摘要
目的 探讨非穿透性小梁手术联合T-Flux植入治疗青少年型青光眼的临床疗效。方法 对15例(19只眼)青少年型青光眼患者，行非穿透性小梁手术(nonpenetrating trabecular surgery，NPTS)联合丝裂霉素C(MMC)并植入T-Flux术，术后观察滤过泡、前房、眼内反应、眼压、视力、眼底及并发症。随访时间3周～30月，平均(8．9±7．7)月。结果 患者术前眼压21～50mmHg，平均(37．7±9．5)mmHg，术后1周平均眼压(9．6±3．4)mmHg(19只眼)，术后1月平均眼压(15．5±3．3)mmHg(15只眼)，术后6月平均眼压(14．0±3．0)mmHg(10只眼)，术后10月平均眼压(15．0±2．9)mmHg(7只眼)，术后1年平均眼压(14．8±3．8)mmHg(5只眼)，术后2年平均眼压(18．0±2．0)mmHg(3只眼)，术后2年半平均眼压(19．0±0)mmHg(1只眼)，与术前相比差异有非常显著性(P<0．01)。复发需再手术1只眼，其余眼压均在21mmHg以下，成功率94．4％。视力与视乳头杯盘比(C／D)手术前后无明显变化。术后并发症主要有前房出血2只眼(10．52％)、I度浅前房2只眼(10．52％)，未见滤过泡漏及睫状体脉络膜脱离，术中发生部分穿透5只眼(26．31％)。结论NPTS+MMC+T-Flux术是安全有效的治疗青少年型青光眼的理想方法。
Objectiye To evaluate the efficacy of nonpenetrating trabecular surgery With. T-Flux Implantation for treating juvenile glaucoma . Methods Fifteen eases （19 eyes） of juvenile glaucoma underwent nonpenetrating trabeeular surgery （NPTS） using Mitomyein C （MMC） with implantation of T-Flux. The postoperative filtering bleb,anterior ehamber,intraoeular reaetions,intraoeular pressure （IOP）, visual acuity,Ocular Fundus and complication were recorded. The follow-up was 3 weeks to 30 months, meanly （8. 94±7.7） month. Results The preoperative IOP was 21-50mmHg,meanly （37.7±9.5）mmHg. The mean IOP was（9.6±3.4）mmHg in 19 eyes 1 week after operation, was （15.5 ± 3.3）mmHg in 15 eyes 1 month after operation, was （14.0 ± 3. 0）mmHg in 10 eyes 6 months after operation ,was （15.0 ± 2.9）mmHg in7 eyes 10 months after operation, was （14.8 ± 3.8）mmHg in 5 eyes 1 year after operation,was（18.0±2.0）mmHg in 3 eyes 2 years after operation, was（19±0）mmHg in 1 eye 30 months after operation, it is significant （P〈0.01）comparing with preoperative figures. Except 1 eye recrudesced and need another operation, the IOP of other eyes was below 21mmHg,the successful rate was 94.4%. There is no significant difference between the preoperative and postoperative visual acuity and optic papilla cup-toisc ratio（C/D）. The main postoperative complications were hyphema （2 eyes account for 10. 52 %）, shallow anterior chamber （2 eyes account for 10. 52 %）, no filtering bleb leak and detachment of choroid were observed,partial penetrating occurred in 5 eyes during operation. Conclusion NPTS＋ MMC＋ T-Flux operative method is safe and effective. It is an ideal method for treating juvenile glaucoma.
出处
《临床眼科杂志》
2005年第4期324-326,共3页
Journal of Clinical Ophthalmology
