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Review of Key Problems Related to Integrated Energy Distribution Systems 被引量:57
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作者 Dan Wang Liu Liu +4 位作者 Hongjie Jia Weiliang Wang yunqiang Zhi Zhengji Meng Bingyu Zhou 《CSEE Journal of Power and Energy Systems》 SCIE 2018年第2期130-145,共16页
Integrated energy distribution system(IEDS)is one of the integrated energy and power system forms,which involves electricity/gas/cold/heat and other various energy forms.The energy coupling relationship is close and c... Integrated energy distribution system(IEDS)is one of the integrated energy and power system forms,which involves electricity/gas/cold/heat and other various energy forms.The energy coupling relationship is close and complex.IEDS is the focus of regional energy internet research and development at home and abroad.Compared with the traditional power distribution system,IEDS through the multi-energy coupling link comprehensive utilization,effectively improve the distribution system economy,safety,reliability,flexibility and toughness,but also to ease the regional energy system environmental pressure.IEDS is an important direction for the future development of energy systems,and its related research and practice on China’s energy system development also has important practical and strategic significance.This paper summarizes the related researches of the IEDS and explores the energy operation characteristics and coupling mechanisms.What’s more,the integrated model of IEDS is summarized.On these bases,this paper discusses and prospects some key issues such as joint planning,optimization control and security analysis,state estimation and situational awareness and generalized demand side management. 展开更多
关键词 Energy internet generalized demand side management integrated energy distribution system(IEDS) integrated modeling joint planning optimization control and security analysis state estimation and situational awareness
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中国心血管影像技术应用现状调查与医疗质量报告 被引量:34
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作者 吕滨 任心爽 +6 位作者 安云强 赵迎新 李希 李静 卢光明 金征宇 《中国循环杂志》 CSCD 北大核心 2020年第7期625-633,共9页
无创心血管影像技术的应用,正逐渐成为稳定性冠心病诊断的主力军。然而,目前在我国缺乏诊断冠心病影像学技术应用情况的调研数据。“心血管影像质控专家工作组”于2018年开始,对全国二级以上医院进行随机抽样横断面调查,结果显示经导管... 无创心血管影像技术的应用,正逐渐成为稳定性冠心病诊断的主力军。然而,目前在我国缺乏诊断冠心病影像学技术应用情况的调研数据。“心血管影像质控专家工作组”于2018年开始,对全国二级以上医院进行随机抽样横断面调查,结果显示经导管冠状动脉造影的开展率为65.8%,冠状动脉CT血管成像(CTA)的开展率为64.5%,而负荷超声心动图(9.0%)、心脏磁共振成像(13.5%)及核素心肌灌注显像(12.9%)等检查技术均未得到广泛开展。本研究通过收集冠状动脉CTA操作规程及原始图像,对图像质量进行评估,结果显示三级医院冠状动脉CTA图像质量优良率为90.8%,二级医院为87.3%,检查失败率分别为3.7%和8.5%。无论三级医院(平均11.5 mSv)还是二级医院(平均12.7 mSv),给予患者的辐射剂量均过高。本次调查还包括放射影像工作人员现状,以及其它常见心血管病的影像检查现状。通过本次调查,得到以下初步结论:冠状动脉CTA检查成为我国冠心病早期诊断和筛查的主要技术工具,其普及使用率与经导管冠状动脉造影接近,而负荷超声心动图、心脏磁共振成像和核素心肌灌注显像技术的应用明显不足。冠状动脉CTA图像质量基本能够满足临床诊断要求,但是有进一步提高图像质量的空间,特别是低辐射剂量的规范化扫描技术亟待普及提高。 展开更多
关键词 心血管影像 横断面调查 应用现状 质量控制
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COVID-19: Challenges to GIS with Big Data 被引量:31
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作者 Chenghu Zhou Fenzhen Su +18 位作者 Tao Pei An Zhang Yunyan Du Bin Luo Zhidong Cao Juanle Wang Wen Yuan yunqiang Zhu Ci Song Jie Chen Jun Xu Fujia Li Ting Ma Lili Jiang Fengqin Yan Jiawei Yi Yunfeng Hu Yilan Liao Han Xiao 《Geography and Sustainability》 2020年第1期77-87,共11页
The outbreak of the 2019 novel coronavirus disease(COVID-19)has caused more than 100,000 people infected and thousands of deaths.Currently,the number of infections and deaths is still increasing rapidly.COVID-19 serio... The outbreak of the 2019 novel coronavirus disease(COVID-19)has caused more than 100,000 people infected and thousands of deaths.Currently,the number of infections and deaths is still increasing rapidly.COVID-19 seriously threatens human health,production,life,social functioning and international relations.In the fight against COVID-19,Geographic Information Systems(GIS)and big data technologies have played an important role in many aspects,including the rapid aggregation of multi-source