The accumulation of reactive oxygen species （ROS） is involved in plant cell development. In plant, class III peroxidases are heme-containing enzymes encoded by a large multi-gene family participated in the release o...The accumulation of reactive oxygen species （ROS） is involved in plant cell development. In plant, class III peroxidases are heme-containing enzymes encoded by a large multi-gene family participated in the release or consumption of ROS. The specific function of each member of the family is still elusive. Here, we showed that ROS was significantly generated during cotton fiber initiation and elongation, whereas, application of NADPH oxidase inhibitor diphenyleneiodonium （DPI） and peroxidase inhibitor salicylhydroxamic acid （SHAM） to the wild-type cotton ovule culture significantly suppressed fiber growth, respectively. Their inhibitory effects were caused by the reduction of superoxide radical （O2^-）. Ten GhPOX genes （cDNAs） encoding cotton class III peroxidases were isolated, among them eight GhPOX genes were reported for the first time. Microarray analyses indicated that GhPOX1 was the mostly predominantly expressed in fast-elongating cotton fiber cells. Real-time quantitative PCR analysis revealed the transcript level of GhPOX1 was over 400-fold higher in growing fiber cells than in ovules, flowers, roots, stems and leaves. To reveal the role of GhPOX1 in plant development, its Arabidopsis orthologue atpox13 mutant was demonstrated to be defective in branch root development. Taken together, the data suggest that GhPOX1 plays an important role during fiber cell elongation possibly by mediating production of reactive oxygen species.展开更多
目的:探讨远程血压监测管理模式相较于传统血压管理模式对高血压患者的管理效果。方法:本研究为多中心前瞻性研究,选取2020年12月—2021年6月于青岛大学附属心血管病医院、青岛大学附属医院崂山院区、青岛新民生医院、青岛安康医院及青...目的:探讨远程血压监测管理模式相较于传统血压管理模式对高血压患者的管理效果。方法:本研究为多中心前瞻性研究,选取2020年12月—2021年6月于青岛大学附属心血管病医院、青岛大学附属医院崂山院区、青岛新民生医院、青岛安康医院及青岛博泰医院门诊治疗的高血压患者414例,分为远程组(147例)、非远程组(135例)和常规组(132例)。其中远程组采用远程血压管理模式进行血压管理,包括应用可上传数据的血压计测量血压,接受远程教育、远程健康指导等;非远程组应用血压计,但被关闭远程功能;常规组按照传统血压管理模式进行管理。干预6个月后对比3组诊室血压、家庭自测血压、血压变异性、生活方式及用药情况。结果:与常规组及非远程组比较,远程组干预后诊室收缩压[(136.6±16.0)、(135.2±13.9)mmHg vs (131.6±13.6) mmHg(1 mmHg=0.133 kPa),P=0.004、0.041]和舒张压[(83.0±9.7)、(82.8±9.5) mmHg vs (79.7±9.3) mmHg,P=0.003、0.006]均降低,血压达标率(53%、54.1%vs 68.0%,均P<0.05)升高。与非远程组比较,远程组干预后家庭自测收缩压[(130.6±10.3) mmHg vs (127.7±10.3) mmHg,P=0.016]、舒张压[(81.5±6.7) mmHg vs (79.1±9.0) mmHg,P=0.010]、收缩压标准差[5.9(4.9,7.3) mmHg vs 5.4(3.8,7.0),P=0.009]、舒张压标准差[4.9(4.3,5.8) mmHg vs 4.0(2.9,5.3) mmHg,P<0.001]、收缩压变异系数[0.044(0.037,0.058) vs 0.041(0.030,0.056),P=0.043]、舒张压变异系数[0.060(0.051,0.072) vs 0.051(0.038,0.067),P<0.001]均降低。与常规组比较,远程组干预后饮酒情况(P=0.02)、运动情况(P=0.019)有所改善,不用药比例降低(P<0.05),单片复方制剂应用率增高(P<0.05);与非远程组比较,远程组饮酒情况(P=0.024)有改善,不用药比例降低(P<0.05)。结论:远程血压监测管理模式相较于传统血压管理模式对高血压患者的综合管理起到更好的效果。展开更多
Lidar based on the optical phased array(OPA)and frequency-modulated continuous wave(FMCW)technology stands out in automotive applications due to its all-solid-state design,high reliability,and remarkable resistance to...Lidar based on the optical phased array(OPA)and frequency-modulated continuous wave(FMCW)technology stands out in automotive applications due to its all-solid-state design,high reliability,and remarkable resistance to interference.However,while FMCW coherent detection enhances the interference resistance capabilities,it concurrently results in a significant increase in depth computation,becoming a primary constraint for improving point cloud density in such perception systems.To address this challenge,this study introduces a lidar solution leveraging the flexible scanning characteristics of OPA.The proposed system categorizes target types within the scene based on RGB images.Subsequently,it performs scans with varying angular resolutions depending on the importance of the targets.Experimental results demonstrate that,compared to traditional scanning methods,the target-adaptive method based on semantic segmentation reduces the number of points to about one-quarter while maintaining the resolution of the primary target area.Conversely,with a similar number of points,the proposed approach increases the point cloud density of the primary target area by about four times.展开更多
基金supported by grants from the National Basic Research Program of China (No. 2004CB117302)the National High-tech Research Program of China (No. 2006AA10A109-1 and 2007AA10Z136).
