The layered charges were calculated by means of constructing the complete structure of Tl Ba Ca Cu O superconductor. The weak link between Cu O and Ba O, or between Cu O and Tl O or Ba O or Tl O layers i...The layered charges were calculated by means of constructing the complete structure of Tl Ba Ca Cu O superconductor. The weak link between Cu O and Ba O, or between Cu O and Tl O or Ba O or Tl O layers is explained with the aid of the charge of limited layer unit calculated from the values of ions obtained, in addition to the possibility of forming charges fluctuation, which depends on the π coordination covalent bond on Cu O plane and O Tl O structure. The possible chemical tight bonding orbitals are in accordance with those of other superconductors obtained by quantum theoretical method, which occur at Cu 3d (x 2-y 2) and O 2p x,y . The valence band composed of Cu 3d and O 2p orbital energy levels is obviously an energy band of conduction. The ordered charge on layers is the main reason that raises T c of superconductors. The difference of electronic structure of ab plane and c axis leads to the anisotropy properties.展开更多
Moderate prosperity is a social ideal for which the Chinese people have been striving for thousands of years.After the founding of the People's Republic of China,and especially since the reform and opening-up poli...Moderate prosperity is a social ideal for which the Chinese people have been striving for thousands of years.After the founding of the People's Republic of China,and especially since the reform and opening-up policy was implemented in the late 1970s,the Communist Party of China deepened its understanding of the laws governing the building a moderate prosperous society in practice and wrought brilliant achievements in completing a moderate prosperous society in all respects.Completing such a society is a key step in realizing the Chinese dream of national rejuvenation,making scientific socialism radiate strong vitality in the 21st century and greatly expanding the way developing countries modernize.The great practice of completing a moderately prosperous society in all respects has accumulated precious experience for building a modern socialist country in all respects.展开更多
Background:Clear cell renal carcinoma(ccRCC)is notorious for its highly unfavorable prognosis,closely related to immune cell infiltration(ICI).MYB Proto-Oncogene Like 2(MYBL2)is elevated in multiple types of human can...Background:Clear cell renal carcinoma(ccRCC)is notorious for its highly unfavorable prognosis,closely related to immune cell infiltration(ICI).MYB Proto-Oncogene Like 2(MYBL2)is elevated in multiple types of human cancer and is recognized as a crucial role in tumorigenesis.In the present study,we aimed to determine the roles of MYBL2 in the prognostic outcomes of ccRCC.Methods:We analyzed the GSE100666 dataset from the Gene Expression Omnibus(GEO)database and found that the expression of MYBL2 was significantly higher in ccRCC subjects than in normal controls.Next,RNA sequencing data related to ccRCC were retrieved from The Cancer Genome Atlas(TCGA)database and the levels of MYBL2 were compared between tumor and peri-tumor tissues.The correlation between MYBL2 and clinicopathological parameters was assessed by logistic analysis.The Kaplan-Meier method,Cox-regression analysis,and nomograms,were applied to investigate the potential clinical benefits of MYBL2 in ccRCC.We also evaluated the correlation between MYBL2 and immune cell infiltration with a single-sample gene set enrichment analysis(ssGSEA).The association between MYBL2 and immune checkpoints was determined via the TIMER and TISIDB databases.Finally,correlation analysis was conducted to predict upstream non-coding RNAs(ncRNAs)regulating MYBL2,and a completing endogenous RNA(ceRNA)network was constructed to visualize the long non-coding RNAs(lncRNAs)-microRNAs(miRNAs)-MYBL2 axis in ccRCC.Finally,further analysis of upstream lncRNAs was carried out to validate the accuracy of the network.Results:MYBL2 was significantly over-expressed in ccRCC(P<0.001).High levels of MYBL2 expression in ccRCC correlated with a worse T stage,a more advanced N stage,a higher M stage,a more deleterious pathological stage,and higher histological grades.MYBL2 was identified as a risk factor for disease-specific survival(hazard ratio(HR)=2.73,P<0.001),overall survival(HR=1.91,P<0.001),and progression-free interval(HR=2.03,P<0.001).MYBL2 also positively associated with multiple type展开更多
The past 40 years has seen the remarkable history of the building of not only socialism with Chinese characteristics but also a moderately prosperous society by the Chinese people led by the Communist Party of China.B...The past 40 years has seen the remarkable history of the building of not only socialism with Chinese characteristics but also a moderately prosperous society by the Chinese people led by the Communist Party of China.By 2020,China will have finished building a moderately prosperous society in all respects and realized the second strategic objective of the rejuvenation of the Chinese nation.展开更多
As we review the historical process of completing the building a moderately prosperous society in all respects,the rule of law through the right to education,which has played a leading and guaranteeing role in this pr...As we review the historical process of completing the building a moderately prosperous society in all respects,the rule of law through the right to education,which has played a leading and guaranteeing role in this process,has not only made great achievements,but also set the direction and path for the development of the education system and unleashed education’s momentum in driving social development.The rule of law through the right to education has been established and developed during the great practice of reform and opening-up.After we achieve the goal of realizing all-round moderate prosperity,it is necessary to straighten out the internal mechanisms concerning its next-step development and codify educational laws in order to further promote human rights progress in China.展开更多
文摘The layered charges were calculated by means of constructing the complete structure of Tl Ba Ca Cu O superconductor. The weak link between Cu O and Ba O, or between Cu O and Tl O or Ba O or Tl O layers is explained with the aid of the charge of limited layer unit calculated from the values of ions obtained, in addition to the possibility of forming charges fluctuation, which depends on the π coordination covalent bond on Cu O plane and O Tl O structure. The possible chemical tight bonding orbitals are in accordance with those of other superconductors obtained by quantum theoretical method, which occur at Cu 3d (x 2-y 2) and O 2p x,y . The valence band composed of Cu 3d and O 2p orbital energy levels is obviously an energy band of conduction. The ordered charge on layers is the main reason that raises T c of superconductors. The difference of electronic structure of ab plane and c axis leads to the anisotropy properties.