big data,rapid visualization of epidemic information,spatial tracking of confirmed cases,prediction of regional transmission,spatial segmentation of the epidemic risk and prevention level,balancing and management of the supply and demand of material resources,and socialemotional guidance and panic elimination,which provided solid spatial information support for decision-making,measures formulation,and effectiveness assessment of COVID-19 prevention and control.GIS has developed and matured relatively quickly and has a complete technological route for data preparation,platform construction,model construction,and map production.However,for the struggle against the widespread epidemic,the main challenge is finding strategies to adjust traditional technical methods and improve speed and accuracy of information provision for social management.At the data level,in the era of big data,data no longer come mainly from the government but are gathered from more diverse enterprises.As a result,the use of GIS faces difficulties in data acquisition and the integration of heterogeneous data,which requires governments,businesses,and academic institutions to jointly promote the formulation of relevant policies.At the technical level,spatial analysis methods for big data are in the ascendancy.Currently and for a long time in the future,the development of GIS should be strengthened to form a data-driven system for rapid knowledge acquisition,which signifies ts that GIS should be used to reinforce the social operation parameterization of models and 展开更多
关键词 COVID-19 Big data GIS Spatial transmission Social management
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Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition) 被引量:26
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作者 Hui-Chuan Sun Jian Zhou +77 位作者 Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 《Hepatobiliary Surgery and Nutrition》 SCIE 2022年第2期227-252,I0011-I0014,共30页
Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected pa... Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. 展开更多
关键词 Hepatocellular carcinoma(HCC) conversion therapy surgical resection systematic treatment locoregional treatment CONSENSUS China
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Discrimination of the rare medicinal plant Dendrobium officinale based on naringenin, bibenzyl, and polysaccharides 被引量:26
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作者 CHEN XiaoMe WANG FangFei +4 位作者 WANG yunqiang LI XueLan WANG AiRong WANG ChunLan GUO ShunXing 《Science China(Life Sciences)》 SCIE CAS 2012年第12期1092-1099,共8页
The aim of this study was to establish a method for discriminating Dendrobium officinale from four of its close relatives Den- drobium chrysanthum, Dendrobium erystallinum, Dendrobium aphyllum and Dendrobium devonianu... The aim of this study was to establish a method for discriminating Dendrobium officinale from four of its close relatives Den- drobium chrysanthum, Dendrobium erystallinum, Dendrobium aphyllum and Dendrobium devonianum based on chemical composition analysis. We analyzed 62 samples of 24 Dendrobium species. High performance liquid chromatography analysis confirmed that the four low molecular weight compounds 4',5,7-trihydroxyflavanone (naringenin), 3,4-dihydroxy-4',5-dime- tboxybibenzyl (DDB^2), 3',4-dihydroxy-3,5'-dimethoxybibenzyl (gigantol), and 4,4'-dihydroxy-3,3',5-trimethoxybibenzyl (moscatilin), were common in the genus. The phenol-sulfuric acid method was used to quantify polysaccharides, and the mon- osaccharide composition of the polysaccharides was determined by gas chromatography. Stepwise discriminant analysis was used to differentiate among the five closely related species based on the chemical composition analysis. This proved to be a simple and accurate approach for discriminating among these species. The results also showed that the polysaccharide content, the amounts of the four low molecular weight compounds, and the mannose to glucose ratio, were important factors for species discriminaut. Therefore, we propose that a chemical analysis based on quantification of naringenin, bibenzyl, and polysaccha- rides is effective for identifying D. officinale. 展开更多
