We have previously reported that Cystatin C(CysC) is a pivotal mediator in the neuroprotection induced by hyperbaric oxygen(HBO) preconditioning; however,the underlying mechanism and how CysC changes after stroke are ...We have previously reported that Cystatin C(CysC) is a pivotal mediator in the neuroprotection induced by hyperbaric oxygen(HBO) preconditioning; however,the underlying mechanism and how CysC changes after stroke are not clear. In the present study, we demonstrated that CysC expression was elevated as early as 3 h after reperfusion, and this was further enhanced by HBO preconditioning. Concurrently, LC3-II and Beclin-1, two positive-markers for autophagy induction, exhibited increases similar to CysC, while knockdown of CysC blocked these elevations. As a marker of autophagy inhibition, p62 was downregulated by HBO preconditioning and this was blocked by CysC knockdown. Besides, the beneficial effects of preserving lysosomal membrane integrity and enhancing autolysosome formation induced by HBO preconditioning were abolished in CysC-/-rats.Furthermore, we demonstrated that exogenous CysC reduced the neurological deficits and infarct volume after brain ischemic injury, while 3-methyladenine partially reversed this neuroprotection. In the present study, we showed that CysC is biochemically and morphologically essential for promoting autophagic flux, and highlighted the translational potential of HBO preconditioning and CysC for stroke treatment.展开更多
Aims Vegetation type is important in determining variations in soil carbon(C)efflux under grassland managements.This study was conducted to examine the effects of mowing and nitrogen(N)addition on soil respiration and...Aims Vegetation type is important in determining variations in soil carbon(C)efflux under grassland managements.This study was conducted to examine the effects of mowing and nitrogen(N)addition on soil respiration and their dependences upon vegetation types in an oldfield grassland of northern China.Methods Soil respiration,temperature,moisture and aboveground net primary productivity(ANPP)and belowground net primary productivity(BNPP)were examined in response to mowing and N addition among the three patches dominated by different species(named as grass,forb and mixed patches,respectively)in the growing seasons(May–October)from 2006 to 2008.Important Findings Across the 3 years,soil respiration in the grass patch was greater than those in the forb and mixed patches,which could have been ascribed to the higher soil moisture(SM)in the grass patch.Mowing had no impact on soil respiration due to unaltered SM and plant growth.Soil respiration was stimulated by 6.53%under N addition,and the enhancement was statistically significant in 2006 but not in 2007 or 2008 because of the limited water availability in the later 2 years.There were no interactive effects between mowing and N addition on soil respiration.Soil respiration showed positive dependence upon SM,ANPP and BNPP across plots.The results suggest that soil water availability and plant growth could be the primary factors in controlling the temporal and spatial variations in soil respiration and its response to different treatments.Our observations indicate that grassland managements(i.e.mowing for hay once a year)may have little influence on soil respiration of the oldfield grassland in northern China.展开更多
The China Seas include the South China Sea, East China Sea, Yellow Sea, and Bohai Sea. Located off the Northwestern Pacific margin, covering 4700000 km^2 from tropical to northern temperate zones, and including a vari...The China Seas include the South China Sea, East China Sea, Yellow Sea, and Bohai Sea. Located off the Northwestern Pacific margin, covering 4700000 km^2 from tropical to northern temperate zones, and including a variety of continental margins/basins and depths, the China Seas provide typical cases for carbon budget studies. The South China Sea being a deep basin and part of the Western Pacific Warm Pool is characterized by oceanic features; the East China Sea with a wide continental shelf, enormous terrestrial discharges and open margins to the West Pacific, is featured by strong cross-shelf materials transport; the Yellow Sea is featured by the confluence of cold and warm waters; and the Bohai Sea is a shallow semiclosed gulf with strong impacts of human activities. Three large rivers, the Yangtze River, Yellow River, and Pearl River, flow into the East China Sea, the Bohai Sea, and the South China Sea, respectively. The Kuroshio Current at the outer margin of the Chinese continental shelf is one of the two major western boundary currents