文摘Moderate prosperity is a social ideal for which the Chinese people have been striving for thousands of years.After the founding of the People's Republic of China,and especially since the reform and opening-up policy was implemented in the late 1970s,the Communist Party of China deepened its understanding of the laws governing the building a moderate prosperous society in practice and wrought brilliant achievements in completing a moderate prosperous society in all respects.Completing such a society is a key step in realizing the Chinese dream of national rejuvenation,making scientific socialism radiate strong vitality in the 21st century and greatly expanding the way developing countries modernize.The great practice of completing a moderately prosperous society in all respects has accumulated precious experience for building a modern socialist country in all respects.
基金supported by the Key Medical Research Projects of Jiangsu Commission of Health(ID:2022013).
文摘Background:Clear cell renal carcinoma(ccRCC)is notorious for its highly unfavorable prognosis,closely related to immune cell infiltration(ICI).MYB Proto-Oncogene Like 2(MYBL2)is elevated in multiple types of human cancer and is recognized as a crucial role in tumorigenesis.In the present study,we aimed to determine the roles of MYBL2 in the prognostic outcomes of ccRCC.Methods:We analyzed the GSE100666 dataset from the Gene Expression Omnibus(GEO)database and found that the expression of MYBL2 was significantly higher in ccRCC subjects than in normal controls.Next,RNA sequencing data related to ccRCC were retrieved from The Cancer Genome Atlas(TCGA)database and the levels of MYBL2 were compared between tumor and peri-tumor tissues.The correlation between MYBL2 and clinicopathological parameters was assessed by logistic analysis.The Kaplan-Meier method,Cox-regression analysis,and nomograms,were applied to investigate the potential clinical benefits of MYBL2 in ccRCC.We also evaluated the correlation between MYBL2 and immune cell infiltration with a single-sample gene set enrichment analysis(ssGSEA).The association between MYBL2 and immune checkpoints was determined via the TIMER and TISIDB databases.Finally,correlation analysis was conducted to predict upstream non-coding RNAs(ncRNAs)regulating MYBL2,and a completing endogenous RNA(ceRNA)network was constructed to visualize the long non-coding RNAs(lncRNAs)-microRNAs(miRNAs)-MYBL2 axis in ccRCC.Finally,further analysis of upstream lncRNAs was carried out to validate the accuracy of the network.Results:MYBL2 was significantly over-expressed in ccRCC(P<0.001).High levels of MYBL2 expression in ccRCC correlated with a worse T stage,a more advanced N stage,a higher M stage,a more deleterious pathological stage,and higher histological grades.MYBL2 was identified as a risk factor for disease-specific survival(hazard ratio(HR)=2.73,P<0.001),overall survival(HR=1.91,P<0.001),and progression-free interval(HR=2.03,P<0.001).MYBL2 also positively associated with multiple type
文摘The past 40 years has seen the remarkable history of the building of not only socialism with Chinese characteristics but also a moderately prosperous society by the Chinese people led by the Communist Party of China.By 2020,China will have finished building a moderately prosperous society in all respects and realized the second strategic objective of the rejuvenation of the Chinese nation.
基金a phased result of the“Institute for Education Law of the Ministry of Education”,a first-class liberal arts development program(think tank development and social service capability improvement program)of the universitythe“study on the refinement of socialist core values and legal system for education”,a major project of the National Social Science Fund of China(project number:19VHJ010)
文摘As we review the historical process of completing the building a moderately prosperous society in all respects,the rule of law through the right to education,which has played a leading and guaranteeing role in this process,has not only made great achievements,but also set the direction and path for the development of the education system and unleashed education’s momentum in driving social development.The rule of law through the right to education has been established and developed during the great practice of reform and opening-up.After we achieve the goal of realizing all-round moderate prosperity,it is necessary to straighten out the internal mechanisms concerning its next-step development and codify educational laws in order to further promote human rights progress in China.
