<b><span style="font-family:Verdana;">The objective of our study</span></b><span style="font-family:;" "=""><span style="font-family:Verdana;&qu...<b><span style="font-family:Verdana;">The objective of our study</span></b><span style="font-family:;" "=""><span style="font-family:Verdana;"> was to investigate the association between the Arg16Gly polymorphism in the </span><i><span style="font-family:Verdana;">β</span></i><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">-АR gene and body mass index (BMI) in patients with bronchial asthma (BA) with regard to the age of onset. </span><b><span style="font-family:Verdana;">Materials and methods</span></b></span><b><span style="font-family:Verdana;">:</span></b><span style="font-family:;" "=""><span style="font-family:Verdana;"> 553 patients were examined. The control group consisted of 95 apparently healthy individuals. The patients were divided into 2 groups depending on the age of BA onset: 282 patients with late onset (Group I) and 271 patients with early onset (Group II). Arg16Gly polymorphism in the </span><i><span style="font-family:Verdana;">β</span></i><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">-АR gene (rs1042713) was determined using polymerase chain reaction-</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">restriction fragment length polymorphism analysis. Statistical analysis of obtained results was performed using SPSS–17 program. </span><b><span style="font-family:Verdana;">Results</span></b></span><b><span style="font-family:Verdana;">:</span><span style="font-family:;" "=""> </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">There was no significant difference in the distribution of genotypes for Arg16Gly polymorphism in the </span><i><span style="font-family:Verdana;">β</span></i><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">-AR gene depending on BMI (</span><i><span style="font-family:Verdana;">χ</span></i><sup><span style="font-family:Verdana;">2</span></sup><展开更多
文摘<b><span style="font-family:Verdana;">The objective of our study</span></b><span style="font-family:;" "=""><span style="font-family:Verdana;"> was to investigate the association between the Arg16Gly polymorphism in the </span><i><span style="font-family:Verdana;">β</span></i><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">-АR gene and body mass index (BMI) in patients with bronchial asthma (BA) with regard to the age of onset. </span><b><span style="font-family:Verdana;">Materials and methods</span></b></span><b><span style="font-family:Verdana;">:</span></b><span style="font-family:;" "=""><span style="font-family:Verdana;"> 553 patients were examined. The control group consisted of 95 apparently healthy individuals. The patients were divided into 2 groups depending on the age of BA onset: 282 patients with late onset (Group I) and 271 patients with early onset (Group II). Arg16Gly polymorphism in the </span><i><span style="font-family:Verdana;">β</span></i><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">-АR gene (rs1042713) was determined using polymerase chain reaction-</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">restriction fragment length polymorphism analysis. Statistical analysis of obtained results was performed using SPSS–17 program. </span><b><span style="font-family:Verdana;">Results</span></b></span><b><span style="font-family:Verdana;">:</span><span style="font-family:;" "=""> </span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">There was no significant difference in the distribution of genotypes for Arg16Gly polymorphism in the </span><i><span style="font-family:Verdana;">β</span></i><sub><span style="font-family:Verdana;">2</span></sub><span style="font-family:Verdana;">-AR gene depending on BMI (</span><i><span style="font-family:Verdana;">χ</span></i><sup><span style="font-family:Verdana;">2</span></sup><
