in hair length and finelless of rex rabbit, and their effects on hair thickness could be ignored under general condition. [Conclusion] It is completely feasible to characterize hair den- sity of rex rabbit by hair thickness under pressure.展开更多
The implantable artificial hair was prepared by grafting collagen on the surface of poly(ethylene terephthalate)(PET)to improve its biocompatibility.Acrylic acid(AAc)was used to modify the surface properties of PET fi...The implantable artificial hair was prepared by grafting collagen on the surface of poly(ethylene terephthalate)(PET)to improve its biocompatibility.Acrylic acid(AAc)was used to modify the surface properties of PET firstly,and then collagen was grafted on the PET-AAc surface.The concentration of collagen solution was discussed to graft more collagen on PET surface.Composites were well characterized by scanning electron microscopy(SEM),Fourier transform infrared spectroscopy(FTIR)and X-ray photoelectron spectroscopy(XPS).SEM indicated that collagen with about 3.07μm thickness was coated on PET surface when the concentration of collagen solution was 1.0 mg/m L.FTIR and XPS showed AAc and collagen were both on the surface of PET monofilaments.The optimized concentration of collagen solution was 1.0 mg/m L,resulting in the most grafting density of 3.46μg/cm^(2).It can be concluded that a large amount of collagen is coated on PET surface.展开更多
文摘Background/Aim: Telogen effluvium (TE) is a scalp disorder characterized by the thinning or shedding of hair resulting from the early entry of hair in the telogen phase. Nigella sativa (NS) is a dicotyledonous belonging to the Ranunculacae family. It has been shown that its major constituent, tymoquinon (TQ), exerts anti-oxidant and anti-inflammatory effects by inhibiting pro-inflammatory mediators, such as cyclooxygenase and prostaglandin D2. The aim of this study is to evaluate the efficacy of NS essential oil as a potential treatment for TE, a pathology characterized by a significant inflammatory component. Study Design/Methods: Twenty patients affected by TE for this double-blind, placebo controlled and randomized study were enrolled. Ten of these patients were treated with a scalp lotion containing 0.5% NS, daily for 3 months, while the other ten patients were treated with placebo daily for 3 months. Videodermatoscopic analysis (Trichoscan Dermoscope Fotofinder?) and evaluation of three independent dermatologists were performed before treatment (T0), after 3 months of treatment (T3) and at the 6 months follow-up (T6). Results: The results showed a significant improvement in 70% of patients treated with NS. Videodermatoscopic analysis showed a significant increment of hair density and hair thickness in patients treated with NS. NS was also able to reduce the inflammation observed in the majority of patients affected by TE. Conclusions: The results of this study suggest that NS can be considered potentially useful for the treatment of TE.
基金Supported by Special Fund of China Agricultural Industry Research System(CARS-44-D-3)the Key Project of Sichuan Province(2016 NZ0002)
文摘[Objective] The paper was to characterize hair density by changes in hair thickness under certain pressure.[Method] Tile effects of weight of thickness tester and wafer urea at the hottom of presser foot on measurement results were studied, and the optimal measuring weight and wafer diameter was determined. The measurement results of hair thickness under the ahove condition were compared with the results of manual counting. Meanwhile, the effects of hair length and hair fineness on hair density were analyzed.[Result] The hair density obtained by manual count- ing had consistent change trend with the hair thickness measured under certain conditions. If the length and fineness of hairs were introduced for modification, the correlation between hair thickness and hair density would be better. There were little changes in hair length and finelless of rex rabbit, and their effects on hair thickness could be ignored under general condition. [Conclusion] It is completely feasible to characterize hair den- sity of rex rabbit by hair thickness under pressure.
基金Beijing Municipal Commission of Science and Technology Plan Projects,China(No.KYTG02170206/016)Open Project of Beijing Key Laboratory of Clothing Materials R&D and Assessment,China(No.KYTG02170205)
文摘The implantable artificial hair was prepared by grafting collagen on the surface of poly(ethylene terephthalate)(PET)to improve its biocompatibility.Acrylic acid(AAc)was used to modify the surface properties of PET firstly,and then collagen was grafted on the PET-AAc surface.The concentration of collagen solution was discussed to graft more collagen on PET surface.Composites were well characterized by scanning electron microscopy(SEM),Fourier transform infrared spectroscopy(FTIR)and X-ray photoelectron spectroscopy(XPS).SEM indicated that collagen with about 3.07μm thickness was coated on PET surface when the concentration of collagen solution was 1.0 mg/m L.FTIR and XPS showed AAc and collagen were both on the surface of PET monofilaments.The optimized concentration of collagen solution was 1.0 mg/m L,resulting in the most grafting density of 3.46μg/cm^(2).It can be concluded that a large amount of collagen is coated on PET surface.
