目的:比较莫司类药物洗脱支架(LES)与紫杉醇洗脱支架(PES)在冠状动脉小血管病变患者中的疗效。方法:通过PubMed、Web of Science、ClinicalTrials、中国生物医学文献数据库、中国知网、万方数据和维普数据库对与本次研究主题相关的文献...目的:比较莫司类药物洗脱支架(LES)与紫杉醇洗脱支架(PES)在冠状动脉小血管病变患者中的疗效。方法:通过PubMed、Web of Science、ClinicalTrials、中国生物医学文献数据库、中国知网、万方数据和维普数据库对与本次研究主题相关的文献进行检索,对纳入的文献进行方法学质量评价。采用RevMan 5.2及Stata 14.0软件进行相关的统计学分析。结果:八项研究共4738例患者纳入此研究。与PES比较,植入LES能减少主要心血管不良事件(RR=0.64,95%CI:0.53~0.77,Z=4.59,P<0.01)、心肌梗死(RR=0.61,95%CI:0.45~0.82,Z=3.24,P<0.01)、支架内血栓(RR=0.22,95%CI:0.13~0.37,Z=5.71,P<0.01)以及靶病变血运重建(RR=0.56,95%CI:0.44~0.71,Z=4.72,P<0.01)的发生率。与PES比较,LES不能减少心因性死亡(RR=1.08,95%CI:0.62~1.88,Z=0.26,P>0.05)和靶血管血运重建事件的发生率(RR=0.80,95%CI:0.45~1.44,Z=0.74,P>0.05)。结论:对于冠状动脉小血管病变行经皮冠脉介入支架植入术的患者,LES较PES有更好的长期疗效,可作为该类患者的首选支架。展开更多
In the present paper, the therapeutic effects of point-injection and electro-acupuncture(EA) were compared in 100 patients of coronary heart disease with abnormal increases of indexes ofblood rheology. Results indicat...In the present paper, the therapeutic effects of point-injection and electro-acupuncture(EA) were compared in 100 patients of coronary heart disease with abnormal increases of indexes ofblood rheology. Results indicated that after one therapeutic course, the increases of indexes of bloodrheology were reduced in Geshu-ligustrazine group, Geshu-saline group, Geshu-EA group and Feishu-ligustrazine group (P【0. 05 - 0. 01 ) and there was no this action in Feishu-EA group. Among them,the Geshu-EA group had the best therapeutic effect.展开更多
文摘目的:比较莫司类药物洗脱支架(LES)与紫杉醇洗脱支架(PES)在冠状动脉小血管病变患者中的疗效。方法:通过PubMed、Web of Science、ClinicalTrials、中国生物医学文献数据库、中国知网、万方数据和维普数据库对与本次研究主题相关的文献进行检索,对纳入的文献进行方法学质量评价。采用RevMan 5.2及Stata 14.0软件进行相关的统计学分析。结果:八项研究共4738例患者纳入此研究。与PES比较,植入LES能减少主要心血管不良事件(RR=0.64,95%CI:0.53~0.77,Z=4.59,P<0.01)、心肌梗死(RR=0.61,95%CI:0.45~0.82,Z=3.24,P<0.01)、支架内血栓(RR=0.22,95%CI:0.13~0.37,Z=5.71,P<0.01)以及靶病变血运重建(RR=0.56,95%CI:0.44~0.71,Z=4.72,P<0.01)的发生率。与PES比较,LES不能减少心因性死亡(RR=1.08,95%CI:0.62~1.88,Z=0.26,P>0.05)和靶血管血运重建事件的发生率(RR=0.80,95%CI:0.45~1.44,Z=0.74,P>0.05)。结论:对于冠状动脉小血管病变行经皮冠脉介入支架植入术的患者,LES较PES有更好的长期疗效,可作为该类患者的首选支架。
文摘In the present paper, the therapeutic effects of point-injection and electro-acupuncture(EA) were compared in 100 patients of coronary heart disease with abnormal increases of indexes ofblood rheology. Results indicated that after one therapeutic course, the increases of indexes of bloodrheology were reduced in Geshu-ligustrazine group, Geshu-saline group, Geshu-EA group and Feishu-ligustrazine group (P【0. 05 - 0. 01 ) and there was no this action in Feishu-EA group. Among them,the Geshu-EA group had the best therapeutic effect.