关键词 Dendrobium officinale NARINGENIN BIBENZYL POLYSACCHARIDE discriminant analysis
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基于冠状动脉CT血管成像的冠状动脉粥样硬化斑块量化特征及易损性的门诊队列研究 被引量:25
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作者 赵娜 侯志辉 +3 位作者 安云强 高扬 尹卫华 吕滨 《中华放射学杂志》 CAS CSCD 北大核心 2020年第5期467-473,共7页
目的探讨不同年龄组冠状动脉粥样硬化患者的冠状动脉斑块成分及CT易损征象的特点。方法将2017年1至12月于阜外医院门诊就诊,临床疑诊为冠心病并行冠状动脉CT血管成像(CCTA)检查的连续患者纳入单中心的前瞻性队列研究,经排除标准筛选后... 目的探讨不同年龄组冠状动脉粥样硬化患者的冠状动脉斑块成分及CT易损征象的特点。方法将2017年1至12月于阜外医院门诊就诊,临床疑诊为冠心病并行冠状动脉CT血管成像(CCTA)检查的连续患者纳入单中心的前瞻性队列研究,经排除标准筛选后共纳入患者2660例,病变的冠状动脉主要分支血管共5078支。将入组患者及病变血管根据年龄分别分为5组:≤40岁、41~50岁、51~60岁、61~70岁、>70岁组。根据CCTA图像测量并计算各病变冠状动脉的斑块负荷,斑块的脂肪、钙化、纤维成分体积比以及各年龄组斑块CT易损征象的出现比例。分别使用卡方检验及秩和检验比较不同年龄组患者的基线资料差异及各影像参数在不同年龄组的分布特点,同时使用logistic回归法分析冠心病常规危险因素与CT高危斑块的关系。结果斑块的不同成分在各年龄组的变化趋势不同。各年龄组患者的冠状动脉斑块均以纤维成分为主,各组的斑块中纤维成分体积比分别为83.33%(75.42%,91.60%)、81.51%(74.44%,89.07%)、81.85%(74.88%,88.88%)、82.33%(74.03%,89.20%)、80.99%(73.43%,88.19%)(χ2=9.775,P=0.044)。斑块的钙化体积比随年龄增长呈明显上升趋势,各年龄组钙化成分体积比依次为1.10%(0,5.53%)、1.19%(0,7.58%)、2.29%(0,10.45%)、3.97%(0,14.25%)、6.84%(0.40%,17.55%)(χ2=146.719,P<0.001)。脂质体积比则呈先升高后下降的类抛物线变化,以41~50岁组患者的斑块脂质体积比最高,各年龄组冠状动脉斑块的脂质成分体积比分别为10.94%(5.71%,19.31%)、12.18%(5.81%,19.56%)、10.48%(4.83%,17.14%)、8.14%(3.23%,15.11%)、7.20%(2.44%,13.68%)(χ2=137.470,P<0.001)。斑块的CT易损特征分析结果显示,正性重构和低密度斑块征的出现率以及各年龄组粥样硬化斑块中经CT判定为高危斑块的比例均大致随年龄增长呈先上升后下降的单峰曲线变化,以41~50岁年龄组最高(73.9%、91.9%、73.4%)(χ2=8.678、3.970、21. 展开更多
关键词 体层摄影术 X线计算机 冠状动脉疾病 动脉粥样硬化
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B型主动脉夹层患者的临床特点及预后随访 被引量:17
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作者 于易通 任心爽 +5 位作者 尹卫华 安云强 李海彬 马亚南 陈远 吕滨 《中国循环杂志》 CSCD 北大核心 2022年第11期1130-1137,共8页
目的:了解B型主动脉夹层患者的临床特点、预后及长期变化趋势。方法:连续纳入中国医学科学院阜外医院2010~2019年经CT确诊为B型主动脉夹层的933例患者,回顾性分析其临床特点及预后,并总结十年期间的变化趋势。结果:在933例B型主动脉夹... 目的:了解B型主动脉夹层患者的临床特点、预后及长期变化趋势。方法:连续纳入中国医学科学院阜外医院2010~2019年经CT确诊为B型主动脉夹层的933例患者,回顾性分析其临床特点及预后,并总结十年期间的变化趋势。结果:在933例B型主动脉夹层患者中,男性762例(81.7%),平均年龄(50.78±11.81)岁,平均体重指数(26.23±3.95)kg/m2,788例(84.5%)有高血压;男性患者中高血压(86.6%vs.74.9%)、吸烟(56.8%vs.5.3%)较女性患者更常见,而马凡综合征(0.5%vs.4.1%)较少见(P均<0.01)。673例(72.1%)患者就诊时处于急性期,疼痛是最常见的症状(879例,94.2%)。CT显示,146例(15.6%)患者主动脉弓部受累,507例(54.3%)假腔血栓化,253例(27.1%)肾灌注缺损,心包、胸腔积血及纵隔、腹腔血肿等主动脉破裂征象占比均<2.0%;腹腔干、肠系膜上动脉及肾动脉受累比例均<10.0%;男性患者腹腔干、肠系膜上动脉、髂动脉受累比例均明显高于女性患者(分别为:6.8%vs.1.8%;8.7%vs.3.5%;62.6%vs.50.9%;P均<0.05)。不同疾病分期B型主动脉夹层患者的治疗方式均以腔内介入治疗为主。2010~2019年十年期间,有高血压病史及接受药物保守治疗的B型主动脉夹层患者呈增多趋势(P均<0.01)。急性期接受药物保守治疗的B型主动脉夹层患者死亡率明显高于接受手术治疗的患者(12.8%vs.2.5%,P=0.003)。结论:与女性患者相比,男性B型主动脉夹层患者中高血压、吸烟更常见,夹层累及范围更广。2010~2019年十年期间,有高血压病史及接受药物保守治疗的B型主动脉夹层患者呈增多趋势。与药物保守治疗相比,B型主动脉夹层急性期手术治疗的效果更好。 展开更多
关键词 主动脉夹层 临床特点 体层摄影术 X线计算机 预后 队列研究
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CT血流储备分数对心肌缺血病变的诊断效能 被引量:17
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作者 耿文磊 高扬 +11 位作者 赵娜 安云强 徐波 唐熠达 窦克非 慕朝伟 宋雷 胡奉环 尹栋 高立建 张静 吕滨 《中国医学影像技术》 CSCD 北大核心 2020年第2期171-176,共6页
目的以导管测量血流储备分数(FFR)为金标准,评价基于血流动力学优化融合模型的CT血流储备分数(CT-FFR)对冠状动脉狭窄所致心肌缺血病变的诊断效能。方法前瞻性选择127例接受冠状动脉CT血管成像(CCTA)、1周内冠状动脉造影及经导管FFR测... 目的以导管测量血流储备分数(FFR)为金标准,评价基于血流动力学优化融合模型的CT血流储备分数(CT-FFR)对冠状动脉狭窄所致心肌缺血病变的诊断效能。方法前瞻性选择127例接受冠状动脉CT血管成像(CCTA)、1周内冠状动脉造影及经导管FFR测量患者(152支血管),以CCTA观察病变狭窄程度,计算CT-FFR。以FFR<0.8为判断心肌缺血金标准,绘制CT-FFR及CCTA的ROC曲线,获得AUC。计算两种方法诊断心肌缺血的敏感度、特异度、阳性预测值、阴性预测值及准确率。结果 CT-FFR与导管测量FFR一致性良好,仅6.6%测量值在95%一致性界限之外。CT-FFR诊断心肌缺血AUC在患者水平(0.92 vs 0.69,P<0.001)和血管水平(0.93 vs 0.69,P<0.001)均优于CCTA。以患者水平CT-FFR<0.8诊断心肌缺血的敏感度、特异度和准确率分别为84.1%、90.6%和85.8%,CCTA>50%分别为82.5%、54.7%和68.5%;血管水平CT-FFR<0.8分别为88.0%、84.7%和84.9%,CCTA>50%分别为80.6%、57.7%和69.1%。CT-FFR对于血管水平狭窄程度30%~70%病变诊断效能仍佳。结论 CT-FFR对心肌缺血病变的诊断效能优于CCTA,有助于临床筛查心肌缺血病变。 展开更多
关键词 血流储备分数 心肌 心肌缺血 血管造影术 体层摄影术 X线计算机
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Characteristics of the genetic mineralogy of pyrite and its significance for prospecting in the Denggezhuang gold deposit,Jiaodong Peninsula,China 被引量:13
