The traditional roles of a university are teaching and research with the aim of developing society and contributing positively to the national economic development by producing skilled and well-tutored graduates. Howe...The traditional roles of a university are teaching and research with the aim of developing society and contributing positively to the national economic development by producing skilled and well-tutored graduates. However, recruitments by these higher institutions are too reliant on the eligibility provided by Resumes of candidates, while neglecting their suitability drawn from their research activity and publications online. This study identifies insights in recruitment trends in higher institutions of learning and uses Artificial Intelligence to produce a more rounded and balanced decision-making process that caters for both eligibility and suitability. The methodology employs the machine learning process using the Multinomial Naïve Bayes for training the model as well as the Vader sentiment analyzer for accuracy and testing. The datasets used contained Resume instances as well as author publication information. The results show a score of 83.9% for the model as well as a sentiment analysis score of 1, indicating an overall positive score. The results show that sentiment analysis can help educational institutions in improving their recruitment models and attracting more suitable candidates for such roles.展开更多
Grain size plays a significant role in rice,starting from affecting yield to consumer preference,which is the driving force for deep investigation and improvement of grain size characters.Quantitative inheritance make...Grain size plays a significant role in rice,starting from affecting yield to consumer preference,which is the driving force for deep investigation and improvement of grain size characters.Quantitative inheritance makes these traits complex to breed on account of several alleles contributing to the complete trait expression.We employed genome-wide association study in an association panel of 88 rice genotypes using 142 new candidate gene based SSR(cgSSR)markers,derived from yield-related candidate genes,with the efficient mixed-model association coupled mixed linear model for dissecting complete genetic control of grain size traits.A total of 10 significant associations were identified for four grain size-related characters(grain weight,grain length,grain width,and length-width ratio).Among the identified associations,seven marker trait associations explain more than 10%of the phenotypic variation,indicating major putative QTLs for respective traits.The allelic variations at genes OsBC1L4,SHO1 and OsD2 showed association between 1000-grain weight and grain width,1000-grain weight and grain length,and grain width and length-width ratio,respectively.The cgSSR markers,associated with corresponding traits,can be utilized for direct allelic selection,while other significantly associated cgSSRs may be utilized for allelic accumulation in the breeding programs or grain size improvement.The new cgSSR markers associated with grain size related characters have a significant impact on practical plant breeding to increase the number of causative alleles for these traits through marker aided rice breeding programs.展开更多
To search for genes associated with migratory phenotypes in songbirds,we selected candidate genes through annotations from the Mouse Genome Informatics database and assembled an extensive candidate-gene library.Then,w...To search for genes associated with migratory phenotypes in songbirds,we selected candidate genes through annotations from the Mouse Genome Informatics database and assembled an extensive candidate-gene library.Then,we implemented a next-generation sequencing approach to obtain DNA sequences from the Painted Bunting genome.We focused on those sequences that were conserved across avian species and that aligned with candidate genes in our mouse library.We genotyped short sequence repeats from the following candidate genes:ADRA1d,ANKRD17,CISH and MYH7.We studied the possible correlations between allelic variations occurring in these novel candidate migration genes and avian migratory phenotypes available from the published literature.We found that allele variation at MYH7 correlated with a calculated index of speed of migration(km/day)across 11 species of songbirds.We highlight the potential of the Mouse Genome Informatics database in providing new candidate genes that might play a crucial role in regulating migration in birds and possibly in other taxa.Our research effort shows the benefits and limitations of working with extensive genomic datasets and offers a snapshot of the challenges related to cross-species validation in behavioral and molecular ecology studies.展开更多
An insertion fragment in porcine FSHβ subunit gene was cloned by PCR. Sequencing data show that the insertion is a retroposon of 292 bp siting in intronⅠ at the site between +809 and +810 base. Based on these result...An insertion fragment in porcine FSHβ subunit gene was cloned by PCR. Sequencing data show that the insertion is a retroposon of 292 bp siting in intronⅠ at the site between +809 and +810 base. Based on these results, a PCR programme was created to genotype animal individuals in different pig breeds at FSHβ locus and polymorphism of FSHβ gene was analyzed. With the combination of genotype and litter size of sows, it was demonstrated that FSHβ locus is closely associated with major gene controlling litter size in commercial pig breeds, such as Yorkshire, Landrace, Durco. Averagely the AA sows give more 1.5 piglets than BB sows do per litter.展开更多
Osteoporosis, one of the major and growing health problems around the world, is defined asa systemic SKeletal olsease cnaracterized by ,uw bone mass and microarchitectural deterioration of bone tissue, with high bone ...Osteoporosis, one of the major and growing health problems around the world, is defined asa systemic SKeletal olsease cnaracterized by ,uw bone mass and microarchitectural deterioration of bone tissue, with high bone fragility and susceptibility to fractures. In China, 6.97% of the population （ 13 billion ） suffered from osteoporosis in 2000. As far as Hongkong was concerned,展开更多
文摘The traditional roles of a university are teaching and research with the aim of developing society and contributing positively to the national economic development by producing skilled and well-tutored graduates. However, recruitments by these higher institutions are too reliant on the eligibility provided by Resumes of candidates, while neglecting their suitability drawn from their research activity and publications online. This study identifies insights in recruitment trends in higher institutions of learning and uses Artificial Intelligence to produce a more rounded and balanced decision-making process that caters for both eligibility and suitability. The methodology employs the machine learning process using the Multinomial Naïve Bayes for training the model as well as the Vader sentiment analyzer for accuracy and testing. The datasets used contained Resume instances as well as author publication information. The results show a score of 83.9% for the model as well as a sentiment analysis score of 1, indicating an overall positive score. The results show that sentiment analysis can help educational institutions in improving their recruitment models and attracting more suitable candidates for such roles.