of the world oceans and its strength and position directly affect the regional climate of China. These characteristics make the China Seas a typical case of marginal seas to study carbon storage and fluxes. This paper systematically analyzes the literature data on the carbon pools and fluxes of the Bohai Sea,Yellow Sea, East China Sea, and South China Sea, including different interfaces(land-sea, sea-air, sediment-water, and marginal sea-open ocean) and different ecosystems(mangroves, wetland, seagrass beds, macroalgae mariculture, coral reefs, euphotic zones, and water column). Among the four seas, the Bohai Sea and South China Sea are acting as CO_2 sources, releasing about0.22 and 13.86–33.60 Tg C yr^(-1) into the atmosphere, respectively, whereas the Yellow Sea and East China Sea are acting as carbon sinks, absorbing about 1.15 and 6.92–23.30 Tg C yr^(-1) of atmospheric CO_2, respectively. Overall, if only the CO_2 exchange at the sea-air interface is considered, the C展开更多
Transport of organic carbon via rivers to estuary is a significant geochemical proc- ess in the global carbon cycle. This paper presents bulk total organic carbon （TOC） from the Dongjiang catchment to the adjacent H...Transport of organic carbon via rivers to estuary is a significant geochemical proc- ess in the global carbon cycle. This paper presents bulk total organic carbon （TOC） from the Dongjiang catchment to the adjacent Humen outlet, and discusses the applicability of 613C and ratio of carbon to nitrogen （C/N） as indicators for sources of organic matter in the surface sediments. Survey results showed that organic carbon concentration in summer were higher than in the winter. An elevated trend of TOC occurred along the river to the Humen outlet in both surveys, and the highest mean values of dissolved and particular organic carbon （DOC-279 μmol L-1 and POC-163μmol L-1） were observed in the urban deltaic region in summer flood flow. Winter samples had a wide range of b＇13C and C/N （5-3C -24.6%o to -30.0%o, C/N 4-13）, and summer ones varied slightly （8-3C -24.2%o to -27.6%0, C/N 6-18）. As results suggest that POC in the three zones of upstream-delta-outlet dominantly came from riverbank soil, phytoplankton and agricultural C3 plants in winter, whereas main sources were from the riverbank and mangrove soil in summer. Moreover, anthropogenic sewage inputs had 11% and 7% contribution to POC in the deltaic and outlet. Transport accompanied with seasonal freshwater variation, phytoplankton production and degradation, and removal be- havior caused variation of organic carbon concentration. The results also discovered that TOC export bulk in Dongjiang was approximately one quarter of Humen flux in the dry flow, and anthropogenic activity significantly impacted the river export contribution.展开更多
We carried out a downscaling treatment over China using the CarbonTracker numerical model,which was applied using double grid nesting technology(3°×2°over the whole globe,1°×1°over China)...We carried out a downscaling treatment over China using the CarbonTracker numerical model,which was applied using double grid nesting technology(3°×2°over the whole globe,1°×1°over China),simulating and analyzing atmospheric CO2concentrations over 10 recent years(2000–2009).The simulation results agreed very well with observed data from four background atmospheric monitoring stations in China(The periods for which the simulation results and observed values be compared were January2000 to December 2009 for the WLG station and June 2006 to December 2009 for the SDZ,LFS,and LAN stations),giving correlation coefficients of>0.7.The high-resolution simulation data correlated slightly better than the low resolution simulation data with the observed data for three of the regions’atmospheric background stations.Further analysis of the annual,seasonal CO2concentration variations at the background stations showed that the CO2concentration increased each year over the study period,with an average annual increase of more than 5%,and annual increases of more than 7%at the Shangdianzi and Lin’an stations.Seasonal CO2variations were greater at the Longfengshan station than at the Shangdianzi or Lin’an stations.However,the CO2concentrations were higher at the Shangdianzi and Lin’an stations because they are greatly affected by human activities in the Jingjinji and Changjiang Delta economic zones.Spatial distribution in CO2concentrations and fluxes were higher in eastern than in western China.展开更多