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作者 XUE JianLing LI ShengRong +2 位作者 SUN WenYan ZHANG yunqiang ZHANG Xu 《Science China Earth Sciences》 SCIE EI CAS 2014年第4期644-661,共18页
This paper reports the variation rules for the typomorphic parameters of the pyrite and the gold enrichment rules of the Denggezhuang quartz vein gold deposit at a large-depth scale, providing the mineral signs for de... This paper reports the variation rules for the typomorphic parameters of the pyrite and the gold enrichment rules of the Denggezhuang quartz vein gold deposit at a large-depth scale, providing the mineral signs for deep prospecting prediction through detailed study of the characteristics of crystal' habits, chemical composition, the thermoelectricity of pyrites, and min- eralogical mapping. This paper primarily discusses the correlation between the mineralization intensity and the space-time evolution of the mineralogical parameters, clarifies the physicochemical conditions during gold mineralization, and provides information useful for deep mineralization prediction. We demonstrate that the crystal habits of the pyrites are very complex, primarily occurring as ( 100), (210), and their combinate form. (210) and ( 100)+(210) have positive correlations with gold mineralization, and ( 100)+(210) therefore can be useful for locating rich ore segments. The composition of pyrites is charac- teristically poor in S and rich in As. Their typical trace elements are composed of Mo, As, Pb, Cu, Bi, Zn, Au, Co, Se, Sb, Ag, Ni, Cr, and Te. The average contents of trace elements in pyrites from various stages show that the crystallizing temperature gradually decreased from an early stage to the metallogenic episodes. The precipitation and accumulation of Au and Ag occur primarily in the quartz-pyrite stage (III) and the polymetal minerals stage (IV). The occurrence rate of P-type pyrites (P(%)) is 83.52%. There is a larger dispersion of the thermoelectrical coefficient of pyrite (a) in the Denggezhuang gold deposit than in other deposits in the Jiaodong Peninsula. The electrical conductivity assemblage of pyrites from I to V is characterized by P〉N〉P〉N〉P〉〉N〉P〉〉N〉P〉N, which is usually considered beneficial for mineralization. The relative contents of As+Sb+Se+Te and Co+Ni are closely correlated to P-type and N-type average values and their occurr 展开更多
关键词 crystal habit chemical composition THERMOELECTRICITY PYRITE the Denggezhuang gold deposit Jiaodong
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Geoscience knowledge graph in the big data era 被引量:12
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作者 Chenghu ZHOU Hua WANG +11 位作者 Chengshan WANG Zengqian HOU Zhiming ZHENG Shuzhong SHEN Qiuming CHENG Zhiqiang FENG Xinbing WANG Hairong LV Junxuan FAN Xiumian HU Mingcai HOU yunqiang ZHU 《Science China Earth Sciences》 SCIE EI CSCD 2021年第7期1105-1114,共10页
Since the beginning of the 21 st century,the geoscience research has been entering a significant transitional period with the establishment of a new knowledge system as the core and with the drive of big data as the m... Since the beginning of the 21 st century,the geoscience research has been entering a significant transitional period with the establishment of a new knowledge system as the core and with the drive of big data as the means.It is a revolutionary leap in the research of geoscience knowledge discovery from the traditional encyclopedic discipline knowledge system to the computer-understandable and operable knowledge graph.Based on adopting the graph pattern of general knowledge representation,the geoscience knowledge graph expands the unique spatiotemporal features to the Geoscience knowledge,and integrates geoscience knowledge elements,such as map,text,and number,to establish an all-domain geoscience knowledge representation model.A federated,crowd intelligence-based collaborative method of constructing the geoscience knowledge graph is developed here,which realizes the construction of high-quality professional knowledge graph in collaboration with global geo-scientists.We also develop a method for