基金ICAR-National Rice Research Institute for financial support
文摘Grain size plays a significant role in rice,starting from affecting yield to consumer preference,which is the driving force for deep investigation and improvement of grain size characters.Quantitative inheritance makes these traits complex to breed on account of several alleles contributing to the complete trait expression.We employed genome-wide association study in an association panel of 88 rice genotypes using 142 new candidate gene based SSR(cgSSR)markers,derived from yield-related candidate genes,with the efficient mixed-model association coupled mixed linear model for dissecting complete genetic control of grain size traits.A total of 10 significant associations were identified for four grain size-related characters(grain weight,grain length,grain width,and length-width ratio).Among the identified associations,seven marker trait associations explain more than 10%of the phenotypic variation,indicating major putative QTLs for respective traits.The allelic variations at genes OsBC1L4,SHO1 and OsD2 showed association between 1000-grain weight and grain width,1000-grain weight and grain length,and grain width and length-width ratio,respectively.The cgSSR markers,associated with corresponding traits,can be utilized for direct allelic selection,while other significantly associated cgSSRs may be utilized for allelic accumulation in the breeding programs or grain size improvement.The new cgSSR markers associated with grain size related characters have a significant impact on practical plant breeding to increase the number of causative alleles for these traits through marker aided rice breeding programs.
基金Funding for this research came from the Oklahoma Biological Survey,the National Science Foundation(IDBR#1152356,and DEB#0946685)the United States Department of Agriculture-National Institute of Food and Agriculture(NIFA-AFRI-003536)+1 种基金All work with animals was performed under state and federal banding permits(Permit#23215)was approved by the Institutional Animal Care and Use Committee of the University of Oklahoma(Protocol#R12-019).
文摘To search for genes associated with migratory phenotypes in songbirds,we selected candidate genes through annotations from the Mouse Genome Informatics database and assembled an extensive candidate-gene library.Then,we implemented a next-generation sequencing approach to obtain DNA sequences from the Painted Bunting genome.We focused on those sequences that were conserved across avian species and that aligned with candidate genes in our mouse library.We genotyped short sequence repeats from the following candidate genes:ADRA1d,ANKRD17,CISH and MYH7.We studied the possible correlations between allelic variations occurring in these novel candidate migration genes and avian migratory phenotypes available from the published literature.We found that allele variation at MYH7 correlated with a calculated index of speed of migration(km/day)across 11 species of songbirds.We highlight the potential of the Mouse Genome Informatics database in providing new candidate genes that might play a crucial role in regulating migration in birds and possibly in other taxa.Our research effort shows the benefits and limitations of working with extensive genomic datasets and offers a snapshot of the challenges related to cross-species validation in behavioral and molecular ecology studies.
文摘An insertion fragment in porcine FSHβ subunit gene was cloned by PCR. Sequencing data show that the insertion is a retroposon of 292 bp siting in intronⅠ at the site between +809 and +810 base. Based on these results, a PCR programme was created to genotype animal individuals in different pig breeds at FSHβ locus and polymorphism of FSHβ gene was analyzed. With the combination of genotype and litter size of sows, it was demonstrated that FSHβ locus is closely associated with major gene controlling litter size in commercial pig breeds, such as Yorkshire, Landrace, Durco. Averagely the AA sows give more 1.5 piglets than BB sows do per litter.
基金The study was partially supported by a key project grant fromNational Science Foundation of China (No.30230210)
文摘Osteoporosis, one of the major and growing health problems around the world, is defined asa systemic SKeletal olsease cnaracterized by ,uw bone mass and microarchitectural deterioration of bone tissue, with high bone fragility and susceptibility to fractures. In China, 6.97% of the population （ 13 billion ） suffered from osteoporosis in 2000. As far as Hongkong was concerned,