Using the data taken from Tibet II High Density （HD） Array （1997 February-1999 September） and Tibet-III array （1999 November--2005 November）, our previous northern sky survey for TeV γ-ray point sources has now...Using the data taken from Tibet II High Density （HD） Array （1997 February-1999 September） and Tibet-III array （1999 November--2005 November）, our previous northern sky survey for TeV γ-ray point sources has now been updated by a factor of 2.8 improved statistics. From 0.0° to 60.0° in declination （Dec） range, no new TeV T-ray point sources with sufficiently high significance were identified while the well-known Crab Nebula and Mrk421 remain to be the brightest TeV γ-ray sources within the field of view of the Tibet air shower array. Based on the currently available data and at the 90% confidence level （C.L.）, the flux upper limits for different power law index assumption are re-derived, which are approximately improved by 1.7 times as compared with our previous reported limits.展开更多
应用微气象法中的梯度观测系统、涡度相关系统和闭路水汽-CO2廓线系统,使用设置在海南省西部儋州地区一片刚开割的橡胶林中观测铁塔上的观测仪器所得的干季7个晴好天气的微气候观测数据和通量观测数据,对其微气候特征和通量特征进行初...应用微气象法中的梯度观测系统、涡度相关系统和闭路水汽-CO2廓线系统,使用设置在海南省西部儋州地区一片刚开割的橡胶林中观测铁塔上的观测仪器所得的干季7个晴好天气的微气候观测数据和通量观测数据,对其微气候特征和通量特征进行初步分析研究。结果表明:(1)橡胶林的辐射通量与光合有效辐射(photosynthetically active radiation,PAR)呈明显的昼夜交替变化;橡胶林林内和林冠上风速昼夜变化明显,风向则多为东北风(15°～40°);林冠上方气温和树冠面表温具有显著的日变化特征,树冠表温日变化幅度大于气温;相同时刻干季橡胶林林冠上方和林冠内湿度和水汽压相差不大;林冠内CO2浓度夜高昼低;土壤温度日变化明显,土壤含水量变幅较小。(2)林冠上方显热通量与潜热通量变化趋势相同,显热通量小于潜热通量;净辐射通量日变化呈规则的倒"U"形,主要由下行短波辐射决定;土壤热通量存在日变化,随土层深度增加变化变小;CO2通量随光合有效辐射发生日变化;水汽通量随净辐射发生日变化。展开更多
基金supported by the National Natural Science Foundation of China(81420108013,81730032)a Young Scholar Research Grant from the Chinese Anesthesiologist Association(21700005)Youth Project(81300989)
文摘We have previously reported that Cystatin C(CysC) is a pivotal mediator in the neuroprotection induced by hyperbaric oxygen(HBO) preconditioning; however,the underlying mechanism and how CysC changes after stroke are not clear. In the present study, we demonstrated that CysC expression was elevated as early as 3 h after reperfusion, and this was further enhanced by HBO preconditioning. Concurrently, LC3-II and Beclin-1, two positive-markers for autophagy induction, exhibited increases similar to CysC, while knockdown of CysC blocked these elevations. As a marker of autophagy inhibition, p62 was downregulated by HBO preconditioning and this was blocked by CysC knockdown. Besides, the beneficial effects of preserving lysosomal membrane integrity and enhancing autolysosome formation induced by HBO preconditioning were abolished in CysC-/-rats.Furthermore, we demonstrated that exogenous CysC reduced the neurological deficits and infarct volume after brain ischemic injury, while 3-methyladenine partially reversed this neuroprotection. In the present study, we showed that CysC is biochemically and morphologically essential for promoting autophagic flux, and highlighted the translational potential of HBO preconditioning and CysC for stroke treatment.
基金National Basic Research Program(2007CB106803)National Natural Science Foundation of China(30925009).
文摘Aims Vegetation type is important in determining variations in soil carbon(C)efflux under grassland managements.This study was conducted to examine the effects of mowing and nitrogen(N)addition on soil respiration and their dependences upon vegetation types in an oldfield grassland of northern China.Methods Soil respiration,temperature,moisture and aboveground net primary productivity(ANPP)and belowground net primary productivity(BNPP)were examined in response to mowing and N addition among the three patches dominated by different species(named as grass,forb and mixed patches,respectively)in the growing seasons(May–October)from 2006 to 2008.Important Findings Across the 3 years,soil respiration in the grass patch was greater than those in the forb and mixed patches,which could have been ascribed to the higher soil moisture(SM)in the grass patch.Mowing had no impact on soil respiration due to unaltered SM and plant growth.Soil respiration was stimulated by 6.53%under N addition,and the enhancement was statistically significant in 2006 but not in 2007 or 2008 because of the limited water availability in the later 2 years.There were no interactive effects between mowing and N addition on soil respiration.Soil respiration showed positive dependence upon SM,ANPP and BNPP across plots.The results suggest that soil water availability and plant growth could be the primary factors in controlling the temporal and spatial variations in soil respiration and its response to different treatments.Our observations indicate that grassland managements(i.e.mowing for hay once a year)may have little influence on soil respiration of the oldfield grassland in northern China.