constructing a dynamic knowledge graph of multi-modal geoscience data based on in-depth text analysis,which extracts geoscience knowledge from massive geoscience literature to construct the latest and most complete dynamic geoscience knowledge graph.A comprehensive and systematic geoscience knowledge graph can not only deepen the existing geoscience big data analysis,but also advance the construction of the high-precision geological time scale driven by big data,the compilation of intelligent maps driven by rules and data,and the geoscience knowledge evolution and reasoning analysis,among others.It will further expand the new directions of geoscience research driven by both data and knowledge,break new ground where geoscience,information science,and data science converge,realize the original innovation of the geoscience research and achieve major theoretical breakthroughs in the spatiotemporal big data research. 展开更多
关键词 Geoscience knowledge graph All-domain geoscience knowledge representation model Federated crowd intelligence collaboration High-precision geological time scale
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基于大样本冠状动脉CT血管成像的单纯先天性冠状动脉异常研究 被引量:10
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作者 马亚南 侯志辉 +4 位作者 安云强 任心爽 于易通 赵娜 吕滨 《中华放射学杂志》 CAS CSCD 北大核心 2021年第9期955-960,共6页
目的利用大样本冠状动脉CT血管成像(CCTA)资料,探讨国人单纯先天性冠状动脉异常(CCAA)的分类与检出率,并简单总结“恶性”异常的CT表现。方法回顾性分析2009年7月至2017年1月在阜外医院行CCTA检查的165133例患者资料,对检出的单纯CCAA... 目的利用大样本冠状动脉CT血管成像(CCTA)资料,探讨国人单纯先天性冠状动脉异常(CCAA)的分类与检出率,并简单总结“恶性”异常的CT表现。方法回顾性分析2009年7月至2017年1月在阜外医院行CCTA检查的165133例患者资料,对检出的单纯CCAA按照冠状动脉起源、开口数目及终点异常进行分类,并统计各类异常的检出率。起源异常包括冠状动脉起源于对侧冠状动脉窦、无冠状动脉窦、主动脉或原冠状动脉窦周围、肺动脉以及回旋支起自对角支;开口数目异常包括单支冠状动脉(SCA)、圆锥支单独开口于右冠状动脉窦、前降支与回旋支双开口;终点异常为冠状动脉瘘(CAF)。其中,冠状动脉起源于对侧冠状动脉窦、冠状动脉起源于肺动脉、SCA、多个或较大的CAF定义为“恶性”异常。结果在165133例CCTA检查中,共发现CCAA 2148例,检出率为1.301%,包括冠状动脉起源异常1302例(0.789%)、开口数目异常298例(0.181%)、终点异常548例(0.332%)。在起源异常中,检出冠状动脉起源于对侧冠状动脉窦700例(0.424%),其中179例血管开口或近段管腔受压而不同程度狭窄,7例不合并冠心病但有明确的心肌缺血或心肌梗死改变。冠状动脉起源于无冠状动脉窦、主动脉或原冠状动脉窦周围分别检出48(0.029%)、531例(0.322%)。冠状动脉起源于肺动脉共检出20例(0.012%),均为左主干起源于肺动脉,均表现为左、右冠状动脉迂曲扩张,左心室增大,5例无冠心病但有明确的心内膜下心肌缺血或心肌梗死改变。冠状动脉开口数目异常中,SCA、圆锥支单独开口于右冠状动脉窦、前降支及回旋支双开口分别检出102(0.062%)、53(0.032%)、143例(0.087%)。102例SCA中,仅有1例表现为心肌缺血且无合并冠心病。CAF共检出548例(0.332%),其中冠状动脉-肺动脉瘘检出率最高,为458例(0.277%),冠状动脉-心房瘘、心室瘘分别检出22(0.013%)、60例(0.036%),另有冠状动� 展开更多
关键词 体层摄影术 X线计算机 冠状动脉异常 单支冠状动脉 冠状动脉瘘
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CT测量左心室心肌应变的可重复性及与超声对照的一致性研究 被引量:9
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作者 马亚南 孟庆超 +4 位作者 王涵 任心爽 于易通 安云强 吕滨 《中华放射学杂志》 CAS CSCD 北大核心 2021年第11期1147-1152,共6页
目的探讨CT特征追踪技术(CT-FT)评估左心室整体心肌应变的可重复性,及与斑点追踪超声心动图(STE)测量结果的相关性和一致性。方法前瞻性纳入2019年11月阜外医院门诊因疑诊冠心病在1周内完成全心动周期冠状动脉CTA(CCTA)和经胸超声心动... 目的探讨CT特征追踪技术(CT-FT)评估左心室整体心肌应变的可重复性,及与斑点追踪超声心动图(STE)测量结果的相关性和一致性。方法前瞻性纳入2019年11月阜外医院门诊因疑诊冠心病在1周内完成全心动周期冠状动脉CTA(CCTA)和经胸超声心动图检查的患者30例。使用CT-FT、STE技术分别分析CT及超声图像的左心室容积和心肌应变,包括舒张末期容积(EDV)、收缩末期容积(ESV)、射血分数(EF)、整体纵向应变(GLS)、整体径向应变(GRS)和整体周向应变(GCS),其中GLS包括心内膜下整体纵向应变(EndoGLS)和心肌整体纵向应变(MyoGLS),GCS包括心内膜下整体周向应变(EndoGCS)和心肌整体周向应变(MyoGCS)。采用ICC评估CT-FT测量参数的观察者内和观察者间的一致性;采用配对样本t检验比较CT-FT与STE不同模式间测量参数的差异,Pearson相关系数分析CT-FT、STE测量结果的相关性,Bland-Altman法分析CT-FT、STE测量结果的一致性。结果CT-FT测量的EDV、ESV、EF、EndoGLS、MyoGLS、GRS、EndoGCS和MyoGCS,观察者内和观察者间测量结果一致性较好(ICC为0.775~0.964,P均<0.001)。CT-FT和STE测量的EF分别为(60.27±8.70)%和(61.22±5.64)%,差异无统计学意义(t=-0.777,P=0.443)。CT-FT测量的EndoGLS、MyoGLS、GRS和MyoGCS分别为(-20.47±4.01)%、(-18.06±3.75)%、(73.90±20.58)%和(-18.48±3.65)%;STE测量的EndoGLS、MyoGLS、GRS和MyoGCS分别为(-18.97±3.33)%、(-16.49±2.60)%、(18.56±3.06)%和(-20.26±4.45)%,差异均具有统计学意义(t值分别为-2.367、-2.945、12.161、2.459,P均<0.05),而CT-FT和STE测量的EndoGCS分别为(-27.78±6.66)%和(-29.18±7.24)%,差异无统计学意义(t=1.246,P=0.223)。两种成像模式测量的EndoGLS、MyoGLS、GRS、EndoGCS、MyoGCS呈中等-强相关,r值分别为0.566、0.629、0.509、0.606、0.539(P均<0.05)。CT-FT与STE测量的EndoGLS、MyoGLS、GRS、EndoGCS、MyoGCS的差值分别为-1.5%、-1.6%、55.3%、1.4%、1.8%、95%一致性界限分别为-8.3%~ 展开更多
关键词 体层摄影术 X线计算机 特征追踪 心肌应变 斑点追踪超声心动图
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中国冠状动脉CT血管成像扫描技术及辐射剂量的现状调查 被引量:8
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作者 任心爽 安云强 +2 位作者 吕滨 李希 李静 《中华放射学杂志》 CAS CSCD 北大核心 2022年第4期405-410,共6页
