Aim: This study was aimed to review and establish the practice of exchange transfusion (ET) with whole blood reconstituted (WBR) in hemolytic disease of newborn (HDN). Objectives: To observe fall in indirect serum bil...Aim: This study was aimed to review and establish the practice of exchange transfusion (ET) with whole blood reconstituted (WBR) in hemolytic disease of newborn (HDN). Objectives: To observe fall in indirect serum bilirubin, correction of anemia and comparison with related studies. Background: Hemolytic disease of the Newborn is characterized by presence of IgG antibodies in maternal circulation, which causes hemolysis in the fetus by crossing the placenta and sensitizing red cells for destruction by macrophages in the fetal spleen with consequent hyperbilirubinemia. Exchange transfusion with or without phototherapy is the method of choice for treating the newborn with on going hemolysis Methods/Materials: Sample size consisted of 110 neonates in whom 119 exchange transfusions were carried out with WBR. WBR was prepared by suspending O Rhesus-D (RhD) positive/negative cells (compatible with neonate’s/ mother’s serum) in AB plasma. Double volume exchange transfusion(s) were carried out through umbilical vein by push-pull technique. Results: Out of 110 cases, 61 (55.5%) were of RhD HDN whereas ABO and other group HDN cases were 30 (27.3%) and 19 (17.3%) respectively. An average post-ET fall in indirect serum bilirubin by 54.6% and correction of anemia by3.7 gm/dl were reported in the study. Conclusion: An average post-ET fall in indirect serum bilirubin and correction of anemia was found to be more significant when compared to other studies. Hence we recommend exchange transfusion in HDN with WBR to obtain reasonable fall in indirect serum bilirubin and high average rate of correction of anemia.展开更多
为了维护电网安全稳定运行,加强对山火的预防,通过考虑主备路由的链路重要度评估算法(Link Importance Evaluation Algorithm Based on Working and Backup Routing,WBR-LIEA)对电网输电线路中山火预警监测系统进行了优化。首先对山火...为了维护电网安全稳定运行,加强对山火的预防,通过考虑主备路由的链路重要度评估算法(Link Importance Evaluation Algorithm Based on Working and Backup Routing,WBR-LIEA)对电网输电线路中山火预警监测系统进行了优化。首先对山火预警监测系统进行了分析,然后利用WBR-LIEA算法对山火预警系统从服务层、传输层和物理拓扑层进行了关联风险值的评估,再将三个层面的链路关联风险进行融合,用来度量网络中链路的重要度。当链路失效引起路由中断时,控制器将按照重要度对路由进行重新分配,避免山火对报警通信系统产生影响,导致预警不及时。最后在电力通信网上对算法进行仿真实验并进行了相关分析,证明了该算法的准确性和有效性。展开更多
文摘Aim: This study was aimed to review and establish the practice of exchange transfusion (ET) with whole blood reconstituted (WBR) in hemolytic disease of newborn (HDN). Objectives: To observe fall in indirect serum bilirubin, correction of anemia and comparison with related studies. Background: Hemolytic disease of the Newborn is characterized by presence of IgG antibodies in maternal circulation, which causes hemolysis in the fetus by crossing the placenta and sensitizing red cells for destruction by macrophages in the fetal spleen with consequent hyperbilirubinemia. Exchange transfusion with or without phototherapy is the method of choice for treating the newborn with on going hemolysis Methods/Materials: Sample size consisted of 110 neonates in whom 119 exchange transfusions were carried out with WBR. WBR was prepared by suspending O Rhesus-D (RhD) positive/negative cells (compatible with neonate’s/ mother’s serum) in AB plasma. Double volume exchange transfusion(s) were carried out through umbilical vein by push-pull technique. Results: Out of 110 cases, 61 (55.5%) were of RhD HDN whereas ABO and other group HDN cases were 30 (27.3%) and 19 (17.3%) respectively. An average post-ET fall in indirect serum bilirubin by 54.6% and correction of anemia by3.7 gm/dl were reported in the study. Conclusion: An average post-ET fall in indirect serum bilirubin and correction of anemia was found to be more significant when compared to other studies. Hence we recommend exchange transfusion in HDN with WBR to obtain reasonable fall in indirect serum bilirubin and high average rate of correction of anemia.
文摘为了维护电网安全稳定运行,加强对山火的预防,通过考虑主备路由的链路重要度评估算法(Link Importance Evaluation Algorithm Based on Working and Backup Routing,WBR-LIEA)对电网输电线路中山火预警监测系统进行了优化。首先对山火预警监测系统进行了分析,然后利用WBR-LIEA算法对山火预警系统从服务层、传输层和物理拓扑层进行了关联风险值的评估,再将三个层面的链路关联风险进行融合,用来度量网络中链路的重要度。当链路失效引起路由中断时,控制器将按照重要度对路由进行重新分配,避免山火对报警通信系统产生影响,导致预警不及时。最后在电力通信网上对算法进行仿真实验并进行了相关分析,证明了该算法的准确性和有效性。