基金supported by the National Key Research and Development Program of China (Grant No. 2016YFA0601400)the National Natural Science Foundation of China (Grant Nos. 91751207, 91428308, 41722603, 41606153 and 41422603)+1 种基金the Fundamental Research Funds for the Central Universities (Grant No. 20720170107)CNOOC Projects (Grant Nos. CNOOC-KJ125FZDXM00TJ001-2014 and CNOOCKJ125FZDXM00ZJ001-2014)
文摘The China Seas include the South China Sea, East China Sea, Yellow Sea, and Bohai Sea. Located off the Northwestern Pacific margin, covering 4700000 km^2 from tropical to northern temperate zones, and including a variety of continental margins/basins and depths, the China Seas provide typical cases for carbon budget studies. The South China Sea being a deep basin and part of the Western Pacific Warm Pool is characterized by oceanic features; the East China Sea with a wide continental shelf, enormous terrestrial discharges and open margins to the West Pacific, is featured by strong cross-shelf materials transport; the Yellow Sea is featured by the confluence of cold and warm waters; and the Bohai Sea is a shallow semiclosed gulf with strong impacts of human activities. Three large rivers, the Yangtze River, Yellow River, and Pearl River, flow into the East China Sea, the Bohai Sea, and the South China Sea, respectively. The Kuroshio Current at the outer margin of the Chinese continental shelf is one of the two major western boundary currents of the world oceans and its strength and position directly affect the regional climate of China. These characteristics make the China Seas a typical case of marginal seas to study carbon storage and fluxes. This paper systematically analyzes the literature data on the carbon pools and fluxes of the Bohai Sea,Yellow Sea, East China Sea, and South China Sea, including different interfaces(land-sea, sea-air, sediment-water, and marginal sea-open ocean) and different ecosystems(mangroves, wetland, seagrass beds, macroalgae mariculture, coral reefs, euphotic zones, and water column). Among the four seas, the Bohai Sea and South China Sea are acting as CO_2 sources, releasing about0.22 and 13.86–33.60 Tg C yr^(-1) into the atmosphere, respectively, whereas the Yellow Sea and East China Sea are acting as carbon sinks, absorbing about 1.15 and 6.92–23.30 Tg C yr^(-1) of atmospheric CO_2, respectively. Overall, if only the CO_2 exchange at the sea-air interface is considered, the C
基金National Natural Science Foundation of China, No.41101152 No.40901090+5 种基金 No.41172315 The Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry The talents in- troduced into Universities Foundation of Guangdong Province of China The China Scholarship Council （CSC） funding in 2013 The Universities Disciplinary and Special Construction Funds of Guangdong Prov- ince Foundation, No.C 10092 The Scientific Research Foundation of Graduate School of South China Nor- mal University
文摘Transport of organic carbon via rivers to estuary is a significant geochemical proc- ess in the global carbon cycle. This paper presents bulk total organic carbon （TOC） from the Dongjiang catchment to the adjacent Humen outlet, and discusses the applicability of 613C and ratio of carbon to nitrogen （C/N） as indicators for sources of organic matter in the surface sediments. Survey results showed that organic carbon concentration in summer were higher than in the winter. An elevated trend of TOC occurred along the river to the Humen outlet in both surveys, and the highest mean values of dissolved and particular organic carbon （DOC-279 μmol L-1 and POC-163μmol L-1） were observed in the urban deltaic region in summer flood flow. Winter samples had a wide range of b＇13C and C/N （5-3C -24.6%o to -30.0%o, C/N 4-13）, and summer ones varied slightly （8-3C -24.2%o to -27.6%0, C/N 6-18）. As results suggest that POC in the three zones of upstream-delta-outlet dominantly came from riverbank soil, phytoplankton and agricultural C3 plants in winter, whereas main sources were from the riverbank and mangrove soil in summer. Moreover, anthropogenic sewage inputs had 11% and 7% contribution to POC in the deltaic and outlet. Transport accompanied with seasonal freshwater variation, phytoplankton production and degradation, and removal be- havior caused variation of organic carbon concentration. The results also discovered that TOC export bulk in Dongjiang was approximately one quarter of Humen flux in the dry flow, and anthropogenic activity significantly impacted the river export contribution.