目的调查2017至2018年我国行冠状动脉CT血管成像(CCTA)检查的扫描方案和及辐射剂量水平。方法根据全国各省市三级医院和二级医院的数量与分布状况进行整群抽样,最终纳入75家医院(二级医院30家、三级医院45家)。对调研医院2017年10月至2... 目的调查2017至2018年我国行冠状动脉CT血管成像(CCTA)检查的扫描方案和及辐射剂量水平。方法根据全国各省市三级医院和二级医院的数量与分布状况进行整群抽样,最终纳入75家医院(二级医院30家、三级医院45家)。对调研医院2017年10月至2018年5月行CCTA检查的患者进行系统抽样,最终纳入1312例患者。收集患者的临床资料(年龄、性别、体质量等)及CCTA检查的资料(扫描前准备情况、扫描参数、图像采集模式、后处理方案及辐射剂量等),并采用Wilcoxon秩和检验、χ^(2)检验分析各指标的应用情况及相应扫描方案下的有效辐射剂量(ED)。结果低管电压(≤100 kV)应用比例为35.4%(464/1312),其中三级医院应用低管电压的比例在患者体质量<60 kg组、60~90 kg组及>90 kg组分别为45.0%(126/280)、39.6%(256/647)和33.3%(8/24),均较二级医院[27.8%(25/90)、18.5%(49/265)、0(0/6)]高,差异具有统计学意义(χ^(2)=34.25、51.05、207.05,P<0.001)。前瞻性心电门控扫描模式应用比例为38.5%(505/1312)。迭代重建技术的应用比例为82.5%(1082/1312),应用迭代重建的患者中仍有58.8%(636/1082)的患者应用120 kV及以上的管电压。CCTA检查的ED为11.84(6.33,16.66)mSv。三级医院行CCTA检查的ED较二级医院的ED低(Z=-5.73,P<0.001)。前瞻性心电门控下ED较回顾性心电门控的ED低(Z=-15.76,P<0.001)。应用迭代重建的ED较未用迭代重建的ED低(Z=-3.45,P=0.004)。结论调研医院CCTA检查均存在管电压固定化、低管电压和前瞻性心电门控应用比例低、迭代重建技术应用不规范的问题,且扫描方案的不规范是导致CCTA检查时ED高的重要原因。尽管三级医院的扫描规范性高于二级医院,但仍未达到指南要求水平。 展开更多
关键词 体层摄影术 X线计算机 冠状动脉疾病 辐射剂量 扫描技术
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A survey of remote sensing image classification based on CNNs 被引量:8
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作者 Jia Song Shaohua Gao +1 位作者 yunqiang Zhu Chenyan Ma 《Big Earth Data》 EI 2019年第3期232-254,共23页
With the development of earth observation technologies,the acquired remote sensing images are increasing dramatically,and a new era of big data in remote sensing is coming.How to effectively mine these massive volumes... With the development of earth observation technologies,the acquired remote sensing images are increasing dramatically,and a new era of big data in remote sensing is coming.How to effectively mine these massive volumes of remote sensing data are new challenges.Deep learning provides a new approach for analyzing these remote sensing data.As one of the deep learning models,convolutional neural networks(CNNs)can directly extract features from massive amounts of imagery data and is good at exploiting semantic features of imagery data.CNNs have achieved remarkable success in computer vision.In recent years,quite a few researchers have studied remote sensing image classification using CNNs,and CNNs can be applied to realize rapid,economical and accurate analysis and feature extraction from remote sensing data.This paper aims to provide a survey of the current state-of-the-art application of CNN-based deep learning in remote sensing image classification.We first briefly introduce the principles and characteristics of CNNs.We then survey developments and structural improvements on CNN models that make CNNs more suitable for remote sensing image classification,available datasets for remote sensing image classification,and data augmentation techniques.Then,three typical CNN application cases in remote sensing image classification:scene classification,object detection and object segmentation are presented.We also discuss the problems and challenges of CNN-based remote sensing image classification,and propose corresponding measures and suggestions.We hope that the survey can facilitate the advancement of remote sensing image classification research and help remote-sensing scientists to tackle classification tasks with the state-of-art deep learning algorithms and techniques. 展开更多
关键词 CNNS deep learning neural network remote sensing CLASSIFICATION
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基于动态心肌灌注CT成像的无冠状动脉病变人群定量心肌血流灌注参数分析 被引量:7
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作者 赵娜 马伟 +3 位作者 耿文磊 安云强 吕滨 高扬 《中华医学杂志》 CAS CSCD 北大核心 2021年第39期3195-3201,共7页