文摘The accumulation of reactive oxygen species （ROS） is involved in plant cell development. In plant, class III peroxidases are heme-containing enzymes encoded by a large multi-gene family participated in the release or consumption of ROS. The specific function of each member of the family is still elusive. Here, we showed that ROS was significantly generated during cotton fiber initiation and elongation, whereas, application of NADPH oxidase inhibitor diphenyleneiodonium （DPI） and peroxidase inhibitor salicylhydroxamic acid （SHAM） to the wild-type cotton ovule culture significantly suppressed fiber growth, respectively. Their inhibitory effects were caused by the reduction of superoxide radical （O2^-）. Ten GhPOX genes （cDNAs） encoding cotton class III peroxidases were isolated, among them eight GhPOX genes were reported for the first time. Microarray analyses indicated that GhPOX1 was the mostly predominantly expressed in fast-elongating cotton fiber cells. Real-time quantitative PCR analysis revealed the transcript level of GhPOX1 was over 400-fold higher in growing fiber cells than in ovules, flowers, roots, stems and leaves. To reveal the role of GhPOX1 in plant development, its Arabidopsis orthologue atpox13 mutant was demonstrated to be defective in branch root development. Taken together, the data suggest that GhPOX1 plays an important role during fiber cell elongation possibly by mediating production of reactive oxygen species.
文摘目的:探讨远程血压监测管理模式相较于传统血压管理模式对高血压患者的管理效果。方法:本研究为多中心前瞻性研究,选取2020年12月—2021年6月于青岛大学附属心血管病医院、青岛大学附属医院崂山院区、青岛新民生医院、青岛安康医院及青岛博泰医院门诊治疗的高血压患者414例,分为远程组(147例)、非远程组(135例)和常规组(132例)。其中远程组采用远程血压管理模式进行血压管理,包括应用可上传数据的血压计测量血压,接受远程教育、远程健康指导等;非远程组应用血压计,但被关闭远程功能;常规组按照传统血压管理模式进行管理。干预6个月后对比3组诊室血压、家庭自测血压、血压变异性、生活方式及用药情况。结果:与常规组及非远程组比较,远程组干预后诊室收缩压[(136.6±16.0)、(135.2±13.9)mmHg vs (131.6±13.6) mmHg(1 mmHg=0.133 kPa),P=0.004、0.041]和舒张压[(83.0±9.7)、(82.8±9.5) mmHg vs (79.7±9.3) mmHg,P=0.003、0.006]均降低,血压达标率(53%、54.1%vs 68.0%,均P<0.05)升高。与非远程组比较,远程组干预后家庭自测收缩压[(130.6±10.3) mmHg vs (127.7±10.3) mmHg,P=0.016]、舒张压[(81.5±6.7) mmHg vs (79.1±9.0) mmHg,P=0.010]、收缩压标准差[5.9(4.9,7.3) mmHg vs 5.4(3.8,7.0),P=0.009]、舒张压标准差[4.9(4.3,5.8) mmHg vs 4.0(2.9,5.3) mmHg,P<0.001]、收缩压变异系数[0.044(0.037,0.058) vs 0.041(0.030,0.056),P=0.043]、舒张压变异系数[0.060(0.051,0.072) vs 0.051(0.038,0.067),P<0.001]均降低。与常规组比较,远程组干预后饮酒情况(P=0.02)、运动情况(P=0.019)有所改善,不用药比例降低(P<0.05),单片复方制剂应用率增高(P<0.05);与非远程组比较,远程组饮酒情况(P=0.024)有改善,不用药比例降低(P<0.05)。结论:远程血压监测管理模式相较于传统血压管理模式对高血压患者的综合管理起到更好的效果。
基金National Key Research and Development Program of China(2022YFB2804502,2022YFB2804504)National Natural Science Foundation of China(61934003,62090054)+2 种基金Major Scientific and Technological Program of Jilin Province(20210301014GX)Jilin Provincial Development and Reform Commission Project(2020C056)Program for Jilin University Science and Technology Innovative Research Team(JLUSTIRT,2021TD-39)。
文摘Lidar based on the optical phased array(OPA)and frequency-modulated continuous wave(FMCW)technology stands out in automotive applications due to its all-solid-state design,high reliability,and remarkable resistance to interference.However,while FMCW coherent detection enhances the interference resistance capabilities,it concurrently results in a significant increase in depth computation,becoming a primary constraint for improving point cloud density in such perception systems.To address this challenge,this study introduces a lidar solution leveraging the flexible scanning characteristics of OPA.The proposed system categorizes target types within the scene based on RGB images.Subsequently,it performs scans with varying angular resolutions depending on the importance of the targets.Experimental results demonstrate that,compared to traditional scanning methods,the target-adaptive method based on semantic segmentation reduces the number of points to about one-quarter while maintaining the resolution of the primary target area.Conversely,with a similar number of points,the proposed approach increases the point cloud density of the primary target area by about four times.