基金supported by the National Basic Research Program of China (2010CB950601)the International S & T Cooperation Program MOST (2011DFA21090)the National Natural Science Foundation of China (41175116)
文摘We carried out a downscaling treatment over China using the CarbonTracker numerical model,which was applied using double grid nesting technology(3°×2°over the whole globe,1°×1°over China),simulating and analyzing atmospheric CO2concentrations over 10 recent years(2000–2009).The simulation results agreed very well with observed data from four background atmospheric monitoring stations in China(The periods for which the simulation results and observed values be compared were January2000 to December 2009 for the WLG station and June 2006 to December 2009 for the SDZ,LFS,and LAN stations),giving correlation coefficients of>0.7.The high-resolution simulation data correlated slightly better than the low resolution simulation data with the observed data for three of the regions’atmospheric background stations.Further analysis of the annual,seasonal CO2concentration variations at the background stations showed that the CO2concentration increased each year over the study period,with an average annual increase of more than 5%,and annual increases of more than 7%at the Shangdianzi and Lin’an stations.Seasonal CO2variations were greater at the Longfengshan station than at the Shangdianzi or Lin’an stations.However,the CO2concentrations were higher at the Shangdianzi and Lin’an stations because they are greatly affected by human activities in the Jingjinji and Changjiang Delta economic zones.Spatial distribution in CO2concentrations and fluxes were higher in eastern than in western China.
基金Supported by Grants-in-Aid for Scientific Research on Priority Areas (712) (MEXT)Japan Society for Promotion of Science(JSPS)+1 种基金National Natural Science Foundation of China (10675134,10533020)Chinese Academy of Sciences
文摘Using the data taken from Tibet II High Density （HD） Array （1997 February-1999 September） and Tibet-III array （1999 November--2005 November）, our previous northern sky survey for TeV γ-ray point sources has now been updated by a factor of 2.8 improved statistics. From 0.0° to 60.0° in declination （Dec） range, no new TeV T-ray point sources with sufficiently high significance were identified while the well-known Crab Nebula and Mrk421 remain to be the brightest TeV γ-ray sources within the field of view of the Tibet air shower array. Based on the currently available data and at the 90% confidence level （C.L.）, the flux upper limits for different power law index assumption are re-derived, which are approximately improved by 1.7 times as compared with our previous reported limits.
文摘应用微气象法中的梯度观测系统、涡度相关系统和闭路水汽-CO2廓线系统,使用设置在海南省西部儋州地区一片刚开割的橡胶林中观测铁塔上的观测仪器所得的干季7个晴好天气的微气候观测数据和通量观测数据,对其微气候特征和通量特征进行初步分析研究。结果表明:(1)橡胶林的辐射通量与光合有效辐射(photosynthetically active radiation,PAR)呈明显的昼夜交替变化;橡胶林林内和林冠上风速昼夜变化明显,风向则多为东北风(15°～40°);林冠上方气温和树冠面表温具有显著的日变化特征,树冠表温日变化幅度大于气温;相同时刻干季橡胶林林冠上方和林冠内湿度和水汽压相差不大;林冠内CO2浓度夜高昼低;土壤温度日变化明显,土壤含水量变幅较小。(2)林冠上方显热通量与潜热通量变化趋势相同,显热通量小于潜热通量;净辐射通量日变化呈规则的倒"U"形,主要由下行短波辐射决定;土壤热通量存在日变化,随土层深度增加变化变小;CO2通量随光合有效辐射发生日变化;水汽通量随净辐射发生日变化。