目的基于动态心肌灌注CT成像(CTP),探究冠状动脉无狭窄者心肌灌注定量参数[心肌血流量(MBF)、心肌血容量(MBV)]的数值范围。方法前瞻性纳入2018年12月至2019年9月因偶有胸闷或冠心病家族史至中国医学科学院阜外医院放射科行冠状动脉CT... 目的基于动态心肌灌注CT成像(CTP),探究冠状动脉无狭窄者心肌灌注定量参数[心肌血流量(MBF)、心肌血容量(MBV)]的数值范围。方法前瞻性纳入2018年12月至2019年9月因偶有胸闷或冠心病家族史至中国医学科学院阜外医院放射科行冠状动脉CT成像检查并经其证实无冠状动脉粥样硬化病变且自愿行动态CTP检查的34例受试者,其中男15例,女19例,年龄33~65(50±7)岁。入组受试者先后行静息-负荷动态CTP检查。依据心肌17段分段法,计算心肌各节段MBF、MBV值。统计分析整体水平无冠状动脉病变受试者的MBF、MBV参数值范围,并比较不同性别及不同冠状动脉供血区定量参数的差异。结果冠状动脉无狭窄者静息和负荷状态下的整体MBF、MBV值分别为(115.5±27.4)ml·100 g^(-1)·min^(-1)、(212.8±40.8)ml·100 g^(-1)·min^(-1)及(17.6±4.0)ml/100 g、(25.8±4.6)ml/100 g。右冠状动脉供血区MBF、MBV的绝对及相对储备值[MBF:(102.8±41.5)ml·100 g^(-1)·min^(-1)、107.7%±52.5%,MBV:(9.3±5.2)ml/100 g、62.1%±47.4%]均最高,但三支冠状动脉供血区参数的差异不具有统计学意义(均P>0.05)。女性负荷状态MBF[(228.6±39.9)ml·100 g^(-1)·min^(-1)]及MBF绝对储备值[(113.3±46.2)ml·100 g^(-1)·min^(-1)]显著高于男性[(192.8±33.4)ml·100 g^(-1)·min^(-1)、(77.0±41.2)ml·100 g^(-1)·min^(-1)](均P<0.05)。女性MBF相对储备、静息态MBⅤ、负荷态MBV及MBV绝对储备和相对储备值均高于男性,但差异无统计学意义(均P>0.05)。结论冠状动脉无狭窄者静息和负荷状态下的MBF为(115.5±27.4)ml·100 g^(-1)·min^(-1)、(212.8±40.8)ml·100 g^(-1)·min^(-1),MBV平均值为(17.6±4.0)ml/100 g、(25.8±4.6)ml/100 g。女性负荷状态MBF及MBF绝对储备值高于男性。 展开更多
关键词 体层摄影术 X线计算机 心肌灌注成像 冠状动脉病变
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Effect of vernalization on tuberization and flowering in the Tibetan turnip is associated with changes in the expression of FLC homologues 被引量:7
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作者 Yan Zheng Landi Luo +4 位作者 Yuanyuan Liu yunqiang Yang Chuntao Wang Xiangxiang Kong Yongping Yang 《Plant Diversity》 SCIE CAS CSCD 2018年第2期50-56,共7页
The turnip(Brassica rapa var. rapa) is a biennial crop that is planted in late summer/early fall and forms fleshy tubers for food in temperate regions. The harvested tubers then overwinter and are planted again the ne... The turnip(Brassica rapa var. rapa) is a biennial crop that is planted in late summer/early fall and forms fleshy tubers for food in temperate regions. The harvested tubers then overwinter and are planted again the next spring for flowering and seeds. FLOWERING LOCUS C(FLC) is a MADS-box transcription factor that acts as a major repressor of floral transition by suppressing the flowering promoters FT and SOC1. Here we show that vernalization effectively represses tuber formation and promotes flowering in Tibetan turnip. We functionally characterized four FLC homologues(BrrFLC1,FLC2, FLC3, and FLC5), and found that BrrFLC2 and BrrFLC1 play a major role in repressing flowering in turnip and in transgenic Arabidopsis. In contrast, tuber formation was correlated with BrrFLC1 expression in the hypocotyl and was repressed under cold treatment following the quantitative downregulation of BrrFLC1. Grafting experiments of non-vernalized and vernalized turnips revealed that vernalization independently suppressed tuberization in the tuber or hypocotyl of the rootstock or scion, which occurred in parallel with the reduction in BrrFLC1 activity. Together, our results demonstrate that the Tibetan turnip is highly responsive to cold exposure, which is associated with the expression levels of BrrFLC genes. 展开更多
关键词 Tibetan turnip TUBERIZATION FLOWERING BrrFLC genes VERNALIZATION
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Knowledge System,Ontology,and Knowledge Graph of the Deep-Time Digital Earth(DDE): Progress and Perspective 被引量:6
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作者 Xiumian Hu Yiwei Xu +7 位作者 Xiaogang Ma yunqiang Zhu Chao Ma Chao Li Hairong Xinbing Wang Chenghu Zhou Chengshan Wang 《Journal of Earth Science》 SCIE CAS CSCD 2023年第5期1323-1327,共5页
THE USE OF KNOWLEDGE GRAPH IN NATURAL SCIENCE Knowledge graph is a field of Artificial Intelligence(AI)that aims to represent knowledge in the form of graphs,consisting of nodes and edges which represent entities and ... THE USE OF KNOWLEDGE GRAPH IN NATURAL SCIENCE Knowledge graph is a field of Artificial Intelligence(AI)that aims to represent knowledge in the form of graphs,consisting of nodes and edges which represent entities and relationships between nodes respectively(Aidan et al.,2022).Although the knowledge graph was popularized recently due to use of this idea in Google’s search engine in 2012(Amit,2012),its root can be traced back to the emergence of the Semantic Web as well as earlier works in ontology(Aggarwal,2021). 展开更多
关键词 DDE Google Web SEMANTIC
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采用冠状动脉CTA探究血压对主动脉根部及升主动脉的影响 被引量:7
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作者 王翔 侯志辉 +8 位作者 安云强 于易通 任心爽 李珈含 王欣 方伟 王义勋 刘林祥 吕滨 《国际医学放射学杂志》 北大核心 2019年第3期274-278,共5页
目的应用冠状动脉CT血管成像(CCTA)探究血压正常者与高血压病人主动脉根部及升主动脉内径的差异,为早期筛查与诊断高血压病人主动脉根部相关疾病提供数据支持。方法回顾性分析2017年1月—6月因疑诊冠心病行CCTA检查的971例病人。其中既... 目的应用冠状动脉CT血管成像(CCTA)探究血压正常者与高血压病人主动脉根部及升主动脉内径的差异,为早期筛查与诊断高血压病人主动脉根部相关疾病提供数据支持。方法回顾性分析2017年1月—6月因疑诊冠心病行CCTA检查的971例病人。其中既往明确诊断为高血压者694例,男388例,平均年龄(53.7±10.3)岁;女306例,平均年龄(58.9±8.5)岁。血压正常且无高血压病史者277例,男165例,平均年龄(52.8±10.1)岁;女112例,平均年龄(58.8±6.8)岁。选用CCTA中心脏收缩期影像,测量主动脉根部及升主动脉4个层面(即主动脉瓣环层面、瓦氏窦层面、窦管交界层面和升主动脉于肺动脉分叉层面)上的管腔内径。采用独立样本t检验比较不同性别高血压组和血压正常组间各个内径测量值的差异。结果血压正常的男性主动脉瓣环短径和长径、瓦氏窦最大内径、窦管交界处内径均高于女性(均P<0.05),升主动脉内径差异无统计学意义(P>0.05)。男性和女性高血压组的升主动脉内径均高于血压正常组(均P<0.05),而高血压组和血压正常组间主动脉瓣环长径、短径,瓦氏窦最大内径,窦管交界处内径差异均无统计学意义(均P>0.05)。结论高血压可以引起升主动脉的显著扩张。 展开更多
关键词 高血压 主动脉根部 升主动脉 冠状动脉CT血管成像
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冠状动脉低开口患者行经导管主动脉瓣置换术的结果分析 被引量:6
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作者 牛冠男 王墨扬 +10 位作者 赵庆豪 张倩 叶蕴青 宋光远 张洪亮 罗彤 滕思勇 赵杰 安云强 吕滨 吴永健 《中国循环杂志》 CSCD 北大核心 2022年第4期356-361,共6页
目的:分析冠状动脉低开口(≤10 mm)的症状性重度主动脉瓣狭窄患者接受经导管主动瓣置换术(TAVR)治疗的有效性及安全性。方法:选择2012年12月至2021年12月中国医学科学院阜外医院行TAVR治疗的患者622例,分为冠状动脉开口高度>10 mm组(... 目的:分析冠状动脉低开口(≤10 mm)的症状性重度主动脉瓣狭窄患者接受经导管主动瓣置换术(TAVR)治疗的有效性及安全性。方法:选择2012年12月至2021年12月中国医学科学院阜外医院行TAVR治疗的患者622例,分为冠状动脉开口高度>10 mm组(n=556);冠状动脉开口高度≤10 mm组(n=66,均经术前影像学筛选,排除冠状动脉阻塞高风险后接受TAVR治疗);对两组患者的基线临床资料、手术方法及效果进行回顾性分析。结果:两组患者各项基线临床资料差异均无统计学意义(P均>0.05)。全部患者早期手术成功率较高(83.28%);冠状动脉开口高度≤10 mm组和冠状动脉开口高度>10 mm组术中使用第二枚瓣膜、术后早期植入起搏器、早期全因死亡、脑卒中、严重血管并发症发生率差异均无统计学意义(P均>0.05)。与术前比较,两组患者术后主动脉瓣平均跨瓣压差均明显减低(P<0.01),主动脉瓣瓣口面积均明显扩大(P<0.01),但两组间比较差异均无统计学意义(P均>0.05)。冠状动脉阻塞发生率两组间差异无统计学意义(0.72%vs.0%,P=0.49)。冠状动脉开口高度≤10 mm组需要进行冠状动脉保护的患者比例较冠状动脉开口高度>10 mm组明显增高(6.06%vs.1.44%,P<0.01),经冠状动脉保护后无患者出现冠状动脉阻塞或围术期死亡、脑卒中等并发症。结论:经术前细致影像学筛选的冠状动脉低开口患者接受TAVR治疗安全、有效。对冠状动脉低开口患者结合形态学特征、冠状动脉开口水平瓣叶结构及窦部宽度评估冠状动脉阻塞风险,并进行适当冠状动脉保护,是避免冠状动脉阻塞的可行方法。 展开更多
关键词 主动脉瓣狭窄 经导管主动脉瓣置换术 冠状动脉阻塞 冠状动脉保护
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Optimal Coordination Control Strategy of Hybrid Energy Storage Systems for Tie-line Smoothing Services in Integrated Community Energy Systems 被引量:5
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作者 Dan Wang yunqiang Zhi +4 位作者 Bo Yu Zhaoyu Chen Qingsong An Ling Cheng Menghua Fan 《CSEE Journal of Power and Energy Systems》 SCIE 2018年第4期408-416,共9页
Increasing renewable energy penetration into integrated community energy systems(ICESs)requires more efficient methods to prevent power fluctuations of the tie–line(connection of the ICESs to the main grid).In this p... Increasing renewable energy penetration into integrated community energy systems(ICESs)requires more efficient methods to prevent power fluctuations of the tie–line(connection of the ICESs to the main grid).In this paper,centrally-controlled air conditioners are considered as a virtual energy storage system(VESS).The optimal thermostat regulation is used to manage the charging/discharging power of the VESS within the customer comfort level range and the virtual state of charge(VSOC)is used to describe the charging/discharging power of the VESS.On this basis,the model of the hybrid energy storage system is built with a VESS and a battery storage system(BSS).Then,an optimal coordination control strategy(OCCS)for a hybrid energy storage system is developed considering the state-space equation to describe the OCCS,the constraints of the OCCS,and the objective function to express the optimal coordination control performance.Finally,the influence of the outdoor temperature and the deadband of air conditioners on the results of the OCCS is analyzed.Results show that the OCCS can realize optimal allocation of the storage response amount to trace the reference target accurately and guarantee both the state of charge(SOC)of the batteries in a reasonable range to prolong the battery life and ensure the level of comfort experienced by users. 展开更多
关键词 Battery storage system optimal coordination control power fluctuation renewable energy virtual energy storage system
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